G-protein-coupled receptor kinase-5 mediates inflammation but does not regulate cellular infiltration or bacterial load in a polymicrobial sepsis model in mice

Journal of Innate Immunity

Volumn 5, Issue 4, 2013, Pages 401-413

  Packiriswamy, Nandakumar ^a   Lee, Taehyung ^a   Raghavendra, Pongali B ^a   Durairaj, Haritha ^a   Wang, Hongbing ^a   Parameswaran, Narayanan ^a  

^a MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

Apoptosis; Cytokines; Host defense; Immune response; Macrophages; Sepsis; Septic shock; Toll like receptor

Indexed keywords

CEFTRIAXONE; CORTICOSTERONE; CYTOKINE; G PROTEIN COUPLED RECEPTOR KINASE 5; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; METRONIDAZOLE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC THERAPY; APOPTOSIS; ARTICLE; BACTERIAL LOAD; CELL INFILTRATION; CHEMOTAXIS; CORTICOSTERONE BLOOD LEVEL; ENZYME DEFICIENCY; ENZYME INHIBITION; GENE EXPRESSION; GENOTYPE; IN VIVO STUDY; MALE; MORTALITY; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SEPSIS; THYMOCYTE; BACTERIAL COUNT; CONTROLLED STUDY; CYTOKINE PRODUCTION; IMMOBILIZATION STRESS; IMMUNOCOMPETENT CELL; IN VITRO STUDY; INFLAMMATION; INTRACELLULAR SIGNALING; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BACTERIAL LOAD; CECUM; CELL MOVEMENT; CELLS, CULTURED; CORTICOSTERONE; DISEASE MODELS, ANIMAL; G-PROTEIN-COUPLED RECEPTOR KINASE 5; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION; LIVER; MALE; MICE; MICE, KNOCKOUT; NF-KAPPA B; SEPSIS; SIGNAL TRANSDUCTION; THYMOCYTES;

EID: 84879411122     PISSN: 1662811X     EISSN: 16628128     Source Type: Journal    
DOI: 10.1159/000347002     Document Type: Article

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