Cardiac βARK1 inhibition prolongs survival and augments β blocker therapy in a mouse model of severe heart failure

Proceedings of the National Academy of Sciences of the United States of America

Volumn 98, Issue 10, 2001, Pages 5809-5814

  Harding, Victoria B ^a   Jones, Larry R ^b   Lefkowitz, Robert J ^a   Koch, Walter J ^a   Rockman, Howard A ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; BETA ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALSEQUESTRIN; METOPROLOL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ECHOCARDIOGRAPHY; ENZYME ACTIVITY; GENE OVEREXPRESSION; HEART DILATATION; HEART FAILURE; HEART FUNCTION; LIGAND BINDING; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; SURVIVAL RATE; TRANSGENIC MOUSE;

ADRENERGIC BETA-ANTAGONISTS; ANIMALS; BETA-ADRENERGIC RECEPTOR KINASE; CARDIOMYOPATHY, DILATED; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DISEASE MODELS, ANIMAL; MICE; MICE, TRANSGENIC; MYOCARDIUM;

ANIMALIA; MUS MUSCULUS;

EID: 0035826710     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.091102398     Document Type: Article

References (28)

1. Lefkowitz, R. J. (1993) Cell 74, 409-412.
2. Bristow, M. R., Ginsburg, R., Minobe, W., Cubicciotti, R. S., Sageman, W. S., Lurie, K., Billingham, M. E., Harrison, D. C. & Stinson, E. B. (1982) N. Engl. J. Med. 307, 205-211.
3. Ungerer, M., Bohm, M., Elce, J. S., Erdmann, E. & Lohse, M, J. (1993) Circulation 87, 454-463.
4. Rockman, H. A., Chien, K. R., Choi, D. J., Iaccarino, G., Hunter, J. J., Ross, J., Jr., Lefkowitz, R. J. & Koch, W. J. (1998) Proc. Natl. Acad. Sci. USA 95, 7000-7005.
5. Koch, W. J., Rockman, H. A., Samama, P., Hamilton, R. A., Bond, R. A., Milano, C. A. & Lefkowitz, R. J. (1995) Science 268, 1350-1353.
6. White, D. C., Hata, J. A., Shah, A. S., Glower, D. D., Lefkowitz, R. J. & Koch, W. J. (2000) Proc. Natl. Acad. Sci. USA 97, 5428-5433. (First Published April 25, 2000; 10.1073/pnas.090091197)
7. Jones, L. R., Suzuki, Y. J., Wang, W., Kobayashi, Y. M., Ramesh, V., Franzini-Armstrong, C., Cleemann, L. & Morad, M. (1998) J. Clin. Invest. 101, 1385-1393.
8. Cho, M. C., Rapacciuolo, A., Koch, W. J., Kobayashi, Y., Jones, L. R. & Rockman, H. A. (1999) J. Biol. Chem. 274, 22251-22256.
9. Esposito, G., Santana, L. F., Dilly, K., Cruz, J. D., Mao, L., Lederer, W. J. & Rockman, H. A. (2000) Am. J. Physiol. 279, H3101-H3112.
10. Choi, D. J., Koch, W. J., Hunter, J. J. & Rockman, H. A. (1997) J. Biol. Chem. 272, 17223-17229.
11. Packer, M., Bristow, M. R., Cohn, J. N., Colucci, W. S., Fowler, M. B., Gilbert, E. M. & Shusterman, N. H. (1996) N. Engl. J. Med. 334, 1349-1355.
12. Hjalmarson, A., Goldstein, S., Fagerberg, B., Wedel, H., Waagstein, F., Kjekshus, J., Wikstrand, J., El Allaf, D., Vitovec, J., Aldershvile, J., et al. (2000) J. Am. Med. Assoc. 283, 1295-1302.
13. Hart, S. M. (2000) Ann. Pharmacother. 34, 1440-1451.
14. Packer, M. (1997) Am. J. Cardiol. 80, 46L-54L.
15. Garg, R. & Yusuf, S. (1995) J. Am. Med. Assoc. 273, 1450-1456.
16. Roth, D. M., Gao, M. H., Lai, N. C., Drumm, J., Dalton, N., Zhou, J. Y., Zhu, J., Entrikin, D. & Hammond, H. K. (1999) Circulation 99, 3099-3102.
17. Asai, K., Yang, G. P., Geng, Y. J., Takagi, G., Bishop, S., Ishikawa, Y., Shannon, R. P., Wagner, T. E., Vatner, D. E., Homcy, C. J. & Vatner, S. F. (1999) J. Clin. Invest. 104, 551-558.
18. Sato, Y., Kiriazis, H., Yatani, A., Schmidt, A. G., Hahn, H., Ferguson, D. G., Sako, H., Mitarai, S., Honda, R., Mesnard-Rouiller, L., et al. (2001) J. Biol. Chem. 276, 9392-9399.
19. Betkowski, A. S. & Hauptman, P. J. (2000) Curr. Opin. Cardiol. 15, 293-303.
20. Pitt, B., Segal, R., Martinez, F. A., Meurers, G., Cowley, A. J., Thomas, I., Deedwania, P. C., Ney, D. E., Snavely, D. B. & Chang, P. I. (1997) Lancet 349, 747-752.
21. Sakai, S., Miyauchi, T., Kobayashi, M., Yamaguchi, I., Goto, K. & Sugishita, Y. (1996) Nature (London) 384, 353-355.
22. Tang, W. J. & Gilman, A. G. (1992) Cell 70, 869-872.
23. Clapham, D. E. & Neer, E. J. (1993) Nature (London) 365, 403-406.
24. Luttrell, L. M., Ferguson, S. S., Daaka, Y., Miller, W. E., Maudsley, S., Della Rocca, G. J., Lin, F., Kawakatsu, H., Owada, K., Luttrell, D. K., et al. (1999) Science 283, 655-661.
25. Naga Prasad, S. V., Esposito, G., Mao, L., Koch, W. J. & Rockman, H. A. (2000) J. Biol. Chem. 275, 4693-4698.
26. Knollmann, B. C., Knollmann-Ritschel, B. E., Weissman, N. J., Jones, L. R. & Morad, M. (2000) J. Physiol. (London) 525 Pt. 2, 483-498.
27. Engelhardt, S., Hein, L., Wiesmann, F. & Lohse, M. J. (1999) Proc. Natl. Acad. Sci. USA 96, 7059-7064.
28. Liggett, S. B., Tepe, N. M., Lorenz, J. N., Canning, A. M., Jantz, T. D., Mitarai, S., Yatani, A. & Dorn, G. W. (2000) Circulation 101, 1707-1714.