G protein-coupled receptor kinase GRK2 is a phospholipid-dependent enzyme that can be conditionally activated by G protein βγ subunits

Journal of Biological Chemistry

Volumn 271, Issue 37, 1996, Pages 22552-22562

  DebBurman, Shubhik K ^a   Ptasienski, Judy ^a   Benovic, Jeffrey L ^b   Hosey, M Marlene ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; MUSCARINIC M2 RECEPTOR; PHOSPHATIDYLINOSITOL 4 PHOSPHATE; PHOSPHOLIPID; PROTEIN KINASE; RECEPTOR PROTEIN;

ARTICLE; BETA CHAIN; ENZYME ACTIVATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

ADENOSINE TRIPHOSPHATE; ANIMALS; BETA-ADRENERGIC RECEPTOR KINASE; CELLS, CULTURED; CHICK EMBRYO; CRICETINAE; CRICETULUS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENZYME ACTIVATION; GTP-BINDING PROTEINS; HUMANS; INOSITOL 1,4,5-TRISPHOSPHATE; MYOCARDIUM; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; PHOSPHATIDYLINOSITOL PHOSPHATES; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, MUSCARINIC M2; RECEPTORS, MUSCARINIC; RHODOPSIN; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0029788099     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.37.22552     Document Type: Article

References (79)

1. Sibley, D. R., Benovic, J. L., Caron, M. G., and Lefkowitz, R. J. (1987) Cell 48, 914-922
2. Liggett, S. B., and Lefkowitz, R. J. (1994) in Regulation of Signal Transduction Pathways by Desensitization and Amplification (Sibley, D. R., and Houslay, M. D., eds) pp. 71-98, John Wiley & Sons, New York
3. Hargrave, P., and Hamm, H. (1994) in Regulation of Signal Transduction Pathways by Desensitization and Amplification (Sibley, D. R., and Houslay, M. D., eds) pp. 25-67, John Wiley & Sons, New York
4. DebBurman, S. K., and Hosey, M. M. (1995) in Molecular Mechanisms of Muscarinic Acetylcholine Receptor Function (Wess, J., ed) pp. 209-226, R. G. Landes Co., Austin, TX
5. Lefkowitz, R. J. (1993) Cell 74, 409-412
6. Benovic, J. L., Strasser, R. H., Caron, M. G., and Lefkowitz, R. J. (1986) Proc. Natl. Acad. Sci. U. S. A. 83, 2797-2801
7. Benovic, J. L., Mayor, F., Jr., Staniszewski, C., Lefkowitz, R. J., and Caron, M. G. (1987) J. Biol. Chem. 262, 9026-9032
8. Kwatra, M. M., Benovic, J. L., Caron, M. G., Lefkowitz, R. J., and Hosey, M. M. (1989) Biochemistry 28, 4543-4547
9. Kwatra, M. M., Schwinn, D. A., Schreurs, J., Blank, J. L., Kim, C. M., Benovic, J. L., Krause, J. E., Caron, M. G., and Lefkowitz, R. J. (1993) J. Biol. Chem. 268, 9161-9164
10. Pippig, S., Andexinger, S., Daniel, K., Puzicha, M., Caron, M. G., Lefkowitz, R. J., and Lohse, M. J. (1993) J. Biol. Chem. 268, 3201-3208
11. Lohse, M. J., Lefkowitz, R. J., Caron, M. G., and Benovic, J. L. (1989) Proc. Natl. Acad. Sci. U. S. A. 86, 3011-301
12. Lohse, M. J., Benovic, J. L., Caron, M. G., and Lefkowitz, R. J. (1990) J. Biol. Chem. 265, 3202-3209
13. Liggett, S. B., Ostrowski, J., Chestnut, L. C., Kurose, H., Raymond, J. R., Caron, M. G., and Lefkowitz, R. J. (1992) J. Biol. Chem. 267, 4740-4746
14. Eason, M. G., Moreira, S. P., and Liggett, S. B. (1995) J. Biol. Chem. 270, 4681-4688
15. Pals-Rylaarsdam, R., Xu., Y., Witt-Enderby, P., Benovic, J. L., and Hosey, M. M. (1995) J. Biol. Chem. 270, 29004-29011
16. Shih, M., and Malbon, C. C. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 12193-12197
17. Kong, G., Penn, R., and Benovic, J. L. (1994) J. Biol. Chem. 269, 13084-13087
18. Tsuga, H., Kameyama, K., Haga, T., Kurose, H., and Nagao, T. (1994) J. Biol. Chem. 269, 32522-32527
19. Koch, W. J., Rockman, H. A., Samana, P., Hamilton, R., Bond, R. A., Milano, C. A., and Lefkowitz, R. J. (1995) Science 268, 1350-1353
20. Benovic, J. L., DeBlasi, A., Stone, W. C., Caron, M. G., and Lefkowitz, R. J. (1989) Science 246, 235-240
21. Benovic, J. L., Onorato, J. J., Arriza, J. L., Stone, W. C., Lohse, M., Jenkins, N. A., Gilbert, D. J., Copeland, N. G., Caron, M. G., and Lefkowitz, R. J. (1991) J. Biol. Chem. 266, 14939-14946
22. Lorenz, W., Inglese, J., Palczewski, K., Onorato, J. J., Caron, M. G., and Lefkowitz, R. J. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 8715-8719
23. Ambrose, C., James, M., Barnes, G., Lin, C., Bates, G., Althen, M., Duyao, M., Groot, N., Church, D., Wasmuth, J. J., Lehrach, H., Housman, D., Buckler, A., Gusella, J. F., and MacDonald, M. E. (1993) Hum. Mol. Genet. 1, 697-703
24. Kunapuli, P., and Benovic, J. L. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 5588-5592
25. Benovic, J. L., and Gomez, J. (1993) J. Biol. Chem. 268, 19521-19527
26. Haga, K., and Haga, T. (1990) FEBS Lett. 268, 43-47
27. Haga, K., and Haga, T. (1992) J. Biol. Chem. 267, 2222-2227
28. Pitcher, J. A., Inglese, J., Higgins, J. B., Arriza, J. L., Casey, P. J., Kim, C., Benovic, J. L., Kwatra, M. M., Caron, M. G., and Lefkowitz, R. J. (1992) Science 257, 1264-1267
29. Kim, C. M., Dion, S. B., and Benovic, J. L. (1993) J. Biol. Chem. 268, 15412-15418
30. Kameyama, K., Haga, K., Haga, T., Kontani, K., Katada, T., and Fukada, Y. (1993) J. Biol. Chem. 268, 7753-7758
31. Chen, C.-Y., Dion, S. B., Kim, C. M., and Benovic, J. L. (1993) J. Biol. Chem. 268, 7825-7831
32. Ren, Q., Kurose, H., Lefkowitz, R. J., and Cottechia, S. (1993) J. Biol. Chem. 268, 16483-16487
33. Haga, K., Kameyama, K., and Haga, T. (1994) J. Biol. Chem. 269, 12594-12599
34. Richardson, R. M., Kim, C., Benovic, J. L., and Hosey, M. M. (1993) J. Biol. Chem. 268, 13650-13656
35. Kameyama, K., Haga, K., Haga, T., Moro, O., and Sadee, W. (1994) Eur. J. Biochem. 226, 267-276
36. Palczewski, K., Buczylko, J., Kaplan, M. W., Polans, A. W., and Crabb, J. W. (1991) J. Biol. Chem. 266, 12949-12955
37. Palczewski, K., Buczylko, J., Lebioda, L., Crabb, J. W., and Polans, A. S. (1993) J. Biol. Chem. 268, 6004-6013
38. Shi, W., Osawa, S., Dickerson, C. D., and Weiss, E. R. (1995) J. Biol. Chem. 270, 2112-2119
39. Koch, W. J., Inglese, J., Stone, W. C., and Lefkowitz, R. J. (1993) J. Biol. Chem. 268, 8256-8260
40. Inglese, J., Freedman, N. J., Koch, W. J., and Lefkowitz, R. J. (1993) J. Biol. Chem. 268, 23735-23738
41. Haslam, R. J., Koide, H. B., and Hemmings, B. A. (1993) Nature 363, 309-310
42. Mayer, B. J., Ren, R., Clark, K. L., and Baltimore, D. (1993) Cell 73, 629-630
43. Musacchio, A., Gibson, T., Rice, P., Thompson, J., and Saraste, M. (1993) Trends Biochem. 18, 343-347
44. Gibson, T. J., Hyvonen, M., Mussachio, A., Saraste, M., and Birney, E. (1994) Trends Biochem. 19, 349-353
45. Harlan, J. E., Hajduk, P. J., Yoon, H. S., and Fesik, S. W. (1994) Nature 371, 168-170
46. Harlan, J. E., Yoon, H. S., Hajduk, P. J., and Fesik, S. W. (1995) Biochemistry 34, 9859-9864
47. Touhara, K., Koch, W. J., Hawes, B. E., and Lefkowitz, R. J. (1995) J. Biol. Chem. 270, 17000-17005
48. Ferguson, K. M., Lemmon, M. A., Schlessinger, J., and Sigler, P. B. (1995b) Cell 83, 1037-1046
49. Hyvonen, M., Macias, M. J., Nilges, M., Oschkinat, H., Saraste, M., and Wilmanns, M. (1995) EMBO J. 14, 4676-4685
50. Lemmon, M. A., Ferguson, K. M., O'Brien, R., Sigler, P. B., and Schlessinger, J. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 10472-10476
51. Tsukada, S., Simon, M. I., Witte, O. N., and Katz, A. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 11256-11260
52. Touhara, K., Inglese, J., Pitcher, J. A., Shaw, G., and Lefkowitz, R. J. (1994) J. Biol. Chem. 269, 10217-10220
53. Langhans-Rajasekaran, S. A., Wan, Y., and Huang, X.-Y. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 8601-8605
54. Mahadevan, D., Thanki, N., Singh, J., McPhie, P., Zangrelli, D., Wang, L-M., Guerrero, C., Levine, H., Humblet, C., Saldanha, J., Gutkind, S. J., and Najmabadi-Haske, T. (1995) Biochemistry 34, 9111-9117
55. Yao, L., Kawakami, Y., and Kawakami, T. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 9175-9179
56. DebBurman, S. K., Ptasienski, J., Boetticher, E., Lomasney, J. W., Benovic, J. L., and Hosey, M. M. (1995) J. Biol. Chem. 270, 5742-5747
57. Onorato, J. J., Gillis, M. E., Liu, Y., Benovic, J. L., and Ruoho, A. E. (1995) J. Biol. Chem. 270, 21346-21353
58. Pitcher, J. A., Touhara, K., Payne, E. S., and Lefkowitz, R. J. (1995) J. Biol. Chem. 270, 11707-11710
59. DebBurman, S. K., Kunapuli, P., Benovic, J. L., and Hosey, M. M. (1995b) Mol. Pharmacol. 47, 224-233
60. O'Reilly, D. R., Miller, L. K., and Luckow, Y. A. (1992) Baculovirus Expression Vectors, W. H. Freeman, New York
61. Kim, C. M., Dion, S. B., Onorato, J. J., and Benovic, J. L. (1993) J. Recept. Res. 3, 39-55
62. Laemmli, U. K. (1970) Nature 227, 680-685
63. Peterson, G. L., Toumadje, A., Johnson, W. C., Jr., and Schimerlik, M. I. (1995) J. Biol. Chem. 270, 17808-17814
64. Shichi, H., and Somers, R. L. (1978) J. Biol. Chem. 253, 7040-7046
65. Saraste, M., and Hyvonen, M. (1995) Curr. Opin. Struct. Biol. 5, 403-408
66. Xu, R. M., Carmel, G., Sweet, R. M., Kuret, J., and Cheng, X. (1995) Proc. Natl. Acad. Sci. U. S. A. 14, 1015-1023
67. Divecha, D., and R. F. Levine. (1995) Cell 80, 269-278
68. Liscovitch, M., and Cantley, L. C. (1994) Cell 77, 329-334
69. Garcia-Higuera, I., Penela, P., Murga, C., Egea, G., Bonay, P., Benovic, J. L., and Mayor, F., Jr. (1994) J. Biol. Chem. 269, 1348-1355
70. Murga, C., Ruiz-Gomez, A., Garcia-Higuera, Kim, C. M., Benovic, J. L., and Mayor, F., Jr. (1996) J. Biol. Chem. 271, 985-994
71. Koch, W. J., Hawes, B. E., Inglese, J., Lutrell, L. M., and Lefkowitz, R. J. (1994) J. Biol. Chem. 269, 6193-6197
72. Pawson, T. (1994) Nature 373, 573-580
73. McCollam, L., Bonfini, L., Karlovich, C. A., Conway, B. R., Kozma, L. M., Banerjee, U., and Czech, M. P. (1995) J. Biol. Chem. 270, 15954-15957
74. Newton, A. C. (1995) J. Biol. Chem. 270, 28495-28498
75. Kunapuli, P., Gurevich, V. V., and Benovic, J. L. (1994) J. Biol. Chem. 269, 10209-10212
76. Brockman, J. L., and Anderson, R. A. (1991) J. Biol. Chem. 266, 2508-2512
77. Stoffel, R. H., Randall, R. R., Premont, R. T., Lefkowitz, R. J., and Inglese, J. (1994) J. Biol. Chem. 269, 27791-27794
78. Premont, R. T., Macrae, A. D., Stoffel, R. H., Chung, N., Pitcher, J. A., Ambrose, C., Inglese, J., MacDonald, M. E., and Lefkowitz, R. J. (1996) J. Biol. Chem. 271, 6403-6410
79. Quinn, P. J. (1976) The Molecular Biology of Cell Membranes, p. 33, University Park Press, Baltimore