메뉴 건너뛰기




Volumn 1, Issue , 2014, Pages 489-511

Bioavailability of Flavonoids: The Role of Cell Membrane Transporters

Author keywords

Bioavailability; Flavonoids; Membrane transport; Polyphenols; Xenobiotic transporters

Indexed keywords


EID: 84902570798     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-12-398456-2.00037-2     Document Type: Chapter
Times cited : (42)

References (266)
  • 1
    • 13844271387 scopus 로고    scopus 로고
    • Bioavailability and bioefficacy of polyphenols in humans. II. Review of 93 intervention studies
    • Williamson G., Manach C. Bioavailability and bioefficacy of polyphenols in humans. II. Review of 93 intervention studies. Am J Clin Nutr 2005, 81(1):243S-255S.
    • (2005) Am J Clin Nutr , vol.81 , Issue.1
    • Williamson, G.1    Manach, C.2
  • 2
    • 84877152770 scopus 로고    scopus 로고
    • Pleiotropic preventive effects of dietary polyphenols in cardiovascular diseases
    • Kishimoto Y., Tani M., Kondo K. Pleiotropic preventive effects of dietary polyphenols in cardiovascular diseases. Eur J Clin Nutr 2013, 67(5):532-535.
    • (2013) Eur J Clin Nutr , vol.67 , Issue.5 , pp. 532-535
    • Kishimoto, Y.1    Tani, M.2    Kondo, K.3
  • 3
    • 0036849077 scopus 로고    scopus 로고
    • The biochemistry and medical significance of the flavonoids
    • Havsteen B.H. The biochemistry and medical significance of the flavonoids. Pharmacol Ther 2002, 96(2-3):67-202.
    • (2002) Pharmacol Ther , vol.96 , Issue.2-3 , pp. 67-202
    • Havsteen, B.H.1
  • 4
    • 0035289779 scopus 로고    scopus 로고
    • Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
    • Lipinski C., Lombardo F., Dominy B., Feeney P. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv Drug Deliv Rev 2001, 46(1-3):3-26.
    • (2001) Adv Drug Deliv Rev , vol.46 , Issue.1-3 , pp. 3-26
    • Lipinski, C.1    Lombardo, F.2    Dominy, B.3    Feeney, P.4
  • 5
    • 24344439264 scopus 로고    scopus 로고
    • Transporters and drug therapy: implications for drug disposition and disease
    • Ho R.H., Kim R.B. Transporters and drug therapy: implications for drug disposition and disease. Clin Pharmacol Ther 2005, 78(3):260-277.
    • (2005) Clin Pharmacol Ther , vol.78 , Issue.3 , pp. 260-277
    • Ho, R.H.1    Kim, R.B.2
  • 6
    • 40049110714 scopus 로고    scopus 로고
    • Carrier-mediated cellular uptake of pharmaceutical drugs: an exception or the rule?
    • Dobson P.D., Kell D.B. Carrier-mediated cellular uptake of pharmaceutical drugs: an exception or the rule?. Nat Rev Drug Discov 2008, 7(3):205-220.
    • (2008) Nat Rev Drug Discov , vol.7 , Issue.3 , pp. 205-220
    • Dobson, P.D.1    Kell, D.B.2
  • 7
    • 80051666394 scopus 로고    scopus 로고
    • Pharmaceutical drug transport: the issues and the implications that it is essentially carrier-mediated only
    • Kell D.B., Dobson P.D., Oliver S.G. Pharmaceutical drug transport: the issues and the implications that it is essentially carrier-mediated only. Drug Discov Today 2011, 16(15-16):704-714.
    • (2011) Drug Discov Today , vol.16 , Issue.15-16 , pp. 704-714
    • Kell, D.B.1    Dobson, P.D.2    Oliver, S.G.3
  • 8
    • 33644873454 scopus 로고    scopus 로고
    • TCDB: the transporter classification database for membrane transport protein analyses and information
    • Database Issue
    • Saier M.H., Tran C.V., Barabote R.D. TCDB: the transporter classification database for membrane transport protein analyses and information. Nucleic Acids Res 2006, 34(Database issue):D181-86.
    • (2006) Nucleic Acids Res , vol.34
    • Saier, M.H.1    Tran, C.V.2    Barabote, R.D.3
  • 9
    • 75149162948 scopus 로고    scopus 로고
    • TransportTP: a two-phase classification approach for membrane transporter prediction and characterization
    • Li H., Benedito V.A., Udvardi M.K., Zhao P.X. TransportTP: a two-phase classification approach for membrane transporter prediction and characterization. BMC Bioinformatics 2009, 10:418.
    • (2009) BMC Bioinformatics , vol.10 , pp. 418
    • Li, H.1    Benedito, V.A.2    Udvardi, M.K.3    Zhao, P.X.4
  • 10
    • 58149202169 scopus 로고    scopus 로고
    • The transporter classification database: recent advances
    • (Database issue)
    • Saier M.H., Yen M.R., Noto K., Tamang D.G., Elkan C. The transporter classification database: recent advances. Nucleic Acids Res 2009, 37:274-278. (Database issue).
    • (2009) Nucleic Acids Res , vol.37 , pp. 274-278
    • Saier, M.H.1    Yen, M.R.2    Noto, K.3    Tamang, D.G.4    Elkan, C.5
  • 11
    • 0037457802 scopus 로고    scopus 로고
    • Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview
    • Schinkel A.H., Jonker J.W. Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview. Adv Drug Deliv Rev 2003, 55(1):3-29.
    • (2003) Adv Drug Deliv Rev , vol.55 , Issue.1 , pp. 3-29
    • Schinkel, A.H.1    Jonker, J.W.2
  • 12
    • 43149118341 scopus 로고    scopus 로고
    • The role of ABC transporters in drug absorption, distribution, metabolism, excretion and toxicity (ADME-Tox)
    • Szakacs G., Varadi A., Ozvegy-Laczka C., Sarkadi B. The role of ABC transporters in drug absorption, distribution, metabolism, excretion and toxicity (ADME-Tox). Drug Discov Today 2008, 13(9-10):379-393.
    • (2008) Drug Discov Today , vol.13 , Issue.9-10 , pp. 379-393
    • Szakacs, G.1    Varadi, A.2    Ozvegy-Laczka, C.3    Sarkadi, B.4
  • 13
    • 1242340323 scopus 로고    scopus 로고
    • The ABCs of solute carriers: physiological, pathological and therapeutic implications of human membrane transport proteins. Introduction
    • Hediger M.A., Romero M.F., Peng J.B., Rolfs A., Takanaga H., Bruford E.A. The ABCs of solute carriers: physiological, pathological and therapeutic implications of human membrane transport proteins. Introduction. Pflugers Arch 2004, 447(5):465-468.
    • (2004) Pflugers Arch , vol.447 , Issue.5 , pp. 465-468
    • Hediger, M.A.1    Romero, M.F.2    Peng, J.B.3    Rolfs, A.4    Takanaga, H.5    Bruford, E.A.6
  • 14
    • 84954358022 scopus 로고    scopus 로고
    • The solute carrier (SLC) complement of the human genome: phylogenetic classification reveals four major families
    • Fredriksson R., Nordstrom K.J., Stephansson O., Hagglund M.G., Schioth H.B. The solute carrier (SLC) complement of the human genome: phylogenetic classification reveals four major families. FEBS Lett 2008, 582(27):3811-3816.
    • (2008) FEBS Lett , vol.582 , Issue.27 , pp. 3811-3816
    • Fredriksson, R.1    Nordstrom, K.J.2    Stephansson, O.3    Hagglund, M.G.4    Schioth, H.B.5
  • 16
    • 0032568838 scopus 로고    scopus 로고
    • Identification of glutathione as a driving force and leukotriene C4 as a substrate for oatp1, the hepatic sinusoidal organic solute transporter
    • Li L., Lee T.K., Meier P.J., Ballatori N. Identification of glutathione as a driving force and leukotriene C4 as a substrate for oatp1, the hepatic sinusoidal organic solute transporter. J Biol Chem 1998, 273(26):16184-16191.
    • (1998) J Biol Chem , vol.273 , Issue.26 , pp. 16184-16191
    • Li, L.1    Lee, T.K.2    Meier, P.J.3    Ballatori, N.4
  • 17
    • 34547104864 scopus 로고    scopus 로고
    • Human organic anion transporter 1B1 and 1B3 function as bidirectional carriers and do not mediate GSH-bile acid cotransport
    • Mahagita C., Grassl S.M., Piyachaturawat P., Ballatori N. Human organic anion transporter 1B1 and 1B3 function as bidirectional carriers and do not mediate GSH-bile acid cotransport. Am J Physiol Gastrointest Liver Physiol 2007, 293(1):G271-278.
    • (2007) Am J Physiol Gastrointest Liver Physiol , vol.293 , Issue.1
    • Mahagita, C.1    Grassl, S.M.2    Piyachaturawat, P.3    Ballatori, N.4
  • 18
    • 13744263546 scopus 로고    scopus 로고
    • Regulation of organic cation transport
    • Ciarimboli G., Schlatter E. Regulation of organic cation transport. Pflugers Arch 2005, 449(5):423-441.
    • (2005) Pflugers Arch , vol.449 , Issue.5 , pp. 423-441
    • Ciarimboli, G.1    Schlatter, E.2
  • 19
    • 48749084010 scopus 로고    scopus 로고
    • Structure, and regulation of the cloned organic anion transporters
    • Srimaroeng C., Perry J.L., Physiology Pritchard J.B. structure, and regulation of the cloned organic anion transporters. Xenobiotica 2008, 38(7-8):889-935.
    • (2008) Xenobiotica , vol.38 , Issue.7-8 , pp. 889-935
    • Srimaroeng, C.1    Perry, J.L.2    Physiology, P.J.B.3
  • 20
    • 68349144331 scopus 로고    scopus 로고
    • Bioavailability of flavonoids: a review of their membrane transport and the function of bilitranslocase in animal and plant organisms
    • Passamonti S., Terdoslavich M., Franca R., Vanzo A., Tramer F., Braidot E., et al. Bioavailability of flavonoids: a review of their membrane transport and the function of bilitranslocase in animal and plant organisms. Curr Drug Metab 2009, 10(4):369-394.
    • (2009) Curr Drug Metab , vol.10 , Issue.4 , pp. 369-394
    • Passamonti, S.1    Terdoslavich, M.2    Franca, R.3    Vanzo, A.4    Tramer, F.5    Braidot, E.6
  • 21
    • 33748891217 scopus 로고    scopus 로고
    • Bioavailability and tissue distribution of anthocyanins in bilberry (Vaccinium myrtillus L.) extract in rats
    • Ichiyanagi T., Shida Y., Rahman M.M., Hatano Y., Konishi T. Bioavailability and tissue distribution of anthocyanins in bilberry (Vaccinium myrtillus L.) extract in rats. J Agric Food Chem 2006, 54(18):6578-6587.
    • (2006) J Agric Food Chem , vol.54 , Issue.18 , pp. 6578-6587
    • Ichiyanagi, T.1    Shida, Y.2    Rahman, M.M.3    Hatano, Y.4    Konishi, T.5
  • 22
    • 0036830231 scopus 로고    scopus 로고
    • Safety and pharmacokinetics of purified soy isoflavones: single-dose administration to postmenopausal women
    • Bloedon L.T., Jeffcoat A.R., Lopaczynski W., Schell M.J., Black T.M., Dix K.J., et al. Safety and pharmacokinetics of purified soy isoflavones: single-dose administration to postmenopausal women. Am J Clin Nutr 2002, 76(5):1126-1137.
    • (2002) Am J Clin Nutr , vol.76 , Issue.5 , pp. 1126-1137
    • Bloedon, L.T.1    Jeffcoat, A.R.2    Lopaczynski, W.3    Schell, M.J.4    Black, T.M.5    Dix, K.J.6
  • 24
    • 33644523075 scopus 로고    scopus 로고
    • Ingested delphinidin-3-rutinoside is primarily excreted to urine as the intact form and to bile as the methylated form in rats
    • Matsumoto H., Ichiyanagi T., Iida H., Ito K., Tsuda T., Hirayama M., et al. Ingested delphinidin-3-rutinoside is primarily excreted to urine as the intact form and to bile as the methylated form in rats. J Agric Food Chem 2006, 54(2):578-582.
    • (2006) J Agric Food Chem , vol.54 , Issue.2 , pp. 578-582
    • Matsumoto, H.1    Ichiyanagi, T.2    Iida, H.3    Ito, K.4    Tsuda, T.5    Hirayama, M.6
  • 25
    • 77952633189 scopus 로고    scopus 로고
    • Anthocyanins are bioavailable in humans following an acute dose of cranberry juice
    • Milbury P.E., Vita J.A., Blumberg J.B. Anthocyanins are bioavailable in humans following an acute dose of cranberry juice. J Nutr 2010, 140(6):1099-1104.
    • (2010) J Nutr , vol.140 , Issue.6 , pp. 1099-1104
    • Milbury, P.E.1    Vita, J.A.2    Blumberg, J.B.3
  • 26
    • 23844534408 scopus 로고    scopus 로고
    • Plasma and urine responses are lower for acylated vs nonacylated anthocyanins from raw and cooked purple carrots
    • Kurilich A.C., Clevidence B.A., Britz S.J., Simon P.W., Novotny J.A. Plasma and urine responses are lower for acylated vs nonacylated anthocyanins from raw and cooked purple carrots. J Agric Food Chem 2005, 53(16):6537-6542.
    • (2005) J Agric Food Chem , vol.53 , Issue.16 , pp. 6537-6542
    • Kurilich, A.C.1    Clevidence, B.A.2    Britz, S.J.3    Simon, P.W.4    Novotny, J.A.5
  • 27
    • 26444585579 scopus 로고    scopus 로고
    • Aglycones and sugar moieties alter anthocyanin absorption and metabolism after berry consumption in weanling pigs
    • Wu X., Pittman H.E., McKay S., Prior R.L. Aglycones and sugar moieties alter anthocyanin absorption and metabolism after berry consumption in weanling pigs. J Nutr 2005, 135(10):2417-2424.
    • (2005) J Nutr , vol.135 , Issue.10 , pp. 2417-2424
    • Wu, X.1    Pittman, H.E.2    McKay, S.3    Prior, R.L.4
  • 28
    • 0032915558 scopus 로고    scopus 로고
    • Direct intestinal absorption of red fruit anthocyanins, cyanidin-3-glucoside and cyanidin-3,5-diglucoside, into rats and humans
    • Miyazawa T., Nakagawa K., Kudo M., Muraishi K., Someya K. Direct intestinal absorption of red fruit anthocyanins, cyanidin-3-glucoside and cyanidin-3,5-diglucoside, into rats and humans. J Agric Food Chem 1999, 47(3):1083-1091.
    • (1999) J Agric Food Chem , vol.47 , Issue.3 , pp. 1083-1091
    • Miyazawa, T.1    Nakagawa, K.2    Kudo, M.3    Muraishi, K.4    Someya, K.5
  • 29
    • 0037462059 scopus 로고    scopus 로고
    • Absorption and excretion of black currant anthocyanins in humans and watanabe heritable hyperlipidemic rabbits
    • Nielsen I.L., Dragsted L.O., Ravn-Haren G., Freese R., Rasmussen S.E. Absorption and excretion of black currant anthocyanins in humans and watanabe heritable hyperlipidemic rabbits. J Agric Food Chem 2003, 51(9):2813-2820.
    • (2003) J Agric Food Chem , vol.51 , Issue.9 , pp. 2813-2820
    • Nielsen, I.L.1    Dragsted, L.O.2    Ravn-Haren, G.3    Freese, R.4    Rasmussen, S.E.5
  • 31
    • 0037855692 scopus 로고    scopus 로고
    • Bioavailability of anthocyanidin-3-glucosides following consumption of red wine and red grape juice
    • Frank T., Netzel M., Strass G., Bitsch R., Bitsch I. Bioavailability of anthocyanidin-3-glucosides following consumption of red wine and red grape juice. Can J Physiol Pharmacol 2003, 81(5):423-435.
    • (2003) Can J Physiol Pharmacol , vol.81 , Issue.5 , pp. 423-435
    • Frank, T.1    Netzel, M.2    Strass, G.3    Bitsch, R.4    Bitsch, I.5
  • 32
    • 52649120818 scopus 로고    scopus 로고
    • Pharmacokinetics of anthocyanins and antioxidant effects after the consumption of anthocyanin-rich acai juice and pulp (Euterpe oleracea Mart.) in human healthy volunteers
    • Mertens-Talcott S.U., Rios J., Jilma-Stohlawetz P., Pacheco-Palencia L.A., Meibohm B., Talcott S.T., et al. Pharmacokinetics of anthocyanins and antioxidant effects after the consumption of anthocyanin-rich acai juice and pulp (Euterpe oleracea Mart.) in human healthy volunteers. J Agric Food Chem 2008, 56(17):7796-7802.
    • (2008) J Agric Food Chem , vol.56 , Issue.17 , pp. 7796-7802
    • Mertens-Talcott, S.U.1    Rios, J.2    Jilma-Stohlawetz, P.3    Pacheco-Palencia, L.A.4    Meibohm, B.5    Talcott, S.T.6
  • 33
    • 77955284662 scopus 로고    scopus 로고
    • Oral bioavailability of quercetin from different quercetin glycosides in dogs
    • Reinboth M., Wolffram S., Abraham G., Ungemach F.R., Cermak R. Oral bioavailability of quercetin from different quercetin glycosides in dogs. Br J Nutr 2010, 104(2):198-203.
    • (2010) Br J Nutr , vol.104 , Issue.2 , pp. 198-203
    • Reinboth, M.1    Wolffram, S.2    Abraham, G.3    Ungemach, F.R.4    Cermak, R.5
  • 34
    • 79955699885 scopus 로고    scopus 로고
    • Pharmacokinetic profile of total quercetin after single oral dose of tartary buckwheat extracts in rats
    • Zhao G., Zou L., Wang Z., Hu H., Hu Y., Peng L. Pharmacokinetic profile of total quercetin after single oral dose of tartary buckwheat extracts in rats. J Agric Food Chem 2011, 59(9):4435-4441.
    • (2011) J Agric Food Chem , vol.59 , Issue.9 , pp. 4435-4441
    • Zhao, G.1    Zou, L.2    Wang, Z.3    Hu, H.4    Hu, Y.5    Peng, L.6
  • 35
    • 0033661837 scopus 로고    scopus 로고
    • Pharmacokinetics of quercetin from quercetin aglycone and rutin in healthy volunteers
    • Erlund I., Kosonen T., Alfthan G., Maenpaa J., Perttunen K., Kenraali J., et al. Pharmacokinetics of quercetin from quercetin aglycone and rutin in healthy volunteers. Eur J Clin Pharmacol 2000, 56(8):545-553.
    • (2000) Eur J Clin Pharmacol , vol.56 , Issue.8 , pp. 545-553
    • Erlund, I.1    Kosonen, T.2    Alfthan, G.3    Maenpaa, J.4    Perttunen, K.5    Kenraali, J.6
  • 37
    • 0037462073 scopus 로고    scopus 로고
    • Absorption and urinary excretion of quercetin, rutin, and alphaG-rutin, a water soluble flavonoid, in rats
    • Shimoi K., Yoshizumi K., Kido T., Usui Y., Yumoto T. Absorption and urinary excretion of quercetin, rutin, and alphaG-rutin, a water soluble flavonoid, in rats. J Agric Food Chem 2003, 51(9):2785-2789.
    • (2003) J Agric Food Chem , vol.51 , Issue.9 , pp. 2785-2789
    • Shimoi, K.1    Yoshizumi, K.2    Kido, T.3    Usui, Y.4    Yumoto, T.5
  • 38
    • 84859891023 scopus 로고    scopus 로고
    • Pharmacokinetics of quercetin absorption from apples and onions in healthy humans
    • Lee J., Mitchell A.E. Pharmacokinetics of quercetin absorption from apples and onions in healthy humans. J Agric Food Chem 2012, 60(15):3874-3881.
    • (2012) J Agric Food Chem , vol.60 , Issue.15 , pp. 3874-3881
    • Lee, J.1    Mitchell, A.E.2
  • 39
    • 0034108013 scopus 로고    scopus 로고
    • Bioavailability and metabolism of the flavonol quercetin in the pig
    • Ader P., Wessmann A., Wolffram S. Bioavailability and metabolism of the flavonol quercetin in the pig. Free Radic Biol Med 2000, 28(7):1056-1067.
    • (2000) Free Radic Biol Med , vol.28 , Issue.7 , pp. 1056-1067
    • Ader, P.1    Wessmann, A.2    Wolffram, S.3
  • 40
    • 21244465966 scopus 로고    scopus 로고
    • Pharmacokinetics and modeling of quercetin and metabolites
    • Chen X., Yin O.Q., Zuo Z., Chow M.S. Pharmacokinetics and modeling of quercetin and metabolites. Pharm Res 2005, 22(6):892-901.
    • (2005) Pharm Res , vol.22 , Issue.6 , pp. 892-901
    • Chen, X.1    Yin, O.Q.2    Zuo, Z.3    Chow, M.S.4
  • 41
    • 12944296601 scopus 로고    scopus 로고
    • Investigation of the bioavailability of hypericin, pseudohypericin, hyperforin and the flavonoids quercetin and isorhamnetin following single and multiple oral dosing of a hypericum extract containing tablet
    • Schulz H.U., Schurer M., Bassler D., Weiser D. Investigation of the bioavailability of hypericin, pseudohypericin, hyperforin and the flavonoids quercetin and isorhamnetin following single and multiple oral dosing of a hypericum extract containing tablet. Arzneimittelforschung 2005, 55(1):15-22.
    • (2005) Arzneimittelforschung , vol.55 , Issue.1 , pp. 15-22
    • Schulz, H.U.1    Schurer, M.2    Bassler, D.3    Weiser, D.4
  • 42
  • 43
    • 14644414785 scopus 로고    scopus 로고
    • Simultaneous determination of luteolin and apigenin in dog plasma by RP-HPLC
    • Li L., Jiang H., Wu H., Zeng S. Simultaneous determination of luteolin and apigenin in dog plasma by RP-HPLC. J Pharm Biomed Anal 2005, 37(3):615-620.
    • (2005) J Pharm Biomed Anal , vol.37 , Issue.3 , pp. 615-620
    • Li, L.1    Jiang, H.2    Wu, H.3    Zeng, S.4
  • 44
    • 34047225839 scopus 로고    scopus 로고
    • Absorption and excretion of luteolin and apigenin in rats after oral administration of Chrysanthemum morifolium extract
    • Chen T., Li L.P., Lu X.Y., Jiang H.D., Zeng S. Absorption and excretion of luteolin and apigenin in rats after oral administration of Chrysanthemum morifolium extract. J Agric Food Chem 2007, 55(2):273-277.
    • (2007) J Agric Food Chem , vol.55 , Issue.2 , pp. 273-277
    • Chen, T.1    Li, L.P.2    Lu, X.Y.3    Jiang, H.D.4    Zeng, S.5
  • 45
    • 33744828685 scopus 로고    scopus 로고
    • Bioavailability of apigenin from apiin-rich parsley in humans
    • Meyer H., Bolarinwa A., Wolfram G., Linseisen J. Bioavailability of apigenin from apiin-rich parsley in humans. Ann Nutr Metab 2006, 50(3):167-172.
    • (2006) Ann Nutr Metab , vol.50 , Issue.3 , pp. 167-172
    • Meyer, H.1    Bolarinwa, A.2    Wolfram, G.3    Linseisen, J.4
  • 46
    • 33746093547 scopus 로고    scopus 로고
    • Pharmacokinetics and metabolism of the flavonoid scutellarin in humans after a single oral administration
    • Chen X., Cui L., Duan X., Ma B., Zhong D. Pharmacokinetics and metabolism of the flavonoid scutellarin in humans after a single oral administration. Drug Metab Dispos 2006, 34(8):1345-1352.
    • (2006) Drug Metab Dispos , vol.34 , Issue.8 , pp. 1345-1352
    • Chen, X.1    Cui, L.2    Duan, X.3    Ma, B.4    Zhong, D.5
  • 47
    • 0031738302 scopus 로고    scopus 로고
    • Intestinal absorption of luteolin and luteolin 7-O-beta-glucoside in rats and humans
    • Shimoi K., Okada H., Furugori M., Goda T., Takase S., Suzuki M., et al. Intestinal absorption of luteolin and luteolin 7-O-beta-glucoside in rats and humans. FEBS Lett 1998, 438(3):220-224.
    • (1998) FEBS Lett , vol.438 , Issue.3 , pp. 220-224
    • Shimoi, K.1    Okada, H.2    Furugori, M.3    Goda, T.4    Takase, S.5    Suzuki, M.6
  • 48
    • 12944324240 scopus 로고    scopus 로고
    • Bioavailability and pharmacokinetics of caffeoylquinic acids and flavonoids after oral administration of artichoke leaf extracts in humans
    • Wittemer S.M., Ploch M., Windeck T., Muller S.C., Drewelow B., Derendorf H., et al. Bioavailability and pharmacokinetics of caffeoylquinic acids and flavonoids after oral administration of artichoke leaf extracts in humans. Phytomedicine 2005, 12(1-2):28-38.
    • (2005) Phytomedicine , vol.12 , Issue.1-2 , pp. 28-38
    • Wittemer, S.M.1    Ploch, M.2    Windeck, T.3    Muller, S.C.4    Drewelow, B.5    Derendorf, H.6
  • 49
    • 19544384432 scopus 로고    scopus 로고
    • Validation of an HPLC method for the determination of scutellarin in rat plasma and its pharmacokinetics
    • Hao X., Cheng G., Sun J., Zou M., Yu J., Zhang S., et al. Validation of an HPLC method for the determination of scutellarin in rat plasma and its pharmacokinetics. J Pharm Biomed Anal 2005, 38(2):360-363.
    • (2005) J Pharm Biomed Anal , vol.38 , Issue.2 , pp. 360-363
    • Hao, X.1    Cheng, G.2    Sun, J.3    Zou, M.4    Yu, J.5    Zhang, S.6
  • 50
    • 11144278688 scopus 로고    scopus 로고
    • Pharmacokinetics and metabolism of apigenin in female and male rats after a single oral administration
    • Gradolatto A., Basly J.P., Berges R., Teyssier C., Chagnon M.C., Siess M.H., et al. Pharmacokinetics and metabolism of apigenin in female and male rats after a single oral administration. Drug Metab Dispos 2005, 33(1):49-54.
    • (2005) Drug Metab Dispos , vol.33 , Issue.1 , pp. 49-54
    • Gradolatto, A.1    Basly, J.P.2    Berges, R.3    Teyssier, C.4    Chagnon, M.C.5    Siess, M.H.6
  • 51
    • 27644442245 scopus 로고    scopus 로고
    • Absorption and enterohepatic circulation of baicalin in rats
    • Xing J., Chen X., Zhong D. Absorption and enterohepatic circulation of baicalin in rats. Life Sci 2005, 78(2):140-146.
    • (2005) Life Sci , vol.78 , Issue.2 , pp. 140-146
    • Xing, J.1    Chen, X.2    Zhong, D.3
  • 53
    • 0035150315 scopus 로고    scopus 로고
    • Plasma kinetics and urinary excretion of the flavanones naringenin and hesperetin in humans after ingestion of orange juice and grapefruit juice
    • Erlund I., Meririnne E., Alfthan G., Aro A. Plasma kinetics and urinary excretion of the flavanones naringenin and hesperetin in humans after ingestion of orange juice and grapefruit juice. J Nutr 2001, 131(2):235-241.
    • (2001) J Nutr , vol.131 , Issue.2 , pp. 235-241
    • Erlund, I.1    Meririnne, E.2    Alfthan, G.3    Aro, A.4
  • 54
    • 0037327340 scopus 로고    scopus 로고
    • Bioavailability in humans of the flavanones hesperidin and narirutin after the ingestion of two doses of orange juice
    • Manach C., Morand C., Gil-Izquierdo A., Bouteloup-Demange C., Remesy C. Bioavailability in humans of the flavanones hesperidin and narirutin after the ingestion of two doses of orange juice. Eur J Clin Nutr 2003, 57(2):235-242.
    • (2003) Eur J Clin Nutr , vol.57 , Issue.2 , pp. 235-242
    • Manach, C.1    Morand, C.2    Gil-Izquierdo, A.3    Bouteloup-Demange, C.4    Remesy, C.5
  • 55
    • 34247212317 scopus 로고    scopus 로고
    • Pharmacokinetics of the citrus flavanone aglycones hesperetin and naringenin after single oral administration in human subjects
    • Kanaze F.I., Bounartzi M.I., Georgarakis M., Niopas I. Pharmacokinetics of the citrus flavanone aglycones hesperetin and naringenin after single oral administration in human subjects. Eur J Clin Nutr 2007, 61(4):472-477.
    • (2007) Eur J Clin Nutr , vol.61 , Issue.4 , pp. 472-477
    • Kanaze, F.I.1    Bounartzi, M.I.2    Georgarakis, M.3    Niopas, I.4
  • 56
    • 0036846041 scopus 로고    scopus 로고
    • Naringenin from cooked tomato paste is bioavailable in men
    • Bugianesi R., Catasta G., Spigno P., D'Uva A., Maiani G. Naringenin from cooked tomato paste is bioavailable in men. J Nutr 2002, 132(11):3349-3352.
    • (2002) J Nutr , vol.132 , Issue.11 , pp. 3349-3352
    • Bugianesi, R.1    Catasta, G.2    Spigno, P.3    D'Uva, A.4    Maiani, G.5
  • 57
    • 0242341414 scopus 로고    scopus 로고
    • Pharmacokinetics of (-)-epicatechin-3-O-gallate, an active component of Onpi-to, in rats
    • Takizawa Y., Morota T., Takeda S., Aburada M. Pharmacokinetics of (-)-epicatechin-3-O-gallate, an active component of Onpi-to, in rats. Biol Pharm Bull 2003, 26(5):608-612.
    • (2003) Biol Pharm Bull , vol.26 , Issue.5 , pp. 608-612
    • Takizawa, Y.1    Morota, T.2    Takeda, S.3    Aburada, M.4
  • 58
    • 16544394714 scopus 로고    scopus 로고
    • Bioavailability and antioxidant activity of tea flavanols after consumption of green tea, black tea, or a green tea extract supplement
    • Henning S.M., Niu Y., Lee N.H., Thames G.D., Minutti R.R., Wang H., et al. Bioavailability and antioxidant activity of tea flavanols after consumption of green tea, black tea, or a green tea extract supplement. Am J Clin Nutr 2004, 80(6):1558-1564.
    • (2004) Am J Clin Nutr , vol.80 , Issue.6 , pp. 1558-1564
    • Henning, S.M.1    Niu, Y.2    Lee, N.H.3    Thames, G.D.4    Minutti, R.R.5    Wang, H.6
  • 59
    • 20444480574 scopus 로고    scopus 로고
    • Effects of dosing condition on the oral bioavailability of green tea catechins after single-dose administration of Polyphenon E in healthy individuals
    • Chow H.H., Hakim I.A., Vining D.R., Crowell J.A., Ranger-Moore J., Chew W.M., et al. Effects of dosing condition on the oral bioavailability of green tea catechins after single-dose administration of Polyphenon E in healthy individuals. Clin Cancer Res 2005, 11(12):4627-4633.
    • (2005) Clin Cancer Res , vol.11 , Issue.12 , pp. 4627-4633
    • Chow, H.H.1    Hakim, I.A.2    Vining, D.R.3    Crowell, J.A.4    Ranger-Moore, J.5    Chew, W.M.6
  • 61
    • 0042334847 scopus 로고    scopus 로고
    • Pharmacokinetics and safety of green tea polyphenols after multiple-dose administration of epigallocatechin gallate and polyphenon E in healthy individuals
    • Chow H.H., Cai Y., Hakim I.A., Crowell J.A., Shahi F., Brooks C.A., et al. Pharmacokinetics and safety of green tea polyphenols after multiple-dose administration of epigallocatechin gallate and polyphenon E in healthy individuals. Clin Cancer Res 2003, 9(9):3312-3319.
    • (2003) Clin Cancer Res , vol.9 , Issue.9 , pp. 3312-3319
    • Chow, H.H.1    Cai, Y.2    Hakim, I.A.3    Crowell, J.A.4    Shahi, F.5    Brooks, C.A.6
  • 62
    • 0030763576 scopus 로고    scopus 로고
    • Absorption, distribution, elimination of tea polyphenols in rats
    • Chen L., Lee M.J., Li H., Yang C.S. Absorption, distribution, elimination of tea polyphenols in rats. Drug Metab Dispos 1997, 25(9):1045-1050.
    • (1997) Drug Metab Dispos , vol.25 , Issue.9 , pp. 1045-1050
    • Chen, L.1    Lee, M.J.2    Li, H.3    Yang, C.S.4
  • 63
    • 1642527931 scopus 로고    scopus 로고
    • Delivery of tea polyphenols to the oral cavity by green tea leaves and black tea extract
    • Lee M.J., Lambert J.D., Prabhu S., Meng X., Lu H., Maliakal P., et al. Delivery of tea polyphenols to the oral cavity by green tea leaves and black tea extract. Cancer Epidemiol Biomarkers Prev 2004, 13(1):132-137.
    • (2004) Cancer Epidemiol Biomarkers Prev , vol.13 , Issue.1 , pp. 132-137
    • Lee, M.J.1    Lambert, J.D.2    Prabhu, S.3    Meng, X.4    Lu, H.5    Maliakal, P.6
  • 64
    • 0036968115 scopus 로고    scopus 로고
    • The relation between single/double or repeated tea catechin ingestions and plasma antioxidant activity in humans
    • Kimura M., Umegaki K., Kasuya Y., Sugisawa A., Higuchi M. The relation between single/double or repeated tea catechin ingestions and plasma antioxidant activity in humans. Eur J Clin Nutr 2002, 56(12):1186-1193.
    • (2002) Eur J Clin Nutr , vol.56 , Issue.12 , pp. 1186-1193
    • Kimura, M.1    Umegaki, K.2    Kasuya, Y.3    Sugisawa, A.4    Higuchi, M.5
  • 65
    • 0034654655 scopus 로고    scopus 로고
    • 14C]Genistein in the rat: gender-related differences, potential mechanisms of biological action, and implications for human health
    • 14C]Genistein in the rat: gender-related differences, potential mechanisms of biological action, and implications for human health. Toxicol Appl Pharmacol 2000, 164(2):206-215.
    • (2000) Toxicol Appl Pharmacol , vol.164 , Issue.2 , pp. 206-215
    • Coldham, N.G.1    Sauer, M.J.2
  • 66
    • 0033936149 scopus 로고    scopus 로고
    • Soy isoflavone conjugation differs in fed and food-deprived rats
    • Piskula M.K. Soy isoflavone conjugation differs in fed and food-deprived rats. J Nutr 2000, 130(7):1766-1771.
    • (2000) J Nutr , vol.130 , Issue.7 , pp. 1766-1771
    • Piskula, M.K.1
  • 67
    • 0033949949 scopus 로고    scopus 로고
    • Soy isoflavone aglycones are absorbed faster and in higher amounts than their glucosides in humans
    • Izumi T., Piskula M.K., Osawa S., Obata A., Tobe K., Saito M., et al. Soy isoflavone aglycones are absorbed faster and in higher amounts than their glucosides in humans. J Nutr 2000, 130(7):1695-1699.
    • (2000) J Nutr , vol.130 , Issue.7 , pp. 1695-1699
    • Izumi, T.1    Piskula, M.K.2    Osawa, S.3    Obata, A.4    Tobe, K.5    Saito, M.6
  • 68
    • 33745660816 scopus 로고    scopus 로고
    • Preliminary investigation into the absorption of genistein and daidzein by domestic cats (Felis catus)
    • Bell K.M., Pearce P.D., Ugarte C.E., Hendriks W.H. Preliminary investigation into the absorption of genistein and daidzein by domestic cats (Felis catus). J Nutr 2006, 136(Suppl. 7):2004-2006.
    • (2006) J Nutr , vol.136 , Issue.SUPPL. 7 , pp. 2004-2006
    • Bell, K.M.1    Pearce, P.D.2    Ugarte, C.E.3    Hendriks, W.H.4
  • 69
    • 0036721557 scopus 로고    scopus 로고
    • Pharmacokinetics of the glucuronide and sulfate conjugates of genistein and daidzein in men and women after consumption of a soy beverage
    • Shelnutt S.R., Cimino C.O., Wiggins P.A., Ronis M.J., Badger T.M. Pharmacokinetics of the glucuronide and sulfate conjugates of genistein and daidzein in men and women after consumption of a soy beverage. Am J Clin Nutr 2002, 76(3):588-594.
    • (2002) Am J Clin Nutr , vol.76 , Issue.3 , pp. 588-594
    • Shelnutt, S.R.1    Cimino, C.O.2    Wiggins, P.A.3    Ronis, M.J.4    Badger, T.M.5
  • 70
    • 0037383299 scopus 로고    scopus 로고
    • Bioavailability, disposition, and dose-response effects of soy isoflavones when consumed by healthy women at physiologically typical dietary intakes
    • Setchell K.D., Brown N.M., Desai P.B., Zimmer-Nechimias L., Wolfe B., Jakate A.S., et al. Bioavailability, disposition, and dose-response effects of soy isoflavones when consumed by healthy women at physiologically typical dietary intakes. J Nutr 2003, 133(4):1027-1035.
    • (2003) J Nutr , vol.133 , Issue.4 , pp. 1027-1035
    • Setchell, K.D.1    Brown, N.M.2    Desai, P.B.3    Zimmer-Nechimias, L.4    Wolfe, B.5    Jakate, A.S.6
  • 71
    • 34347400398 scopus 로고    scopus 로고
    • The bioavailability and disposition kinetics of genistein in cats
    • Cave N.J., Backus R.C., Marks S.L., Klasing K.C. The bioavailability and disposition kinetics of genistein in cats. J Vet Pharmacol Ther 2007, 30(4):327-335.
    • (2007) J Vet Pharmacol Ther , vol.30 , Issue.4 , pp. 327-335
    • Cave, N.J.1    Backus, R.C.2    Marks, S.L.3    Klasing, K.C.4
  • 72
    • 58249119578 scopus 로고    scopus 로고
    • Studies of intestinal permeability of 36 flavonoids using Caco-2 cell monolayer model
    • Tian X.J., Yang X.W., Yang X., Wang K. Studies of intestinal permeability of 36 flavonoids using Caco-2 cell monolayer model. Int J Pharm 2009, 367(1-2):58-64.
    • (2009) Int J Pharm , vol.367 , Issue.1-2 , pp. 58-64
    • Tian, X.J.1    Yang, X.W.2    Yang, X.3    Wang, K.4
  • 74
    • 0345168969 scopus 로고    scopus 로고
    • Anthocyanins are efficiently absorbed from the stomach in anesthetized rats
    • Talavera S., Felgines C., Texier O., Besson C., Lamaison J., Remesy C. Anthocyanins are efficiently absorbed from the stomach in anesthetized rats. J Nutr 2003, 133(12):4178-4182.
    • (2003) J Nutr , vol.133 , Issue.12 , pp. 4178-4182
    • Talavera, S.1    Felgines, C.2    Texier, O.3    Besson, C.4    Lamaison, J.5    Remesy, C.6
  • 75
    • 84856694647 scopus 로고    scopus 로고
    • Anthocyanin kinetics are dependent on anthocyanin structure
    • Novotny J.A., Clevidence B.A., Kurilich A.C. Anthocyanin kinetics are dependent on anthocyanin structure. Br J Nutr 2012, 107(4):504-509.
    • (2012) Br J Nutr , vol.107 , Issue.4 , pp. 504-509
    • Novotny, J.A.1    Clevidence, B.A.2    Kurilich, A.C.3
  • 76
    • 0033048388 scopus 로고    scopus 로고
    • Daidzein and genistein but not their glucosides are absorbed from the rat stomach
    • Piskula M.K., Yamakoshi J., Iwai Y. Daidzein and genistein but not their glucosides are absorbed from the rat stomach. FEBS Lett 1999, 447(2-3):287-291.
    • (1999) FEBS Lett , vol.447 , Issue.2-3 , pp. 287-291
    • Piskula, M.K.1    Yamakoshi, J.2    Iwai, Y.3
  • 77
    • 0034904141 scopus 로고    scopus 로고
    • Comparison of the intestinal absorption of quercetin, phloretin and their glucosides in rats
    • Crespy V., Morand C., Besson C., Manach C., Demigne C., Remesy C. Comparison of the intestinal absorption of quercetin, phloretin and their glucosides in rats. J Nutr 2001, 131(8):2109-2114.
    • (2001) J Nutr , vol.131 , Issue.8 , pp. 2109-2114
    • Crespy, V.1    Morand, C.2    Besson, C.3    Manach, C.4    Demigne, C.5    Remesy, C.6
  • 78
    • 84860538880 scopus 로고    scopus 로고
    • A new approach on the gastric absorption of anthocyanins
    • Fernandes I., de Freitas V., Reis C., Mateus N. A new approach on the gastric absorption of anthocyanins. Food Funct 2012, 3(5):508-516.
    • (2012) Food Funct , vol.3 , Issue.5 , pp. 508-516
    • Fernandes, I.1    de Freitas, V.2    Reis, C.3    Mateus, N.4
  • 79
    • 0034108013 scopus 로고    scopus 로고
    • Bioavailability and metabolism of the flavonol quercetin in the pig
    • Ader P., Wessmann A., Wolffram S. Bioavailability and metabolism of the flavonol quercetin in the pig. Free Radic Biol Med 2000, 28(7):1056-1067.
    • (2000) Free Radic Biol Med , vol.28 , Issue.7 , pp. 1056-1067
    • Ader, P.1    Wessmann, A.2    Wolffram, S.3
  • 80
    • 0141849078 scopus 로고    scopus 로고
    • Involvement of multidrug resistance-associated proteins in regulating cellular levels of (-)-epigallocatechin-3-gallate and its methyl metabolites
    • Hong J., Lambert J.D., Lee S.H., Sinko P.J., Yang C.S. Involvement of multidrug resistance-associated proteins in regulating cellular levels of (-)-epigallocatechin-3-gallate and its methyl metabolites. Biochem Biophys Res Commun 2003, 310(1):222-227.
    • (2003) Biochem Biophys Res Commun , vol.310 , Issue.1 , pp. 222-227
    • Hong, J.1    Lambert, J.D.2    Lee, S.H.3    Sinko, P.J.4    Yang, C.S.5
  • 81
    • 0037196568 scopus 로고    scopus 로고
    • Inhibition of the multidrug resistance P-glycoprotein activity by green tea polyphenols
    • Jodoin J., Demeule M., Beliveau R. Inhibition of the multidrug resistance P-glycoprotein activity by green tea polyphenols. Biochim Biophys Acta 2002, 1542(1-3):149-159.
    • (2002) Biochim Biophys Acta , vol.1542 , Issue.1-3 , pp. 149-159
    • Jodoin, J.1    Demeule, M.2    Beliveau, R.3
  • 83
    • 32844470293 scopus 로고    scopus 로고
    • Absorption, tissue distribution and excretion of pelargonidin and its metabolites following oral administration to rats
    • El Mohsen M., Marks J., Kuhnle G., Moore K., Debnam E., Kaila Srai S., et al. Absorption, tissue distribution and excretion of pelargonidin and its metabolites following oral administration to rats. Br J Nutr 2006, 95(1):51-58.
    • (2006) Br J Nutr , vol.95 , Issue.1 , pp. 51-58
    • El Mohsen, M.1    Marks, J.2    Kuhnle, G.3    Moore, K.4    Debnam, E.5    Kaila Srai, S.6
  • 85
    • 80052269348 scopus 로고    scopus 로고
    • Accumulation of orally administered quercetin in brain tissue and its antioxidative effects in rats
    • Ishisaka A., Ichikawa S., Sakakibara H., Piskula M.K., Nakamura T., Kato Y., et al. Accumulation of orally administered quercetin in brain tissue and its antioxidative effects in rats. Free Radic Biol Med 2011, 51(7):1329-1336.
    • (2011) Free Radic Biol Med , vol.51 , Issue.7 , pp. 1329-1336
    • Ishisaka, A.1    Ichikawa, S.2    Sakakibara, H.3    Piskula, M.K.4    Nakamura, T.5    Kato, Y.6
  • 87
    • 33144467452 scopus 로고    scopus 로고
    • Kinetics of genistein and its conjugated metabolites in pregnant Sprague-Dawley rats following single and repeated genistein administration
    • Soucy N.V., Parkinson H.D., Sochaski M.A., Borghoff S.J. Kinetics of genistein and its conjugated metabolites in pregnant Sprague-Dawley rats following single and repeated genistein administration. Toxicol Sci 2006, 90(1):230-240.
    • (2006) Toxicol Sci , vol.90 , Issue.1 , pp. 230-240
    • Soucy, N.V.1    Parkinson, H.D.2    Sochaski, M.A.3    Borghoff, S.J.4
  • 88
    • 33644544400 scopus 로고    scopus 로고
    • Lactational transfer of the soy isoflavone, genistein, in Sprague-Dawley rats consuming dietary genistein
    • Doerge D.R., Twaddle N.C., Churchwell M.I., Newbold R.R., Delclos K.B. Lactational transfer of the soy isoflavone, genistein, in Sprague-Dawley rats consuming dietary genistein. Reprod Toxicol 2006, 21(3):307-312.
    • (2006) Reprod Toxicol , vol.21 , Issue.3 , pp. 307-312
    • Doerge, D.R.1    Twaddle, N.C.2    Churchwell, M.I.3    Newbold, R.R.4    Delclos, K.B.5
  • 89
    • 33845600030 scopus 로고    scopus 로고
    • Uptake and distribution of catechins in fetal organs following in utero exposure in rats
    • Chu K.O., Wang C.C., Chu C.Y., Choy K.W., Pang C.P., Rogers M.S. Uptake and distribution of catechins in fetal organs following in utero exposure in rats. Hum Reprod 2007, 22(1):280-287.
    • (2007) Hum Reprod , vol.22 , Issue.1 , pp. 280-287
    • Chu, K.O.1    Wang, C.C.2    Chu, C.Y.3    Choy, K.W.4    Pang, C.P.5    Rogers, M.S.6
  • 92
    • 84861576692 scopus 로고    scopus 로고
    • Bilberry and blueberry anthocyanins act as powerful intracellular antioxidants in mammalian cells
    • Bornsek S.M., Ziberna L., Polak T., Vanzo A., Ulrih N.P., Abram V., et al. Bilberry and blueberry anthocyanins act as powerful intracellular antioxidants in mammalian cells. Food Chem 2012, 134(4):1878-1884.
    • (2012) Food Chem , vol.134 , Issue.4 , pp. 1878-1884
    • Bornsek, S.M.1    Ziberna, L.2    Polak, T.3    Vanzo, A.4    Ulrih, N.P.5    Abram, V.6
  • 93
    • 50449099573 scopus 로고    scopus 로고
    • Antioxidant effectiveness of phenolic apple juice extracts and their gut fermentation products in the human colon carcinoma cell line Caco-2
    • Bellion P., Hofmann T., Pool-Zobel B.L., Will F., Dietrich H., Knaup B., et al. Antioxidant effectiveness of phenolic apple juice extracts and their gut fermentation products in the human colon carcinoma cell line Caco-2. J Agric Food Chem 2008, 56(15):6310-6317.
    • (2008) J Agric Food Chem , vol.56 , Issue.15 , pp. 6310-6317
    • Bellion, P.1    Hofmann, T.2    Pool-Zobel, B.L.3    Will, F.4    Dietrich, H.5    Knaup, B.6
  • 94
    • 0030694248 scopus 로고    scopus 로고
    • Modulation of liver canalicular transport processes by the tyrosine-kinase inhibitor genistein: implications of genistein metabolism in the rat
    • Jager W., Winter O., Halper B., Salamon A., Sartori M., Gajdzik L., et al. Modulation of liver canalicular transport processes by the tyrosine-kinase inhibitor genistein: implications of genistein metabolism in the rat. Hepatology 1997, 26(6):1467-1476.
    • (1997) Hepatology , vol.26 , Issue.6 , pp. 1467-1476
    • Jager, W.1    Winter, O.2    Halper, B.3    Salamon, A.4    Sartori, M.5    Gajdzik, L.6
  • 95
    • 84872682955 scopus 로고    scopus 로고
    • The endothelial plasma membrane transporter bilitranslocase mediates rat aortic vasodilation induced by anthocyanins
    • Ziberna L., Lunder M., Tramer F., Drevensek G., Passamonti S. The endothelial plasma membrane transporter bilitranslocase mediates rat aortic vasodilation induced by anthocyanins. Nutr Metab Cardiovasc Dis 2013, 23(1):68-74.
    • (2013) Nutr Metab Cardiovasc Dis , vol.23 , Issue.1 , pp. 68-74
    • Ziberna, L.1    Lunder, M.2    Tramer, F.3    Drevensek, G.4    Passamonti, S.5
  • 97
    • 78049425316 scopus 로고    scopus 로고
    • The impact of fruit flavonoids on memory and cognition
    • Spencer J.P. The impact of fruit flavonoids on memory and cognition. Br J Nutr 2010, 104(Suppl. 3):40-47.
    • (2010) Br J Nutr , vol.104 , Issue.SUPPL. 3 , pp. 40-47
    • Spencer, J.P.1
  • 98
    • 77949501544 scopus 로고    scopus 로고
    • Concord grape juice supplementation improves memory function in older adults with mild cognitive impairment
    • Krikorian R., Nash T.A., Shidler M.D., Shukitt-Hale B., Joseph J.A. Concord grape juice supplementation improves memory function in older adults with mild cognitive impairment. Br J Nutr 2010, 103(5):730-734.
    • (2010) Br J Nutr , vol.103 , Issue.5 , pp. 730-734
    • Krikorian, R.1    Nash, T.A.2    Shidler, M.D.3    Shukitt-Hale, B.4    Joseph, J.A.5
  • 100
    • 77950635550 scopus 로고    scopus 로고
    • Recent research on polyphenolics in vision and eye health
    • Kalt W., Hanneken A., Milbury P., Tremblay F. Recent research on polyphenolics in vision and eye health. J Agric Food Chem 2010, 58(7):4001-4007.
    • (2010) J Agric Food Chem , vol.58 , Issue.7 , pp. 4001-4007
    • Kalt, W.1    Hanneken, A.2    Milbury, P.3    Tremblay, F.4
  • 102
    • 0038018460 scopus 로고    scopus 로고
    • The stomach as a site for anthocyanins absorption from food
    • Passamonti S., Vrhovsek U., Vanzo A., Mattivi F. The stomach as a site for anthocyanins absorption from food. FEBS Lett 2003, 544(1-3):210-213.
    • (2003) FEBS Lett , vol.544 , Issue.1-3 , pp. 210-213
    • Passamonti, S.1    Vrhovsek, U.2    Vanzo, A.3    Mattivi, F.4
  • 103
    • 33750353446 scopus 로고    scopus 로고
    • Flavonoid-mediated inhibition of intestinal ABC transporters may affect the oral bioavailability of drugs, food-borne toxic compounds and bioactive ingredients
    • Brand W., Schutte M., Williamson G. Flavonoid-mediated inhibition of intestinal ABC transporters may affect the oral bioavailability of drugs, food-borne toxic compounds and bioactive ingredients. Biomed Pharmacother 2006, 60:508-519.
    • (2006) Biomed Pharmacother , vol.60 , pp. 508-519
    • Brand, W.1    Schutte, M.2    Williamson, G.3
  • 105
    • 36249009108 scopus 로고    scopus 로고
    • Interaction characteristics of flavonoids with human organic anion transporter 1 (hOAT1) and 3 (hOAT3)
    • Hong S.S., Seo K., Lim S.-C., Han H.-K. Interaction characteristics of flavonoids with human organic anion transporter 1 (hOAT1) and 3 (hOAT3). Pharmacol Res 2007, 56(6):468-4673.
    • (2007) Pharmacol Res , vol.56 , Issue.6 , pp. 468-4673
    • Hong, S.S.1    Seo, K.2    Lim, S.-C.3    Han, H.-K.4
  • 107
    • 79953686193 scopus 로고    scopus 로고
    • Quantitative targeted absolute proteomics of human blood-brain barrier transporters and receptors
    • Uchida Y., Ohtsuki S., Katsukura Y., Ikeda C., Suzuki T., Kamiie J., et al. Quantitative targeted absolute proteomics of human blood-brain barrier transporters and receptors. J Neurochem 2011, 117(2):333-345.
    • (2011) J Neurochem , vol.117 , Issue.2 , pp. 333-345
    • Uchida, Y.1    Ohtsuki, S.2    Katsukura, Y.3    Ikeda, C.4    Suzuki, T.5    Kamiie, J.6
  • 108
    • 27544453625 scopus 로고    scopus 로고
    • Flavonoids as a novel class of human organic anion-transporting polypeptide OATP1B1 (OATP-C) modulators
    • Wang X., Wolkoff A.W., Morris M.E. Flavonoids as a novel class of human organic anion-transporting polypeptide OATP1B1 (OATP-C) modulators. Drug Metab Dispos 2005, 33(11):1666-1672.
    • (2005) Drug Metab Dispos , vol.33 , Issue.11 , pp. 1666-1672
    • Wang, X.1    Wolkoff, A.W.2    Morris, M.E.3
  • 109
    • 33846469955 scopus 로고    scopus 로고
    • Flavonoids modulate monocarboxylate transporter-1-mediated transport of γ-hydroxybutyrate in vitro and in vivo
    • Wang Q., Morris M.E. Flavonoids modulate monocarboxylate transporter-1-mediated transport of γ-hydroxybutyrate in vitro and in vivo. Drug Metab Dispos 2007, 35(2):201-208.
    • (2007) Drug Metab Dispos , vol.35 , Issue.2 , pp. 201-208
    • Wang, Q.1    Morris, M.E.2
  • 110
    • 77957903556 scopus 로고    scopus 로고
    • Influence of the flavonoids apigenin, kaempferol, and quercetin on the function of organic anion transporting polypeptides 1A2 and 2B1
    • Mandery K., Bujok K., Schmidt I., Keiser M., Siegmund W., Balk B., et al. Influence of the flavonoids apigenin, kaempferol, and quercetin on the function of organic anion transporting polypeptides 1A2 and 2B1. Biochem Pharmacol 2010, 80(11):1746-1753.
    • (2010) Biochem Pharmacol , vol.80 , Issue.11 , pp. 1746-1753
    • Mandery, K.1    Bujok, K.2    Schmidt, I.3    Keiser, M.4    Siegmund, W.5    Balk, B.6
  • 111
    • 77953611901 scopus 로고    scopus 로고
    • Effects of single and multiple flavonoids on BCRP-mediated accumulation, cytotoxicity and transport of mitoxantrone in vitro
    • An G., Morris M.E. Effects of single and multiple flavonoids on BCRP-mediated accumulation, cytotoxicity and transport of mitoxantrone in vitro. Pharm Res 2010, 27(7):1296-1308.
    • (2010) Pharm Res , vol.27 , Issue.7 , pp. 1296-1308
    • An, G.1    Morris, M.E.2
  • 112
  • 113
    • 0037013196 scopus 로고    scopus 로고
    • Flavonoid inhibition of sodium-dependent vitamin C transporter 1 (SVCT1) and glucose transporter isoform 2 (GLUT2), intestinal transporters for vitamin C and glucose
    • Song J., Kwon O., Chen S., Daruwala R., Eck P., Park J.B., et al. Flavonoid inhibition of sodium-dependent vitamin C transporter 1 (SVCT1) and glucose transporter isoform 2 (GLUT2), intestinal transporters for vitamin C and glucose. J Biol Chem 2002, 277(18):15252-15260.
    • (2002) J Biol Chem , vol.277 , Issue.18 , pp. 15252-15260
    • Song, J.1    Kwon, O.2    Chen, S.3    Daruwala, R.4    Eck, P.5    Park, J.B.6
  • 114
    • 0035813012 scopus 로고    scopus 로고
    • Toxicological relevance of the multidrug resistance protein 1, MRP1 (ABCC1) and related transporters
    • Leslie E.M., Deeley R.G., Cole S.P. Toxicological relevance of the multidrug resistance protein 1, MRP1 (ABCC1) and related transporters. Toxicology 2001, 167(1):3-23.
    • (2001) Toxicology , vol.167 , Issue.1 , pp. 3-23
    • Leslie, E.M.1    Deeley, R.G.2    Cole, S.P.3
  • 115
    • 0033051339 scopus 로고    scopus 로고
    • Transport of the flavonoid chrysin and its conjugated metabolites by the human intestinal cell line Caco-2
    • Walle U.K., Galijatovic A., Walle T. Transport of the flavonoid chrysin and its conjugated metabolites by the human intestinal cell line Caco-2. Biochem Pharmacol 1999, 58(3):431-438.
    • (1999) Biochem Pharmacol , vol.58 , Issue.3 , pp. 431-438
    • Walle, U.K.1    Galijatovic, A.2    Walle, T.3
  • 116
    • 22144481699 scopus 로고    scopus 로고
    • Structure activity relationships and quantitative structure activity relationships for the flavonoid-mediated inhibition of breast cancer resistance protein
    • Zhang S., Yang X., Coburn R.A., Morris M.E. Structure activity relationships and quantitative structure activity relationships for the flavonoid-mediated inhibition of breast cancer resistance protein. Biochem Pharmacol 2005, 70(4):627-639.
    • (2005) Biochem Pharmacol , vol.70 , Issue.4 , pp. 627-639
    • Zhang, S.1    Yang, X.2    Coburn, R.A.3    Morris, M.E.4
  • 117
    • 33947233105 scopus 로고    scopus 로고
    • Phytochemicals induce breast cancer resistance protein in Caco-2 cells and enhance the transport of benzo[a]pyrene-3-sulfate
    • Ebert B., Seidel A., Lampen A. Phytochemicals induce breast cancer resistance protein in Caco-2 cells and enhance the transport of benzo[a]pyrene-3-sulfate. Toxicol Sci 2007, 96(2):227-236.
    • (2007) Toxicol Sci , vol.96 , Issue.2 , pp. 227-236
    • Ebert, B.1    Seidel, A.2    Lampen, A.3
  • 118
    • 12744256734 scopus 로고    scopus 로고
    • Quantitative structure activity relationship studies on the flavonoid mediated inhibition of multidrug resistance proteins 1 and 2
    • van Zanden J.J., Wortelboer H.M., Bijlsma S., Punt A., Usta M., Bladeren P.J., et al. Quantitative structure activity relationship studies on the flavonoid mediated inhibition of multidrug resistance proteins 1 and 2. Biochem Pharmacol 2005, 69(4):699-708.
    • (2005) Biochem Pharmacol , vol.69 , Issue.4 , pp. 699-708
    • van Zanden, J.J.1    Wortelboer, H.M.2    Bijlsma, S.3    Punt, A.4    Usta, M.5    Bladeren, P.J.6
  • 119
    • 33845186252 scopus 로고    scopus 로고
    • Properties of flavonoids influencing the binding to bilitranslocase investigated by neural network modelling
    • Karawajczyk A., Drgan V., Medic N., Oboh G., Passamonti S., Novic M. Properties of flavonoids influencing the binding to bilitranslocase investigated by neural network modelling. Biochem Pharmacol 2007, 73(2):308-320.
    • (2007) Biochem Pharmacol , vol.73 , Issue.2 , pp. 308-320
    • Karawajczyk, A.1    Drgan, V.2    Medic, N.3    Oboh, G.4    Passamonti, S.5    Novic, M.6
  • 120
    • 18844425527 scopus 로고    scopus 로고
    • Involvement of P-glycoprotein in regulating cellular levels of Ginkgo flavonols: quercetin, kaempferol, and isorhamnetin
    • Wang Y., Cao J., Zeng S. Involvement of P-glycoprotein in regulating cellular levels of Ginkgo flavonols: quercetin, kaempferol, and isorhamnetin. J Pharm Pharmacol 2005, 57(6):751-758.
    • (2005) J Pharm Pharmacol , vol.57 , Issue.6 , pp. 751-758
    • Wang, Y.1    Cao, J.2    Zeng, S.3
  • 121
    • 35848970970 scopus 로고    scopus 로고
    • Inhibition effect of flavonoids on monocarboxylate transporter 1 (MCT1) in Caco-2 cells
    • Shim C.K., Cheon E.P., Kang K.W., Seo K.S., Han H.K. Inhibition effect of flavonoids on monocarboxylate transporter 1 (MCT1) in Caco-2 cells. J Pharm Pharmacol 2007, 59(11):1515-1519.
    • (2007) J Pharm Pharmacol , vol.59 , Issue.11 , pp. 1515-1519
    • Shim, C.K.1    Cheon, E.P.2    Kang, K.W.3    Seo, K.S.4    Han, H.K.5
  • 122
    • 36249009108 scopus 로고    scopus 로고
    • Interaction characteristics of flavonoids with human organic anion transporter 1 (hOAT1) and 3 (hOAT3)
    • Hong S.S., Seo K., Lim S.C., Han H. Interaction characteristics of flavonoids with human organic anion transporter 1 (hOAT1) and 3 (hOAT3). Pharmacol Res 2007, 56(6):468-473.
    • (2007) Pharmacol Res , vol.56 , Issue.6 , pp. 468-473
    • Hong, S.S.1    Seo, K.2    Lim, S.C.3    Han, H.4
  • 123
    • 34249316879 scopus 로고    scopus 로고
    • Morin (3,5,7,2',4'-pentahydroxyflavone) exhibits potent inhibitory actions on urate transport by the human urate anion transporter (hURAT1) expressed in human embryonic kidney cells
    • Yu Z., Fong W.P., Cheng C.H. Morin (3,5,7,2',4'-pentahydroxyflavone) exhibits potent inhibitory actions on urate transport by the human urate anion transporter (hURAT1) expressed in human embryonic kidney cells. Drug Metab Dispos 2007, 35(6):981-986.
    • (2007) Drug Metab Dispos , vol.35 , Issue.6 , pp. 981-986
    • Yu, Z.1    Fong, W.P.2    Cheng, C.H.3
  • 124
    • 58149349823 scopus 로고    scopus 로고
    • +-dependent l-ascorbic acid transporter SVCT2 expressed in brainstem cells, neurons, and neuroblastoma cells is inhibited by flavonoids
    • +-dependent l-ascorbic acid transporter SVCT2 expressed in brainstem cells, neurons, and neuroblastoma cells is inhibited by flavonoids. J Neurochem 2009, 108(3):563-577.
    • (2009) J Neurochem , vol.108 , Issue.3 , pp. 563-577
    • Caprile, T.1    Salazar, K.2    Astuya, A.3    Cisternas, P.4    Silva-Alvarez, C.5    Montecinos, H.6
  • 125
    • 0035033774 scopus 로고    scopus 로고
    • Modulation of multidrug resistance protein 1 (MRP1/ABCC1) transport and ATPase activities by interaction with dietary flavonoids
    • Leslie E.M., Mao Q., Oleschuk C.J., Deeley R.G., Cole S.P. Modulation of multidrug resistance protein 1 (MRP1/ABCC1) transport and ATPase activities by interaction with dietary flavonoids. Mol Pharmacol 2001, 59(5):1171-1180.
    • (2001) Mol Pharmacol , vol.59 , Issue.5 , pp. 1171-1180
    • Leslie, E.M.1    Mao, Q.2    Oleschuk, C.J.3    Deeley, R.G.4    Cole, S.P.5
  • 126
    • 0034600237 scopus 로고    scopus 로고
    • Effect of bioflavonoids on vincristine transport across blood-brain barrier
    • Mitsunaga Y., Takanaga H., Matsuo H., Naito M., Tsuruo T., Ohtani H., et al. Effect of bioflavonoids on vincristine transport across blood-brain barrier. Eur J Pharmacol 2000, 395(3):193-201.
    • (2000) Eur J Pharmacol , vol.395 , Issue.3 , pp. 193-201
    • Mitsunaga, Y.1    Takanaga, H.2    Matsuo, H.3    Naito, M.4    Tsuruo, T.5    Ohtani, H.6
  • 127
    • 25444524567 scopus 로고    scopus 로고
    • Modulatory effects of plant phenols on human multidrug-resistance proteins 1, 4 and 5 (ABCC1, 4 and 5)
    • Wu C.P., Calcagno A.M., Hladky S.B., Ambudkar S.V., Barrand M.A. Modulatory effects of plant phenols on human multidrug-resistance proteins 1, 4 and 5 (ABCC1, 4 and 5). FEBS J 2005, 272(18):4725-4740.
    • (2005) FEBS J , vol.272 , Issue.18 , pp. 4725-4740
    • Wu, C.P.1    Calcagno, A.M.2    Hladky, S.B.3    Ambudkar, S.V.4    Barrand, M.A.5
  • 128
    • 73949086125 scopus 로고    scopus 로고
    • Species difference in the effect of grapefruit juice on intestinal absorption of talinolol between human and rat
    • Shirasaka Y., Kuraoka E., Spahn-Langguth H., Nakanishi T., Langguth P., Tamai I. Species difference in the effect of grapefruit juice on intestinal absorption of talinolol between human and rat. J Pharmacol Exp Ther 2010, 332(1):181-189.
    • (2010) J Pharmacol Exp Ther , vol.332 , Issue.1 , pp. 181-189
    • Shirasaka, Y.1    Kuraoka, E.2    Spahn-Langguth, H.3    Nakanishi, T.4    Langguth, P.5    Tamai, I.6
  • 129
    • 0034770989 scopus 로고    scopus 로고
    • Transport and metabolism of the tea flavonoid (-)-epicatechin by the human intestinal cell line Caco-2
    • Vaidyanathan J.B., Walle T. Transport and metabolism of the tea flavonoid (-)-epicatechin by the human intestinal cell line Caco-2. Pharm Res 2001, 18(10):1420-1425.
    • (2001) Pharm Res , vol.18 , Issue.10 , pp. 1420-1425
    • Vaidyanathan, J.B.1    Walle, T.2
  • 130
    • 0036399061 scopus 로고    scopus 로고
    • Elevation of P-glycoprotein function by a catechin in green tea
    • Wang E.J., Barecki-Roach M., Johnson W.W. Elevation of P-glycoprotein function by a catechin in green tea. Biochem Biophys Res Commun 2002, 297(2):412-418.
    • (2002) Biochem Biophys Res Commun , vol.297 , Issue.2 , pp. 412-418
    • Wang, E.J.1    Barecki-Roach, M.2    Johnson, W.W.3
  • 131
    • 79954989371 scopus 로고    scopus 로고
    • Interactions of green tea catechins with organic anion-transporting polypeptides
    • Roth M., Timmermann B.N., Hagenbuch B. Interactions of green tea catechins with organic anion-transporting polypeptides. Drug Metab Dispos 2011, 39(5):920-926.
    • (2011) Drug Metab Dispos , vol.39 , Issue.5 , pp. 920-926
    • Roth, M.1    Timmermann, B.N.2    Hagenbuch, B.3
  • 132
    • 0141849078 scopus 로고    scopus 로고
    • Involvement of multidrug resistance-associated proteins in regulating cellular levels of (-)-epigallocatechin-3-gallate and its methyl metabolites
    • Hong J., Lambert J., Lee S., Sinko P. Involvement of multidrug resistance-associated proteins in regulating cellular levels of (-)-epigallocatechin-3-gallate and its methyl metabolites. Biochem Biophys Res Commun 2003, 310(1):222-227.
    • (2003) Biochem Biophys Res Commun , vol.310 , Issue.1 , pp. 222-227
    • Hong, J.1    Lambert, J.2    Lee, S.3    Sinko, P.4
  • 133
    • 0028136603 scopus 로고
    • Competitive inhibition by genistein and ATP dependence of daunorubicin transport in intact MRP overexpressing human small cell lung cancer cells
    • Versantvoort C.H., Broxterman H.J., Lankelma J., Feller N., Pinedo H.M. Competitive inhibition by genistein and ATP dependence of daunorubicin transport in intact MRP overexpressing human small cell lung cancer cells. Biochem Pharmacol 1994, 48(6):1129-1136.
    • (1994) Biochem Pharmacol , vol.48 , Issue.6 , pp. 1129-1136
    • Versantvoort, C.H.1    Broxterman, H.J.2    Lankelma, J.3    Feller, N.4    Pinedo, H.M.5
  • 134
    • 0033020068 scopus 로고    scopus 로고
    • Transport of genistein-7-glucoside by human intestinal CACO-2 cells: potential role for MRP2
    • Walle U.K., French K.L., Walgren R.A., Walle T. Transport of genistein-7-glucoside by human intestinal CACO-2 cells: potential role for MRP2. Res Commun Mol Pathol Pharmacol 1999, 103(1):45-56.
    • (1999) Res Commun Mol Pathol Pharmacol , vol.103 , Issue.1 , pp. 45-56
    • Walle, U.K.1    French, K.L.2    Walgren, R.A.3    Walle, T.4
  • 135
    • 3042569646 scopus 로고    scopus 로고
    • Phytoestrogens/flavonoids reverse breast cancer resistance protein/ABCG2-mediated multidrug resistance
    • Imai Y., Tsukahara S., Asada S., Sugimoto Y. Phytoestrogens/flavonoids reverse breast cancer resistance protein/ABCG2-mediated multidrug resistance. Cancer Res 2004, 64(12):4346-4352.
    • (2004) Cancer Res , vol.64 , Issue.12 , pp. 4346-4352
    • Imai, Y.1    Tsukahara, S.2    Asada, S.3    Sugimoto, Y.4
  • 136
    • 34748926909 scopus 로고    scopus 로고
    • Effect of breast cancer resistance protein (Bcrp/Abcg2) on the disposition of phytoestrogens
    • Enokizono J., Kusuhara H., Sugiyama Y. Effect of breast cancer resistance protein (Bcrp/Abcg2) on the disposition of phytoestrogens. Mol Pharmacol 2007, 72(4):967-975.
    • (2007) Mol Pharmacol , vol.72 , Issue.4 , pp. 967-975
    • Enokizono, J.1    Kusuhara, H.2    Sugiyama, Y.3
  • 137
    • 0031060647 scopus 로고    scopus 로고
    • Inhibition of drug transport by genistein in multidrug-resistant cells expressing P-glycoprotein
    • Castro A.F., Altenberg G.A. Inhibition of drug transport by genistein in multidrug-resistant cells expressing P-glycoprotein. Biochem Pharmacol 1997, 53(1):89-93.
    • (1997) Biochem Pharmacol , vol.53 , Issue.1 , pp. 89-93
    • Castro, A.F.1    Altenberg, G.A.2
  • 138
    • 33845626164 scopus 로고    scopus 로고
    • Expression and characterization of vitamin C transporter in the human trophoblast cell line HTR-8/SVneo: effect of steroids, flavonoids and NSAIDs
    • Biondi C., Pavan B., Dalpiaz A., Medici S., Lunghi L., Vesce F. Expression and characterization of vitamin C transporter in the human trophoblast cell line HTR-8/SVneo: effect of steroids, flavonoids and NSAIDs. Mol Hum Reprod 2007, 13(1):77-83.
    • (2007) Mol Hum Reprod , vol.13 , Issue.1 , pp. 77-83
    • Biondi, C.1    Pavan, B.2    Dalpiaz, A.3    Medici, S.4    Lunghi, L.5    Vesce, F.6
  • 139
    • 71649106260 scopus 로고    scopus 로고
    • Berry anthocyanins and anthocyanidins exhibit distinct affinities for the efflux transporters BCRP and MDR1
    • Dreiseitel A., Oosterhuis B., Vukman K.V., Schreier P., Oehme A., Locher S., et al. Berry anthocyanins and anthocyanidins exhibit distinct affinities for the efflux transporters BCRP and MDR1. Br J Pharmacol 2009, 158(8):1942-1950.
    • (2009) Br J Pharmacol , vol.158 , Issue.8 , pp. 1942-1950
    • Dreiseitel, A.1    Oosterhuis, B.2    Vukman, K.V.3    Schreier, P.4    Oehme, A.5    Locher, S.6
  • 141
    • 13844271387 scopus 로고    scopus 로고
    • Bioavailability and bioefficacy of polyphenols in humans. II. Review of 93 intervention studies
    • Williamson G., Manach C. Bioavailability and bioefficacy of polyphenols in humans. II. Review of 93 intervention studies. Am J Clin Nutr 2005, 81(1):243S-255S.
    • (2005) Am J Clin Nutr , vol.81 , Issue.1
    • Williamson, G.1    Manach, C.2
  • 142
    • 75749097381 scopus 로고    scopus 로고
    • Quercetin and naringenin transport across human intestinal Caco-2 cells
    • Nait Chabane M., Al Ahmad A., Peluso J., Muller C.D., Ubeaud G. Quercetin and naringenin transport across human intestinal Caco-2 cells. J Pharm Pharmacol 2009, 61(11):1473-1483.
    • (2009) J Pharm Pharmacol , vol.61 , Issue.11 , pp. 1473-1483
    • Nait Chabane, M.1    Al Ahmad, A.2    Peluso, J.3    Muller, C.D.4    Ubeaud, G.5
  • 143
    • 0033846534 scopus 로고    scopus 로고
    • Cellular uptake of dietary flavonoid quercetin 4'β-glucoside by sodium-dependent glucose transporter SGLT1
    • Walgren R.A., Lin J.-T., Kinne R.K.H., Walle T. Cellular uptake of dietary flavonoid quercetin 4'β-glucoside by sodium-dependent glucose transporter SGLT1. J Pharmacol Exp Ther 2000, 294(3):837-843.
    • (2000) J Pharmacol Exp Ther , vol.294 , Issue.3 , pp. 837-843
    • Walgren, R.A.1    Lin, J.-T.2    Kinne, R.K.H.3    Walle, T.4
  • 144
    • 34547135694 scopus 로고    scopus 로고
    • +/glucose transporter when expressed in Xenopus laevis oocytes, but effectively inhibit electrogenic glucose uptake
    • +/glucose transporter when expressed in Xenopus laevis oocytes, but effectively inhibit electrogenic glucose uptake. J Pharmacol Exp Ther 2007, 322(2):829-835.
    • (2007) J Pharmacol Exp Ther , vol.322 , Issue.2 , pp. 829-835
    • Kottra, G.1    Daniel, H.2
  • 146
    • 82155162339 scopus 로고    scopus 로고
    • Interaction of hesperetin glucuronide conjugates with human BCRP, MRP2 and MRP3 as detected in membrane vesicles of overexpressing baculovirus-infected Sf9 cells
    • Brand W.W., Oosterhuis B.B., Krajcsi P.P., Barron D.D., Dionisi F.F., van Bladeren P.J.P., et al. Interaction of hesperetin glucuronide conjugates with human BCRP, MRP2 and MRP3 as detected in membrane vesicles of overexpressing baculovirus-infected Sf9 cells. Biopharm Drug Dispos 2011, 32(9):530-535.
    • (2011) Biopharm Drug Dispos , vol.32 , Issue.9 , pp. 530-535
    • Brand, W.W.1    Oosterhuis, B.B.2    Krajcsi, P.P.3    Barron, D.D.4    Dionisi, F.F.5    van Bladeren, P.J.P.6
  • 147
    • 0142241274 scopus 로고    scopus 로고
    • Cellular uptake and efflux of the tea flavonoid (-)epicatechin-3-gallate in the human intestinal cell line Caco-2
    • Vaidyanathan J.B., Walle T. Cellular uptake and efflux of the tea flavonoid (-)epicatechin-3-gallate in the human intestinal cell line Caco-2. J Pharmacol Exp Ther 2003, 307(2):745-752.
    • (2003) J Pharmacol Exp Ther , vol.307 , Issue.2 , pp. 745-752
    • Vaidyanathan, J.B.1    Walle, T.2
  • 148
    • 33751074139 scopus 로고    scopus 로고
    • Cellular expression of monocarboxylate transporters (MCT) in the digestive tract of the mouse, rat, and humans, with special reference to slc5a8
    • Iwanaga T., Takebe K., Kato I., Karaki S., Kuwahara A. Cellular expression of monocarboxylate transporters (MCT) in the digestive tract of the mouse, rat, and humans, with special reference to slc5a8. Biomed Res 2006, 27(5):243-254.
    • (2006) Biomed Res , vol.27 , Issue.5 , pp. 243-254
    • Iwanaga, T.1    Takebe, K.2    Kato, I.3    Karaki, S.4    Kuwahara, A.5
  • 149
    • 70449562659 scopus 로고    scopus 로고
    • Absorption of anthocyanins through intestinal epithelial cells - Putative involvement of GLUT2
    • Faria A.A., Pestana D.D., Azevedo J.J., Martel F.F., de Freitas V.V., Azevedo I.I., et al. Absorption of anthocyanins through intestinal epithelial cells - Putative involvement of GLUT2. Mol Nutr Food Res 2009, 53(11):1430-1437.
    • (2009) Mol Nutr Food Res , vol.53 , Issue.11 , pp. 1430-1437
    • Faria, A.A.1    Pestana, D.D.2    Azevedo, J.J.3    Martel, F.F.4    de Freitas, V.V.5    Azevedo, I.I.6
  • 150
    • 78649820061 scopus 로고    scopus 로고
    • Polyphenols and phenolic acids from strawberry and apple decrease glucose uptake and transport by human intestinal Caco-2 cells
    • Manzano S., Williamson G. Polyphenols and phenolic acids from strawberry and apple decrease glucose uptake and transport by human intestinal Caco-2 cells. Mol Nutr Food Res 2010, 54(12):1773-1780.
    • (2010) Mol Nutr Food Res , vol.54 , Issue.12 , pp. 1773-1780
    • Manzano, S.1    Williamson, G.2
  • 151
    • 68349144331 scopus 로고    scopus 로고
    • Bioavailability of flavonoids: a review of their membrane transport and the function of bilitranslocase in animal and plant organisms
    • Passamonti S., Terdoslavich M., Franca R., Vanzo A., Tramer F., Braidot E., et al. Bioavailability of flavonoids: a review of their membrane transport and the function of bilitranslocase in animal and plant organisms. Curr Drug Metab 2009, 10(4):369-394.
    • (2009) Curr Drug Metab , vol.10 , Issue.4 , pp. 369-394
    • Passamonti, S.1    Terdoslavich, M.2    Franca, R.3    Vanzo, A.4    Tramer, F.5    Braidot, E.6
  • 152
    • 18144387251 scopus 로고    scopus 로고
    • Immunolocalisation of bilitranslocase in mucosecretory and parietal cells of the rat gastric mucosa
    • Nicolin V., Grill V., Micali F., Narducci P., Passamonti S. Immunolocalisation of bilitranslocase in mucosecretory and parietal cells of the rat gastric mucosa. J Mol Histol 2005, 36(1-2):45-50.
    • (2005) J Mol Histol , vol.36 , Issue.1-2 , pp. 45-50
    • Nicolin, V.1    Grill, V.2    Micali, F.3    Narducci, P.4    Passamonti, S.5
  • 153
    • 34047162392 scopus 로고    scopus 로고
    • Role of P-glycoprotein in the intestinal absorption of glabridin, an active flavonoid from the root of Glycyrrhiza glabra
    • Cao J.J., Chen X.X., Liang J.J., Yu X.-Q.X., Xu A.-L.A., Chan E.E., et al. Role of P-glycoprotein in the intestinal absorption of glabridin, an active flavonoid from the root of Glycyrrhiza glabra. Drug Metab Dispos 2007, 35(4):539-553.
    • (2007) Drug Metab Dispos , vol.35 , Issue.4 , pp. 539-553
    • Cao, J.J.1    Chen, X.X.2    Liang, J.J.3    Yu, X.-Q.X.4    Xu, A.-L.A.5    Chan, E.E.6
  • 154
    • 21744461919 scopus 로고    scopus 로고
    • Breast cancer resistance protein (Bcrp1/Abcg2) limits net intestinal uptake of quercetin in rats by facilitating apical efflux of glucuronides
    • Sesink A.L., Arts I.C., de Boer V.C., Breedveld P., Schellens J.H., Hollman P.C., et al. Breast cancer resistance protein (Bcrp1/Abcg2) limits net intestinal uptake of quercetin in rats by facilitating apical efflux of glucuronides. Mol Pharmacol 2005, 67(6):1999-2006.
    • (2005) Mol Pharmacol , vol.67 , Issue.6 , pp. 1999-2006
    • Sesink, A.L.1    Arts, I.C.2    de Boer, V.C.3    Breedveld, P.4    Schellens, J.H.5    Hollman, P.C.6
  • 155
    • 28144464297 scopus 로고    scopus 로고
    • Disposition of flavonoids via recycling: comparison of intestinal versus hepatic disposition
    • Chen J., Wang S., Jia X., Bajimaya S., Lin H., Tam V.H., et al. Disposition of flavonoids via recycling: comparison of intestinal versus hepatic disposition. Drug Metab Dispos 2005, 33(12):1777-1784.
    • (2005) Drug Metab Dispos , vol.33 , Issue.12 , pp. 1777-1784
    • Chen, J.1    Wang, S.2    Jia, X.3    Bajimaya, S.4    Lin, H.5    Tam, V.H.6
  • 156
    • 0037371414 scopus 로고    scopus 로고
    • Metabolism of flavonoids via enteric recycling: role of intestinal disposition
    • Chen J., Lin H., Hu M. Metabolism of flavonoids via enteric recycling: role of intestinal disposition. J Pharmacol Exp Ther 2003, 304(3):1228-1235.
    • (2003) J Pharmacol Exp Ther , vol.304 , Issue.3 , pp. 1228-1235
    • Chen, J.1    Lin, H.2    Hu, M.3
  • 158
    • 80053386882 scopus 로고    scopus 로고
    • Experimental determination and prediction of bilitranslocase transport activity
    • Zuperl S., Fornasaro S., Novic M., Passamonti S. Experimental determination and prediction of bilitranslocase transport activity. Anal Chim Acta 2011, 705(1-2):322-333.
    • (2011) Anal Chim Acta , vol.705 , Issue.1-2 , pp. 322-333
    • Zuperl, S.1    Fornasaro, S.2    Novic, M.3    Passamonti, S.4
  • 160
    • 27644599384 scopus 로고    scopus 로고
    • Uptake of bilirubin into HepG2 cells assayed by thermal lens spectroscopy. Function of bilitranslocase
    • Passamonti S., Terdoslavich M., Margon A., Cocolo A., Medic N., Micali F., et al. Uptake of bilirubin into HepG2 cells assayed by thermal lens spectroscopy. Function of bilitranslocase. FEBS J 2005, 272(21):5522-5535.
    • (2005) FEBS J , vol.272 , Issue.21 , pp. 5522-5535
    • Passamonti, S.1    Terdoslavich, M.2    Margon, A.3    Cocolo, A.4    Medic, N.5    Micali, F.6
  • 162
    • 84875458443 scopus 로고    scopus 로고
    • Transport by OATP1B1 and OATP1B3 enhances the cytotoxicity of epigallocatechin 3-O-gallate and several quercetin derivatives
    • Zhang Y., Hays A., Noblett A., Thapa M., Hua D.H., Hagenbuch B. Transport by OATP1B1 and OATP1B3 enhances the cytotoxicity of epigallocatechin 3-O-gallate and several quercetin derivatives. J Nat Prod 2013, 76(3):368-373.
    • (2013) J Nat Prod , vol.76 , Issue.3 , pp. 368-373
    • Zhang, Y.1    Hays, A.2    Noblett, A.3    Thapa, M.4    Hua, D.H.5    Hagenbuch, B.6
  • 163
    • 80052584684 scopus 로고    scopus 로고
    • Hepatic metabolism and disposition of baicalein via the coupling of conjugation enzymes and transporters - In vitro and in vivo evidences
    • Zhang L., Li C., Lin G., Krajcsi P., Zuo Z. Hepatic metabolism and disposition of baicalein via the coupling of conjugation enzymes and transporters - In vitro and in vivo evidences. AAPS J 2011, 13(3):378-389.
    • (2011) AAPS J , vol.13 , Issue.3 , pp. 378-389
    • Zhang, L.1    Li, C.2    Lin, G.3    Krajcsi, P.4    Zuo, Z.5
  • 164
    • 12744256734 scopus 로고    scopus 로고
    • Quantitative structure activity relationship studies on the flavonoid mediated inhibition of multidrug resistance proteins 1 and 2
    • van Zanden J.J., Wortelboer H.M., Bijlsma S., Punt A., Usta M., Bladeren PJv., et al. Quantitative structure activity relationship studies on the flavonoid mediated inhibition of multidrug resistance proteins 1 and 2. Biochem Pharmacol 2005, 69(4):699-708.
    • (2005) Biochem Pharmacol , vol.69 , Issue.4 , pp. 699-708
    • van Zanden, J.J.1    Wortelboer, H.M.2    Bijlsma, S.3    Punt, A.4    Usta, M.5    Bladeren, P.6
  • 165
    • 71949113516 scopus 로고    scopus 로고
    • Disposition of naringenin via glucuronidation pathway is affected by compensating efflux transporters of hydrophilic glucuronides
    • Xu H., Kulkarni K.H., Singh R., Yang Z., Wang S.W., Tam V.H., et al. Disposition of naringenin via glucuronidation pathway is affected by compensating efflux transporters of hydrophilic glucuronides. Mol Pharm 2009, 6(6):1703-1715.
    • (2009) Mol Pharm , vol.6 , Issue.6 , pp. 1703-1715
    • Xu, H.1    Kulkarni, K.H.2    Singh, R.3    Yang, Z.4    Wang, S.W.5    Tam, V.H.6
  • 166
    • 74049143120 scopus 로고    scopus 로고
    • Modulation of the activity of ABC transporters (P-glycoprotein, MRP2, BCRP) by flavonoids and drug response
    • Alvarez A., Real R., Perez M., Mendoza G., Prieto J., Merino G. Modulation of the activity of ABC transporters (P-glycoprotein, MRP2, BCRP) by flavonoids and drug response. J Pharm Sci 2010, 99(2):598-617.
    • (2010) J Pharm Sci , vol.99 , Issue.2 , pp. 598-617
    • Alvarez, A.1    Real, R.2    Perez, M.3    Mendoza, G.4    Prieto, J.5    Merino, G.6
  • 167
    • 54349084283 scopus 로고    scopus 로고
    • Hepatic metabolism and biliary excretion of silymarin flavonolignans in isolated perfused rat livers: role of multidrug resistance-associated protein 2 (Abcc2)
    • Miranda S.R., Lee J.K., Brouwer K.L., Wen Z., Smith P.C., Hawke R.L. Hepatic metabolism and biliary excretion of silymarin flavonolignans in isolated perfused rat livers: role of multidrug resistance-associated protein 2 (Abcc2). Drug Metab Dispos 2008, 36(11):2219-2226.
    • (2008) Drug Metab Dispos , vol.36 , Issue.11 , pp. 2219-2226
    • Miranda, S.R.1    Lee, J.K.2    Brouwer, K.L.3    Wen, Z.4    Smith, P.C.5    Hawke, R.L.6
  • 168
    • 83955163683 scopus 로고    scopus 로고
    • Absolute immunoquantification of the expression of ABC transporters P-glycoprotein, breast cancer resistance protein and multidrug resistance-associated protein 2 in human liver and duodenum
    • Tucker T.G., Milne A.M., Fournel-Gigleux S., Fenner K.S., Coughtrie M.W. Absolute immunoquantification of the expression of ABC transporters P-glycoprotein, breast cancer resistance protein and multidrug resistance-associated protein 2 in human liver and duodenum. Biochem Pharmacol 2012, 83(2):279-285.
    • (2012) Biochem Pharmacol , vol.83 , Issue.2 , pp. 279-285
    • Tucker, T.G.1    Milne, A.M.2    Fournel-Gigleux, S.3    Fenner, K.S.4    Coughtrie, M.W.5
  • 169
    • 34547169521 scopus 로고    scopus 로고
    • Expression of thirty-six drug transporter genes in human intestine, liver, kidney, and organotypic cell lines
    • Hilgendorf C., Ahlin G., Seithel A., Artursson P., Ungell A.L., Karlsson J. Expression of thirty-six drug transporter genes in human intestine, liver, kidney, and organotypic cell lines. Drug Metab Dispos 2007, 35(8):1333-1340.
    • (2007) Drug Metab Dispos , vol.35 , Issue.8 , pp. 1333-1340
    • Hilgendorf, C.1    Ahlin, G.2    Seithel, A.3    Artursson, P.4    Ungell, A.L.5    Karlsson, J.6
  • 170
    • 0027218689 scopus 로고
    • Biochemistry of multidrug resistance mediated by the multidrug transporter
    • Gottesman M.M., Pastan I. Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu Rev Biochem 1993, 62:385-427.
    • (1993) Annu Rev Biochem , vol.62 , pp. 385-427
    • Gottesman, M.M.1    Pastan, I.2
  • 171
    • 28744436977 scopus 로고    scopus 로고
    • Structure-activity relationships of the inhibitory effects of flavonoids on P-glycoprotein-mediated transport in KB-C2 cells
    • Kitagawa S., Nabekura T., Takahashi T., Nakamura Y., Sakamoto H., Tano H., et al. Structure-activity relationships of the inhibitory effects of flavonoids on P-glycoprotein-mediated transport in KB-C2 cells. Biol Pharm Bull 2005, 28(12):2274-2278.
    • (2005) Biol Pharm Bull , vol.28 , Issue.12 , pp. 2274-2278
    • Kitagawa, S.1    Nabekura, T.2    Takahashi, T.3    Nakamura, Y.4    Sakamoto, H.5    Tano, H.6
  • 172
    • 77956304287 scopus 로고    scopus 로고
    • A quantitative structure-activity relationship for the modulation effects of flavonoids on P-glycoprotein-mediated transport
    • Sheu M.-T., Liou Y.-B., Kao Y.-H., Lin Y.-K., Ho H.-O. A quantitative structure-activity relationship for the modulation effects of flavonoids on P-glycoprotein-mediated transport. Chem Pharm Bull (Tokyo) 2010, 58(9):1187-1194.
    • (2010) Chem Pharm Bull (Tokyo) , vol.58 , Issue.9 , pp. 1187-1194
    • Sheu, M.-T.1    Liou, Y.-B.2    Kao, Y.-H.3    Lin, Y.-K.4    Ho, H.-O.5
  • 173
    • 72749084863 scopus 로고    scopus 로고
    • Interactions between the flavonoid biochanin A and P-glycoprotein substrates in rats: in vitro and in vivo
    • Zhang S., Sagawa K., Arnold R.D., Tseng E., Wang X., Morris M.E. Interactions between the flavonoid biochanin A and P-glycoprotein substrates in rats: in vitro and in vivo. J Pharm Sci 2010, 99(1):430-441.
    • (2010) J Pharm Sci , vol.99 , Issue.1 , pp. 430-441
    • Zhang, S.1    Sagawa, K.2    Arnold, R.D.3    Tseng, E.4    Wang, X.5    Morris, M.E.6
  • 174
  • 175
    • 83655180989 scopus 로고    scopus 로고
    • Herb-drug interactions: Focus on metabolic enzymes and transporters
    • Choi Y.H., Chin Y.-W., Kim Y.G. Herb-drug interactions: Focus on metabolic enzymes and transporters. Arch Pharm Res 2011, 34(11):1843-1863.
    • (2011) Arch Pharm Res , vol.34 , Issue.11 , pp. 1843-1863
    • Choi, Y.H.1    Chin, Y.-W.2    Kim, Y.G.3
  • 176
    • 62549134050 scopus 로고    scopus 로고
    • Modulation of anticancer drug-induced P-glycoprotein expression by naringin
    • Ali M.M., Agha F.G., El-Sammad N.M., Hassan S.K. Modulation of anticancer drug-induced P-glycoprotein expression by naringin. Z Naturforsch C 2009, 64(1-2):109-116.
    • (2009) Z Naturforsch C , vol.64 , Issue.1-2 , pp. 109-116
    • Ali, M.M.1    Agha, F.G.2    El-Sammad, N.M.3    Hassan, S.K.4
  • 177
    • 33644914487 scopus 로고    scopus 로고
    • Flavonoid-drug interactions: effects of flavonoids on ABC transporters
    • Morris M., Zhang S. Flavonoid-drug interactions: effects of flavonoids on ABC transporters. Life Sci 2006, 78(18):2116-2130.
    • (2006) Life Sci , vol.78 , Issue.18 , pp. 2116-2130
    • Morris, M.1    Zhang, S.2
  • 178
    • 34249297623 scopus 로고    scopus 로고
    • Mechanistic study on the intestinal absorption and disposition of baicalein
    • Zhang L., Lin G., Kovacs B., Jani M., Krajcsi P., Zuo Z. Mechanistic study on the intestinal absorption and disposition of baicalein. Eur J Pharm Sci 2007, 31(3-4):221-231.
    • (2007) Eur J Pharm Sci , vol.31 , Issue.3-4 , pp. 221-231
    • Zhang, L.1    Lin, G.2    Kovacs, B.3    Jani, M.4    Krajcsi, P.5    Zuo, Z.6
  • 180
    • 27144437234 scopus 로고    scopus 로고
    • Blackberry anthocyanins are mainly recovered from urine as methylated and glucuronidated conjugates in humans
    • Felgines C., Talavera S., Texier O., Gil-Izquierdo A., Lamaison J.L., Remesy C. Blackberry anthocyanins are mainly recovered from urine as methylated and glucuronidated conjugates in humans. J Agric Food Chem 2005, 53(20):7721-7772.
    • (2005) J Agric Food Chem , vol.53 , Issue.20 , pp. 7721-7772
    • Felgines, C.1    Talavera, S.2    Texier, O.3    Gil-Izquierdo, A.4    Lamaison, J.L.5    Remesy, C.6
  • 181
    • 13844281685 scopus 로고    scopus 로고
    • Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies
    • Manach C., Williamson G., Morand C., Scalbert A., Remesy C. Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies. Am J Clin Nutr 2005, 81(1):230S-242S.
    • (2005) Am J Clin Nutr , vol.81 , Issue.1
    • Manach, C.1    Williamson, G.2    Morand, C.3    Scalbert, A.4    Remesy, C.5
  • 182
    • 20844456273 scopus 로고    scopus 로고
    • Anthocyanin metabolism in rats and their distribution to digestive area, kidney, and brain
    • Talavera S., Felgines C., Texier O., Besson C., Gil-Izquierdo A., Lamaison J.L., et al. Anthocyanin metabolism in rats and their distribution to digestive area, kidney, and brain. J Agric Food Chem 2005, 53(10):3902-3908.
    • (2005) J Agric Food Chem , vol.53 , Issue.10 , pp. 3902-3908
    • Talavera, S.1    Felgines, C.2    Texier, O.3    Besson, C.4    Gil-Izquierdo, A.5    Lamaison, J.L.6
  • 183
    • 0031761353 scopus 로고    scopus 로고
    • Detecting and measuring bioavailability of phenolics and flavonoids in humans: pharmacokinetics of urinary excretion of dietary ferulic acid
    • Bourne L.C., Rice-Evans C.A. Detecting and measuring bioavailability of phenolics and flavonoids in humans: pharmacokinetics of urinary excretion of dietary ferulic acid. Methods Enzymol 1999, 299:91-106.
    • (1999) Methods Enzymol , vol.299 , pp. 91-106
    • Bourne, L.C.1    Rice-Evans, C.A.2
  • 184
    • 0032817810 scopus 로고    scopus 로고
    • Urinary excretion of hydroxycinnamates and flavonoids after oral and intravenous administration
    • Choudhury R., Srai S.K., Debnam E., Rice-Evans C.A. Urinary excretion of hydroxycinnamates and flavonoids after oral and intravenous administration. Free Radic Biol Med 1999, 27(3-4):278-286.
    • (1999) Free Radic Biol Med , vol.27 , Issue.3-4 , pp. 278-286
    • Choudhury, R.1    Srai, S.K.2    Debnam, E.3    Rice-Evans, C.A.4
  • 185
    • 0033203129 scopus 로고    scopus 로고
    • Urinary metabolites of flavonoids and hydroxycinnamic acids in humans after application of a crude extract from Equisetum arvense
    • Graefe E.U., Veit M. Urinary metabolites of flavonoids and hydroxycinnamic acids in humans after application of a crude extract from Equisetum arvense. Phytomedicine 1999, 6(4):239-246.
    • (1999) Phytomedicine , vol.6 , Issue.4 , pp. 239-246
    • Graefe, E.U.1    Veit, M.2
  • 186
    • 3042542425 scopus 로고    scopus 로고
    • Molecular and cellular physiology of renal organic cation and anion transport
    • Wright S.H., Dantzler W.H. Molecular and cellular physiology of renal organic cation and anion transport. Physiol Rev 2004, 84(3):987-1049.
    • (2004) Physiol Rev , vol.84 , Issue.3 , pp. 987-1049
    • Wright, S.H.1    Dantzler, W.H.2
  • 187
    • 33644847684 scopus 로고    scopus 로고
    • Transporters as a determinant of drug clearance and tissue distribution
    • Shitara Y., Horie T., Sugiyama Y. Transporters as a determinant of drug clearance and tissue distribution. Eur J Pharm Sci 2006, 27(5):425-446.
    • (2006) Eur J Pharm Sci , vol.27 , Issue.5 , pp. 425-446
    • Shitara, Y.1    Horie, T.2    Sugiyama, Y.3
  • 188
    • 79952575127 scopus 로고    scopus 로고
    • Flavonoid conjugates interact with organic anion transporters (OATs) and attenuate cytotoxicity of adefovir mediated by organic anion transporter 1 (OAT1/SLC22A6)
    • Wong C.C., Botting N.P., Orfila C., Al-Maharik N., Williamson G. Flavonoid conjugates interact with organic anion transporters (OATs) and attenuate cytotoxicity of adefovir mediated by organic anion transporter 1 (OAT1/SLC22A6). Biochem Pharmacol 2011, 81(7):942-949.
    • (2011) Biochem Pharmacol , vol.81 , Issue.7 , pp. 942-949
    • Wong, C.C.1    Botting, N.P.2    Orfila, C.3    Al-Maharik, N.4    Williamson, G.5
  • 189
    • 34547189233 scopus 로고    scopus 로고
    • Interaction of positional isomers of quercetin glucuronides with the transporter ABCC2 (cMOAT, MRP2)
    • Williamson G., Aeberli I., Miguet L., Zhang Z., Sanchez M.B., Crespy V., et al. Interaction of positional isomers of quercetin glucuronides with the transporter ABCC2 (cMOAT, MRP2). Drug Metab Dispos 2007, 35(8):1262-1268.
    • (2007) Drug Metab Dispos , vol.35 , Issue.8 , pp. 1262-1268
    • Williamson, G.1    Aeberli, I.2    Miguet, L.3    Zhang, Z.4    Sanchez, M.B.5    Crespy, V.6
  • 190
    • 0037300834 scopus 로고    scopus 로고
    • Metabolism of quercetin-7- and quercetin-3-glucuronides by an in vitro hepatic model: the role of human beta-glucuronidase, sulfotransferase, catechol-O-methyltransferase and multi-resistant protein 2 (MRP2) in flavonoid metabolism
    • O'Leary K.A., Day A.J., Needs P.W., Mellon F.A., O'Brien N.M., Williamson G. Metabolism of quercetin-7- and quercetin-3-glucuronides by an in vitro hepatic model: the role of human beta-glucuronidase, sulfotransferase, catechol-O-methyltransferase and multi-resistant protein 2 (MRP2) in flavonoid metabolism. Biochem Pharmacol 2003, 65(3):479-491.
    • (2003) Biochem Pharmacol , vol.65 , Issue.3 , pp. 479-491
    • O'Leary, K.A.1    Day, A.J.2    Needs, P.W.3    Mellon, F.A.4    O'Brien, N.M.5    Williamson, G.6
  • 191
    • 70349647191 scopus 로고    scopus 로고
    • Allopurinol, rutin, and quercetin attenuate hyperuricemia and renal dysfunction in rats induced by fructose intake: renal organic ion transporter involvement
    • Hu Q.-H., Wang C., Li J.-M., Zhang D.-M., Kong L.-D. Allopurinol, rutin, and quercetin attenuate hyperuricemia and renal dysfunction in rats induced by fructose intake: renal organic ion transporter involvement. Am J Physiol Renal Physiol 2009, 297(4):1080-1091.
    • (2009) Am J Physiol Renal Physiol , vol.297 , Issue.4 , pp. 1080-1091
    • Hu, Q.-H.1    Wang, C.2    Li, J.-M.3    Zhang, D.-M.4    Kong, L.-D.5
  • 192
    • 0025039139 scopus 로고
    • Bilitranslocase localization and function in basolateral plasma membrane of renal proximal tubule in rat
    • Elias M.M., Lunazzi G.C., Passamonti S., Gazzin B., Miccio M., Stanta G., et al. Bilitranslocase localization and function in basolateral plasma membrane of renal proximal tubule in rat. Am J Physiol 1990, 259(4 Pt 2):559-564.
    • (1990) Am J Physiol , vol.259 , Issue.4 PART 2 , pp. 559-564
    • Elias, M.M.1    Lunazzi, G.C.2    Passamonti, S.3    Gazzin, B.4    Miccio, M.5    Stanta, G.6
  • 194
    • 7544245330 scopus 로고    scopus 로고
    • Effects of grapefruit juice on the multidrug transporter P-glycoprotein in the human proximal tubular cell line HK-2
    • Romiti N., Tramonti G., Donati A., Chieli E. Effects of grapefruit juice on the multidrug transporter P-glycoprotein in the human proximal tubular cell line HK-2. Life Sci 2004, 76(3):293-302.
    • (2004) Life Sci , vol.76 , Issue.3 , pp. 293-302
    • Romiti, N.1    Tramonti, G.2    Donati, A.3    Chieli, E.4
  • 195
    • 69949106198 scopus 로고    scopus 로고
    • Emerging significance of flavonoids as P-glycoprotein inhibitors in cancer chemotherapy
    • Bansal T., Jaggi M., Khar R., Talegaonkar S. Emerging significance of flavonoids as P-glycoprotein inhibitors in cancer chemotherapy. J Pharm Pharm Sci 2009, 12(1):46-78.
    • (2009) J Pharm Pharm Sci , vol.12 , Issue.1 , pp. 46-78
    • Bansal, T.1    Jaggi, M.2    Khar, R.3    Talegaonkar, S.4
  • 196
    • 13244258342 scopus 로고    scopus 로고
    • Transepithelial transport of microbial metabolites of quercetin in intestinal Caco-2 cell monolayers
    • Konishi Y. Transepithelial transport of microbial metabolites of quercetin in intestinal Caco-2 cell monolayers. J Agric Food Chem 2005, 53(3):601-607.
    • (2005) J Agric Food Chem , vol.53 , Issue.3 , pp. 601-607
    • Konishi, Y.1
  • 197
    • 51249090528 scopus 로고    scopus 로고
    • Pharmacokinetic interaction between the flavonoid luteolin and γ-hydroxybutyrate in rats: potential involvement of monocarboxylate transporters
    • Wang X., Wang Q., Morris M.E. Pharmacokinetic interaction between the flavonoid luteolin and γ-hydroxybutyrate in rats: potential involvement of monocarboxylate transporters. AAPS J 2008, 10(1):47-55.
    • (2008) AAPS J , vol.10 , Issue.1 , pp. 47-55
    • Wang, X.1    Wang, Q.2    Morris, M.E.3
  • 198
    • 3242875643 scopus 로고    scopus 로고
    • The flavone hispidulin, a benzodiazepine receptor ligand with positive allosteric properties, traverses the blood-brain barrier and exhibits anticonvulsive effects
    • Kavvadias D., Sand P., Youdim K.A., Qaiser M.Z., Rice-Evans C., Baur R., et al. The flavone hispidulin, a benzodiazepine receptor ligand with positive allosteric properties, traverses the blood-brain barrier and exhibits anticonvulsive effects. Br J Pharmacol 2004, 142(5):811-820.
    • (2004) Br J Pharmacol , vol.142 , Issue.5 , pp. 811-820
    • Kavvadias, D.1    Sand, P.2    Youdim, K.A.3    Qaiser, M.Z.4    Rice-Evans, C.5    Baur, R.6
  • 200
    • 77950672438 scopus 로고    scopus 로고
    • Xenobiotic metabolism and berry flavonoid transport across the blood-brain barrier
    • Milbury P.E., Kalt W. Xenobiotic metabolism and berry flavonoid transport across the blood-brain barrier. J Agric Food Chem 2010, 58(7):3950-3956.
    • (2010) J Agric Food Chem , vol.58 , Issue.7 , pp. 3950-3956
    • Milbury, P.E.1    Kalt, W.2
  • 201
    • 79952155958 scopus 로고    scopus 로고
    • Comparison of metabolic profiling of cyanidin-3-O-galactoside and extracts from blueberry in aged mice
    • Yang H., Pang W., Lu H., Cheng D., Yan X., Cheng Y., et al. Comparison of metabolic profiling of cyanidin-3-O-galactoside and extracts from blueberry in aged mice. J Agric Food Chem 2011, 59(5):2069-2076.
    • (2011) J Agric Food Chem , vol.59 , Issue.5 , pp. 2069-2076
    • Yang, H.1    Pang, W.2    Lu, H.3    Cheng, D.4    Yan, X.5    Cheng, Y.6
  • 202
    • 2342471420 scopus 로고    scopus 로고
    • The blood-brain barrier: an overview: structure, regulation, and clinical implications
    • Ballabh P., Braun A., Nedergaard M. The blood-brain barrier: an overview: structure, regulation, and clinical implications. Neurobiol Dis 2004, 16(1):1-13.
    • (2004) Neurobiol Dis , vol.16 , Issue.1 , pp. 1-13
    • Ballabh, P.1    Braun, A.2    Nedergaard, M.3
  • 203
    • 80053555632 scopus 로고    scopus 로고
    • Interplay of drug metabolizing CYP450 enzymes and ABC transporters in the blood-brain barrier
    • Decleves X., Jacob A., Yousif S., Shawahna R., Potin S., Scherrmann J.M. interplay of drug metabolizing CYP450 enzymes and ABC transporters in the blood-brain barrier. Curr Drug Metab 2011, 12(8):732-741.
    • (2011) Curr Drug Metab , vol.12 , Issue.8 , pp. 732-741
    • Decleves, X.1    Jacob, A.2    Yousif, S.3    Shawahna, R.4    Potin, S.5    Scherrmann, J.M.6
  • 205
    • 79952017177 scopus 로고    scopus 로고
    • Insights into the putative catechin and epicatechin transport across blood-brain barrier
    • Faria A., Pestana D., Teixeira D., Couraud P.O., Romero I., Weksler B., et al. Insights into the putative catechin and epicatechin transport across blood-brain barrier. Food Funct 2011, 2(1):39-44.
    • (2011) Food Funct , vol.2 , Issue.1 , pp. 39-44
    • Faria, A.1    Pestana, D.2    Teixeira, D.3    Couraud, P.O.4    Romero, I.5    Weksler, B.6
  • 207
    • 1242338756 scopus 로고    scopus 로고
    • Flavonoid permeability across an in situ model of the blood-brain barrier
    • Youdim K., Qaiser M., Begley D., Rice-Evans C., Abbott N. Flavonoid permeability across an in situ model of the blood-brain barrier. Free Radic Biol Med 2004, 36(5):592-604.
    • (2004) Free Radic Biol Med , vol.36 , Issue.5 , pp. 592-604
    • Youdim, K.1    Qaiser, M.2    Begley, D.3    Rice-Evans, C.4    Abbott, N.5
  • 208
  • 209
    • 84862951933 scopus 로고    scopus 로고
    • An in vitro transport model for rapid screening and predicting the permeability of candidate compounds at blood-brain barrier
    • Yang Z., Sun X., Mei C., Sun X., Liu X., Chang Q. An in vitro transport model for rapid screening and predicting the permeability of candidate compounds at blood-brain barrier. J Asian Nat Prod Res 2011, 13(12):1087-1097.
    • (2011) J Asian Nat Prod Res , vol.13 , Issue.12 , pp. 1087-1097
    • Yang, Z.1    Sun, X.2    Mei, C.3    Sun, X.4    Liu, X.5    Chang, Q.6
  • 210
    • 85057673954 scopus 로고    scopus 로고
    • Transport of flavonoids into the brain
    • CRC, L. Packer, H. Sies, M. Eggersdorfer, E. Cadenas (Eds.)
    • Milbury P.E. Transport of flavonoids into the brain. Micronutrients and brain health 2009, 265. CRC. L. Packer, H. Sies, M. Eggersdorfer, E. Cadenas (Eds.).
    • (2009) Micronutrients and brain health , pp. 265
    • Milbury, P.E.1
  • 211
    • 7444253369 scopus 로고    scopus 로고
    • Flavonoids and the brain: interactions at the blood-brain barrier and their physiological effects on the central nervous system
    • Youdim K., Shukitt-Hale B., Joseph J. Flavonoids and the brain: interactions at the blood-brain barrier and their physiological effects on the central nervous system. Free Radic Biol Med 2004, 37(11):1683-1693.
    • (2004) Free Radic Biol Med , vol.37 , Issue.11 , pp. 1683-1693
    • Youdim, K.1    Shukitt-Hale, B.2    Joseph, J.3
  • 212
    • 77953141219 scopus 로고    scopus 로고
    • ABC transporters and drug efflux at the blood-brain barrier
    • Shen S., Zhang W. ABC transporters and drug efflux at the blood-brain barrier. Rev Neurosci 2010, 21(1):29-53.
    • (2010) Rev Neurosci , vol.21 , Issue.1 , pp. 29-53
    • Shen, S.1    Zhang, W.2
  • 213
    • 0037427972 scopus 로고    scopus 로고
    • The superfamily of organic anion transporting polypeptides
    • Hagenbuch B., Meier P.J. The superfamily of organic anion transporting polypeptides. Biochim Biophys Acta 2003, 1609(1):1-18.
    • (2003) Biochim Biophys Acta , vol.1609 , Issue.1 , pp. 1-18
    • Hagenbuch, B.1    Meier, P.J.2
  • 215
    • 70350223814 scopus 로고    scopus 로고
    • Blood-brain barrier transporters and response to CNS-active drugs
    • Urquhart B.L., Kim R.B. Blood-brain barrier transporters and response to CNS-active drugs. Eur J Clin Pharmacol 2009, 65(11):1063-1070.
    • (2009) Eur J Clin Pharmacol , vol.65 , Issue.11 , pp. 1063-1070
    • Urquhart, B.L.1    Kim, R.B.2
  • 216
    • 0028825450 scopus 로고
    • Distribution of morphine 6-glucuronide and morphine across the blood-brain barrier in awake, freely moving rats investigated by in vivo microdialysis sampling
    • Aasmundstad T.A., Morland J., Paulsen R.E. Distribution of morphine 6-glucuronide and morphine across the blood-brain barrier in awake, freely moving rats investigated by in vivo microdialysis sampling. J Pharmacol Exp Ther 1995, 275(1):435-441.
    • (1995) J Pharmacol Exp Ther , vol.275 , Issue.1 , pp. 435-441
    • Aasmundstad, T.A.1    Morland, J.2    Paulsen, R.E.3
  • 217
    • 84857425602 scopus 로고    scopus 로고
    • The influence of active transport systems on morphine-6-glucuronide transport in MDCKII and MDCK-PGP cells
    • Sattari M., Routledge P., Mashayekhi S. The influence of active transport systems on morphine-6-glucuronide transport in MDCKII and MDCK-PGP cells. Daru 2011, 19(6):412-416.
    • (2011) Daru , vol.19 , Issue.6 , pp. 412-416
    • Sattari, M.1    Routledge, P.2    Mashayekhi, S.3
  • 218
    • 0141432124 scopus 로고    scopus 로고
    • Evidence for an active transport of morphine-6β-d-glucuronide but not P-glycoprotein-mediated at the blood-brain barrier
    • Bourasset F., Cisternino S., Temsamani J., Scherrmann J.M. Evidence for an active transport of morphine-6β-d-glucuronide but not P-glycoprotein-mediated at the blood-brain barrier. J Neurochem 2003, 86(6):1564-1567.
    • (2003) J Neurochem , vol.86 , Issue.6 , pp. 1564-1567
    • Bourasset, F.1    Cisternino, S.2    Temsamani, J.3    Scherrmann, J.M.4
  • 219
    • 12344337754 scopus 로고    scopus 로고
    • Localization of brain endothelial luminal and abluminal transporters with immunogold electron microscopy
    • Cornford E.M., Hyman S. Localization of brain endothelial luminal and abluminal transporters with immunogold electron microscopy. NeuroRx 2005, 2(1):27-43.
    • (2005) NeuroRx , vol.2 , Issue.1 , pp. 27-43
    • Cornford, E.M.1    Hyman, S.2
  • 220
    • 29244441701 scopus 로고    scopus 로고
    • ABCC drug efflux pumps and organic anion uptake transporters in human gliomas and the blood-tumor barrier
    • Bronger H., Konig J., Kopplow K., Steiner H.H., Ahmadi R., Herold-Mende C., et al. ABCC drug efflux pumps and organic anion uptake transporters in human gliomas and the blood-tumor barrier. Cancer Res 2005, 65(24):11419-11428.
    • (2005) Cancer Res , vol.65 , Issue.24 , pp. 11419-11428
    • Bronger, H.1    Konig, J.2    Kopplow, K.3    Steiner, H.H.4    Ahmadi, R.5    Herold-Mende, C.6
  • 221
    • 12344273724 scopus 로고    scopus 로고
    • Small molecular drug transfer across the blood-brain barrier via carrier-mediated transport systems
    • Tsuji A. Small molecular drug transfer across the blood-brain barrier via carrier-mediated transport systems. NeuroRx 2005, 2(1):54-62.
    • (2005) NeuroRx , vol.2 , Issue.1 , pp. 54-62
    • Tsuji, A.1
  • 222
    • 0035212257 scopus 로고    scopus 로고
    • Drug transporters in the central nervous system: brain barriers and brain parenchyma considerations
    • Lee G., Dallas S., Hong M., Bendayan R. Drug transporters in the central nervous system: brain barriers and brain parenchyma considerations. Pharmacol Rev 2001, 53(4):569-596.
    • (2001) Pharmacol Rev , vol.53 , Issue.4 , pp. 569-596
    • Lee, G.1    Dallas, S.2    Hong, M.3    Bendayan, R.4
  • 223
    • 0037113346 scopus 로고    scopus 로고
    • Localisation of breast cancer resistance protein in microvessel endothelium of human brain
    • Cooray H.C., Blackmore C.G., Maskell L., Barrand M.A. Localisation of breast cancer resistance protein in microvessel endothelium of human brain. Neuroreport 2002, 13(16):2059-2063.
    • (2002) Neuroreport , vol.13 , Issue.16 , pp. 2059-2063
    • Cooray, H.C.1    Blackmore, C.G.2    Maskell, L.3    Barrand, M.A.4
  • 224
    • 0642303659 scopus 로고    scopus 로고
    • The expression and functional characterization of ABCG2 in brain endothelial cells and vessels
    • Zhang W., Mojsilovic-Petrovic J., Andrade M.F., Zhang H., Ball M., Stanimirovic D.B. The expression and functional characterization of ABCG2 in brain endothelial cells and vessels. FASEB J 2003, 17(14):2085-2087.
    • (2003) FASEB J , vol.17 , Issue.14 , pp. 2085-2087
    • Zhang, W.1    Mojsilovic-Petrovic, J.2    Andrade, M.F.3    Zhang, H.4    Ball, M.5    Stanimirovic, D.B.6
  • 225
    • 70449687880 scopus 로고    scopus 로고
    • Interaction of benzopyranone derivatives and related compounds with human concentrative nucleoside transporters 1, 2 and 3 heterologously expressed in porcine PK15 nucleoside transporter deficient cells. Structure-activity relationships and determinants of transporter affinity and selectivity
    • Wang C., Pimple S., Buolamwini J.K. Interaction of benzopyranone derivatives and related compounds with human concentrative nucleoside transporters 1, 2 and 3 heterologously expressed in porcine PK15 nucleoside transporter deficient cells. Structure-activity relationships and determinants of transporter affinity and selectivity. Biochem Pharmacol 2010, 79(3):307-320.
    • (2010) Biochem Pharmacol , vol.79 , Issue.3 , pp. 307-320
    • Wang, C.1    Pimple, S.2    Buolamwini, J.K.3
  • 226
    • 72049124853 scopus 로고    scopus 로고
    • Expression of bilitranslocase in the vascular endothelium and its function as a flavonoid transporter
    • Maestro A., Terdoslavich M., Vanzo A., Kuku A., Tramer F., Nicolin V., et al. Expression of bilitranslocase in the vascular endothelium and its function as a flavonoid transporter. Cardiovasc Res 2010, 85(1):175-183.
    • (2010) Cardiovasc Res , vol.85 , Issue.1 , pp. 175-183
    • Maestro, A.1    Terdoslavich, M.2    Vanzo, A.3    Kuku, A.4    Tramer, F.5    Nicolin, V.6
  • 228
    • 79957850339 scopus 로고    scopus 로고
    • Exceptionally fast uptake and metabolism of cyanidin 3-glucoside by rat kidneys and liver
    • Vanzo A., Vrhovsek U., Tramer F., Mattivi F., Passamonti S. Exceptionally fast uptake and metabolism of cyanidin 3-glucoside by rat kidneys and liver. J Nat Prod 2011, 74(5):1049-1054.
    • (2011) J Nat Prod , vol.74 , Issue.5 , pp. 1049-1054
    • Vanzo, A.1    Vrhovsek, U.2    Tramer, F.3    Mattivi, F.4    Passamonti, S.5
  • 229
    • 11844253806 scopus 로고    scopus 로고
    • Flavonoid-serum albumin complexation: determination of binding constants and binding sites by fluorescence spectroscopy
    • Dufour C., Dangles O. Flavonoid-serum albumin complexation: determination of binding constants and binding sites by fluorescence spectroscopy. Biochim Biophys Acta 2005, 1721(1-3):164-173.
    • (2005) Biochim Biophys Acta , vol.1721 , Issue.1-3 , pp. 164-173
    • Dufour, C.1    Dangles, O.2
  • 230
    • 9244243170 scopus 로고    scopus 로고
    • Spectrophotometric and kinetic studies on the binding of the bioflavonoid quercetin to bovine serum albumin
    • Kitson T.M. Spectrophotometric and kinetic studies on the binding of the bioflavonoid quercetin to bovine serum albumin. Biosci Biotechnol Biochem 2004, 68(10):2165-2170.
    • (2004) Biosci Biotechnol Biochem , vol.68 , Issue.10 , pp. 2165-2170
    • Kitson, T.M.1
  • 231
    • 78649906350 scopus 로고    scopus 로고
    • Acute cardioprotective and cardiotoxic effects of bilberry anthocyanins in ischemia-reperfusion injury: beyond concentration-dependent antioxidant activity
    • Ziberna L., Lunder M., Moze S., Vanzo A., Tramer F., Passamonti S., et al. Acute cardioprotective and cardiotoxic effects of bilberry anthocyanins in ischemia-reperfusion injury: beyond concentration-dependent antioxidant activity. Cardiovasc Toxicol 2010, 10(4):283-294.
    • (2010) Cardiovasc Toxicol , vol.10 , Issue.4 , pp. 283-294
    • Ziberna, L.1    Lunder, M.2    Moze, S.3    Vanzo, A.4    Tramer, F.5    Passamonti, S.6
  • 232
    • 47949116376 scopus 로고    scopus 로고
    • Urinary excretion of 13 dietary flavonoids and phenolic acids in free-living healthy subjects - variability and possible use as biomarkers of polyphenol intake
    • Mennen L.I., Sapinho D., Ito H., Galan P., Hercberg S., Scalbert A. Urinary excretion of 13 dietary flavonoids and phenolic acids in free-living healthy subjects - variability and possible use as biomarkers of polyphenol intake. Eur J Clin Nutr 2008, 62(4):519-525.
    • (2008) Eur J Clin Nutr , vol.62 , Issue.4 , pp. 519-525
    • Mennen, L.I.1    Sapinho, D.2    Ito, H.3    Galan, P.4    Hercberg, S.5    Scalbert, A.6
  • 233
    • 79952012081 scopus 로고    scopus 로고
    • Conjugated quercetin glucuronides as bioactive metabolites and precursors of aglycone in vivo
    • Terao J., Murota K., Kawai Y. Conjugated quercetin glucuronides as bioactive metabolites and precursors of aglycone in vivo. Food Funct 2011, 2(1):11-17.
    • (2011) Food Funct , vol.2 , Issue.1 , pp. 11-17
    • Terao, J.1    Murota, K.2    Kawai, Y.3
  • 234
    • 84861456545 scopus 로고    scopus 로고
    • Synergy study of the inhibitory potential of red wine polyphenols on vascular smooth muscle cell proliferation
    • Kurin E., Atanasov A.G., Donath O., Heiss E.H., Dirsch V.M., Nagy M. Synergy study of the inhibitory potential of red wine polyphenols on vascular smooth muscle cell proliferation. Planta Med 2012, 78(8):772-778.
    • (2012) Planta Med , vol.78 , Issue.8 , pp. 772-778
    • Kurin, E.1    Atanasov, A.G.2    Donath, O.3    Heiss, E.H.4    Dirsch, V.M.5    Nagy, M.6
  • 235
    • 84872805497 scopus 로고    scopus 로고
    • The flavonoids diosmetin and luteolin exert synergistic cytostatic effects in human hepatoma HepG2 cells via CYP1A-catalyzed metabolism, activation of JNK and ERK and P53/P21 up-regulation
    • Androutsopoulos V.P., Spandidos D.A. The flavonoids diosmetin and luteolin exert synergistic cytostatic effects in human hepatoma HepG2 cells via CYP1A-catalyzed metabolism, activation of JNK and ERK and P53/P21 up-regulation. J Nutr Biochem 2013, 24(2):496-504.
    • (2013) J Nutr Biochem , vol.24 , Issue.2 , pp. 496-504
    • Androutsopoulos, V.P.1    Spandidos, D.A.2
  • 236
    • 84864424839 scopus 로고    scopus 로고
    • In vitro and in vivo evaluation of a novel antiherpetic flavonoid, 4'-phenylflavone, and its synergistic actions with acyclovir
    • Hayashi K., Iinuma M., Sasaki K., Hayashi T. In vitro and in vivo evaluation of a novel antiherpetic flavonoid, 4'-phenylflavone, and its synergistic actions with acyclovir. Arch Virol 2012, 157(8):1489-1498.
    • (2012) Arch Virol , vol.157 , Issue.8 , pp. 1489-1498
    • Hayashi, K.1    Iinuma, M.2    Sasaki, K.3    Hayashi, T.4
  • 238
    • 77956634425 scopus 로고    scopus 로고
    • Hormesis and synergy: pathways and mechanisms of quercetin in cancer prevention and management
    • Vargas A.J., Burd R. Hormesis and synergy: pathways and mechanisms of quercetin in cancer prevention and management. Nutr Rev 2010, 68(7):418-428.
    • (2010) Nutr Rev , vol.68 , Issue.7 , pp. 418-428
    • Vargas, A.J.1    Burd, R.2
  • 240
    • 38749131263 scopus 로고    scopus 로고
    • Effects of dietary polyphenols on gene expression in human vascular endothelial cells
    • Nicholson S.K., Tucker G.A., Brameld J.M. Effects of dietary polyphenols on gene expression in human vascular endothelial cells. Proc Nutr Soc 2008, 67(1):42-47.
    • (2008) Proc Nutr Soc , vol.67 , Issue.1 , pp. 42-47
    • Nicholson, S.K.1    Tucker, G.A.2    Brameld, J.M.3
  • 241
    • 84863508355 scopus 로고    scopus 로고
    • Age-related changes in cellular protection, purification, and inflammation-related gene expression: role of dietary phytonutrients
    • Mastaloudis A., Wood S.M. Age-related changes in cellular protection, purification, and inflammation-related gene expression: role of dietary phytonutrients. Ann NY Acad Sci 2012, 1259:112-120.
    • (2012) Ann NY Acad Sci , vol.1259 , pp. 112-120
    • Mastaloudis, A.1    Wood, S.M.2
  • 242
    • 33646179260 scopus 로고    scopus 로고
    • Upregulation of heme oxygenase-1 by epigallocatechin-3-gallate via the phosphatidylinositol 3-kinase/Akt and ERK pathways
    • Wu C.C., Hsu M.C., Hsieh C.W., Lin J.B., Lai P.H., Wung B.S. Upregulation of heme oxygenase-1 by epigallocatechin-3-gallate via the phosphatidylinositol 3-kinase/Akt and ERK pathways. Life Sci 2006, 78(25):2889-2897.
    • (2006) Life Sci , vol.78 , Issue.25 , pp. 2889-2897
    • Wu, C.C.1    Hsu, M.C.2    Hsieh, C.W.3    Lin, J.B.4    Lai, P.H.5    Wung, B.S.6
  • 243
    • 84872334653 scopus 로고    scopus 로고
    • Drug-grapefruit juice interactions
    • Pirmohamed M. Drug-grapefruit juice interactions. BMJ 2013, 346:f1.
    • (2013) BMJ , vol.346
    • Pirmohamed, M.1
  • 244
    • 74049143120 scopus 로고    scopus 로고
    • Modulation of the activity of ABC transporters (P-glycoprotein, MRP2, BCRP) by flavonoids and drug response
    • Alvarez A.I., Real R., Perez M., Mendoza G., Prieto J.G., Merino G. Modulation of the activity of ABC transporters (P-glycoprotein, MRP2, BCRP) by flavonoids and drug response. J Pharm Sci 2010, 99(2):598-617.
    • (2010) J Pharm Sci , vol.99 , Issue.2 , pp. 598-617
    • Alvarez, A.I.1    Real, R.2    Perez, M.3    Mendoza, G.4    Prieto, J.G.5    Merino, G.6
  • 245
    • 0036159433 scopus 로고    scopus 로고
    • Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine
    • Dresser G.K., Bailey D.G., Leake B.F., Schwarz U.I., Dawson P.A., Freeman D.J., et al. Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine. Clin Pharmacol Ther 2002, 71(1):11-20.
    • (2002) Clin Pharmacol Ther , vol.71 , Issue.1 , pp. 11-20
    • Dresser, G.K.1    Bailey, D.G.2    Leake, B.F.3    Schwarz, U.I.4    Dawson, P.A.5    Freeman, D.J.6
  • 246
    • 0032793959 scopus 로고    scopus 로고
    • OATP and P-glycoprotein transporters mediate the cellular uptake and excretion of fexofenadine
    • Cvetkovic M., Leake B., Fromm M.F., Wilkinson G.R., Kim R.B. OATP and P-glycoprotein transporters mediate the cellular uptake and excretion of fexofenadine. Drug Metab Dispos 1999, 27(8):866-871.
    • (1999) Drug Metab Dispos , vol.27 , Issue.8 , pp. 866-871
    • Cvetkovic, M.1    Leake, B.2    Fromm, M.F.3    Wilkinson, G.R.4    Kim, R.B.5
  • 247
    • 33947420519 scopus 로고    scopus 로고
    • Naringin is a major and selective clinical inhibitor of organic anion-transporting polypeptide 1A2 (OATP1A2) in grapefruit juice
    • Bailey D.G., Dresser G.K., Leake B.F., Kim R.B. Naringin is a major and selective clinical inhibitor of organic anion-transporting polypeptide 1A2 (OATP1A2) in grapefruit juice. Clin Pharmacol Ther 2007, 81(4):495-502.
    • (2007) Clin Pharmacol Ther , vol.81 , Issue.4 , pp. 495-502
    • Bailey, D.G.1    Dresser, G.K.2    Leake, B.F.3    Kim, R.B.4
  • 248
    • 68849107630 scopus 로고    scopus 로고
    • Short-term effect of quercetin on the pharmacokinetics of fexofenadine, a substrate of P-glycoprotein, in healthy volunteers
    • Kim K.A., Park P.W., Park J.Y. Short-term effect of quercetin on the pharmacokinetics of fexofenadine, a substrate of P-glycoprotein, in healthy volunteers. Eur J Clin Pharmacol 2009, 65(6):609-614.
    • (2009) Eur J Clin Pharmacol , vol.65 , Issue.6 , pp. 609-614
    • Kim, K.A.1    Park, P.W.2    Park, J.Y.3
  • 249
    • 15544362234 scopus 로고    scopus 로고
    • Effect of quercetin on the pharmacokinetics of oral cyclosporine
    • Choi J.S., Choi B.C., Choi K.E. Effect of quercetin on the pharmacokinetics of oral cyclosporine. Am J Health Syst Pharm 2004, 61(22):2406-2409.
    • (2004) Am J Health Syst Pharm , vol.61 , Issue.22 , pp. 2406-2409
    • Choi, J.S.1    Choi, B.C.2    Choi, K.E.3
  • 250
    • 0029055363 scopus 로고
    • Disposition of intravenous and oral cyclosporine after administration with grapefruit juice
    • Ducharme M.P., Warbasse L.H., Edwards D.J. Disposition of intravenous and oral cyclosporine after administration with grapefruit juice. Clin Pharmacol Ther 1995, 57(5):485-491.
    • (1995) Clin Pharmacol Ther , vol.57 , Issue.5 , pp. 485-491
    • Ducharme, M.P.1    Warbasse, L.H.2    Edwards, D.J.3
  • 251
    • 1342347958 scopus 로고    scopus 로고
    • Study on the influence of silymarin pretreatment on metabolism and disposition of metronidazole
    • Rajnarayana K., Reddy M.S., Vidyasagar J., Krishna D.R. Study on the influence of silymarin pretreatment on metabolism and disposition of metronidazole. Arzneimittelforschung 2004, 54(2):109-113.
    • (2004) Arzneimittelforschung , vol.54 , Issue.2 , pp. 109-113
    • Rajnarayana, K.1    Reddy, M.S.2    Vidyasagar, J.3    Krishna, D.R.4
  • 252
    • 84877034928 scopus 로고    scopus 로고
    • Pharmacokinetic interaction study between quercetin and valsartan in rats and in vitro models
    • Challa V.R., Ravindra Babu P., Challa S.R., Johnson B., Maheswari C. Pharmacokinetic interaction study between quercetin and valsartan in rats and in vitro models. Drug Dev Ind Pharm 2013, 39(6):865-872.
    • (2013) Drug Dev Ind Pharm , vol.39 , Issue.6 , pp. 865-872
    • Challa, V.R.1    Ravindra Babu, P.2    Challa, S.R.3    Johnson, B.4    Maheswari, C.5
  • 253
    • 10044220716 scopus 로고    scopus 로고
    • The effect of quercetin on the pharmacokinetics of verapamil and its major metabolite, norverapamil, in rabbits
    • Choi J.S., Han H.K. The effect of quercetin on the pharmacokinetics of verapamil and its major metabolite, norverapamil, in rabbits. J Pharm Pharmacol 2004, 56(12):1537-1542.
    • (2004) J Pharm Pharmacol , vol.56 , Issue.12 , pp. 1537-1542
    • Choi, J.S.1    Han, H.K.2
  • 254
    • 0347510572 scopus 로고    scopus 로고
    • Lethal quercetin-digoxin interaction in pigs
    • Wang Y.H., Chao P.D., Hsiu S.L., Wen K.C., Hou Y.C. Lethal quercetin-digoxin interaction in pigs. Life Sci 2004, 74(10):1191-1197.
    • (2004) Life Sci , vol.74 , Issue.10 , pp. 1191-1197
    • Wang, Y.H.1    Chao, P.D.2    Hsiu, S.L.3    Wen, K.C.4    Hou, Y.C.5
  • 255
    • 1842789744 scopus 로고    scopus 로고
    • Enhanced bioavailability of paclitaxel after oral coadministration with flavone in rats
    • Choi J.S., Choi H.K., Shin S.C. Enhanced bioavailability of paclitaxel after oral coadministration with flavone in rats. Int J Pharm 2004, 275(1-2):165-170.
    • (2004) Int J Pharm , vol.275 , Issue.1-2 , pp. 165-170
    • Choi, J.S.1    Choi, H.K.2    Shin, S.C.3
  • 256
    • 0037465616 scopus 로고    scopus 로고
    • Enhancement of moxidectin bioavailability in lamb by a natural flavonoid: quercetin
    • Dupuy J., Larrieu G., Sutra J.F., Lespine A., Alvinerie M. Enhancement of moxidectin bioavailability in lamb by a natural flavonoid: quercetin. Vet Parasitol 2003, 112(4):337-347.
    • (2003) Vet Parasitol , vol.112 , Issue.4 , pp. 337-347
    • Dupuy, J.1    Larrieu, G.2    Sutra, J.F.3    Lespine, A.4    Alvinerie, M.5
  • 257
    • 19344368397 scopus 로고    scopus 로고
    • Enhanced diltiazem bioavailability after oral administration of diltiazem with quercetin to rabbits
    • Choi J.S., Li X. Enhanced diltiazem bioavailability after oral administration of diltiazem with quercetin to rabbits. Int J Pharm 2005, 297(1-2):1-8.
    • (2005) Int J Pharm , vol.297 , Issue.1-2 , pp. 1-8
    • Choi, J.S.1    Li, X.2
  • 258
    • 13844256394 scopus 로고    scopus 로고
    • Enhanced paclitaxel bioavailability after oral coadministration of paclitaxel prodrug with naringin to rats
    • Choi J.S., Shin S.C. Enhanced paclitaxel bioavailability after oral coadministration of paclitaxel prodrug with naringin to rats. Int J Pharm 2005, 292(1-2):149-156.
    • (2005) Int J Pharm , vol.292 , Issue.1-2 , pp. 149-156
    • Choi, J.S.1    Shin, S.C.2
  • 259
    • 34248512624 scopus 로고    scopus 로고
    • Effect of genistein on the pharmacokinetics of paclitaxel administered orally or intravenously in rats
    • Li X., Choi J.S. Effect of genistein on the pharmacokinetics of paclitaxel administered orally or intravenously in rats. Int J Pharm 2007, 337(1-2):188-193.
    • (2007) Int J Pharm , vol.337 , Issue.1-2 , pp. 188-193
    • Li, X.1    Choi, J.S.2
  • 260
    • 33846464175 scopus 로고    scopus 로고
    • Effects of the flavonoid chrysin on nitrofurantoin pharmacokinetics in rats: potential involvement of ABCG2
    • Wang X., Morris M.E. Effects of the flavonoid chrysin on nitrofurantoin pharmacokinetics in rats: potential involvement of ABCG2. Drug Metab Dispos 2007, 35(2):268-274.
    • (2007) Drug Metab Dispos , vol.35 , Issue.2 , pp. 268-274
    • Wang, X.1    Morris, M.E.2
  • 261
    • 0345974462 scopus 로고    scopus 로고
    • Transport of SN-38 by the wild type of human ABC transporter ABCG2 and its inhibition by quercetin, a natural flavonoid
    • Yoshikawa M., Ikegami Y., Sano K., Yoshida H., Mitomo H., Sawada S., et al. Transport of SN-38 by the wild type of human ABC transporter ABCG2 and its inhibition by quercetin, a natural flavonoid. J Exp Ther Oncol 2004, 4(1):25-35.
    • (2004) J Exp Ther Oncol , vol.4 , Issue.1 , pp. 25-35
    • Yoshikawa, M.1    Ikegami, Y.2    Sano, K.3    Yoshida, H.4    Mitomo, H.5    Sawada, S.6
  • 263
    • 75749153639 scopus 로고    scopus 로고
    • The 'ins' and 'outs' of flavonoid transport
    • Zhao J., Dixon R.A. The 'ins' and 'outs' of flavonoid transport. Trends Plant Sci 2010, 15(2):72-80.
    • (2010) Trends Plant Sci , vol.15 , Issue.2 , pp. 72-80
    • Zhao, J.1    Dixon, R.A.2
  • 264
    • 84874688353 scopus 로고    scopus 로고
    • The promiscuous binding of pharmaceutical drugs and their transporter-mediated uptake into cells: what we (need to) know and how we can do so
    • Kell D.B., Dobson P.D., Bilsland E., Oliver S.G. The promiscuous binding of pharmaceutical drugs and their transporter-mediated uptake into cells: what we (need to) know and how we can do so. Drug Discov Today 2013, 18(5-6):218-239.
    • (2013) Drug Discov Today , vol.18 , Issue.5-6 , pp. 218-239
    • Kell, D.B.1    Dobson, P.D.2    Bilsland, E.3    Oliver, S.G.4
  • 265
    • 40049110714 scopus 로고    scopus 로고
    • Carrier-mediated cellular uptake of pharmaceutical drugs: an exception or the rule?
    • Dobson P.D., Kell D.B. Carrier-mediated cellular uptake of pharmaceutical drugs: an exception or the rule?. Nat Rev Drug Discov 2008, 7(3):205-220.
    • (2008) Nat Rev Drug Discov , vol.7 , Issue.3 , pp. 205-220
    • Dobson, P.D.1    Kell, D.B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.