Absolute immunoquantification of the expression of ABC transporters P-glycoprotein, breast cancer resistance protein and multidrug resistance-associated protein 2 in human liver and duodenum

Biochemical Pharmacology

Volumn 83, Issue 2, 2012, Pages 279-285

  Tucker, Theodora G H A ^a   Milne, Alison M ^a   Fournel Gigleux, Sylvie ^a,b   Fenner, Katherine S ^c,d   Coughtrie, Michael W H ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b UNIVERSITÉ DE LORRAINE   (France)

^c PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

^d ASTRAZENECA   (United Kingdom)

Author keywords

BCRP; Drug transporters; Immunoquantification; MRP2; P glycoprotein

Indexed keywords

ABC TRANSPORTER; BREAST CANCER RESISTANCE PROTEIN; GLYCOPROTEIN P; MEMBRANE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 2; NUCLEASE S1; RECOMBINANT PROTEIN; RIBONUCLEASE;

ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG ELIMINATION; DUODENUM; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOASSAY; IMMUNOQUANTIFICATION; INDIVIDUALITY; LIVER; MUCOSA; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN QUALITY;

ATP-BINDING CASSETTE TRANSPORTERS; DUODENUM; GENE EXPRESSION REGULATION; HEK293 CELLS; HUMANS; IMMUNOBLOTTING; LIVER; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; NEOPLASM PROTEINS; P-GLYCOPROTEIN; PEPTIDE FRAGMENTS; PREDICTIVE VALUE OF TESTS; REPRODUCIBILITY OF RESULTS; RIBONUCLEASE, PANCREATIC;

EID: 83955163683     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2011.10.017     Document Type: Article

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