Transport of SN-38 by the Wild Type of Human ABC Transporter ABCG2 and Its Inhibition by Quercetin, a Natural Flavonoid

Journal of Experimental Therapeutics and Oncology

Volumn 4, Issue 1, 2004, Pages 25-35

  Yoshikawa, Megumi ^a,b   Ikegami, Yoji ^b   Sano, Kazumi ^b   Yoshida, Hisahiro ^b   Mitomo, Hideyuki ^a   Sawada, Seigo ^c   Ishikawa, Toshihisa ^a  

^a TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^b MEIJI PHARMACEUTICAL UNIVERSITY   (Japan)

^c YAKULT CENTRAL INSTITUTE FOR MICROBIOLOGICAL RESEARCH   (Japan)

Author keywords

ABC transporter; ABCG2; BCRP; Flavonoid; Irinotecan; Multidrug resistance

Indexed keywords

7 ETHYL 10 HYDROXYCAMPTOTHECIN; ABC TRANSPORTER; ADENOSINE TRIPHOSPHATE; ANTINEOPLASTIC AGENT; ARGININE; BREAST CANCER RESISTANCE PROTEIN; CAMPTOTHECIN DERIVATIVE; CARBOXYLIC ACID; CATECHIN; CISPLATIN; COMPLEMENTARY DNA; DAUNORUBICIN; DOXORUBICIN; EPIGALLOCATECHIN GALLATE; ETOPOSIDE; FLAVONOID; GLUCURONIDE; GLYCINE; IRINOTECAN; LACTONE; METHOTREXATE; MITOMYCIN C; MITOXANTRONE; PACLITAXEL; PROTEIN INHIBITOR; QUERCETIN; THEAFLAVIN; THEAFLAVIN 3,3' DIGALLATE; THREONINE; VINCRISTINE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; DNA TRANSFECTION; DRUG INHIBITION; DRUG SCREENING; DRUG TRANSPORT; ENZYME INHIBITION; HUMAN; HUMAN CELL; MEMBRANE VESICLE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCREENING; TRANSPORT KINETICS; TUMOR GROWTH;

ADENOSINE TRIPHOSPHATE; ANTINEOPLASTIC AGENTS, PHYTOGENIC; ATP-BINDING CASSETTE TRANSPORTERS; BIOLOGICAL TRANSPORT; CAMPTOTHECIN; CELL MEMBRANE; CELLS, CULTURED; DRUG RESISTANCE; GLUCURONIDES; HUMANS; MUTATION; NEOPLASM PROTEINS; QUERCETIN;

EID: 0345974462     PISSN: 13594117     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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