An in vitro transport model for rapid screening and predicting the permeability of candidate compounds at blood-brain barrier

Journal of Asian Natural Products Research

Volumn 13, Issue 12, 2011, Pages 1087-1097

  Yang, Zhi Hong ^a,b   Sun, Xiao ^a   Mei, Chao ^a   Sun, Xiao Bo ^a   Liu, Xiao Dong ^b   Chang, Qi ^a  

^a INSTITUTE OF MEDICINAL PLANT DEVELOPMENT   (China)

^b CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Blood brain barrier; Candidate compounds screening; P glycoprotein; Permeation model

Indexed keywords

CYCLOSPORIN A; GLYCOPROTEIN P; NARINGENIN; QUERCETIN; RHODAMINE 123; RUTOSIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOLOGICAL MODEL; BLOOD BRAIN BARRIER; CELL TRANSPORT; ELECTRIC RESISTANCE; ENDOTHELIUM CELL; IN VITRO STUDY; MICROPORE FILTER; NEWBORN; NONHUMAN; PERMEABILITY BARRIER; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; SCREENING TEST; TRANSENDOTHELIAL ELECTRICAL RESISTANCE; WESTERN BLOTTING;

ANIMALS; BIOLOGICAL TRANSPORT; BLOOD-BRAIN BARRIER; BRAIN; FLAVANONES; MALE; MODELS, BIOLOGICAL; P-GLYCOPROTEIN; QUERCETIN; RATS; RHODAMINE 123; RUTIN;

RATTUS;

EID: 84862951933     PISSN: 10286020     EISSN: 14772213     Source Type: Journal    
DOI: 10.1080/10286020.2011.599958     Document Type: Article

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