-
1
-
-
0030098277
-
Polyspecific drug and steroid clearance by an organic anion transporter of mammalian liver
-
Bossuyt X, Müller M, Hagenbuch B and Meier PJ (1996) Polyspecific drug and steroid clearance by an organic anion transporter of mammalian liver. J Phamacol Exp Ther 276:891-896.
-
(1996)
J Phamacol Exp Ther
, vol.276
, pp. 891-896
-
-
Bossuyt, X.1
Müller, M.2
Hagenbuch, B.3
Meier, P.J.4
-
2
-
-
0029022589
-
Identification of a sister gene to p-glycoprotein
-
Childs S, Yeh RL, Georges E and Ling V (1995) Identification of a sister gene to p-glycoprotein. Cancer Res 55:2029-2034.
-
(1995)
Cancer Res
, vol.55
, pp. 2029-2034
-
-
Childs, S.1
Yeh, R.L.2
Georges, E.3
Ling, V.4
-
3
-
-
0027095653
-
Overexpression of a transporter gene in a multidrugresistant human lung cancer cell line
-
Cole SPC, Bhardwaj G, Gerlach JH, Mackie JE, Grant CE, Almquist KC, Stewart AJ, Kurz EU, Duncan AMV and Deeley HG (1992) Overexpression of a transporter gene in a multidrugresistant human lung cancer cell line. Science (Wash DC) 258:1650-1654.
-
(1992)
Science (Wash DC)
, vol.258
, pp. 1650-1654
-
-
Cole, S.P.C.1
Bhardwaj, G.2
Gerlach, J.H.3
Mackie, J.E.4
Grant, C.E.5
Almquist, K.C.6
Stewart, A.J.7
Kurz, E.U.8
Duncan, A.M.V.9
Deeley, H.G.10
-
4
-
-
15844387507
-
The peptide-based thrombin inhibitor CRC 220 is a new substrate of the basolateral rat liver organic anion-transporting polypeptide
-
Eckhardt U, Horz JA, Petzinger E, Stüber W, Reers M, Dickneite G, Daniel H, Wagener M, Hagenbuch B, Stieger B and Meier PJ (1996) The peptide-based thrombin inhibitor CRC 220 is a new substrate of the basolateral rat liver organic anion-transporting polypeptide. Hepatology 24:380-384.
-
(1996)
Hepatology
, vol.24
, pp. 380-384
-
-
Eckhardt, U.1
Horz, J.A.2
Petzinger, E.3
Stüber, W.4
Reers, M.5
Dickneite, G.6
Daniel, H.7
Wagener, M.8
Hagenbuch, B.9
Stieger, B.10
Meier, P.J.11
-
5
-
-
0033514320
-
Inhibition of P-glycoprotein-mediated drug transport: A unifying mechanism to explain the interaction between digoxin and quinidine
-
Fromm MF, Kim RB, Stein CM, Wilkinson GR and Roden DM (1999) Inhibition of P-glycoprotein-mediated drug transport: A unifying mechanism to explain the interaction between digoxin and quinidine. Circulation 99:552-557.
-
(1999)
Circulation
, vol.99
, pp. 552-557
-
-
Fromm, M.F.1
Kim, R.B.2
Stein, C.M.3
Wilkinson, G.R.4
Roden, D.M.5
-
6
-
-
0032540277
-
The sister of P-glycoprotein represents the canalicular bile salt export pump of mammalian liver
-
Gerloff T, Stieger B, Hagenbuch B, Madon J, Landmann L, Roth J, Hofmann AF and Meier PJ (1998) The sister of P-glycoprotein represents the canalicular bile salt export pump of mammalian liver. J Biol Chem 273:10046-10050.
-
(1998)
J Biol Chem
, vol.273
, pp. 10046-10050
-
-
Gerloff, T.1
Stieger, B.2
Hagenbuch, B.3
Madon, J.4
Landmann, L.5
Roth, J.6
Hofmann, A.F.7
Meier, P.J.8
-
8
-
-
0032518290
-
The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors
-
Kim RB, Fromm MF, Wandel C, Leake B, Wood AJJ, Roden DM and Wilkinson GR (1998) The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors. J Clin Invest 101:289-294.
-
(1998)
J Clin Invest
, vol.101
, pp. 289-294
-
-
Kim, R.B.1
Fromm, M.F.2
Wandel, C.3
Leake, B.4
Wood, A.J.J.5
Roden, D.M.6
Wilkinson, G.R.7
-
9
-
-
0032907322
-
Interrelationship between substrates and inhibitors of human CYP3A and P-glycoprotein
-
Kim RB, Wandel C, Leake B, Cvetkovic M, Fromm MF, Dempsey PJ, Roden MM, Belas F, Chaudhary AK, Roden DM, Wood AJJ and Wilkinson GR (1999) Interrelationship between substrates and inhibitors of human CYP3A and P-glycoprotein. Pharm Res 16:408-414.
-
(1999)
Pharm Res
, vol.16
, pp. 408-414
-
-
Kim, R.B.1
Wandel, C.2
Leake, B.3
Cvetkovic, M.4
Fromm, M.F.5
Dempsey, P.J.6
Roden, M.M.7
Belas, F.8
Chaudhary, A.K.9
Roden, D.M.10
Wood, A.J.J.11
Wilkinson, G.R.12
-
10
-
-
0030841332
-
Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines
-
Kool M, de Haas M, Scheffer GL, Scheper RJ, van Eijk MJ, Juijn JA, Baas F and Borst P (1997) Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines. Cancer Res 57:3537-3547.
-
(1997)
Cancer Res
, vol.57
, pp. 3537-3547
-
-
Kool, M.1
De Haas, M.2
Scheffer, G.L.3
Scheper, R.J.4
Van Eijk, M.J.5
Juijn, J.A.6
Baas, F.7
Borst, P.8
-
11
-
-
0029091022
-
Molecular and functional characterization of an organic anion transporting polypeptide cloned from human liver
-
Kullak-Ublick G-A, Hagenbuch B, Stieger B, Schteingart CD, Hoffmann AF, Wolkoff AW and Meier PJ (1995) Molecular and functional characterization of an organic anion transporting polypeptide cloned from human liver. Gastroenterology 109:1274-1284.
-
(1995)
Gastroenterology
, vol.109
, pp. 1274-1284
-
-
Kullak-Ublick, G.-A.1
Hagenbuch, B.2
Stieger, B.3
Schteingart, C.D.4
Hoffmann, A.F.5
Wolkoff, A.W.6
Meier, P.J.7
-
12
-
-
0029013159
-
P-glycoprotein and pharmacokinetics
-
Levêque D and Jehl F (1995) P-glycoprotein and pharmacokinetics. Anticancer Res 15:331-336.
-
(1995)
Anticancer Res
, vol.15
, pp. 331-336
-
-
Levêque, D.1
Jehl, F.2
-
13
-
-
0000096993
-
Mass balance and pharmacokinetics of MDL 16455A in healthy male volunteers
-
Lippert C, Ling J, Brown P, Burmaster S, Eller M, Cheng L, Thompson R and Weir S (1995) Mass balance and pharmacokinetics of MDL 16455A in healthy male volunteers. Pharm Res 12:S390.
-
(1995)
Pharm Res
, vol.12
-
-
Lippert, C.1
Ling, J.2
Brown, P.3
Burmaster, S.4
Eller, M.5
Cheng, L.6
Thompson, R.7
Weir, S.8
-
15
-
-
0029860174
-
Substantial excretion of digoxin via the intestinal mucosa and prevention of long-term digoxin accumulation in the brain by the mdrla P-glycoprotein
-
Mayer U, Wagenaar E, Beijnen JH, Smit JW, Meijer DKF, van Asperen J, Borst P and Schinkel AH (1996) Substantial excretion of digoxin via the intestinal mucosa and prevention of long-term digoxin accumulation in the brain by the mdrla P-glycoprotein. Br J Pharmacol 119:1038-1044.
-
(1996)
Br J Pharmacol
, vol.119
, pp. 1038-1044
-
-
Mayer, U.1
Wagenaar, E.2
Beijnen, J.H.3
Smit, J.W.4
Meijer, D.K.F.5
Van Asperen, J.6
Borst, P.7
Schinkel, A.H.8
-
16
-
-
0030886124
-
Isolation of a multispecific organic anion and cardiac glycoside transporter from rat brain
-
Noé B, Hagenbuch B, Stieger B and Meier PJ (1997) Isolation of a multispecific organic anion and cardiac glycoside transporter from rat brain. Proc Natl Acad Sci USA 94:10346-10350.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 10346-10350
-
-
Noé, B.1
Hagenbuch, B.2
Stieger, B.3
Meier, P.J.4
-
18
-
-
0028229150
-
Disruption of the mouse mdrla P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs
-
Schinkel AH, Smit JJM, van Tellingen O, Beijnen JH, Wagenaar E, van Deemter L, Mol CAAM, van der Valk MA, Robanus-Maandag EC, te Riele HPJ, Berns AJM and Borst P (1994) Disruption of the mouse mdrla P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs. Cell 77:491-502.
-
(1994)
Cell
, vol.77
, pp. 491-502
-
-
Schinkel, A.H.1
Smit, J.J.M.2
Van Tellingen, O.3
Beijnen, J.H.4
Wagenaar, E.5
Van Deemter, L.6
Mol, C.A.A.M.7
Van Der Valk, M.A.8
Robanus-Maandag, E.C.9
Te Riele, H.P.J.10
Berns, A.J.M.11
Borst, P.12
-
19
-
-
0029892497
-
P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs
-
Schinkel AH, Wagenaar E, Mol CAAM and van Deemter L (1996) P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs. J Clin Invest 97:2517-2524.
-
(1996)
J Clin Invest
, vol.97
, pp. 2517-2524
-
-
Schinkel, A.H.1
Wagenaar, E.2
Mol, C.A.A.M.3
Van Deemter, L.4
-
20
-
-
0028825399
-
Absence of the mdrla P-glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A
-
Schinkel AH, Wagenaar E, van Deemter L, Mol CAAM and Borst P (1995) Absence of the mdrla P-glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A. J Clin Invest 96:1698-1705.
-
(1995)
J Clin Invest
, vol.96
, pp. 1698-1705
-
-
Schinkel, A.H.1
Wagenaar, E.2
Van Deemter, L.3
Mol, C.A.A.M.4
Borst, P.5
-
22
-
-
12644278301
-
Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine
-
Sparreboom A, van Asperen J, Mayer U, Schinkel AH, Smit JW, Meijer DKF, Borst P, Nooijen WJ, Beijnen JH and van Tellingen O (1997) Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine. Proc Natl Acad Sci USA 94:2031-2035.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 2031-2035
-
-
Sparreboom, A.1
Van Asperen, J.2
Mayer, U.3
Schinkel, A.H.4
Smit, J.W.5
Meijer, D.K.F.6
Borst, P.7
Nooijen, W.J.8
Beijnen, J.H.9
Van Tellingen, O.10
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