Structure-activity relationships of the inhibitory effects of flavonoids on P-glycoprotein-mediated transport in KB-C2 cells

Biological and Pharmaceutical Bulletin

Volumn 28, Issue 12, 2005, Pages 2274-2278

  Kitagawa, Shuji ^a   Nabekura, Tomohiro ^a   Takahashi, Tomoharu ^a   Nakamura, Yutaka ^a   Sakamoto, Hiromi ^a   Tano, Hiromi ^a   Hirai, Midori ^a   Tsukahara, Go ^a  

^a NIIGATA UNIVERSITY OF PHARMACY AND APPLIED LIFE SCIENCES   (Japan)

Author keywords

Flavonoid; KB C2 cell; P glycoprotein; Partition coefficient

Indexed keywords

BAICALEIN; DAUNORUBICIN; EPIGALLOCATECHIN GALLATE; FISETIN; FLAVONOID; GLYCOPROTEIN P; HYDROXYL GROUP; KAEMPFEROL; MORIN; MYRICETIN; NARINGENIN; QUERCETIN;

ARTICLE; BIOACCUMULATION; CELL STRAIN KB; CELL STRAIN KB C2; CONTROLLED STUDY; DRUG EFFECT; DRUG STRUCTURE; EFFUSION; FLOW CYTOMETRY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HYDROPHOBICITY; INTRACELLULAR TRANSPORT; MULTIDRUG RESISTANCE; PARTITION COEFFICIENT; PROTEIN FUNCTION; PROTEIN INTERACTION; STRUCTURE ACTIVITY RELATION;

EID: 28744436977     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.28.2274     Document Type: Article

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