Bioavailability and pharmacokinetics of caffeoylquinic acids and flavonoids after oral administration of Artichoke leaf extracts in humans

Phytomedicine

Volumn 12, Issue 1-2, 2005, Pages 28-38

  Wittemer, S M ^a   Ploch, M ^a   Windeck, T ^a   Muller S C ^b   Drewelow, B ^b   Derendorf, H ^c   Veit, M ^d  

^a Lichtwer Pharma AG   (Germany)

^b UNIVERSITY OF ROSTOCK   (Germany)

^c UNIVERSITY OF FLORIDA HEALTH   (United States)

^d LAT GmbH Dr Tittel   (Germany)

Author keywords

Artichoke; Bioavailability; Caffeoylquinic acids; Clinical trial; Luteolin 7 O glucoside

Indexed keywords

ARTICHOKE EXTRACT; CAFFEIC ACID; CAFFEIC ACID DERIVATIVE; DIHYDROCAFFEIC ACID; DIHYDROFERULIC ACID; DRUG METABOLITE; FERULIC ACID; FLAVONOID; GLUCOSIDE; GLUCURONIDE; ISOFERULIC ACID; LUTEOLIN; QUINIC ACID; SULFATE; UNCLASSIFIED DRUG;

ADULT; ARTICHOKE; ARTICLE; BLOOD ANALYSIS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; COULOMETRY; CROSSOVER PROCEDURE; DRUG ABSORPTION; DRUG ADMINISTRATION ROUTE; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG DISPOSITION; DRUG ELIMINATION; DRUG METABOLISM; DRUG URINE LEVEL; FEMALE; HEMOCONCENTRATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; HYDROGENATION; MALE; METABOLITE; METHYLATION; NORMAL HUMAN; PLANT LEAF; PLASMA; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TIME; URINALYSIS; VALIDATION PROCESS;

ADMINISTRATION, ORAL; ADULT; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; CROSS-OVER STUDIES; CYNARA SCOLYMUS; FEMALE; FLAVONOIDS; HUMANS; MALE; PHYTOTHERAPY; PLANT EXTRACTS; PLANT LEAVES; QUINIC ACID;

CYNARA SCOLYMUS;

EID: 12944324240     PISSN: 09447113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phymed.2003.11.002     Document Type: Article

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