-
1
-
-
19644378841
-
Flavonoid structure-activity studies identify 6-prenylchrysin and tectochrysin as potent and specific inhibitors of breast cancer resistance protein ABCG2
-
Ahmed-Belkacem A, Pozza A, Munoz-Martinez F, Bates SE, Castanys S, Gamarro F, Di Pietro A, and Perez-Victoria JM (2005) Flavonoid structure-activity studies identify 6-prenylchrysin and tectochrysin as potent and specific inhibitors of breast cancer resistance protein ABCG2. Cancer Res 65:4852-4860.
-
(2005)
Cancer Res
, vol.65
, pp. 4852-4860
-
-
Ahmed-Belkacem, A.1
Pozza, A.2
Munoz-Martinez, F.3
Bates, S.E.4
Castanys, S.5
Gamarro, F.6
Di Pietro, A.7
Perez-Victoria, J.M.8
-
2
-
-
0018894476
-
Absorption of sodium gamma-hydroxybutyrate and its prodrug gamma-butyrolactone: Relationship between in vitro transport and in vivo absorption
-
Arena C and Fung HL (1980) Absorption of sodium gamma-hydroxybutyrate and its prodrug gamma-butyrolactone: relationship between in vitro transport and in vivo absorption. J Pharm Sci 69:356-358.
-
(1980)
J Pharm Sci
, vol.69
, pp. 356-358
-
-
Arena, C.1
Fung, H.L.2
-
3
-
-
0018649222
-
Inhibition of lactate transport and glycolysis in Ehrlich ascites tumor cells by bioflavonoids
-
Belt JA, Thomas JA, Buchsbaum RN, and Racker E (1979) Inhibition of lactate transport and glycolysis in Ehrlich ascites tumor cells by bioflavonoids. Biochemistry 18:3506-3511.
-
(1979)
Biochemistry
, vol.18
, pp. 3506-3511
-
-
Belt, J.A.1
Thomas, J.A.2
Buchsbaum, R.N.3
Racker, E.4
-
4
-
-
4644337779
-
GHB (gamma-hydroxybutyrate) carrier-mediated transport across the blood-brain barrier
-
Bhattacharya I and Boje KM (2004) GHB (gamma-hydroxybutyrate) carrier-mediated transport across the blood-brain barrier. J Pharmacol Exp Ther 311:92-98.
-
(2004)
J Pharmacol Exp Ther
, vol.311
, pp. 92-98
-
-
Bhattacharya, I.1
Boje, K.M.2
-
5
-
-
0024457633
-
Monocarboxylate transporter in red blood cells: Kinetics and chemical modification
-
Deuticke B (1989) Monocarboxylate transporter in red blood cells: kinetics and chemical modification. Methods Enzymol 173:300-329.
-
(1989)
Methods Enzymol
, vol.173
, pp. 300-329
-
-
Deuticke, B.1
-
6
-
-
18244376403
-
Modulation by flavonoids of cell multidrug resistance mediated by P-glycoprotein and related ABC transporters
-
Di Pietro A, Conseil G, Perez-Victoria JM, Dayan G, Baubichon-Cortay H, Trompier D, Steinfels E, Jault JM, de Wet H, Maitrejean M, et al. (2002) Modulation by flavonoids of cell multidrug resistance mediated by P-glycoprotein and related ABC transporters. Cell Mol Life Sci 59:307-322.
-
(2002)
Cell Mol Life Sci
, vol.59
, pp. 307-322
-
-
Di Pietro, A.1
Conseil, G.2
Perez-Victoria, J.M.3
Dayan, G.4
Baubichon-Cortay, H.5
Trompier, D.6
Steinfels, E.7
Jault, J.M.8
de Wet, H.9
Maitrejean, M.10
-
7
-
-
0026794477
-
Pharmacokinetics of gamma-hydroxybutyric acid in alcohol dependent patients after single and repeated oral doses
-
Ferrara SD, Zotti S, Tedeschi L, Frison G, Castagna F, Gallimberti L, Gessa GL, and Palatini P (1992) Pharmacokinetics of gamma-hydroxybutyric acid in alcohol dependent patients after single and repeated oral doses. Br J Clin Pharmacol 34:231-235.
-
(1992)
Br J Clin Pharmacol
, vol.34
, pp. 231-235
-
-
Ferrara, S.D.1
Zotti, S.2
Tedeschi, L.3
Frison, G.4
Castagna, F.5
Gallimberti, L.6
Gessa, G.L.7
Palatini, P.8
-
8
-
-
33645100643
-
Effects of herbal extracts on the function of human organic anion-transporting polypeptide OATP-B
-
Fuchikami H, Satoh H, Tsujimoto M, Ohdo S, Ohtani H, and Sawada Y (2006) Effects of herbal extracts on the function of human organic anion-transporting polypeptide OATP-B. Drug Metab Dispos 34:577-582.
-
(2006)
Drug Metab Dispos
, vol.34
, pp. 577-582
-
-
Fuchikami, H.1
Satoh, H.2
Tsujimoto, M.3
Ohdo, S.4
Ohtani, H.5
Sawada, Y.6
-
9
-
-
2942615356
-
Liquid chromatographic-mass spectrometric determination of endogenous gamma-hydroxybutyrate concentrations in rat brain regions and plasma
-
Fung HL, Haas E, Raybon J, Xu J, and Fung SM (2004) Liquid chromatographic-mass spectrometric determination of endogenous gamma-hydroxybutyrate concentrations in rat brain regions and plasma. J Chromatogr B Analyt Technol Biomed Life Sci 807:287-291.
-
(2004)
J Chromatogr B Analyt Technol Biomed Life Sci
, vol.807
, pp. 287-291
-
-
Fung, H.L.1
Haas, E.2
Raybon, J.3
Xu, J.4
Fung, S.M.5
-
10
-
-
0028294023
-
Molecular characterization of a membrane transporter for lactate, pyruvate, and other monocarboxylates: Implications for the Cori cycle
-
Garcia CK, Goldstein JL, Pathak RK, Anderson RG, and Brown MS (1994) Molecular characterization of a membrane transporter for lactate, pyruvate, and other monocarboxylates: implications for the Cori cycle. Cell 76:865-873.
-
(1994)
Cell
, vol.76
, pp. 865-873
-
-
Garcia, C.K.1
Goldstein, J.L.2
Pathak, R.K.3
Anderson, R.G.4
Brown, M.S.5
-
11
-
-
0030837750
-
Expression of monocarboxylate transporter MCT1 by brain endothelium and glia in adult and suckling rats
-
Gerhart DZ, Enerson BE, Zhdankina OY, Leino RL, and Drewes LR (1997) Expression of monocarboxylate transporter MCT1 by brain endothelium and glia in adult and suckling rats. Am J Physiol 273:E207-E213.
-
(1997)
Am J Physiol
, vol.273
-
-
Gerhart, D.Z.1
Enerson, B.E.2
Zhdankina, O.Y.3
Leino, R.L.4
Drewes, L.R.5
-
12
-
-
0002832095
-
The isobolographic method applied to drug interactions
-
Moselli P, Garattini S, and Cohen S eds pp, Raven Press, New York
-
Gessner PK (1974) The isobolographic method applied to drug interactions, in Drug Interactions (Moselli P, Garattini S, and Cohen S eds) pp 349-362, Raven Press, New York.
-
(1974)
Drug Interactions
, pp. 349-362
-
-
Gessner, P.K.1
-
13
-
-
1242340302
-
The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond
-
Halestrap AP and Meredith D (2004) The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond. Pflueg Arch Eur J Physiol 447:619-628.
-
(2004)
Pflueg Arch Eur J Physiol
, vol.447
, pp. 619-628
-
-
Halestrap, A.P.1
Meredith, D.2
-
14
-
-
0033569442
-
The proton-linked monocarboxylate transporter (MCT) family: Structure, function and regulation
-
Halestrap AP and Price NT (1999) The proton-linked monocarboxylate transporter (MCT) family: structure, function and regulation. Biochem J 343 (Pt 2):281-299.
-
(1999)
Biochem J
, vol.343
, Issue.PART 2
, pp. 281-299
-
-
Halestrap, A.P.1
Price, N.T.2
-
15
-
-
0034254638
-
CD147 is tightly associated with lactate transporters MCT1 and MCT4 and facilitates their cell surface expression
-
Kirk P, Wilson MC, Heddle C, Brown MH, Barclay AN, and Halestrap AP (2000) CD147 is tightly associated with lactate transporters MCT1 and MCT4 and facilitates their cell surface expression. EMBO (Eur Mol Biol Organ) J 19:3896-3904.
-
(2000)
EMBO (Eur Mol Biol Organ) J
, vol.19
, pp. 3896-3904
-
-
Kirk, P.1
Wilson, M.C.2
Heddle, C.3
Brown, M.H.4
Barclay, A.N.5
Halestrap, A.P.6
-
16
-
-
13244258342
-
Transepithelial transport of microbial metabolites of quercetin in intestinal Caco-2 cell monolayers
-
Konishi Y (2005) Transepithelial transport of microbial metabolites of quercetin in intestinal Caco-2 cell monolayers. J Agric Food Chem 53:601-607.
-
(2005)
J Agric Food Chem
, vol.53
, pp. 601-607
-
-
Konishi, Y.1
-
17
-
-
0018372970
-
Dose-dependent pharmacokinetics and hypnotic effects of sodium gamma-hydroxybutyrate in the rat
-
Lettieri JT and Fung HL (1979) Dose-dependent pharmacokinetics and hypnotic effects of sodium gamma-hydroxybutyrate in the rat. J Pharmacol Exp Ther 208:7-11.
-
(1979)
J Pharmacol Exp Ther
, vol.208
, pp. 7-11
-
-
Lettieri, J.T.1
Fung, H.L.2
-
18
-
-
0032582702
-
Human monocarboxylate transporter 2 (MCT2) is a high affinity pyruvate transporter
-
Lin RY, Vera JC, Chaganti RS, and Golde DW (1998) Human monocarboxylate transporter 2 (MCT2) is a high affinity pyruvate transporter. J Biol Chem 273:28959-28965.
-
(1998)
J Biol Chem
, vol.273
, pp. 28959-28965
-
-
Lin, R.Y.1
Vera, J.C.2
Chaganti, R.S.3
Golde, D.W.4
-
19
-
-
34250958584
-
Effect of combinations: Mathematical basis of the problem
-
Loewe S and Muischnek H (1926) Effect of combinations: mathematical basis of the problem. Arch Exp Pathol Pharmakol 114:313-326.
-
(1926)
Arch Exp Pathol Pharmakol
, vol.114
, pp. 313-326
-
-
Loewe, S.1
Muischnek, H.2
-
20
-
-
0018888515
-
Sequential alterations of cerebral carbohydrate metabolism associated with gamma-hydroxybutyrate
-
Macmillan V (1980) Sequential alterations of cerebral carbohydrate metabolism associated with gamma-hydroxybutyrate. Brain Res 183:123-134.
-
(1980)
Brain Res
, vol.183
, pp. 123-134
-
-
Macmillan, V.1
-
21
-
-
19444362090
-
Renal clearance of gamma-hydroxybutyric acid in rats: Increasing renal elimination as a detoxification strategy
-
Morris ME, Hu K, and Wang Q (2005) Renal clearance of gamma-hydroxybutyric acid in rats: increasing renal elimination as a detoxification strategy. J Pharmacol Exp Ther 313:1194-1202.
-
(2005)
J Pharmacol Exp Ther
, vol.313
, pp. 1194-1202
-
-
Morris, M.E.1
Hu, K.2
Wang, Q.3
-
22
-
-
33644914487
-
Flavonoid-drug interactions: Effects of flavonoids on ABC transporters
-
Morris ME and Zhang S (2006) Flavonoid-drug interactions: effects of flavonoids on ABC transporters. Life Sci 78:2116-2130.
-
(2006)
Life Sci
, vol.78
, pp. 2116-2130
-
-
Morris, M.E.1
Zhang, S.2
-
23
-
-
0034836506
-
Flavonoids: A review of probable mechanisms of action and potential applications
-
Nijveldt RJ, van Nood E, van Hoorn DE, Boelens PG, van Norren K, and van Leeuwen PA (2001) Flavonoids: a review of probable mechanisms of action and potential applications. Am J Clin Nutr 74:418-425.
-
(2001)
Am J Clin Nutr
, vol.74
, pp. 418-425
-
-
Nijveldt, R.J.1
van Nood, E.2
van Hoorn, D.E.3
Boelens, P.G.4
van Norren, K.5
van Leeuwen, P.A.6
-
24
-
-
0027364308
-
Dose-dependent absorption and elimination of gamma-hydroxybutyric acid in healthy volunteers
-
Palatini P, Tedeschi L, Frison G, Padrini R, Zordan R, Orlando R, Gallimberti L, Gessa GL, and Ferrara SD (1993) Dose-dependent absorption and elimination of gamma-hydroxybutyric acid in healthy volunteers. Eur J Clin Pharmacol 45:353-356.
-
(1993)
Eur J Clin Pharmacol
, vol.45
, pp. 353-356
-
-
Palatini, P.1
Tedeschi, L.2
Frison, G.3
Padrini, R.4
Zordan, R.5
Orlando, R.6
Gallimberti, L.7
Gessa, G.L.8
Ferrara, S.D.9
-
25
-
-
12244262261
-
Cellular and subcellular distribution of monocarboxylate transporters in cultured brain cells and in the adult brain
-
Pellerin L, Bergersen LH, Halestrap AP, and Pierre K (2005) Cellular and subcellular distribution of monocarboxylate transporters in cultured brain cells and in the adult brain. J Neurosci Res 79:55-64.
-
(2005)
J Neurosci Res
, vol.79
, pp. 55-64
-
-
Pellerin, L.1
Bergersen, L.H.2
Halestrap, A.P.3
Pierre, K.4
-
26
-
-
0032521113
-
The characterization of butyrate transport across pig and human colonic luminal membrane
-
Ritzhaupt A, Ellis A, Hosie KB, and Shirazi-Beechey SP (1998a) The characterization of butyrate transport across pig and human colonic luminal membrane. J Physiol 507 (Pt 3):819-830.
-
(1998)
J Physiol
, vol.507
, Issue.PART 3
, pp. 819-830
-
-
Ritzhaupt, A.1
Ellis, A.2
Hosie, K.B.3
Shirazi-Beechey, S.P.4
-
27
-
-
0032535722
-
Identification and characterization of a monocarboxylate transporter (MCT1) in pig and human colon: Its potential to transport L-lactate as well as butyrate
-
Ritzhaupt A, Wood IS, Ellis A, Hosie KB, and Shirazi-Beechey SP (1998b) Identification and characterization of a monocarboxylate transporter (MCT1) in pig and human colon: its potential to transport L-lactate as well as butyrate. J Physiol 513 (Pt 3):719-732.
-
(1998)
J Physiol
, vol.513
, Issue.PART 3
, pp. 719-732
-
-
Ritzhaupt, A.1
Wood, I.S.2
Ellis, A.3
Hosie, K.B.4
Shirazi-Beechey, S.P.5
-
28
-
-
0031738302
-
Intestinal absorption of luteolin and luteolin 7-O-beta-glucoside in rats and humans
-
Shimoi K, Okada H, Furugori M, Goda T, Takase S, Suzuki M, Hara Y, Yamamoto H, and Kinae N (1998) Intestinal absorption of luteolin and luteolin 7-O-beta-glucoside in rats and humans. FEBS Lett 438:220-224.
-
(1998)
FEBS Lett
, vol.438
, pp. 220-224
-
-
Shimoi, K.1
Okada, H.2
Furugori, M.3
Goda, T.4
Takase, S.5
Suzuki, M.6
Hara, Y.7
Yamamoto, H.8
Kinae, N.9
-
29
-
-
0018367233
-
Plasma and central nervous system kinetics of gamma-hydroxybutyrate
-
Shumate JS and Snead OC 3rd (1979) Plasma and central nervous system kinetics of gamma-hydroxybutyrate. Res Commun Chem Pathol Pharmacol 25:241-256.
-
(1979)
Res Commun Chem Pathol Pharmacol
, vol.25
, pp. 241-256
-
-
Shumate, J.S.1
Snead III, O.C.2
-
30
-
-
0037678912
-
Gamma-hydroxybutyrate serum levels and clinical syndrome after severe overdose
-
Sporer KA, Chin RL, Dyer JE, and Lamb R (2003) Gamma-hydroxybutyrate serum levels and clinical syndrome after severe overdose. Ann Emerg Med 42:3-8.
-
(2003)
Ann Emerg Med
, vol.42
, pp. 3-8
-
-
Sporer, K.A.1
Chin, R.L.2
Dyer, J.E.3
Lamb, R.4
-
31
-
-
0142241274
-
Cellular uptake and efflux of the tea flavonoid (-)epicatechin-3-gallate in the human intestinal cell line Caco-2
-
Vaidyanathan JB and Walle T (2003) Cellular uptake and efflux of the tea flavonoid (-)epicatechin-3-gallate in the human intestinal cell line Caco-2. J Pharmacol Exp Ther 307:745-752.
-
(2003)
J Pharmacol Exp Ther
, vol.307
, pp. 745-752
-
-
Vaidyanathan, J.B.1
Walle, T.2
-
32
-
-
33745955759
-
Transport of gamma-hydroxybutyrate in rat kidney membrane vesicles - role of monocarboxylate transporters
-
Wang Q, Darling IM, and Morris ME (2006) Transport of gamma-hydroxybutyrate in rat kidney membrane vesicles - role of monocarboxylate transporters. J Pharmacol Exp Ther 318:751-761.
-
(2006)
J Pharmacol Exp Ther
, vol.318
, pp. 751-761
-
-
Wang, Q.1
Darling, I.M.2
Morris, M.E.3
-
33
-
-
33846520981
-
Monocarboxylate transporter-1 (MCT1) mediates γ-hydroxybutyrate transport In human kidney HK2 cells
-
Wang Q, Lu Y, Yuan M, Repasky E, and Morris M (2005a) Monocarboxylate transporter-1 (MCT1) mediates γ-hydroxybutyrate transport In human kidney HK2 cells. AAPS J 7:R6290.
-
(2005)
AAPS J
, vol.7
-
-
Wang, Q.1
Lu, Y.2
Yuan, M.3
Repasky, E.4
Morris, M.5
-
34
-
-
27544453625
-
Flavonoids as a novel class of human organic anion-transporting polypeptide OATP1B1 (OATP-C) modulators
-
Wang X, Wolkoff AW, and Morris ME (2005b) Flavonoids as a novel class of human organic anion-transporting polypeptide OATP1B1 (OATP-C) modulators. Drug Metab Dispos 33:1666-1672.
-
(2005)
Drug Metab Dispos
, vol.33
, pp. 1666-1672
-
-
Wang, X.1
Wolkoff, A.W.2
Morris, M.E.3
-
35
-
-
11144258924
-
Activation of mitochondrial lactate uptake by flavone induces apoptosis in human colon cancer cells
-
Wenzel U, Schoberl K, Lohner K, and Daniel H (2005) Activation of mitochondrial lactate uptake by flavone induces apoptosis in human colon cancer cells. J Cell Physiol 202:379-390.
-
(2005)
J Cell Physiol
, vol.202
, pp. 379-390
-
-
Wenzel, U.1
Schoberl, K.2
Lohner, K.3
Daniel, H.4
-
36
-
-
22844442936
-
Basigin (CD147) is the target for organomercurial inhibition of monocarboxylate isoforms 1 and 4: The ancillary protein for the insensitive MCT2 is embigin (gp70)
-
Wilson M, Meredith D, Manning FJ, Manoharan C, Davies A, and Halestrap A (2005) Basigin (CD147) is the target for organomercurial inhibition of monocarboxylate isoforms 1 and 4: the ancillary protein for the insensitive MCT2 is embigin (gp70). J Biol Chem 280:29213-29221.
-
(2005)
J Biol Chem
, vol.280
, pp. 29213-29221
-
-
Wilson, M.1
Meredith, D.2
Manning, F.J.3
Manoharan, C.4
Davies, A.5
Halestrap, A.6
-
37
-
-
0037371275
-
Effects of the flavonoids biochanin A, morin, phloretin, and silymarin on P-glycoprotein-mediated transport
-
Zhang S and Morris ME (2003) Effects of the flavonoids biochanin A, morin, phloretin, and silymarin on P-glycoprotein-mediated transport. J Pharmacol Exp Ther 304:1258-1267.
-
(2003)
J Pharmacol Exp Ther
, vol.304
, pp. 1258-1267
-
-
Zhang, S.1
Morris, M.E.2
-
38
-
-
0035843255
-
Adverse events, including death, associated with the use of 1,4-butanediol
-
Zvosec DL, Smith SW, McCutcheon JR, Spillane J, Hall BJ, and Peacock EA (2001) Adverse events, including death, associated with the use of 1,4-butanediol. N Engl J Med 344:87-94.
-
(2001)
N Engl J Med
, vol.344
, pp. 87-94
-
-
Zvosec, D.L.1
Smith, S.W.2
McCutcheon, J.R.3
Spillane, J.4
Hall, B.J.5
Peacock, E.A.6
|