Effect of bioflavonoids on vincristine transport across blood-brain barrier

European Journal of Pharmacology

Volumn 395, Issue 3, 2000, Pages 193-201

  Mitsunaga, Yoshiharu ^a   Takanaga, Hitomi ^a   Matsuo, Hirotami ^a   Naito, Mikihiko ^b   Tsuruo, Takashi ^b   Ohtani, Hisakazu ^a   Sawada, Yasufumi ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

Bioflavonoid; Blood brain barrier; P Glycoprotein; Protein kinase C; Vincristine

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; 2 [1 (3 AMIDINOTHIOPROPYL) 1H INDOL 3 YL] 3 (1 METHYL 1H INDOL 3 YL)MALEIMIDE; 3 METHYLGLUCOSE; AURANTIIN; BIOFLAVONOID; CHRYSIN; FISETIN; HESPERETIN; HESPERIDIN; K 252A; NARINGENIN; PHENYLALANINE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C; QUERCETIN; RUTOSIDE; STAUROSPORINE; VERAPAMIL; VINCRISTINE;

ANIMAL CELL; ARTICLE; BLOOD BRAIN BARRIER; BRAIN CAPILLARY; CAPILLARY ENDOTHELIUM; CELL MEMBRANE TRANSPORT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG UPTAKE; ENZYME ACTIVATION; ENZYME INHIBITION; FRUIT JUICE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSPORT KINETICS;

3-O-METHYLGLUCOSE; ANIMALS; BIOLOGICAL TRANSPORT; BLOOD-BRAIN BARRIER; BRAIN; CARBON RADIOISOTOPES; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; FLAVONOIDS; KAEMPFEROLS; MICE; P-GLYCOPROTEIN; PHENYLALANINE; PHOSPHORUS RADIOISOTOPES; PROTEIN KINASE C; QUERCETIN; TETRADECANOYLPHORBOL ACETATE; TRITIUM; VINCRISTINE;

EID: 0034600237     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(00)00180-1     Document Type: Article

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