Accumulation of orally administered quercetin in brain tissue and its antioxidative effects in rats

Free Radical Biology and Medicine

Volumn 51, Issue 7, 2011, Pages 1329-1336

  Ishisaka, Akari ^a   Ichikawa, Satomi ^a,e   Sakakibara, Hiroyuki ^a,f   Piskula, Mariusz K ^b   Nakamura, Toshiyuki ^a,c   Kato, Yoji ^c   Ito, Mikiko ^a,c   Miyamoto, Ken Ichi ^a   Tsuji, Akira ^d   Kawai, Yoshichika ^a   Terao, Junji ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b INSTITUTE OF ANIMAL REPRODUCTION AND FOOD RESEARCH   (Poland)

^c UNIVERSITY OF HYOGO   (Japan)

^d KANAZAWA UNIVERSITY   (Japan)

^e MEIJI SEIKA KAISHA LTD   (Japan)

^f UNIVERSITY OF SHIZUOKA   (Japan)

Author keywords

Blood brain barrier; Brain; Chromatography; Free radicals; Oxidative stress; Quercetin

Indexed keywords

BETA GLUCURONIDASE; HEMOGLOBIN; QUERCETIN; SULFATASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; BLOOD BRAIN BARRIER; BRAIN TISSUE; CONTROLLED STUDY; CORPUS STRIATUM; DRUG ACCUMULATION; DRUG RELEASE; DRUG STRUCTURE; ELECTROCHEMICAL DETECTION; FORCED SWIMMING TEST; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIPPOCAMPUS; HOMOGENATE; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ADMINISTRATION, ORAL; ANIMALS; ANTIOXIDANTS; BLOOD-BRAIN BARRIER; BRAIN; CELLS, CULTURED; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ELECTROCHEMICAL TECHNIQUES; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; GLUCURONIDASE; HUMANS; MALE; METHYLATION; NEURODEGENERATIVE DISEASES; OXIDATIVE STRESS; QUERCETIN; RATS; RATS, WISTAR; SULFOTRANSFERASES; TANDEM MASS SPECTROMETRY; TISSUE EXTRACTS;

RATTUS;

EID: 80052269348     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2011.06.017     Document Type: Article

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