Notch inhibitors for cancer treatment

Pharmacology and Therapeutics

Volumn 139, Issue 2, 2013, Pages 95-110

  Espinoza, Ingrid ^a   Miele, Lucio ^a  

^a UNIVERSITY OF MISSISSIPPI   (United States)

Author keywords

Cancer; Cancer stem cells; Notch inhibitors; Notch signaling

Indexed keywords

A 5622A; ANTINEOPLASTIC AGENT; AVAGACESTAT; CURCUMIN; DEMCIZUMAB; GENISTEIN; HELIX LOOP HELIX PROTEIN; MONOCLONAL ANTIBODY NOTCH 1; MONOCLONAL ANTIBODY NOTCH 2; MONOCLONAL ANTIBODY NOTCH 3; MRK 003; MRK 0752; N (6,7 DIHYDRO 6 OXO 5H DIBENZ[B,D]AZEPIN 7 YL) 2,2 DIMETHYL N' (2,2,3,3,3 PENTAFLUOROPROPYL)PROPANEDIAMIDE; NOTCH INHIBITOR; NOTCH RECEPTOR; NOTCH1 RECEPTOR; NOTCH2 RECEPTOR; NOTCH3 RECEPTOR; NOTCH4 RECEPTOR; OMP 59R5; PF 3084014; QUERCETIN; RESVERATROL; SULFORAPHANE; UNCLASSIFIED DRUG;

ACUTE LYMPHOBLASTIC LEUKEMIA; AMINO TERMINAL SEQUENCE; ANAPLASTIC CARCINOMA; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; BINDING SITE; BRAIN TUMOR; BREAST CANCER; CANCER STEM CELL; CANCER THERAPY; CARBOXY TERMINAL SEQUENCE; CARCINOID; CELL DIFFERENTIATION; CELL PROLIFERATION; CHROMOSOME REARRANGEMENT; COLON CANCER; COLORECTAL CANCER; DNA REPAIR; DNA REPLICATION; DROSOPHILA; DRUG HALF LIFE; DRUG SAFETY; DRUG TOLERABILITY; GAIN OF FUNCTION MUTATION; HISTONE ACETYLATION; HUMAN; HYDROPHOBICITY; HYDROXYLATION; LIVER METABOLISM; LONG TERMINAL REPEAT; LUNG SMALL CELL CANCER; LYMPHATIC LEUKEMIA; MELANOMA; NONHUMAN; OVERALL SURVIVAL; PANCREAS CANCER; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN BINDING; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN GLYCOSYLATION; PROTEIN METABOLISM; PROTEIN PHOSPHORYLATION; REVIEW; SOLID TUMOR; T CELL LEUKEMIA; THYROID CANCER; UBIQUITINATION;

ANIMALS; ANTINEOPLASTIC AGENTS; HUMANS; NEOPLASMS; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION;

EID: 84879422834     PISSN: 01637258     EISSN: 1879016X     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2013.02.003     Document Type: Review

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