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Volumn 8, Issue 8, 2007, Pages 959-969

Notch signaling - Constantly on the move

Author keywords

Cellular signaling; DSL ligands; Endocytosis; Membrane trafficking; Notch; Recycling; Trans endocytosis

Indexed keywords

AUXILIN; CBL PROTEIN; EPSIN; NOTCH RECEPTOR; RAB PROTEIN; RAB11 PROTEIN; RAB5 PROTEIN; RAL PROTEIN; RALA PROTEIN; UBIQUITIN PROTEIN LIGASE E3; UBIQUITIN PROTEIN LIGASE NEDD4; UNCLASSIFIED DRUG;

EID: 34447509872     PISSN: 13989219     EISSN: 16000854     Source Type: Journal    
DOI: 10.1111/j.1600-0854.2007.00592.x     Document Type: Review
Times cited : (116)

References (94)
  • 1
    • 0033617522 scopus 로고    scopus 로고
    • Notch signaling: Cell fate control and signal integration in development
    • Artavanis-Tsakonas S, Rand MD, Lake RJ. Notch signaling: Cell fate control and signal integration in development. Science 1999; 284: 770-776.
    • (1999) Science , vol.284 , pp. 770-776
    • Artavanis-Tsakonas, S.1    Rand, M.D.2    Lake, R.J.3
  • 2
    • 33747623018 scopus 로고    scopus 로고
    • Notch signalling: A simple pathway becomes complex
    • Bray SJ. Notch signalling: A simple pathway becomes complex. Nat Rev Mol Cell Biol 2006; 7: 678-689.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 678-689
    • Bray, S.J.1
  • 5
    • 33745747388 scopus 로고    scopus 로고
    • Endosome dynamics during development
    • Emery G, Knoblich JA. Endosome dynamics during development. Curr Opin Cell Biol 2006; 18: 407-415.
    • (2006) Curr Opin Cell Biol , vol.18 , pp. 407-415
    • Emery, G.1    Knoblich, J.A.2
  • 6
    • 33751173885 scopus 로고    scopus 로고
    • Endocytosis, endosome trafficking, and the regulation of Drosophila development
    • Fischer JA, Eun SH, Doolan BT. Endocytosis, endosome trafficking, and the regulation of Drosophila development. Annu Rev Cell Dev Biol 2006; 22: 181-206.
    • (2006) Annu Rev Cell Dev Biol , vol.22 , pp. 181-206
    • Fischer, J.A.1    Eun, S.H.2    Doolan, B.T.3
  • 7
    • 33644857880 scopus 로고    scopus 로고
    • Regulation of notch signalling by endocytosis and endosomal sorting
    • Le Borgne R. Regulation of notch signalling by endocytosis and endosomal sorting. Curr Opin Cell Biol 2006; 18: 213-222.
    • (2006) Curr Opin Cell Biol , vol.18 , pp. 213-222
    • Le Borgne, R.1
  • 8
    • 18844414504 scopus 로고    scopus 로고
    • The roles of receptor and ligand endocytosis in regulating notch signaling
    • Le Borgne R, Bardin A, Schweisguth F. The roles of receptor and ligand endocytosis in regulating notch signaling. Development 2005; 132: 1751-1762.
    • (2005) Development , vol.132 , pp. 1751-1762
    • Le Borgne, R.1    Bardin, A.2    Schweisguth, F.3
  • 9
    • 27144452592 scopus 로고    scopus 로고
    • Endocytic regulation of notch activation and down-regulation (review)
    • Wilkin MB, Baron M. Endocytic regulation of notch activation and down-regulation (review). Mol Membr Biol 2005; 22: 279-289.
    • (2005) Mol Membr Biol , vol.22 , pp. 279-289
    • Wilkin, M.B.1    Baron, M.2
  • 10
    • 0031573944 scopus 로고    scopus 로고
    • Requirement for dynamin during notch signaling in Drosophila neurogenesis
    • Seugnet L, Simpson P, Haenlin M. Requirement for dynamin during notch signaling in Drosophila neurogenesis. Dev Biol 1997; 192: 585-598.
    • (1997) Dev Biol , vol.192 , pp. 585-598
    • Seugnet, L.1    Simpson, P.2    Haenlin, M.3
  • 11
    • 0032705926 scopus 로고    scopus 로고
    • Ligand-receptor interactions and trans-endocytosis of delta, serrate and notch: Members of the notch signalling pathway in Drosophila
    • Klueg KM, Muskavitch MA. Ligand-receptor interactions and trans-endocytosis of delta, serrate and notch: Members of the notch signalling pathway in Drosophila. J Cell Sci 1999; 112: 3289-3297.
    • (1999) J Cell Sci , vol.112 , pp. 3289-3297
    • Klueg, K.M.1    Muskavitch, M.A.2
  • 12
    • 0031846155 scopus 로고    scopus 로고
    • Complex proteolytic processing acts on delta, a transmembrane ligand for notch, during Drosophila development
    • Klueg KM, Parody TR, Muskavitch MA. Complex proteolytic processing acts on delta, a transmembrane ligand for notch, during Drosophila development. Mol Biol Cell 1998; 9: 1709-1723.
    • (1998) Mol Biol Cell , vol.9 , pp. 1709-1723
    • Klueg, K.M.1    Parody, T.R.2    Muskavitch, M.A.3
  • 13
    • 0027416250 scopus 로고
    • Implications of dynamic patterns of delta and notch expression for cellular interactions during Drosophila development
    • Kooh PJ, Fehon RG, Muskavitch MA. Implications of dynamic patterns of delta and notch expression for cellular interactions during Drosophila development. Development 1993; 117: 493-507.
    • (1993) Development , vol.117 , pp. 493-507
    • Kooh, P.J.1    Fehon, R.G.2    Muskavitch, M.A.3
  • 14
    • 0034051852 scopus 로고    scopus 로고
    • Ligand endocytosis drives receptor dissociation and activation in the notch pathway
    • Parks AL, Klueg KM, Stout JR, Muskavitch MA. Ligand endocytosis drives receptor dissociation and activation in the notch pathway. Development 2000; 127: 1373-1385.
    • (2000) Development , vol.127 , pp. 1373-1385
    • Parks, A.L.1    Klueg, K.M.2    Stout, J.R.3    Muskavitch, M.A.4
  • 16
    • 0038686503 scopus 로고    scopus 로고
    • Unequal segregation of Neuralized biases notch activation during asymmetric cell division
    • Le Borgne R, Schweisguth F. Unequal segregation of Neuralized biases notch activation during asymmetric cell division. Dev Cell 2003; 5: 139-148.
    • (2003) Dev Cell , vol.5 , pp. 139-148
    • Le Borgne, R.1    Schweisguth, F.2
  • 17
    • 1542267408 scopus 로고    scopus 로고
    • Three modules of zebrafish mind bomb work cooperatively to promote delta ubiquitination and endocytosis
    • Chen W, Casey Corliss D. Three modules of zebrafish mind bomb work cooperatively to promote delta ubiquitination and endocytosis. Dev Biol 2004; 267: 361-373.
    • (2004) Dev Biol , vol.267 , pp. 361-373
    • Chen, W.1    Casey Corliss, D.2
  • 18
    • 0035650895 scopus 로고    scopus 로고
    • Xenopus neuralized is a ubiquitin ligase that interacts with XDelta1 and regulates notch signaling
    • Deblandre GA, Lai EC, Kintner C. Xenopus neuralized is a ubiquitin ligase that interacts with XDelta1 and regulates notch signaling. Dev Cell 2001; 1: 795-806.
    • (2001) Dev Cell , vol.1 , pp. 795-806
    • Deblandre, G.A.1    Lai, E.C.2    Kintner, C.3
  • 20
    • 0035651380 scopus 로고    scopus 로고
    • Drosophila neuralized is a ubiquitin ligase that promotes the internalization and degradation of delta
    • Lai EC, Deblandre GA, Kintner C, Rubin GM. Drosophila neuralized is a ubiquitin ligase that promotes the internalization and degradation of delta. Dev Cell 2001; 1: 783-794.
    • (2001) Dev Cell , vol.1 , pp. 783-794
    • Lai, E.C.1    Deblandre, G.A.2    Kintner, C.3    Rubin, G.M.4
  • 21
    • 0035653308 scopus 로고    scopus 로고
    • Delidakis C. neuralized Encodes a peripheral membrane protein involved in delta signaling and endocytosis
    • Pavlopoulos E, Pitsouli C, Klueg KM, Muskavitch MA, Moschonas NK, Delidakis C. neuralized Encodes a peripheral membrane protein involved in delta signaling and endocytosis. Dev Cell 2001; 1: 807-816.
    • (2001) Dev Cell , vol.1 , pp. 807-816
    • Pavlopoulos, E.1    Pitsouli, C.2    Klueg, K.M.3    Muskavitch, M.A.4    Moschonas, N.K.5
  • 22
    • 0035975961 scopus 로고    scopus 로고
    • Neuralized functions as an E3 ubiquitin ligase during Drosophila development
    • Yeh E, Dermer M, Commisso C, Zhou L, McGlade CJ, Boulianne GL. Neuralized functions as an E3 ubiquitin ligase during Drosophila development. Curr Biol 2001; 11: 1675-1679.
    • (2001) Curr Biol , vol.11 , pp. 1675-1679
    • Yeh, E.1    Dermer, M.2    Commisso, C.3    Zhou, L.4    McGlade, C.J.5    Boulianne, G.L.6
  • 23
    • 33750202549 scopus 로고    scopus 로고
    • Role of conserved intracellular motifs in serrate signalling, cis-inhibition and endocytosis
    • Glittenberg M, Pitsouli C, Garvey C, Delidakis C, Bray S. Role of conserved intracellular motifs in serrate signalling, cis-inhibition and endocytosis. EMBO J 2006; 25: 4697-4706.
    • (2006) EMBO J , vol.25 , pp. 4697-4706
    • Glittenberg, M.1    Pitsouli, C.2    Garvey, C.3    Delidakis, C.4    Bray, S.5
  • 24
    • 9544221645 scopus 로고    scopus 로고
    • Fat facets and liquid facets promote delta endocytosis and delta signaling in the signaling cells
    • Overstreet E, Fitch E, Fischer JA. Fat facets and liquid facets promote delta endocytosis and delta signaling in the signaling cells. Development 2004; 131: 5355-5366.
    • (2004) Development , vol.131 , pp. 5355-5366
    • Overstreet, E.1    Fitch, E.2    Fischer, J.A.3
  • 25
    • 9444297354 scopus 로고    scopus 로고
    • Drosophila epsin mediates a select endocytic pathway that DSL ligands must enter to activate notch
    • Wang W, Struhl G. Drosophila epsin mediates a select endocytic pathway that DSL ligands must enter to activate notch. Development 2004; 131: 5367-5380.
    • (2004) Development , vol.131 , pp. 5367-5380
    • Wang, W.1    Struhl, G.2
  • 26
    • 21644462494 scopus 로고    scopus 로고
    • Distinct roles for mind bomb, neuralized and epsin in mediating DSL endocytosis and signaling in Drosophila
    • Wang W, Struhl G. Distinct roles for mind bomb, neuralized and epsin in mediating DSL endocytosis and signaling in Drosophila. Development 2005; 132: 2883-2894.
    • (2005) Development , vol.132 , pp. 2883-2894
    • Wang, W.1    Struhl, G.2
  • 28
    • 33646425317 scopus 로고    scopus 로고
    • Drosophila melanogaster auxilin regulates the internalization of delta to control activity of the notch signaling pathway
    • Hagedorn EJ, Bayraktar JL, Kandachar VR, Bai T, Englert DM, Chang HC. Drosophila melanogaster auxilin regulates the internalization of delta to control activity of the notch signaling pathway. J Cell Biol 2006; 173: 443-452.
    • (2006) J Cell Biol , vol.173 , pp. 443-452
    • Hagedorn, E.J.1    Bayraktar, J.L.2    Kandachar, V.R.3    Bai, T.4    Englert, D.M.5    Chang, H.C.6
  • 29
    • 33846968807 scopus 로고    scopus 로고
    • DSL ligand endocytosis physically dissociates notch1 heterodimers before activating proteolysis can occur
    • Nichols JT, Miyamoto A, Olsen SL, D'Souza B, Yao C, Weinmaster G. DSL ligand endocytosis physically dissociates notch1 heterodimers before activating proteolysis can occur. J Cell Biol 2007; 176: 445-458.
    • (2007) J Cell Biol , vol.176 , pp. 445-458
    • Nichols, J.T.1    Miyamoto, A.2    Olsen, S.L.3    D'Souza, B.4    Yao, C.5    Weinmaster, G.6
  • 30
    • 0038056104 scopus 로고    scopus 로고
    • Either part of a Drosophila epsin protein, divided after the ENTH domain, functions in endocytosis of delta in the developing eye
    • Overstreet E, Chen X, Wendland B, Fischer JA. Either part of a Drosophila epsin protein, divided after the ENTH domain, functions in endocytosis of delta in the developing eye. Curr Biol 2003; 13: 854-860.
    • (2003) Curr Biol , vol.13 , pp. 854-860
    • Overstreet, E.1    Chen, X.2    Wendland, B.3    Fischer, J.A.4
  • 31
    • 33947311208 scopus 로고    scopus 로고
    • Decoding ubiquitin sorting signals for clathrin-dependent endocytosis by CLASPs
    • Traub LM, Lukacs GL. Decoding ubiquitin sorting signals for clathrin-dependent endocytosis by CLASPs. J Cell Sci 2007; 120: 543-553.
    • (2007) J Cell Sci , vol.120 , pp. 543-553
    • Traub, L.M.1    Lukacs, G.L.2
  • 32
    • 6344263789 scopus 로고    scopus 로고
    • Cargo- and compartment-selective endocytic scaffold proteins
    • Szymkiewicz I, Shupliakov O, Dikic I. Cargo- and compartment-selective endocytic scaffold proteins. Biochem J 2004; 383: 1-11.
    • (2004) Biochem J , vol.383 , pp. 1-11
    • Szymkiewicz, I.1    Shupliakov, O.2    Dikic, I.3
  • 33
    • 34047222507 scopus 로고    scopus 로고
    • Selective blocking of clathrin-mediated endocytosis by RNA interference: Epsin as target protein
    • Vanden Broeck D, De Wolf MJ. Selective blocking of clathrin-mediated endocytosis by RNA interference: Epsin as target protein. Biotechniques 2006; 41: 475-484.
    • (2006) Biotechniques , vol.41 , pp. 475-484
    • Vanden Broeck, D.1    De Wolf, M.J.2
  • 34
    • 24144503375 scopus 로고    scopus 로고
    • Asymmetric Rab 11 endosomes regulate delta recycling and specify cell fate in the Drosophila nervous system
    • Emery G, Hutterer A, Berdnik D, Mayer B, Wirtz-Peitz F, Gaitan MG, Knoblich JA. Asymmetric Rab 11 endosomes regulate delta recycling and specify cell fate in the Drosophila nervous system. Cell 2005; 122: 763-773.
    • (2005) Cell , vol.122 , pp. 763-773
    • Emery, G.1    Hutterer, A.2    Berdnik, D.3    Mayer, B.4    Wirtz-Peitz, F.5    Gaitan, M.G.6    Knoblich, J.A.7
  • 35
    • 24144477936 scopus 로고    scopus 로고
    • Drosophila exocyst components Sec5, Sec6, and Sec15 regulate DE-Cadherin trafficking from recycling endosomes to the plasma membrane
    • Langevin J, Morgan MJ, Sibarita JB, Aresta S, Murthy M, Schwarz T, Camonis J, Bellaiche Y. Drosophila exocyst components Sec5, Sec6, and Sec15 regulate DE-Cadherin trafficking from recycling endosomes to the plasma membrane. Dev Cell 2005; 9: 355-376.
    • (2005) Dev Cell , vol.9 , pp. 355-376
    • Langevin, J.1    Morgan, M.J.2    Sibarita, J.B.3    Aresta, S.4    Murthy, M.5    Schwarz, T.6    Camonis, J.7    Bellaiche, Y.8
  • 36
    • 24144499951 scopus 로고    scopus 로고
    • Sec15, a component of the exocyst, promotes notch signaling during the asymmetric division of Drosophila sensory organ precursors
    • Jafar-Nejad H, Andrews HK, Acar M, Bayat V, Wirtz-Peitz F, Mehta SQ, Knoblich JA, Bellen HJ. Sec15, a component of the exocyst, promotes notch signaling during the asymmetric division of Drosophila sensory organ precursors. Dev Cell 2005; 9: 351-363.
    • (2005) Dev Cell , vol.9 , pp. 351-363
    • Jafar-Nejad, H.1    Andrews, H.K.2    Acar, M.3    Bayat, V.4    Wirtz-Peitz, F.5    Mehta, S.Q.6    Knoblich, J.A.7    Bellen, H.J.8
  • 37
    • 27144456598 scopus 로고    scopus 로고
    • Sec15 interacts with Rab11 via a novel domain and affects Rab11 localization in vivo
    • Wu S, Mehta SQ, Pichaud F, Bellen HJ, Quiocho FA. Sec15 interacts with Rab11 via a novel domain and affects Rab11 localization in vivo. Nat Struct Mol Biol 2005; 12: 879-885.
    • (2005) Nat Struct Mol Biol , vol.12 , pp. 879-885
    • Wu, S.1    Mehta, S.Q.2    Pichaud, F.3    Bellen, H.J.4    Quiocho, F.A.5
  • 38
    • 12944298341 scopus 로고    scopus 로고
    • A secreted delta1-Fc fusion protein functions both as an activator and inhibitor of notch1 signaling
    • Hicks C, Ladi E, Lindsell C, Hsieh J, Hayward S, Collazo A, Weinmaster G. A secreted delta1-Fc fusion protein functions both as an activator and inhibitor of notch1 signaling. J Neurosci Res 2002; 69: 60-71.
    • (2002) J Neurosci Res , vol.69 , pp. 60-71
    • Hicks, C.1    Ladi, E.2    Lindsell, C.3    Hsieh, J.4    Hayward, S.5    Collazo, A.6    Weinmaster, G.7
  • 39
    • 0034716909 scopus 로고    scopus 로고
    • Transient notch activation initiates an irreversible switch from neurogenesis to gliogenesis by neural crest stem cells
    • Morrison SJ, Perez SE, Qiao Z, Verdi JM, Hicks C, Weinmaster G, Anderson DJ. Transient notch activation initiates an irreversible switch from neurogenesis to gliogenesis by neural crest stem cells. Cell 2000; 101: 499-510.
    • (2000) Cell , vol.101 , pp. 499-510
    • Morrison, S.J.1    Perez, S.E.2    Qiao, Z.3    Verdi, J.M.4    Hicks, C.5    Weinmaster, G.6    Anderson, D.J.7
  • 40
    • 0034671686 scopus 로고    scopus 로고
    • Notch signaling: From the outside in
    • Mumm JS, Kopan R. Notch signaling: From the outside in. Dev Biol 2000; 228: 151-165.
    • (2000) Dev Biol , vol.228 , pp. 151-165
    • Mumm, J.S.1    Kopan, R.2
  • 41
    • 0033920919 scopus 로고    scopus 로고
    • Notch signal transduction: A real rip and more
    • Weinmaster G. Notch signal transduction: A real rip and more. Curr Opin Genet Dev 2000; 10: 363-369.
    • (2000) Curr Opin Genet Dev , vol.10 , pp. 363-369
    • Weinmaster, G.1
  • 45
    • 6344251643 scopus 로고    scopus 로고
    • Notch subunit heterodimerization and prevention of ligand-independent proteolytic activation depend, respectively, on a novel domain and the LNR repeats
    • Sanchez-Irizarry C, Carpenter AC, Weng AP, Pear WS, Aster JC, Blacklow SC. Notch subunit heterodimerization and prevention of ligand-independent proteolytic activation depend, respectively, on a novel domain and the LNR repeats. Mol Cell Biol 2004; 24: 9265-9273.
    • (2004) Mol Cell Biol , vol.24 , pp. 9265-9273
    • Sanchez-Irizarry, C.1    Carpenter, A.C.2    Weng, A.P.3    Pear, W.S.4    Aster, J.C.5    Blacklow, S.C.6
  • 46
    • 0036273316 scopus 로고    scopus 로고
    • Furin cleavage is not a requirement for Drosophila notch function
    • Kidd S, Lieber T. Furin cleavage is not a requirement for Drosophila notch function. Mech Dev 2002; 115: 41-51.
    • (2002) Mech Dev , vol.115 , pp. 41-51
    • Kidd, S.1    Lieber, T.2
  • 47
    • 33745045658 scopus 로고    scopus 로고
    • Leukemia-associated mutations within the NOTCH1 heterodimerization domain fall into at least two distinct mechanistic classes
    • Malecki MJ, Sanchez-Irizarry C, Mitchell JL, Histen G, Xu ML, Aster JC, Blacklow SC. Leukemia-associated mutations within the NOTCH1 heterodimerization domain fall into at least two distinct mechanistic classes. Mol Cell Biol 2006; 26: 4642-4651.
    • (2006) Mol Cell Biol , vol.26 , pp. 4642-4651
    • Malecki, M.J.1    Sanchez-Irizarry, C.2    Mitchell, J.L.3    Histen, G.4    Xu, M.L.5    Aster, J.C.6    Blacklow, S.C.7
  • 49
    • 33644529627 scopus 로고    scopus 로고
    • Molecular basis of oligoubiquitin-dependent internalization of membrane proteins in mammalian cells
    • Barriere H, Nemes C, Lechardeur D, Khan-Mohammad M, Fruh K, Lukacs GL. Molecular basis of oligoubiquitin-dependent internalization of membrane proteins in mammalian cells. Traffic 2006; 7: 282-297.
    • (2006) Traffic , vol.7 , pp. 282-297
    • Barriere, H.1    Nemes, C.2    Lechardeur, D.3    Khan-Mohammad, M.4    Fruh, K.5    Lukacs, G.L.6
  • 52
    • 28444452974 scopus 로고    scopus 로고
    • Dynamin and the actin cytoskeleton cooperatively regulate plasma membrane invagination by BAR and F-BAR proteins
    • Itoh T, Erdmann KS, Roux A, Habermann B, Werner H, De Camilli P. Dynamin and the actin cytoskeleton cooperatively regulate plasma membrane invagination by BAR and F-BAR proteins. Dev Cell 2005; 9: 791-804.
    • (2005) Dev Cell , vol.9 , pp. 791-804
    • Itoh, T.1    Erdmann, K.S.2    Roux, A.3    Habermann, B.4    Werner, H.5    De Camilli, P.6
  • 53
    • 33745026786 scopus 로고    scopus 로고
    • GTP-dependent twisting of dynamin implicates constriction and tension in membrane fission
    • Roux A, Uyhazi K, Frost A, De Camilli P. GTP-dependent twisting of dynamin implicates constriction and tension in membrane fission. Nature 2006; 441: 528-531.
    • (2006) Nature , vol.441 , pp. 528-531
    • Roux, A.1    Uyhazi, K.2    Frost, A.3    De Camilli, P.4
  • 54
    • 33744523404 scopus 로고    scopus 로고
    • Microfibrillar proteins MAGP-1 and MAGP-2 induce notch1 extracellular domain dissociation and receptor activation
    • Miyamoto A, Lau R, Hein PW, Shipley JM, Weinmaster G. Microfibrillar proteins MAGP-1 and MAGP-2 induce notch1 extracellular domain dissociation and receptor activation. J Biol Chem 2006; 281: 10089-10097.
    • (2006) J Biol Chem , vol.281 , pp. 10089-10097
    • Miyamoto, A.1    Lau, R.2    Hein, P.W.3    Shipley, J.M.4    Weinmaster, G.5
  • 56
    • 0036469994 scopus 로고    scopus 로고
    • Integrity of intracellular domain of notch ligand is indispensable for cleavage required for release of the notch2 intracellular domain
    • Shimizu K, Chiba S, Saito T, Takahashi T, Kumano K, Hamada Y, Hirai H. Integrity of intracellular domain of notch ligand is indispensable for cleavage required for release of the notch2 intracellular domain. EMBO J 2002; 21: 294-302.
    • (2002) EMBO J , vol.21 , pp. 294-302
    • Shimizu, K.1    Chiba, S.2    Saito, T.3    Takahashi, T.4    Kumano, K.5    Hamada, Y.6    Hirai, H.7
  • 60
    • 0442294193 scopus 로고    scopus 로고
    • The lateral signal for LIN-12/notch in C. elegans vulval development comprises redundant secreted and transmembrane DSL proteins
    • Chen N, Greenwald I. The lateral signal for LIN-12/notch in C. elegans vulval development comprises redundant secreted and transmembrane DSL proteins. Dev Cell 2004; 6: 183-192.
    • (2004) Dev Cell , vol.6 , pp. 183-192
    • Chen, N.1    Greenwald, I.2
  • 61
    • 0028027585 scopus 로고
    • GLP-1 is localized to the mitotic region of the C. elegans germ line
    • Crittenden SL, Troemel ER, Evans TC, Kimble J. GLP-1 is localized to the mitotic region of the C. elegans germ line. Development 1994; 120: 2901-2911.
    • (1994) Development , vol.120 , pp. 2901-2911
    • Crittenden, S.L.1    Troemel, E.R.2    Evans, T.C.3    Kimble, J.4
  • 63
    • 0036696444 scopus 로고    scopus 로고
    • The endocytic protein alpha-adaptin is required for numb-mediated asymmetric cell division in Drosophila
    • Berdnik D, Torok T, Gonzalez-Gaitan M, Knoblich JA. The endocytic protein alpha-adaptin is required for numb-mediated asymmetric cell division in Drosophila. Dev Cell 2002; 3: 221-231.
    • (2002) Dev Cell , vol.3 , pp. 221-231
    • Berdnik, D.1    Torok, T.2    Gonzalez-Gaitan, M.3    Knoblich, J.A.4
  • 64
    • 0030199973 scopus 로고    scopus 로고
    • Control of daughter cell fates during asymmetric division: Interaction of numb and notch
    • Guo M, Jan LY, Jan YN. Control of daughter cell fates during asymmetric division: Interaction of numb and notch. Neuron 1996; 17: 27-41.
    • (1996) Neuron , vol.17 , pp. 27-41
    • Guo, M.1    Jan, L.Y.2    Jan, Y.N.3
  • 65
    • 30944462650 scopus 로고    scopus 로고
    • Numb and alpha-adaptin regulate sanpodo endocytosis to specify cell fate in Drosophila external sensory organs
    • Hutterer A, Knoblich JA. Numb and alpha-adaptin regulate sanpodo endocytosis to specify cell fate in Drosophila external sensory organs. EMBO Rep 2005; 6: 836-842.
    • (2005) EMBO Rep , vol.6 , pp. 836-842
    • Hutterer, A.1    Knoblich, J.A.2
  • 66
    • 20144384390 scopus 로고    scopus 로고
    • Lethal giant larvae controls the localization of notch-signaling regulators numb, neuralized, and sanpodo in Drosophila sensory-organ precursor cells
    • Langevin J, Le Borgne R, Rosenfeld F, Gho M, Schweisguth F, Bellaiche Y. Lethal giant larvae controls the localization of notch-signaling regulators numb, neuralized, and sanpodo in Drosophila sensory-organ precursor cells. Curr Biol 2005; 15: 955-962.
    • (2005) Curr Biol , vol.15 , pp. 955-962
    • Langevin, J.1    Le Borgne, R.2    Rosenfeld, F.3    Gho, M.4    Schweisguth, F.5    Bellaiche, Y.6
  • 67
    • 0042442453 scopus 로고    scopus 로고
    • Numb inhibits membrane localization of sanpodo, a four-pass transmembrane protein, to promote asymmetric divisions in Drosophila
    • O'Connor-Giles KM, Skeath JB. Numb inhibits membrane localization of sanpodo, a four-pass transmembrane protein, to promote asymmetric divisions in Drosophila. Dev Cell 2003; 5: 231-243.
    • (2003) Dev Cell , vol.5 , pp. 231-243
    • O'Connor-Giles, K.M.1    Skeath, J.B.2
  • 68
    • 23044506577 scopus 로고    scopus 로고
    • Regulation of membrane localization of sanpodo by lethal giant larvae and neuralized in asymmetrically dividing cells of Drosophila sensory organs
    • Roegiers F, Jan LY, Jan YN. Regulation of membrane localization of sanpodo by lethal giant larvae and neuralized in asymmetrically dividing cells of Drosophila sensory organs. Mol Biol Cell 2005; 16: 3480-3487.
    • (2005) Mol Biol Cell , vol.16 , pp. 3480-3487
    • Roegiers, F.1    Jan, L.Y.2    Jan, Y.N.3
  • 69
    • 0031745685 scopus 로고    scopus 로고
    • The Drosophila sanpodo gene controls sibling cell fate and encodes a tropomodulin homolog, an actin/tropomyosin-associated protein
    • Dye CA, Lee JK, Atkinson RC, Brewster R, Han PL, Bellen HJ. The Drosophila sanpodo gene controls sibling cell fate and encodes a tropomodulin homolog, an actin/tropomyosin-associated protein. Development 1998; 125: 1845-1856.
    • (1998) Development , vol.125 , pp. 1845-1856
    • Dye, C.A.1    Lee, J.K.2    Atkinson, R.C.3    Brewster, R.4    Han, P.L.5    Bellen, H.J.6
  • 70
    • 18644363680 scopus 로고    scopus 로고
    • Density of the notch ligand delta1 determines generation of B and T cell precursors from hematopoietic stem cells
    • Dallas MH, Varnum-Finney B, Delaney C, Kato K, Bernstein ID. Density of the notch ligand delta1 determines generation of B and T cell precursors from hematopoietic stem cells. J Exp Med 2005; 201: 1361-1366.
    • (2005) J Exp Med , vol.201 , pp. 1361-1366
    • Dallas, M.H.1    Varnum-Finney, B.2    Delaney, C.3    Kato, K.4    Bernstein, I.D.5
  • 71
    • 31744445880 scopus 로고    scopus 로고
    • Bearded family members inhibit neuralized-mediated endocytosis and signaling activity of delta in Drosophila
    • Bardin AJ, Schweisguth F. Bearded family members inhibit neuralized-mediated endocytosis and signaling activity of delta in Drosophila. Dev Cell 2006; 10: 245-255.
    • (2006) Dev Cell , vol.10 , pp. 245-255
    • Bardin, A.J.1    Schweisguth, F.2
  • 72
    • 31744431546 scopus 로고    scopus 로고
    • Dorsal-ventral pattern of delta trafficking is established by a Snail-Tom-Neuralized pathway
    • De Renzis S, Yu J, Zinzen R, Wieschaus E. Dorsal-ventral pattern of delta trafficking is established by a Snail-Tom-Neuralized pathway. Dev Cell 2006; 10: 257-264.
    • (2006) Dev Cell , vol.10 , pp. 257-264
    • De Renzis, S.1    Yu, J.2    Zinzen, R.3    Wieschaus, E.4
  • 73
    • 21044444181 scopus 로고    scopus 로고
    • ERK-mediated phosphorylation of Thr735 in TNFalpha-converting enzyme and its potential role in TACE protein trafficking
    • Soond SM, Everson B, Riches DW, Murphy G. ERK-mediated phosphorylation of Thr735 in TNFalpha-converting enzyme and its potential role in TACE protein trafficking. J Cell Sci 2005; 118: 2371-2380.
    • (2005) J Cell Sci , vol.118 , pp. 2371-2380
    • Soond, S.M.1    Everson, B.2    Riches, D.W.3    Murphy, G.4
  • 75
    • 34547136377 scopus 로고    scopus 로고
    • Inhibition of dynamin-dependent endocytosis increases shedding of the amyloid precursor protein ectodomain and reduces generation of amyloid beta protein
    • Carey RM, Balcz BA, Lopez-Coviella I, Slack BE. Inhibition of dynamin-dependent endocytosis increases shedding of the amyloid precursor protein ectodomain and reduces generation of amyloid beta protein. BMC Cell Biol 2005; 6: 30.
    • (2005) BMC Cell Biol , vol.6 , pp. 30
    • Carey, R.M.1    Balcz, B.A.2    Lopez-Coviella, I.3    Slack, B.E.4
  • 76
    • 14244268498 scopus 로고    scopus 로고
    • Gamma-secretase exists on the plasma membrane as an intact complex that accepts substrates and effects intramembrane cleavage
    • Chyung JH, Raper DM, Selkoe DJ. Gamma-secretase exists on the plasma membrane as an intact complex that accepts substrates and effects intramembrane cleavage. J Biol Chem 2005; 280: 4383-4392.
    • (2005) J Biol Chem , vol.280 , pp. 4383-4392
    • Chyung, J.H.1    Raper, D.M.2    Selkoe, D.J.3
  • 77
  • 78
    • 33845542144 scopus 로고    scopus 로고
    • Activation of beta2-adrenergic receptor stimulates gamma-secretase activity and accelerates amyloid plaque formation
    • Ni Y, Zhao X, Bao G, Zou L, Teng L, Wang Z, Song M, Xiong J, Bai Y, Pei G. Activation of beta2-adrenergic receptor stimulates gamma-secretase activity and accelerates amyloid plaque formation. Nat Med 2006; 12: 1390-1396.
    • (2006) Nat Med , vol.12 , pp. 1390-1396
    • Ni, Y.1    Zhao, X.2    Bao, G.3    Zou, L.4    Teng, L.5    Wang, Z.6    Song, M.7    Xiong, J.8    Bai, Y.9    Pei, G.10
  • 79
    • 33750433236 scopus 로고    scopus 로고
    • The Drosophila notch inhibitor and tumor suppressor gene lethal (2) giant discs encodes a conserved regulator of endosomal trafficking
    • Jaekel R, Klein T. The Drosophila notch inhibitor and tumor suppressor gene lethal (2) giant discs encodes a conserved regulator of endosomal trafficking. Dev Cell 2006; 11: 655-669.
    • (2006) Dev Cell , vol.11 , pp. 655-669
    • Jaekel, R.1    Klein, T.2
  • 81
    • 0037040917 scopus 로고    scopus 로고
    • c-Cbl binding and ubiquitin-dependent lysosomal degradation of membrane-associated notch1
    • Jehn BM, Dittert I, Beyer S, von der Mark K, Bielke W. c-Cbl binding and ubiquitin-dependent lysosomal degradation of membrane-associated notch1. J Biol Chem 2002; 277: 8033-8040.
    • (2002) J Biol Chem , vol.277 , pp. 8033-8040
    • Jehn, B.M.1    Dittert, I.2    Beyer, S.3    von der Mark, K.4    Bielke, W.5
  • 83
    • 11144350287 scopus 로고    scopus 로고
    • Drosophila Nedd4 regulates endocytosis of notch and suppresses its ligand-independent activation
    • Sakata T, Sakaguchi H, Tsuda L, Higashitani A, Aigaki T, Matsuno K, Hayashi S. Drosophila Nedd4 regulates endocytosis of notch and suppresses its ligand-independent activation. Curr Biol 2004; 14: 2228-2236.
    • (2004) Curr Biol , vol.14 , pp. 2228-2236
    • Sakata, T.1    Sakaguchi, H.2    Tsuda, L.3    Higashitani, A.4    Aigaki, T.5    Matsuno, K.6    Hayashi, S.7
  • 84
    • 33750530169 scopus 로고    scopus 로고
    • Itch/AIP4 mediates deltex degradation through the formation of K29-linked polyubiquitin chains
    • Chastagner P, Israel A, Brou C. Itch/AIP4 mediates deltex degradation through the formation of K29-linked polyubiquitin chains. EMBO Rep 2006; 7: 1147-1153.
    • (2006) EMBO Rep , vol.7 , pp. 1147-1153
    • Chastagner, P.1    Israel, A.2    Brou, C.3
  • 85
    • 10344263367 scopus 로고    scopus 로고
    • Drosophila deltex mediates suppressor of hairless-independent and late-endosomal activation of notch signaling
    • Hori K, Fostier M, Ito M, Fuwa TJ, Go MJ, Okano H, Baron M, Matsuno K. Drosophila deltex mediates suppressor of hairless-independent and late-endosomal activation of notch signaling. Development 2004; 131: 5527-5537.
    • (2004) Development , vol.131 , pp. 5527-5537
    • Hori, K.1    Fostier, M.2    Ito, M.3    Fuwa, T.J.4    Go, M.J.5    Okano, H.6    Baron, M.7    Matsuno, K.8
  • 87
    • 28544438939 scopus 로고    scopus 로고
    • Endocytic control of epithelial polarity and proliferation in Drosophila
    • Lu H, Bilder D. Endocytic control of epithelial polarity and proliferation in Drosophila. Nat Cell Biol 2005; 7: 1232-1239.
    • (2005) Nat Cell Biol , vol.7 , pp. 1232-1239
    • Lu, H.1    Bilder, D.2
  • 88
    • 33645868635 scopus 로고    scopus 로고
    • The tumor suppressors Merlin and expanded function cooperatively to modulate receptor endocytosis and signaling
    • Maitra S, Kulikauskas RM, Gavilan H, Fehon RG. The tumor suppressors Merlin and expanded function cooperatively to modulate receptor endocytosis and signaling. Curr Biol 2006; 16: 702-709.
    • (2006) Curr Biol , vol.16 , pp. 702-709
    • Maitra, S.1    Kulikauskas, R.M.2    Gavilan, H.3    Fehon, R.G.4
  • 89
    • 0347093486 scopus 로고    scopus 로고
    • Hrs mediates downregulation of multiple signalling receptors in Drosophila
    • Jekely G, Rorth P. Hrs mediates downregulation of multiple signalling receptors in Drosophila. EMBO Rep 2003; 4: 1163-1168.
    • (2003) EMBO Rep , vol.4 , pp. 1163-1168
    • Jekely, G.1    Rorth, P.2
  • 90
    • 33750940206 scopus 로고    scopus 로고
    • Lethal giant discs, a novel C2-domain protein, restricts notch activation during endocytosis
    • Childress JL, Acar M, Tao C, Halder G. Lethal giant discs, a novel C2-domain protein, restricts notch activation during endocytosis. Curr Biol 2006; 16: 2228-2233.
    • (2006) Curr Biol , vol.16 , pp. 2228-2233
    • Childress, J.L.1    Acar, M.2    Tao, C.3    Halder, G.4
  • 91
    • 33750479395 scopus 로고    scopus 로고
    • The conserved c2 domain protein lethal (2) giant discs regulates protein trafficking in Drosophila
    • Gallagher CM, Knoblich JA. The conserved c2 domain protein lethal (2) giant discs regulates protein trafficking in Drosophila. Dev Cell 2006; 11: 641-653.
    • (2006) Dev Cell , vol.11 , pp. 641-653
    • Gallagher, C.M.1    Knoblich, J.A.2
  • 92
    • 27644593284 scopus 로고    scopus 로고
    • Mutations in erupted, the Drosophila ortholog of mammalian tumor susceptibility gene 101, elicit non-cell-autonomous overgrowth
    • Moberg KH, Schelble S, Burdick SK, Hariharan IK. Mutations in erupted, the Drosophila ortholog of mammalian tumor susceptibility gene 101, elicit non-cell-autonomous overgrowth. Dev Cell 2005; 9: 699-710.
    • (2005) Dev Cell , vol.9 , pp. 699-710
    • Moberg, K.H.1    Schelble, S.2    Burdick, S.K.3    Hariharan, I.K.4
  • 93
    • 27644498439 scopus 로고    scopus 로고
    • Tumor suppressor properties of the ESCRT-II complex component Vps25 in Drosophila
    • Thompson BJ, Mathieu J, Sung HH, Loeser E, Rorth P, Cohen SM. Tumor suppressor properties of the ESCRT-II complex component Vps25 in Drosophila. Dev Cell 2005; 9: 711-720.
    • (2005) Dev Cell , vol.9 , pp. 711-720
    • Thompson, B.J.1    Mathieu, J.2    Sung, H.H.3    Loeser, E.4    Rorth, P.5    Cohen, S.M.6
  • 94
    • 27644568520 scopus 로고    scopus 로고
    • The Drosophila tumor suppressor vps25 prevents nonautonomous overproliferation by regulating notch trafficking
    • Vaccari T, Bilder D. The Drosophila tumor suppressor vps25 prevents nonautonomous overproliferation by regulating notch trafficking. Dev Cell 2005; 9: 687-698.
    • (2005) Dev Cell , vol.9 , pp. 687-698
    • Vaccari, T.1    Bilder, D.2


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