-
1
-
-
33644826473
-
Roots and stems: Stem cells in cancer
-
Polyak K, Hahn WC. Roots and stems: Stem cells in cancer. Nat Med 2006;12:296-300.
-
(2006)
Nat Med
, vol.12
, pp. 296-300
-
-
Polyak, K.1
Hahn, W.C.2
-
2
-
-
33644560281
-
Cancer stem cells: An old idea - A paradigm shift
-
Wicha MS, Liu S, Dontu G. Cancer stem cells: An old idea - A paradigm shift. Cancer Res 2006;66:1883-1890.
-
(2006)
Cancer Res
, vol.66
, pp. 1883-1890
-
-
Wicha, M.S.1
Liu, S.2
Dontu, G.3
-
3
-
-
27644590041
-
A new Notch in the HIF belt: How hypoxia impacts differentiation
-
Cejudo-Martin P, Johnson RS. A new Notch in the HIF belt: How hypoxia impacts differentiation. Dev Cell 2005;9:575-576.
-
(2005)
Dev Cell
, vol.9
, pp. 575-576
-
-
Cejudo-Martin, P.1
Johnson, R.S.2
-
4
-
-
33644747418
-
HIF-2alpha regulates Oct-4: Effects of hypoxia on stem cell function, embryonic development, and tumor growth
-
Covello KL, Kehler J, Yu H et al. HIF-2alpha regulates Oct-4: Effects of hypoxia on stem cell function, embryonic development, and tumor growth. Genes Dev 2006;20:557-570.
-
(2006)
Genes Dev
, vol.20
, pp. 557-570
-
-
Covello, K.L.1
Kehler, J.2
Yu, H.3
-
5
-
-
0034901617
-
Hypoxia-inducible factor and the development of stem cells of the cardiovascular system
-
Ramirez-Bergeron DL, Simon MC. Hypoxia-inducible factor and the development of stem cells of the cardiovascular system. STEM CELLS 2001;19:279-286.
-
(2001)
STEM CELLS
, vol.19
, pp. 279-286
-
-
Ramirez-Bergeron, D.L.1
Simon, M.C.2
-
6
-
-
24344440832
-
Hypoxia-induced dedifferentiation of tumor cells - A mechanism behind heterogeneity and aggressiveness of solid tumors
-
Axelson H, Fredlund E, Ovenberger M et al. Hypoxia-induced dedifferentiation of tumor cells - A mechanism behind heterogeneity and aggressiveness of solid tumors. Semin Cell Dev Biol 2005;16:554-563.
-
(2005)
Semin Cell Dev Biol
, vol.16
, pp. 554-563
-
-
Axelson, H.1
Fredlund, E.2
Ovenberger, M.3
-
7
-
-
85047692887
-
Expansion of human SCID-repopulating cells under hypoxic conditions
-
Danet GH, Pan Y, Luongo JL et al. Expansion of human SCID-repopulating cells under hypoxic conditions. J Clin Invest 2003;112:126-135.
-
(2003)
J Clin Invest
, vol.112
, pp. 126-135
-
-
Danet, G.H.1
Pan, Y.2
Luongo, J.L.3
-
8
-
-
0027443181
-
The role of hypoxia in the maintenance of hematopoietic stem cells
-
Cipolleschi MG, Dello Sbarba P, Olivotto M. The role of hypoxia in the maintenance of hematopoietic stem cells. Blood 1993;82:2031-2037.
-
(1993)
Blood
, vol.82
, pp. 2031-2037
-
-
Cipolleschi, M.G.1
Dello Sbarba, P.2
Olivotto, M.3
-
9
-
-
27644561755
-
Hypoxia requires Notch signaling to maintain the undifferentiated cell state
-
Gustafsson MV, Zheng X, Pereira T et al. Hypoxia requires Notch signaling to maintain the undifferentiated cell state. Dev Cell 2005;9:617-628.
-
(2005)
Dev Cell
, vol.9
, pp. 617-628
-
-
Gustafsson, M.V.1
Zheng, X.2
Pereira, T.3
-
10
-
-
22444447491
-
Hematopoietic stem cells and their niche
-
Suda T, Arai F, Hirao A. Hematopoietic stem cells and their niche. Trends Immunol 2005;26:426-433.
-
(2005)
Trends Immunol
, vol.26
, pp. 426-433
-
-
Suda, T.1
Arai, F.2
Hirao, A.3
-
11
-
-
33744926266
-
Quantitative proteomics reveals post-translational control as a regulatory factor in primary hematopoietic stem cells
-
Unwin RD, Smith DL, Blinco D et al. Quantitative proteomics reveals post-translational control as a regulatory factor in primary hematopoietic stem cells. Blood 2006;107:4687-4694.
-
(2006)
Blood
, vol.107
, pp. 4687-4694
-
-
Unwin, R.D.1
Smith, D.L.2
Blinco, D.3
-
12
-
-
0035871882
-
Spatial localization of transplanted hemopoietic stem cells: Inferences for the localization of stem cell niches
-
Nilsson SK, Johnston HM, Coverdale JA. Spatial localization of transplanted hemopoietic stem cells: Inferences for the localization of stem cell niches. Blood 2001;97:2293-2299.
-
(2001)
Blood
, vol.97
, pp. 2293-2299
-
-
Nilsson, S.K.1
Johnston, H.M.2
Coverdale, J.A.3
-
13
-
-
2642526992
-
The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme
-
Krishnamurthy P, Ross DD, Nakanishi T et al. The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme. J Biol Chem 2004;279:24218-24225.
-
(2004)
J Biol Chem
, vol.279
, pp. 24218-24225
-
-
Krishnamurthy, P.1
Ross, D.D.2
Nakanishi, T.3
-
14
-
-
0033581704
-
The p66Shc adaptor protein controls oxidative stress response and life span in mammals
-
Migliaccio E, Giorgio M, Mele S et al. The p66Shc adaptor protein controls oxidative stress response and life span in mammals. Nature 1999;402:309-313.
-
(1999)
Nature
, vol.402
, pp. 309-313
-
-
Migliaccio, E.1
Giorgio, M.2
Mele, S.3
-
15
-
-
33747623018
-
Notch signalling: A simple pathway becomes complex
-
Bray SJ. Notch signalling: A simple pathway becomes complex. Nat Rev Mol Cell Biol 2006;7:678-689.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 678-689
-
-
Bray, S.J.1
-
16
-
-
4344699403
-
Role of carbonic anhydrase IX in human tumor cell growth, survival, and invasion
-
Robertson N, Potter C, Harris AL. Role of carbonic anhydrase IX in human tumor cell growth, survival, and invasion. Cancer Res 2004;64:6160-6165.
-
(2004)
Cancer Res
, vol.64
, pp. 6160-6165
-
-
Robertson, N.1
Potter, C.2
Harris, A.L.3
-
17
-
-
0037948854
-
In vitro propagation and transcriptional profiling of human mammar stem/progenitor cells
-
Dontu G, Abdallah WM, Foley JM et al. In vitro propagation and transcriptional profiling of human mammar stem/progenitor cells. Genes Dev 2003;17:1253-1270.
-
(2003)
Genes Dev
, vol.17
, pp. 1253-1270
-
-
Dontu, G.1
Abdallah, W.M.2
Foley, J.M.3
-
18
-
-
18944375734
-
Role of Notch signaling in cell-fate determination of human mammary stem/progenitor cells
-
Dontu G, Jackson KW, McNicholas E et al. Role of Notch signaling in cell-fate determination of human mammary stem/progenitor cells. Breast Cancer Res 2004;6:R605-R615.
-
(2004)
Breast Cancer Res
, vol.6
-
-
Dontu, G.1
Jackson, K.W.2
McNicholas, E.3
-
19
-
-
0036359548
-
Hypoxia - A key regulatory factor in tumour growth
-
Harris AL. Hypoxia - A key regulatory factor in tumour growth. Nat Rev Cancer 2002;2:38-47.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 38-47
-
-
Harris, A.L.1
-
20
-
-
33745728170
-
Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells
-
Liu S, Dontu G, Mantle ID et al. Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells. Cancer Res 2006;66:6063-6071.
-
(2006)
Cancer Res
, vol.66
, pp. 6063-6071
-
-
Liu, S.1
Dontu, G.2
Mantle, I.D.3
-
21
-
-
21344454219
-
Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties
-
Ponti D, Costa A, Zaffaroni N et al. Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties. Cancer Res 2005;65:5506-55011.
-
(2005)
Cancer Res
, vol.65
, pp. 5506-55011
-
-
Ponti, D.1
Costa, A.2
Zaffaroni, N.3
-
22
-
-
0036534444
-
Isoform-specific knockdown and expression of adaptor protein ShcA using small interfering RNA
-
Kisielow M, Kleinerm S, Nagasawa M et al. Isoform-specific knockdown and expression of adaptor protein ShcA using small interfering RNA. Biochem J 2002;363:1-5.
-
(2002)
Biochem J
, vol.363
, pp. 1-5
-
-
Kisielow, M.1
Kleinerm, S.2
Nagasawa, M.3
-
23
-
-
33645877676
-
Correlation between formamidopyrimidine DNA glycosylase (Fpg)-sensitive sites determined by a comet assay, increased MDA, and decreased glutathione during long exposure to thinner inhalation
-
Martinez-Alfaro M, Palma-Tirado L, Sandoval-Zapata F et al. Correlation between formamidopyrimidine DNA glycosylase (Fpg)-sensitive sites determined by a comet assay, increased MDA, and decreased glutathione during long exposure to thinner inhalation. Toxicol Lett 2006;163:198-205.
-
(2006)
Toxicol Lett
, vol.163
, pp. 198-205
-
-
Martinez-Alfaro, M.1
Palma-Tirado, L.2
Sandoval-Zapata, F.3
-
24
-
-
0037270299
-
Immunotargeting of human cervical carcinoma xenograft expressing CA IX tumor-associated antigen by 125I-labeled M75 monoclonal antibody
-
Chrastina A, Pastorekova S, Pastorek J. Immunotargeting of human cervical carcinoma xenograft expressing CA IX tumor-associated antigen by 125I-labeled M75 monoclonal antibody. Neoplasma 2003;50:13-21.
-
(2003)
Neoplasma
, vol.50
, pp. 13-21
-
-
Chrastina, A.1
Pastorekova, S.2
Pastorek, J.3
-
25
-
-
33645751939
-
Cross talk among Notch3, pre-TCR, and Tal1 in T-cell development and leukemogenesis
-
Talora C, Cialfi S, Oliviero C et al. Cross talk among Notch3, pre-TCR, and Tal1 in T-cell development and leukemogenesis. Blood 2006;107:3313-3320.
-
(2006)
Blood
, vol.107
, pp. 3313-3320
-
-
Talora, C.1
Cialfi, S.2
Oliviero, C.3
-
26
-
-
30044437912
-
The role of extracellular signal-regulated protein kinase in transcriptional regulation of the hypoxia marker carbonic anhydrase IX
-
Kaluz S, Kaluzova M, Stanbridge EJ. The role of extracellular signal-regulated protein kinase in transcriptional regulation of the hypoxia marker carbonic anhydrase IX. J Cell Biochem 2006;97:207-216.
-
(2006)
J Cell Biochem
, vol.97
, pp. 207-216
-
-
Kaluz, S.1
Kaluzova, M.2
Stanbridge, E.J.3
-
27
-
-
24944506696
-
High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival
-
Reedijk M, Odorcic S, Chang L et al. High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival. Cancer Res 2005;65:8530-8537.
-
(2005)
Cancer Res
, vol.65
, pp. 8530-8537
-
-
Reedijk, M.1
Odorcic, S.2
Chang, L.3
-
28
-
-
0035881075
-
Prognostic significance of a novel hypoxia-regulated marker, carbonic anhydrase IX, in invasive breast carcinoma
-
Chia SK, Wykoff CC, Watson PH et al. Prognostic significance of a novel hypoxia-regulated marker, carbonic anhydrase IX, in invasive breast carcinoma. J Clin Oncol 2001;19:3660-3668.
-
(2001)
J Clin Oncol
, vol.19
, pp. 3660-3668
-
-
Chia, S.K.1
Wykoff, C.C.2
Watson, P.H.3
-
29
-
-
0034099236
-
Elevated levels of p66 Shc are found in breast cancer cell lines and primary tumors with high metastatic potential
-
Jackson JG, Yoneda T, Clark GM et al. Elevated levels of p66 Shc are found in breast cancer cell lines and primary tumors with high metastatic potential. Clin Cancer Res 2000;6:1135-1139.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 1135-1139
-
-
Jackson, J.G.1
Yoneda, T.2
Clark, G.M.3
-
30
-
-
30044449425
-
Rac1 leads to phosphorylation-dependent increase in stability of the p66Shc adaptor protein: Role in Rac1-induced oxidative stress
-
Khanday FA, Yamamori T, Mattagajasingh I et al. Rac1 leads to phosphorylation-dependent increase in stability of the p66Shc adaptor protein: Role in Rac1-induced oxidative stress. Mol Biol Cell 2006;17:122-129.
-
(2006)
Mol Biol Cell
, vol.17
, pp. 122-129
-
-
Khanday, F.A.1
Yamamori, T.2
Mattagajasingh, I.3
-
31
-
-
23244452354
-
Stem cell depletion through epidermal deletion of Rac1
-
Benitah SA, Fryem M, Glogauer M et al. Stem cell depletion through epidermal deletion of Rac1. Science 2005;309:933-935.
-
(2005)
Science
, vol.309
, pp. 933-935
-
-
Benitah, S.A.1
Fryem, M.2
Glogauer, M.3
-
32
-
-
0000055057
-
Pleiotropy, natural selection, and the evolution of senescence
-
Williams GC. Pleiotropy, natural selection, and the evolution of senescence. Evolution 1957;11:398-411.
-
(1957)
Evolution
, vol.11
, pp. 398-411
-
-
Williams, G.C.1
|