Integrative genomic analyses on GLI1: Positive regulation of GLI1 by Hedgehog-GLI, TGFβ-Smads, and RTK-PI3K-AKTsignals, and negative regulation of GLI1 by Notch-CSL-HES/HEY, and GPCR-Gs-PKA signals

International Journal of Oncology

Volumn 35, Issue 1, 2009, Pages 187-192

  Katoh, Yuriko ^a   Katoh, Masaru ^b  

^a M&M Medical BioInformatics   (Japan)

^b NATIONAL CANCER CENTER   (Japan)

Author keywords

Bioinformatics; Breast cancer; Gastric cancer; Hedgehog; Pancreatic cancer; Peritoneal dissemination; Personalized medicine; Pleural dissemination; Systems biology; TGF

Indexed keywords

CELL PROTEIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; DOUBLE STRANDED RNA; G PROTEIN COUPLED RECEPTOR; NOTCH RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN ARHGAP9; PROTEIN CSL; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; SMAD PROTEIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GLI1; TRANSCRIPTION FACTOR HES; TRANSCRIPTION FACTOR HEY; TRANSCRIPTION FACTOR SLUG; TRANSCRIPTION FACTOR SNAIL; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ARTICLE; BONE MARROW; CHIMPANZEE; CONTROLLED STUDY; GENE EXPRESSION REGULATION; GENE LOCATION; GENETIC CONSERVATION; GENOME ANALYSIS; HUMAN; MACROPHAGE; MONOCYTE; MOUSE; NEGATIVE FEEDBACK; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; NUCLEOTIDE SEQUENCE; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; SPECIES COMPARISON; SPLEEN; THYMUS; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION REGULATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BASE SEQUENCE; CONSERVED SEQUENCE; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DATABASES, NUCLEIC ACID; GENE REGULATORY NETWORKS; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; GTPASE-ACTIVATING PROTEINS; HEDGEHOG PROTEINS; HUMANS; IMMUNOGLOBULIN J RECOMBINATION SIGNAL SEQUENCE-BINDING PROTEIN; MOLECULAR SEQUENCE DATA; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; SMAD PROTEINS; TRANSCRIPTION FACTORS; TRANSFORMING GROWTH FACTOR BETA;

EID: 67649446810     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo_00000328     Document Type: Article

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