Inhibition of Dll4-mediated signaling induces proliferation of immature vessels and results in poor tissue perfusion

Blood

Volumn 109, Issue 11, 2007, Pages 4753-4760

  Scehnet, Jeffrey S ^a   Jiang, Weidong ^b   Kumar, S Ram ^a   Krasnoperov, Valery ^b   Trindade, Alexandre ^c,d   Benedito, Rui ^c,d   Djokovic, Dusan ^c,d   Borges, Cristina ^c,d   Ley, Eric J ^a   Duarte, Antonio ^c,d   Gill, Parkash S ^a,e  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b Vasgene Therapeutics   (United States)

^c INSTITUTO SUPERIOR DE AGRONOMIA   (Portugal)

^d INSTITUTO GULBENKIAN DE CIÊNCIA   (Portugal)

^e UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DLL4 PROTEIN; MEMBRANE PROTEIN; NOTCH RECEPTOR; UNCLASSIFIED DRUG;

ALLELE; ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL; BLOOD VESSEL DIAMETER; BLOOD VESSEL REACTIVITY; CANCER GRAFT; CELL MATURATION; CELL PROLIFERATION; CONTROLLED STUDY; EMBRYO; FEMALE; GENE DELETION; GENE EXPRESSION; GENE FUNCTION; GENE TARGETING; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; MATURATION; MOUSE; NONHUMAN; PERFUSION; PERICYTE; PRIORITY JOURNAL; PROTEIN DOMAIN; TISSUE PERFUSION; TUMOR GROWTH; TUMOR VASCULARIZATION;

EID: 34247479498     PISSN: 00064971     EISSN: 00064971     Source Type: Journal    
DOI: 10.1182/blood-2006-12-063933     Document Type: Article

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