The intracellular region of Notch ligands: Does the tail make the difference?

Biology Direct

Volumn 2, Issue , 2007, Pages

  Pintar, Alessandro ^a   De Biasio, Alfredo ^a   Popovic, Matija ^a   Ivanova, Neli ^a   Pongor, Sándor ^a  

^a INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

MAMMALIA;

EID: 34548542102     PISSN: None     EISSN: 17456150     Source Type: Journal    
DOI: 10.1186/1745-6150-2-19     Document Type: Review

References (50)

1. Ehebauer M Hayward P Arias AM Notch, a universal arbiter of cell fate decisions Science 2006, 314:1414-1415 10.1126/science.1134042 17138893
2. Weinmaster G Notch signal transduction: A real rip and more Curr Opin Genet Dev 2000, 10:363-369 10.1016/S0959-437X(00)00097-6 10889061
3. Rehman AO Wang CY Notch signaling in the regulation of tumor angiogenesis Trends Cell Biol 2006, 16:293-300 10.1016/j.tcb.2006.04.003 16697642
4. Osborne BA Minter LM Notch signalling during peripheral T-cell activation and differentiation Nat Rev Immunol 2007, 7:64-75 10.1038/ nri1998 17170755
5. Chiba S Notch signaling in stem cell systems Stem Cells 2006, 24:2437-2447 10.1634/stemcells.2005-0661 16888285
6. Gridley T Notch signaling and inherited disease syndromes Hum Mol Genet 2003, 12:R9-13 10.1093/hmg/ddg052 12668592
7. Roy M Pear WS Aster JC The multifaceted role of Notch in cancer Curr Opin Genet Dev 2007, 17:52-59 10.1016/j.gde.2006.12.001 17178457
8. Miele L Golde T Osborne B Notch signaling in cancer Curr Mol Med 2006, 6:905-918 10.2174/156652406779010830 17168741
9. Shih Ie M Wang TL Notch signaling, gamma-secretase inhibitors, and cancer therapy Cancer Res 2007, 67:1879-1882 10.1158/ 0008-5472.CAN-06-3958 17332312
10. Miele L Miao H Nickoloff BJ NOTCH signaling as a novel cancer therapeutic target Curr Cancer Drug Targets 2006, 6:313-323 10.2174/ 156800906777441771 16848722
11. Costa RM Drew C Silva AJ Notch to remember Trends Neurosci 2005, 28:429-435 10.1016/j.tins.2005.05.003 15922461
12. Le Borgne R Regulation of Notch signalling by endocytosis and endosomal sorting Curr Opin Cell Biol 2006 18 213 222 10.1016/j.ceb.2006.02.011 16488590
13. Haines N Irvine KD Glycosylation regulates Notch signalling Nat Rev Mol Cell Biol 2003, 4: 786-797 14570055
14. Sundaram MV The love-hate relationship between Ras and Notch Genes Dev 2005, 19:1825-1839 10.1101/gad.1330605 16103211
15. Kluppel M Wrana JL Turning it up a Notch: Cross-talk between TGF beta and Notch signaling Bioessays 2005, 27:115-118 10.1002/bies.20187 15666349
16. Letunic I Copley RR Pils B Pinkert S Schultz J Bork P SMART 5: Domains in the context of genomes and networks Nucleic Acids Res 2006, 34:D257-60 1347442 16381859 10.1093/nar/gkj079
17. Popovic M Coglievina M Guarnaccia C Verdone G Esposito G Pintar A Pongor S Gene synthesis, expression, purification, and characterization of human Jagged-1 intracellular region Protein Expr Purif 2006, 47:398-404 10.1016/j.pep.2005.11.027 16427310
18. Hock B Bohme B Karn T Yamamoto T Kaibuchi K Holtrich U Holland S Pawson T Rubsamen-Waigmann H Strebhardt K PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor Proc Natl Acad Sci U S A 1998, 95:9779-9784 21413 9707552 10.1073/pnas.95.17.9779
19. Ascano JM Beverly LJ Capobianco AJ The C-terminal PDZ-ligand of JAGGED1 is essential for cellular transformation J Biol Chem 2003, 278:8771-8779 10.1074/jbc.M211427200 12496248
20. Six EM Ndiaye D Sauer G Laabi Y Athman R Cumano A Brou C Israel A Logeat F The notch ligand Delta1 recruits Dlg1 at cell-cell contacts and regulates cell migration J Biol Chem 2004, 279:55818-55826 10.1074/ jbc.M408022200 15485825
21. Wright GJ Leslie JD Ariza-McNaughton L Lewis J Delta proteins and MAGI proteins: An interaction of Notch ligands with intracellular scaffolding molecules and its significance for zebrafish development Development 2004, 131:5659-5669 10.1242/dev.01417 15509766
22. Pfister S Przemeck GK Gerber JK Beckers J Adamski J Hrabe de Angelis M Interaction of the MAGUK family member Acvrinp1 and the cytoplasmic domain of the Notch ligand Delta1 J Mol Biol 2003, 333;229-235 10.1016/ j.jmb.2003.08.043 14529612
23. Beuming T Skrabanek L Niv MY Mukherjee P Weinstein H PDZBase: A protein-protein interaction database for PDZ-domains Bioinformatics 2005, 21:827-828 10.1093/bioinformatics/bti098 15513994
24. Basdevant N Weinstein H Ceruso M Thermodynamic basis for promiscuity and selectivity in protein-protein interactions: PDZ domains, a case study J Am Chem Soc 2006, 128:12766-12777 10.1021/ja060830y 17002371
25. Wiedemann U Boisguerin P Leben R Leitner D Krause G Moelling K Volkmer-Engert R Oschkinat H Quantification of PDZ domain specificity, prediction of ligand affinity and rational design of super-binding peptides J Mol Biol 2004, 343:703-718 10.1016/j.jmb.2004.08.064 15465056
26. Gordon WR Vardar-Ulu D Histen G Sanchez-Irizarry C Aster JC Blacklow SC Structural basis for autoinhibition of Notch Nat Struct Mol Biol 2007, 14;295-300 10.1038/nsmb1227 17401372
27. Nichols JT Miyamoto A Olsen SL D'Souza B Yao C Weinmaster G DSL ligand endocytosis physically dissociates Notch1 heterodimers before activating proteolysis can occur J Cell Biol 2007, 176:445-458 10.1083/ jcb.200609014 17296795
28. Koo BK Lim HS Song R Yoon MJ Yoon KJ Moon JS Kim YW Kwon MC Yoo KW Kong MP Lee J Chitnis AB Kim CH Kong YY Mind bomb 1 is essential for generating functional Notch ligands to activate Notch Development 2005, 132:3459-3470 10.1242/dev.01922 16000382
29. Barsi JC Rajendra R Wu JI Artzt K Mind bomb1 is a ubiquitin ligase essential for mouse embryonic development and Notch signaling Mech Dev 2005, 122:1106-1117 10.1016/j.mod.2005.06.005 16061358
30. Koo BK Yoon KJ Yoo KW Lim HS Song R So JH Kim CH Kong YY Mind bomb-2 is an E3 ligase for Notch ligand J Biol Chem 2005, 280:22335-22342 10.1074/ jbc.M501631200 15824097
31. Takeuchi T Adachi Y Ohtsuki Y Skeletrophin, a novel ubiquitin ligase to the intracellular region of Jagged-2, is aberrantly expressed in multiple myeloma Am J Pathol 2005, 166:1817-1826 1602431 15920166
32. Vollrath B Pudney J Asa S Leder P Fitzgerald K Isolation of a murine homologue of the Drosophila neuralized gene, a gene required for axonemal integrity in spermatozoa and terminal maturation of the mammary gland Mol Cell Biol 2001, 21:7481-7494 99920 11585928 10.1128/ MCB.21.21.7481-7494.2001
33. Ruan Y Tecott L Jiang MM Jan LY Jan YN Ethanol hypersensitivity and olfactory discrimination defect in mice lacking a homolog of Drosophila neuralized Proc Natl Acad Sci U S A 2001, 98:9907-9912 55551 11481456 10.1073/pnas.171321098
34. Song R Koo BK Yoon KJ Yoon MJ Yoo KW Kim HT Oh HJ Kim YY Han JK Kim CH Kong YY Neuralized-2 regulates a Notch ligand in cooperation with Mind bomb-1 J Biol Chem 2006, 281:36391-36400 10.1074/jbc.M606601200 17003037
35. Itoh M Kim CH Palardy G Oda T Jiang YJ Maust D Yeo SY Lorick K Wright GJ Ariza-McNaughton L Weissman AM Lewis J Chandrasekharappa SC Chitnis AB Mind bomb is a ubiquitin ligase that is essential for efficient activation of Notch signaling by Delta Dev Cell 2003, 4:67-82 10.1016/ S1534-5807(02)00409-4 12530964
36. Wang W Struhl G Drosophila Epsin mediates a select endocytic pathway that DSL ligands must enter to activate Notch Development 2004, 131:5367-5380 10.1242/dev.01413 15469974
37. Six E Ndiaye D Laabi Y Brou C Gupta-Rossi N Israel A Logeat F The Notch ligand Delta1 is sequentially cleaved by an ADAM protease and gamma-secretase Proc Natl Acad Sci USA 2003, 100:7638-7643 164639 12794186 10.1073/pnas.1230693100
38. LaVoie MJ Selkoe DJ The Notch ligands, Jagged and Delta, are sequentially processed by alpha-secretase and presenilin/gamma-secretase and release signaling fragments J Biol Chem 2003, 278:34427-34437 10.1074/jbc.M302659200 12826675
39. Ikeuchi T Sisodia SS The Notch ligands, Delta1 and Jagged2, are substrates for presenilin-dependent "gamma-secretase" cleavage J Biol Chem 2003 278 7751 7754 10.1074/jbc.C200711200 12551931
40. Hiratochi M Nagase H Kuramochi Y Koh CS Ohkawara T Nakayama K The Delta intracellular domain mediates TGF-beta/Activin signaling through binding to Smads and has an important bi-directional function in the Notch-Delta signaling pathway Nucleic Acids Res 2007, 35:912-922 1807952 17251195 10.1093/nar/gkl1128
41. Kumar S Tamura K Nei M MEGA3: Integrated software for Molecular Evolutionary Genetics Analysis and sequence alignment Brief Bioinform 2004, 5:150-163 10.1093/bib/5.2.150 15260895
42. Notredame C Higgins DG Heringa J T-Coffee: A novel method for fast and accurate multiple sequence alignment J Mol Biol 2000, 302:205-217 10.1006/jmbi.2000.4042 10964570
43. Edgar RC MUSCLE: Multiple sequence alignment with high accuracy and high throughput Nucleic Acids Res 2004, 32:1792-1797 390337 15034147 10.1093/ nar/gkh340
44. Uversky VN Gillespie JR Fink AL Why are "natively unfolded" proteins unstructured under physiologic conditions? Proteins 2000, 41:415-427 10.1002/ 1097-0134(20001115)41:3<415::AID-PROT130>3.0.CO;2-7 11025552
45. Linding R Jensen LJ Diella F Bork P Gibson TJ Russell RB Protein disorder prediction: Implications for structural proteomics Structure 2003, 11:1453-1459 10.1016/j.str.2003.10.002 14604535
46. Blom N Gammeltoft S Brunak S Sequence and structure-based prediction of eukaryotic protein phosphorylation sites J Mol Biol 1999, 294:1351-1362 10.1006/jmbi.1999.3310 10600390
47. Puntervoll P Linding R Gemund C Chabanis-Davidson S Mattingsdal M Cameron S Martin DM Ausiello G Brannetti B Costantini A Ferre F Maselli V Via A Cesareni G Diella F Superti-Furga G Wyrwicz L Ramu C McGuigan C Gudavalli R Letunic I Bork P Rychlewski L Kuster B Helmer-Citterich M Hunter WN Aasland R Gibson TJ ELM server: A new resource for investigating short functional sites in modular eukaryotic proteins Nucleic Acids Res 2003, 31:3625-3630 168952 12824381 10.1093/nar/gkg545
48. Gupta R Brunak S Prediction of glycosylation across the human proteome and the correlation to protein function Pac Symp Biocomput 2002:310-22 11928486
49. Catic A Collins C Church GM Ploegh HL Preferred in vivo ubiquitination sites Bioinformatics 2004, 20:3302-3307 10.1093/bioinformatics/bth407 15256413
50. Shannon P Markiel A Ozier O Baliga NS Wang JT Ramage D Amin N Schwikowski B Ideker T Cytoscape: A software environment for integrated models of biomolecular interaction networks Genome Res 2003, 13:2498-2504 403769 14597658 10.1101/gr.1239303