Notch1 signaling promotes primary melanoma progression by activating mitogen-activated protein kinase/phosphatidylinositol 3-kinase-Akt pathways and up-regulating N-cadherin expression

Cancer Research

Volumn 66, Issue 8, 2006, Pages 4182-4190

  Liu, Zhao Jun ^a   Xiao, Min ^a   Balint, Klara ^a,b   Smalley, Keiran S M ^a   Brafford, Patricia ^a   Qiu, Ruihua ^a   Pinnix, Chelsea C ^a   Li, Xueli ^a   Herlyn, Meenhard ^a  

^a WISTAR INSTITUTE   (United States)

^b UNIVERSITY OF DEBRECEN   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; NERVE CELL ADHESION MOLECULE; NOTCH1 RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CANCER INVASION; CANCER SURVIVAL; CELL ADHESION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG INHIBITION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MELANOMA; METASTASIS; MOUSE; NONHUMAN; ONCOGENE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; ANTIGENS, CD; CADHERINS; CELL ADHESION; CELL GROWTH PROCESSES; CELL LINE, TUMOR; DISEASE PROGRESSION; DNA-BINDING PROTEINS; ENZYME ACTIVATION; HUMANS; MAP KINASE SIGNALING SYSTEM; MELANOMA; MICE; MICE, SCID; MITOGEN-ACTIVATED PROTEIN KINASES; NUCLEAR PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, NOTCH1; SPHEROIDS, CELLULAR; UP-REGULATION;

EID: 33646257783     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-05-3589     Document Type: Article

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