Mammalian Numb proteins promote Notch1 receptor ubiquitination and degradation of the Notch1 intracellular domain

Journal of Biological Chemistry

Volumn 278, Issue 25, 2003, Pages 23196-23203

  McGill, Melanie A ^b   McGlade, C Jane ^a  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; BIOLOGICAL MEMBRANES; ENZYME INHIBITION; GENES; PROTEINS;

SIGNALING PATHWAYS;

BIOCHEMISTRY;

LIGASE; LUCIFERASE; MEMBRANE PROTEIN; NOTCH RECEPTOR; NOTCH1 RECEPTOR; PHOSPHOTYROSINE; PROTEIN; PROTEIN ITCH; PROTEIN NUMB; RECEPTOR PROTEIN; TRANSCRIPTION FACTOR HES 1; UBIQUITIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CYTOSOL; DOWN REGULATION; EMBRYO; GENE TARGETING; HUMAN; HUMAN CELL; MAMMAL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

3T3 CELLS; ANIMALS; BINDING SITES; CELL LINE; CYSTEINE ENDOPEPTIDASES; DROSOPHILA; HUMANS; MAMMALS; MEMBRANE PROTEINS; MICE; MULTIENZYME COMPLEXES; MUTAGENESIS, SITE-DIRECTED; NERVE TISSUE PROTEINS; PROTEASOME ENDOPEPTIDASE COMPLEX; RECEPTOR, NOTCH1; RECEPTORS, CELL SURFACE; RECOMBINANT PROTEINS; TRANSCRIPTION FACTORS; TRANSFECTION; UBIQUITIN;

ANIMALIA; MAMMALIA;

EID: 0037663379     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M302827200     Document Type: Article

References (53)

1. Rhyu, M. S., Jan, L. Y., and Jan, Y. N. (1994) Cell 76, 477-491
2. Ruiz, G. M., and Bate, M. (1997) Development 124, 4857-4866
3. Spana, E. P., and Doe, C. Q. (1996) Neuron 17, 21-26
4. Uemura, T., Shepherd, S., Ackerman, L., Jan, L. Y., and Jan, Y. N. (1989) Cell 58, 349-360
5. Knoblich, J. A., Jan, L. Y., and Jan, Y. N. (1995) Nature 377, 624-627
6. Spana, E. P., Kopczynski, C., Goodman, C. S., and Doe, C. Q. (1995) Development 121, 3489-3494
7. Zhong, W., Feder, J. N., Jiang, M. M., Jan, L. Y., and Jan, Y. N. (1996) Neuron 17, 43-53
8. Guo, M., Jan, L. Y., and Jan, Y. N. (1996) Neuron 17, 27-41
9. Verdi, J. M., Schmandt, R., Bashirullah, A., Jacob, S., Salvino, R., Craig, C. G., Program, A. E., Lipshitz, H. D., and McGlade, C. J. (1996) Curr. Biol. 6, 1134-1145
10. Zhong, W., Jiang, M. M., Schonemann, M. D., Meneses, J. J., Pedersen, R. A., Jan, L. Y., and Jan, Y. N. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 6844-6849
11. Zilian, O., Saner, C., Hagedorn, L., Lee, H. Y., Sauberli, E., Suter, U., Sommer, L., and Aguet, M. (2001) Curr. Biol. 11, 494-501
12. Dho, S. E., French, M. B., Woods, S. A., and McGlade, C. J. (1999) J. Biol. Chem. 274, 33097-33104
13. Zhong, W. M., Jiang, M. M., Weinmaster, G., Jan, L. Y., and Jan, Y. N. (1997) Development 124, 1887-1897
14. Cayouette, M., Whitmore, A. V., Jeffery, G., and Raff, M. (2001) J. Neurosci. 21, 5643-5651
15. Wakamatsu, Y., Maynard, T. M., Jones, S. U., and Weston, J. A. (1999) Neuron 23, 71-81
16. Artavanis-Tsakonas, S., Rand, M. D., and Lake, R. J. (1999) Science 284, 770-776
17. Miele, L., and Osborne, B. (1999) J. Cell Phys. 181, 393-409
18. Dievart, A., Beaulieu, N., and Jolicooeur, P. (1999) Oncogene 18, 5973-5981
19. Ellisen, L. W., Bird, J., West, D. C., Soreng, A. L., Reynolds, T. C., Smith, S. D., and Sklar, J. (1991) Cell 66, 649-661
20. Joutel, A., and Tournier-Lasserve, F. (1998) Sem. Cell Dev. Biol. 9, 619-625
21. Kopan, R., and Turner, D. L. (1996) Curr. Opin. Neurobiol. 6, 594-601
22. Schroeter, E. H., Kisslinger, J. A., and Kopan, R. (1998) Nature 393, 382-386
23. Blaumueller, C. M., Qi, H., Zagouras, P., and Artivanis-Tsakonas, S. (1997) Cell 90, 281-291
24. Logeat, F., Bessia, C., Brou, C., LeBail, O., Jarriault, S., Seidaah, N. G., and Israel, A. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 8108-8112
25. Brou, C., Logeat, F., Gupta, N., Bessia, C., LeBail, O., Doedens, J. R., Cumano, A., Roux, P., Black, R. A., and Israel, A. (2000) Mol. Cell 5, 207-216
26. Berezovska, O., Jack, C., McLean, P., Aster, J. C., Hicks, C., Xia, W., Wolfe, M. S., Kimberly, W. T., Wienmaster, G., Selkoe, D. J., and Hyman, B. T. (2000) J. Neurochem. 75, 583-593
27. Kidd, S., Lieber, T., and Young, M. W. (1998) Genes Dev. 12, 3728-3740
28. Mumm, J. S., Schroeter, E. H., Saxena, M. T., Griesemer, A., Tian, X., Pan, D. J., Ray, W. J., and Kopan, R. (2000) Mol. Cell 5, 197-206
29. Struhl, G., and Adachi, A. (1998) Cell 93, 649-660
30. Lai, E. C. (2002) Curr. Biol. 12, R74-78
31. Hershko, A., and Ciechanover, A. (1998) Annu. Rev. Biochem. 67, 425-479
32. Joazeiro, C. A., and Weissman, A. M. (2000) Cell 102, 549-552
33. Tyers, M., and Willems, A. R. (1999) Science 284, 601, 603-604
34. Hicke, L. (1999) Trends Cell Biol. 9, 107-112
35. Rotin, D., Staub, O., and Haguenauer-Tsapis, R. (2000) J. Membr. Biol. 176, 1-17
36. Cornell, M., Evans, D. A., Mann, R., Fostier, M., Flasza, M., Monthatong, M., Artavanis-Tsakonas, S., and Baron, M. (1999) Genetics 152, 567-576
37. Qiu, L., Joazeiro, C., Fang, N., Wang, H. Y., Elly, C., Altman, Y., Fang, D., Hunter, T., and Liu, Y. C. (2000) J. Biol. Chem. 275, 35734-35737
38. Hubbard, E. J., Wu, G., Kitajewski, J., and Greenwald, I. (1997) Genes Dev. 11, 3182-3193
39. Gupta-Rossi, N., Le Bail, O., Gonen, H., Brou, C., Logeat, F., Six, E., Ciechanover, A., and Israel, A. (2001) J. Biol. Chem. 276, 34371-34378
40. Oberg, C., Li, J., Pauley, A., Wolf, E., Gurney, M., and Lendahl, U. (2001) J. Biol. Chem. 276, 35847-35853
41. Wu, G., Lyapina, S., Das, I., Li, J., Gurney, M., Pauley, A., Chui, I., Deshaies, R. J., and Kitajewski, J. (2001) Mol. Cell. Biol. 21, 7403-7415
42. Nie, J., McGill, M. A., Dermer, M., Dho, S. E., Wolting, C. D., and McGlade, C. J. (2002) EMBO J. 21, 93-102
43. Dho, S. E., Jacob, S., Wolting, C. D., French, M. B., Rohrschneider, L. R., and McGlade, C. J. (1998) J. Biol. Chem. 273, 9179-9187
44. Juven-Gershon, T., Shifman, O., Unger, T., Elkeles, A., Haupt, Y., and Oren, M. (1998) Mol. Cell. Biol. 18, 3974-3982
45. Susini, L., Passer, B. J., Amzallag-Elbaz, N., Juven-Gershon, T., Prieur, S., Privat, N., Tuynder, M., Gendron, M. C., Israel, A., Amson, R., Oren, M., and Telerman, A. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 15067-15072
46. Frise, E., Knoblich, J. A., Younger-Shepherd, S., Jan, L. Y., and Jan, Y. N. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 11925-11932
47. Berdnik, D., Torok, T., Gonzalez-Gaitan, M., and Knoblich, J. (2002) Dev. Cell 3, 221
48. Salcini, A. E., Confalonieri, S., Doria, M., Santolini, E., Tassi, E., Minenkova, O., Cesareni, G., Pelicci, P. G., and Difiore, P. P. (1997) Genes Dev. 11, 2239-2249
49. Santolini, E., Salcini, A. E., Kay, B. K., Yamabhai, M., and Di Fiore, P. P. (1999) Exp. Cell Res. 253, 186-209
50. Rand, M. D., Grimm, L. M., Artavanis-Tsakonas, S., Patriub, V., Blacklow, S. C., Sklar, J., and Aster, J. C. (2000) Mol. Cell. Biol. 20, 1825-1835
51. Sestan, N., Artavanis-Tsakonas, S., and Rakic, P. (1999) Science 286, 741-746
52. Schweisguth, F. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 11382-11386
53. Santolini, E., Puri, C., Salcini, A. E., Gagliani, M. C., Pelicci, P. G., Tacchetti, C., and Di Fiore, P. P. (2000) J. Cell Biol. 151, 1345-1352