메뉴 건너뛰기




Volumn 406, Issue 6794, 2000, Pages 369-375

Fringe is a glycosyltransferase that modifies Notch

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR; FUCOSE; GLYCOSYLTRANSFERASE; NOTCH RECEPTOR;

EID: 0001395691     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/35019000     Document Type: Article
Times cited : (743)

References (49)
  • 1
    • 0033617522 scopus 로고    scopus 로고
    • Notch signalling: Cell fate control and signal integration in development
    • Artavanis-Tsakonas, S., Rand, M. D. & Lake, R. J. Notch signalling: Cell fate control and signal integration in development. Science 284, 770-776 (1999).
    • (1999) Science , vol.284 , pp. 770-776
    • Artavanis-Tsakonas, S.1    Rand, M.D.2    Lake, R.J.3
  • 5
    • 0030845799 scopus 로고    scopus 로고
    • Serrate-mediated activation of Notch is specifically blocked by the product of the gene fringe in the dorsal compartment of the Drosophila wing imaginal disc
    • Fleming, R. J., Gu, Y. & Hukriede, N. A. Serrate-mediated activation of Notch is specifically blocked by the product of the gene fringe in the dorsal compartment of the Drosophila wing imaginal disc. Development 124, 2973-2981 (1997).
    • (1997) Development , vol.124 , pp. 2973-2981
    • Fleming, R.J.1    Gu, Y.2    Hukriede, N.A.3
  • 6
    • 0031713635 scopus 로고    scopus 로고
    • Interactions among Delta, Serrate and Fringe modulate Notch activity during Drosophila wing development
    • Klein, T. & Arias, A. M. Interactions among Delta, Serrate and Fringe modulate Notch activity during Drosophila wing development. Development 125, 2951-2962 (1998).
    • (1998) Development , vol.125 , pp. 2951-2962
    • Klein, T.1    Arias, A.M.2
  • 7
    • 0027945519 scopus 로고
    • Fringe, a boundary-specific signalling molecule, mediates interactions between dorsal and ventral cells during Drosophila wing development
    • Irvine, K. D. & Wieschaus, E. fringe, a boundary-specific signalling molecule, mediates interactions between dorsal and ventral cells during Drosophila wing development. Cell 79, 595-606 (1994).
    • (1994) Cell , vol.79 , pp. 595-606
    • Irvine, K.D.1    Wieschaus, E.2
  • 8
    • 0033523278 scopus 로고    scopus 로고
    • Fringe, Notch, and making developmental boundaries
    • Irvine, K. D. Fringe, Notch, and making developmental boundaries. Curr. Opin. Genet. Dev. 9, 434-441 (1999).
    • (1999) Curr. Opin. Genet. Dev. , vol.9 , pp. 434-441
    • Irvine, K.D.1
  • 9
    • 0030722165 scopus 로고    scopus 로고
    • Dorsal-ventral signalling in limb development
    • Irvine, K. D. & Vogt, T. F. Dorsal-ventral signalling in limb development. Curr. Opin. Cell Biol. 9, 867-876 (1997).
    • (1997) Curr. Opin. Cell Biol. , vol.9 , pp. 867-876
    • Irvine, K.D.1    Vogt, T.F.2
  • 10
    • 0030744231 scopus 로고    scopus 로고
    • A family of mammalian Fringe genes implicated in boundary determination and the Notch pathway
    • Johnston, S. H. et al. A family of mammalian Fringe genes implicated in boundary determination and the Notch pathway. Development 124, 2245-2254 (1997).
    • (1997) Development , vol.124 , pp. 2245-2254
    • Johnston, S.H.1
  • 11
    • 0030981168 scopus 로고    scopus 로고
    • Fringe boundaries coincide with Notch-dependent patterning centres in mammals and alter Notch-dependent development in Drosophila
    • Cohen, B. et al. Fringe boundaries coincide with Notch-dependent patterning centres in mammals and alter Notch-dependent development in Drosophila. Nature Genet. 16, 283-288 (1997).
    • (1997) Nature Genet. , vol.16 , pp. 283-288
    • Cohen, B.1
  • 12
    • 0031561502 scopus 로고    scopus 로고
    • Secreted fringe-like signaling molecules may be glycosyltransferases
    • Yuan, Y. P., Schultz, J., Mlodzik, M. & Bork, P. Secreted fringe-like signaling molecules may be glycosyltransferases. Cell 88, 9-11 (1997).
    • (1997) Cell , vol.88 , pp. 9-11
    • Yuan, Y.P.1    Schultz, J.2    Mlodzik, M.3    Bork, P.4
  • 13
    • 0034737738 scopus 로고    scopus 로고
    • Mammalian Notch1 is modified with two unusual forms of O-linked glycosylation found on Epidermal Growth Factor-like modules
    • Moloney, D. J. et al. Mammalian Notch1 is modified with two unusual forms of O-linked glycosylation found on Epidermal Growth Factor-like modules. J. Biol. Chem. 275, 9604-9611 (2000).
    • (2000) J. Biol. Chem. , vol.275 , pp. 9604-9611
    • Moloney, D.J.1
  • 14
    • 0027205366 scopus 로고
    • O-linked fucose and other post-translational modifications unique to EGF modules
    • Harris, R. J. & Spellman, M. W. O-linked fucose and other post-translational modifications unique to EGF modules. Glycobiology 3, 219-224 (1993).
    • (1993) Glycobiology , vol.3 , pp. 219-224
    • Harris, R.J.1    Spellman, M.W.2
  • 15
    • 0030853960 scopus 로고    scopus 로고
    • The O-linked fucose glycosylation pathway: Evidence for protein specific elongation of O-linked fucose in Chinese hamster ovary cells
    • Moloney, D. J., Lin, A. I. & Haltiwanger, R. S. The O-linked fucose glycosylation pathway: evidence for protein specific elongation of O-linked fucose in Chinese hamster ovary cells. J. Biol. Chem. 272, 19046-19050 (1997).
    • (1997) J. Biol. Chem. , vol.272 , pp. 19046-19050
    • Moloney, D.J.1    Lin, A.I.2    Haltiwanger, R.S.3
  • 16
    • 0010209342 scopus 로고
    • Chinese hamster ovary cells selected for resistance to the cytotoxicity of phytohemagglutinin are deficient in a UDP-N-acetylglucosamineglycoprotein N-acetylglucosaminyltransferase activity
    • Stanley, P., Narasimhan, S., Siminovitch, L. & Schachter, H. Chinese hamster ovary cells selected for resistance to the cytotoxicity of phytohemagglutinin are deficient in a UDP-N-acetylglucosamineglycoprotein N-acetylglucosaminyltransferase activity. Proc. Natl Acad. Sci. USA 72, 3323-3327 (1975).
    • (1975) Proc. Natl Acad. Sci. USA , vol.72 , pp. 3323-3327
    • Stanley, P.1    Narasimhan, S.2    Siminovitch, L.3    Schachter, H.4
  • 17
    • 0017944196 scopus 로고
    • Specific changes in the oligosaccharide moieties of VSV grown in different lectin-resistant CHO cells
    • Robertson, M. A., Etchíson, J. R., Robertson, J. S., Summers, D. F. & Stanley, P. Specific changes in the oligosaccharide moieties of VSV grown in different lectin-resistant CHO cells. Cell 13, 515-526 (1978).
    • (1978) Cell , vol.13 , pp. 515-526
    • Robertson, M.A.1    Etchíson, J.R.2    Robertson, J.S.3    Summers, D.F.4    Stanley, P.5
  • 18
    • 0032805976 scopus 로고    scopus 로고
    • The O-linked fucose glycosylation pathway: Identification and characterization of a UDP-glucose: O-fucose β1,3-glucosyltransferase
    • Moloney, D. J. & Haltiwanger, R. S. The O-linked fucose glycosylation pathway: Identification and characterization of a UDP-glucose: O-fucose β1,3-glucosyltransferase. Glycobiology 9, 679-687 (1999).
    • (1999) Glycobiology , vol.9 , pp. 679-687
    • Moloney, D.J.1    Haltiwanger, R.S.2
  • 19
    • 0033153159 scopus 로고    scopus 로고
    • The effect of O-fucosylation on the first EGF-like domain from human blood coagulation Factor VII
    • Kao, Y. -H. et al. The effect of O-fucosylation on the first EGF-like domain from human blood coagulation Factor VII. Biochemistry 38, 7097-7110 (1999).
    • (1999) Biochemistry , vol.38 , pp. 7097-7110
    • Kao, Y.H.1
  • 20
    • 0019485676 scopus 로고
    • Glycosyltransferases and their use in assessing oligosaccharide structure and structure-function relationships
    • Beyer, T. A., Sadler, J. E., Rearick, J. I., Paulson, J. C. & Hill, R. L. Glycosyltransferases and their use in assessing oligosaccharide structure and structure-function relationships. Adv. Enzymol 52, 23-175 (1981).
    • (1981) Adv. Enzymol , vol.52 , pp. 23-175
    • Beyer, T.A.1    Sadler, J.E.2    Rearick, J.I.3    Paulson, J.C.4    Hill, R.L.5
  • 21
    • 0028950732 scopus 로고
    • Jagged: A mammalian ligand that activates Notch1
    • Lindsell, C. E., Shawber, C. J., Boulter, J. & Weinmaster, G. Jagged: A mammalian ligand that activates Notch1. Cell 80, 909-917 (1995).
    • (1995) Cell , vol.80 , pp. 909-917
    • Lindsell, C.E.1    Shawber, C.J.2    Boulter, J.3    Weinmaster, G.4
  • 22
    • 0343630391 scopus 로고    scopus 로고
    • Fringe differentially modulates Jagged1 and Delta1 signalling through Notch1 and Notch2 receptors in mammalian cells
    • in the press
    • Hicks, C., Johnston, S. H., DiSibio, G., Collazo, A., Vogt, T. F. & Weinmaster, G. Fringe differentially modulates Jagged1 and Delta1 signalling through Notch1 and Notch2 receptors in mammalian cells. Nature Cell Biol. (in the press).
    • Nature Cell Biol.
    • Hicks, C.1    Johnston, S.H.2    DiSibio, G.3    Collazo, A.4    Vogt, T.F.5    Weinmaster, G.6
  • 23
    • 0030063909 scopus 로고    scopus 로고
    • Truncated mammalian Notch1 activates CBFI/RBPJk-repressed genes by a mechanism resembling that of Epstein-Barr virus EBNA2
    • Hsich, J. J. Henkel, T., Salmon, P., Robey, E., Peterson, M. G. & Hayward, S. D. Truncated mammalian Notch1 activates CBFI/RBPJk-repressed genes by a mechanism resembling that of Epstein-Barr virus EBNA2. Mol. Cell. Biol. 16, 952-959 (1996).
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 952-959
    • Hsich, J.J.1    Henkel, T.2    Salmon, P.3    Robey, E.4    Peterson, M.G.5    Hayward, S.D.6
  • 24
    • 0022652983 scopus 로고
    • Lectin-resistant CHO cells: Selection of four new pea lectin-resistant phenotypes
    • Ripka, J. & Stanley, P. Lectin-resistant CHO cells: Selection of four new pea lectin-resistant phenotypes. Som. Cell. Mol. Gen. 12, 51-62 (1986).
    • (1986) Som. Cell. Mol. Gen. , vol.12 , pp. 51-62
    • Ripka, J.1    Stanley, P.2
  • 25
    • 0022477288 scopus 로고
    • Two Chinese hamster ovary glycosylation mutants affected in the conversion of GDP-mannose to GDP-fucose
    • Ripka, J., Adamany, A. & Stanley, P. Two Chinese hamster ovary glycosylation mutants affected in the conversion of GDP-mannose to GDP-fucose. Arch. Biochem. Biophys. 249, 533-545 (1986).
    • (1986) Arch. Biochem. Biophys. , vol.249 , pp. 533-545
    • Ripka, J.1    Adamany, A.2    Stanley, P.3
  • 26
    • 0032478832 scopus 로고    scopus 로고
    • Molecular cloning of human GDP-mannose 4,6-dehydratase and reconsititution of GDP-fucose biosynthesis in vitro
    • Sullivan, F. X. et al. Molecular cloning of human GDP-mannose 4,6-dehydratase and reconsititution of GDP-fucose biosynthesis in vitro. J. Biol. Chem. 273, 8193-8202 (1998).
    • (1998) J. Biol. Chem. , vol.273 , pp. 8193-8202
    • Sullivan, F.X.1
  • 27
    • 0032486278 scopus 로고    scopus 로고
    • Molecular cloning and expression of GDP-D-mannose-4,6-dehydratase, a key enzyme for fucose metabolism defective in Lec13 cells
    • Ohyama, C. et al. Molecular cloning and expression of GDP-D-mannose-4,6-dehydratase, a key enzyme for fucose metabolism defective in Lec13 cells. J. Biol. Chem. 273, 14582-14587 (1998).
    • (1998) J. Biol. Chem. , vol.273 , pp. 14582-14587
    • Ohyama, C.1
  • 28
    • 0032493440 scopus 로고    scopus 로고
    • Activity of the yeast MNN1 α-1,3-mannosyltransferase requires a motif conserved in many other families of glycosyltransferases
    • Wiggins, C. A. R. & Munro, S. Activity of the yeast MNN1 α-1,3-mannosyltransferase requires a motif conserved in many other families of glycosyltransferases. Proc. Natl Acad. Sci. USA 95, 7945-7950 (1998).
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 7945-7950
    • Wiggins, C.A.R.1    Munro, S.2
  • 29
    • 0032766699 scopus 로고    scopus 로고
    • Role of a conserved acidic cluster in bovine β1,4 galactosyltransferase-1 probed by mutagenesis of a bacterially expressed recombinant enzyme
    • Zhang, Y., Malinovskii, V. A., Fiedler, T. J. & Brew, K. Role of a conserved acidic cluster in bovine β1,4 galactosyltransferase-1 probed by mutagenesis of a bacterially expressed recombinant enzyme. Glycobiology 9, 815-822 (1999).
    • (1999) Glycobiology , vol.9 , pp. 815-822
    • Zhang, Y.1    Malinovskii, V.A.2    Fiedler, T.J.3    Brew, K.4
  • 30
    • 0029093437 scopus 로고
    • Cell recognition, signal induction, and symmetrical gene activation at the dorsal-ventral boundary of the developing Drosophila wing
    • Kim, J., Irvine, K. D. & Carroll, S. B. Cell recognition, signal induction, and symmetrical gene activation at the dorsal-ventral boundary of the developing Drosophila wing. Cell 82, 795-802 (1995).
    • (1995) Cell , vol.82 , pp. 795-802
    • Kim, J.1    Irvine, K.D.2    Carroll, S.B.3
  • 31
    • 0027160708 scopus 로고
    • Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
    • Brand, A. H. & Perrimon, N. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118, 401-415 (1993).
    • (1993) Development , vol.118 , pp. 401-415
    • Brand, A.H.1    Perrimon, N.2
  • 32
    • 0034636541 scopus 로고    scopus 로고
    • Fringe forms a complex with Notch
    • Ju, B. -G. et al. Fringe forms a complex with Notch. Nature 405, 191-195 (2000).
    • (2000) Nature , vol.405 , pp. 191-195
    • Ju, B.G.1
  • 33
    • 0026086474 scopus 로고
    • Specific EGF repeats of Notch mediate interactions with Delta and Serrate: Implications for Notch as a multifunctional receptor
    • Rebay, J. et al. Specific EGF repeats of Notch mediate interactions with Delta and Serrate: Implications for Notch as a multifunctional receptor. Cell 67, 687-699 (1991).
    • (1991) Cell , vol.67 , pp. 687-699
    • Rebay, J.1
  • 34
    • 0032705926 scopus 로고    scopus 로고
    • Ligand-receptor interactions and trans-endocytosis of Delta, Serrate and Notch: Members of the Notch signaling pathway in Drosophila
    • Klueg, K. M. & Muskavitch, M. A. Ligand-receptor interactions and trans-endocytosis of Delta, Serrate and Notch: members of the Notch signaling pathway in Drosophila. J. Cell Sci. 112, 3289-3297 (1999).
    • (1999) J. Cell Sci. , vol.112 , pp. 3289-3297
    • Klueg, K.M.1    Muskavitch, M.A.2
  • 35
    • 0023661270 scopus 로고
    • Mutations altering the structure of Epidermal Growth Factor-like coding sequences of the Drosophila notch locus
    • Kelley, M. R., Kidd, S., Deutsch, W. A. & Young, M. W. Mutations altering the structure of Epidermal Growth Factor-like coding sequences of the Drosophila notch locus. Cell 51, 539-548 (1987).
    • (1987) Cell , vol.51 , pp. 539-548
    • Kelley, M.R.1    Kidd, S.2    Deutsch, W.A.3    Young, M.W.4
  • 36
    • 0028244967 scopus 로고
    • Roles of the Notch gene in Drosophila wing morphogenesis
    • De Celis, J. F. & Garcia-Bellido, A. Roles of the Notch gene in Drosophila wing morphogenesis. Mech. Dev. 46, 109-122 (1994).
    • (1994) Mech. Dev. , vol.46 , pp. 109-122
    • De Celis, J.F.1    Garcia-Bellido, A.2
  • 37
    • 0034038237 scopus 로고    scopus 로고
    • The Abruplex domain of Notch regulates negative interactions between Notch, its ligands and Fringe
    • De Celis, J. F. & Bray, S. J. The Abruplex domain of Notch regulates negative interactions between Notch, its ligands and Fringe. Development 127, 1291-1302 (2000).
    • (2000) Development , vol.127 , pp. 1291-1302
    • De Celis, J.F.1    Bray, S.J.2
  • 38
    • 0032037786 scopus 로고    scopus 로고
    • Diseases of abnormal protein glycosylation: An emerging area
    • Kornfeld, S. Diseases of abnormal protein glycosylation: An emerging area. J. Clin. Invest. 101, 1293-1295 (1998).
    • (1998) J. Clin. Invest. , vol.101 , pp. 1293-1295
    • Kornfeld, S.1
  • 39
    • 0040293459 scopus 로고    scopus 로고
    • A new type of carbohydrate-deficient glycoprotein syndrome due to a decreased import of GDP-fucose into the Golgi
    • Lubke, T., Marquardt, T., von Figura, K. & Korner, C. A new type of carbohydrate-deficient glycoprotein syndrome due to a decreased import of GDP-fucose into the Golgi. J. Biol. Chem. 274, 25986-25989 (1999).
    • (1999) J. Biol. Chem. , vol.274 , pp. 25986-25989
    • Lubke, T.1    Marquardt, T.2    Von Figura, K.3    Korner, C.4
  • 40
    • 0034643323 scopus 로고    scopus 로고
    • Specificities of heparan sulphate proteoglycans in developmental processes
    • Perrimon, N. & Bernfield, M. Specificities of heparan sulphate proteoglycans in developmental processes. Nature 404, 725-728 (2000).
    • (2000) Nature , vol.404 , pp. 725-728
    • Perrimon, N.1    Bernfield, M.2
  • 42
    • 0029997061 scopus 로고    scopus 로고
    • Constitutively active human Notch1 binds to the transcription factor CBF1 and stimulates transcription through a promoter containing a CBF1-responsive element
    • Lu, F. M. & Lux, S. E. Constitutively active human Notch1 binds to the transcription factor CBF1 and stimulates transcription through a promoter containing a CBF1-responsive element. Proc. Natl Acad. Sci. USA 93, 5663-5667 (1996).
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 5663-5667
    • Lu, F.M.1    Lux, S.E.2
  • 43
    • 0029086140 scopus 로고
    • Complementary gradients in expression and binding of Elf-1 and Mek-4 in development of the topographic retinotectal projection map
    • Cheng, H. J., Nakamoto, M., Bergemann, A. D. & Flanagan, J. G. Complementary gradients in expression and binding of Elf-1 and Mek-4 in development of the topographic retinotectal projection map. Cell 82, 371-381 (1995).
    • (1995) Cell , vol.82 , pp. 371-381
    • Cheng, H.J.1    Nakamoto, M.2    Bergemann, A.D.3    Flanagan, J.G.4
  • 45
    • 0027306001 scopus 로고
    • Specific truncations of Drosophila Notch define dominant activated and dominant negative forms of the receptor
    • Rebay, I., Fehon, R. G. & Artavanis-Tsakonas, S. Specific truncations of Drosophila Notch define dominant activated and dominant negative forms of the receptor. Cell 74, 319-329 (1993).
    • (1993) Cell , vol.74 , pp. 319-329
    • Rebay, I.1    Fehon, R.G.2    Artavanis-Tsakonas, S.3
  • 46
    • 0031711820 scopus 로고    scopus 로고
    • Transporters of nucleotide sugars, ATP, and nucleotide sulfate in the endoplasmic reticulum and Golgi apparatus
    • Hirschberg, C. B., Robbins, P. W. & Abeijon, C. Transporters of nucleotide sugars, ATP, and nucleotide sulfate in the endoplasmic reticulum and Golgi apparatus. Annu. Rev. Biochem. 67, 49-69 (1998).
    • (1998) Annu. Rev. Biochem. , vol.67 , pp. 49-69
    • Hirschberg, C.B.1    Robbins, P.W.2    Abeijon, C.3
  • 47
    • 0033868818 scopus 로고    scopus 로고
    • A novel proteolytic cleavage involved in Notch signalling: The role of the disintegrinmetalloprotease TACE
    • Brou, C. et al. A novel proteolytic cleavage involved in Notch signalling: The role of the disintegrinmetalloprotease TACE, Mol. Cell 5, 207-216 (2000).
    • (2000) Mol. Cell , vol.5 , pp. 207-216
    • Brou, C.1
  • 48
    • 0033867521 scopus 로고    scopus 로고
    • A ligand-induced extracellular cleavage regulates γ-secretase-like proteolytic activation of Notch1
    • Mumm, J. S. et al. A ligand-induced extracellular cleavage regulates γ-secretase-like proteolytic activation of Notch1. Mol. Cell 5, 197-206 (2000).
    • (2000) Mol. Cell , vol.5 , pp. 197-206
    • Mumm, J.S.1
  • 49
    • 0033535504 scopus 로고    scopus 로고
    • A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular fragment
    • De Strooper, B. et al. A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular fragment. Nature 398, 518-522 (1999).
    • (1999) Nature , vol.398 , pp. 518-522
    • De Strooper, B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.