Notch and Mef2 synergize to promote proliferation and metastasis through JNK signal activation in Drosophila

EMBO Journal

Volumn 31, Issue 13, 2012, Pages 2895-2907

  Pallavi, S K ^a   Ho, Diana M ^a   Hicks, Chindo ^b   Miele, Lucio ^b   Artavanis Tsakonas, Spyros ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MISSISSIPPI MEDICAL CENTER   (United States)

Author keywords

JNK; Mef2; metastasis; Notch; proliferation

Indexed keywords

EIGER PROTEIN; INTERSTITIAL COLLAGENASE; MYOCYTE ENHANCER FACTOR 2; NOTCH RECEPTOR; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL; CELL DIFFERENTIATION; CELL INVASION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE RELEASE; DROSOPHILA; GENE EXPRESSION; HUMAN; HUMAN CELL; MALE; METASTASIS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION;

ANIMALS; BREAST NEOPLASMS; CELL PROLIFERATION; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; FEMALE; GENE EXPRESSION PROFILING; HUMANS; MALE; MAP KINASE SIGNALING SYSTEM; MATRIX METALLOPROTEINASE 1; MEMBRANE PROTEINS; MYOGENIC REGULATORY FACTORS; NEOPLASM METASTASIS; RECEPTORS, NOTCH; UP-REGULATION;

EID: 84863846777     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2012.129     Document Type: Article

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