-
1
-
-
0033617522
-
Notch signaling: Cell fate control and signal integration in development
-
Artavanis-Tsakonas, S., M. D. Rand, and R. J. Lake. 1999. Notch signaling: Cell fate control and signal integration in development. Science 284:770-776.
-
(1999)
Science
, vol.284
, pp. 770-776
-
-
Artavanis-Tsakonas, S.1
Rand, M.D.2
Lake, R.J.3
-
2
-
-
0028674212
-
Functional analysis of the TAN-1 gene, a human homolog of Drosophila notch
-
Aster, J., W. Pear, R. Hasserjian, H. Erba, F. Davi, B. Luo, M. Scott, D. Baltimore, and J. Sklar. 1994. Functional analysis of the TAN-1 gene, a human homolog of Drosophila notch. Cold Spring Harbor Symp. Quant. Biol. 59:125-136.
-
(1994)
Cold Spring Harbor Symp. Quant. Biol.
, vol.59
, pp. 125-136
-
-
Aster, J.1
Pear, W.2
Hasserjian, R.3
Erba, H.4
Davi, F.5
Luo, B.6
Scott, M.7
Baltimore, D.8
Sklar, J.9
-
3
-
-
0030945447
-
Oncogenic forms of NOTCH1 lacking either the primary binding site for RBP-Jκ or nuclear localization sequences retain the ability to associate with RBP-Jκ and activate transcription
-
Aster, J. C., E. S. Robertson, R. P. Hasserjian, J. R. Turner, E. Kieff, and J. Sklar. 1997. Oncogenic forms of NOTCH1 lacking either the primary binding site for RBP-Jκ or nuclear localization sequences retain the ability to associate with RBP-Jκ and activate transcription. J. Biol. Chem. 272:11336-11343.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 11336-11343
-
-
Aster, J.C.1
Robertson, E.S.2
Hasserjian, R.P.3
Turner, J.R.4
Kieff, E.5
Sklar, J.6
-
4
-
-
0033796150
-
Essential roles for ankyrin repeat and transactivation domains in induction of T-cell leukemia by Notch1
-
Aster, J. C., L. Xu, F. G. Karnell, V. Patriub, J. C. Pui, and W. S. Pear. 2000. Essential roles for ankyrin repeat and transactivation domains in induction of T-cell leukemia by Notch1. Mol. Cell. Biol. 20:7505-7515.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 7505-7515
-
-
Aster, J.C.1
Xu, L.2
Karnell, F.G.3
Patriub, V.4
Pui, J.C.5
Pear, W.S.6
-
5
-
-
0033944273
-
Aspartate mutations in presenilin and gamma-secretase inhibitors both impair notch1 proteolysis and nuclear translocation with relative preservation of notch1 signaling
-
Berezovska, O., C. Jack, P. McLean, J. C. Aster, C. Hicks, W. Xia, M. S. Wolfe, W. T. Kimberly, G. Weinmaster, D. J. Selkoe, and B. T. Hyman. 2000. Aspartate mutations in presenilin and gamma-secretase inhibitors both impair notch1 proteolysis and nuclear translocation with relative preservation of notch1 signaling. J. Neurochem. 75:583-593.
-
(2000)
J. Neurochem.
, vol.75
, pp. 583-593
-
-
Berezovska, O.1
Jack, C.2
McLean, P.3
Aster, J.C.4
Hicks, C.5
Xia, W.6
Wolfe, M.S.7
Kimberly, W.T.8
Weinmaster, G.9
Selkoe, D.J.10
Hyman, B.T.11
-
6
-
-
0031030361
-
Germ-line tumor formation caused by activation of glp-1, a Caenorhabditis elegans member of the Notch family of receptors
-
Berry, L. W., B. Westlund, and T. Schedl. 1997. Germ-line tumor formation caused by activation of glp-1, a Caenorhabditis elegans member of the Notch family of receptors. Development 124:925-936.
-
(1997)
Development
, vol.124
, pp. 925-936
-
-
Berry, L.W.1
Westlund, B.2
Schedl, T.3
-
7
-
-
0033868818
-
A novel proteolytic cleavage involved in Notch signaling: The role of the disintegrin-metalloprotease TACE
-
Brou, C., F. Logeat, N. Gupta, C. Bessia, O. LeBail, J. R. Doedens, A. Cumano, P. Roux, R. A. Black, and A. Israel. 2000. A novel proteolytic cleavage involved in Notch signaling: The role of the disintegrin-metalloprotease TACE. Mol. Cell 5:207-216.
-
(2000)
Mol. Cell
, vol.5
, pp. 207-216
-
-
Brou, C.1
Logeat, F.2
Gupta, N.3
Bessia, C.4
LeBail, O.5
Doedens, J.R.6
Cumano, A.7
Roux, P.8
Black, R.A.9
Israel, A.10
-
8
-
-
0035862738
-
Ligand-induced signaling in the absence of furin processing of Notch1
-
Bush, G., G. diSibio, A. Miyamoto, J. B. Denault, R. Leduc, and G. Weinmaster. 2001. Ligand-induced signaling in the absence of furin processing of Notch1. Dev. Biol. 229:494-502.
-
(2001)
Dev. Biol.
, vol.229
, pp. 494-502
-
-
Bush, G.1
DiSibio, G.2
Miyamoto, A.3
Denault, J.B.4
Leduc, R.5
Weinmaster, G.6
-
9
-
-
0030820930
-
Neoplastic transformation by truncated alleles of human NOTCH1/TAN1 and NOTCH2
-
Capobianco, A. J., P. Zagouras, C. M. Blaumueller, S. Artavanis-Tsakonas, and J. M. Bishop. 1997. Neoplastic transformation by truncated alleles of human NOTCH1/TAN1 and NOTCH2. Mol. Cell. Biol. 17:6265-6273.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 6265-6273
-
-
Capobianco, A.J.1
Zagouras, P.2
Blaumueller, C.M.3
Artavanis-Tsakonas, S.4
Bishop, J.M.5
-
10
-
-
0032904239
-
Notch1-induced delay of human hematopoietic progenitor cell differentiation is associated with altered cell cycle kinetics
-
Carlesso, N., J. C. Aster, J. Sklar, and D. T. Scadden. 1999. Notch1-induced delay of human hematopoietic progenitor cell differentiation is associated with altered cell cycle kinetics. Blood 93:838-848.
-
(1999)
Blood
, vol.93
, pp. 838-848
-
-
Carlesso, N.1
Aster, J.C.2
Sklar, J.3
Scadden, D.T.4
-
11
-
-
0034038237
-
The Abruptex domain of Notch regulates negative interactions between Notch, its ligands and Fringe
-
De Celis, J. F., and S. J. Bray. 2000. The Abruptex domain of Notch regulates negative interactions between Notch, its ligands and Fringe. Development 127:1291-1302.
-
(2000)
Development
, vol.127
, pp. 1291-1302
-
-
De Celis, J.F.1
Bray, S.J.2
-
12
-
-
0032442040
-
Correlating notch signaling with thymocyte maturation
-
Deftos, M. L., Y. W. He, E. W. Ojala, and M. J. Bevan. 1998. Correlating notch signaling with thymocyte maturation. Immunity 9:777-786.
-
(1998)
Immunity
, vol.9
, pp. 777-786
-
-
Deftos, M.L.1
He, Y.W.2
Ojala, E.W.3
Bevan, M.J.4
-
13
-
-
0033535504
-
A presenilin-1-dependent-secretase-like protease mediates release of Notch intracellular domain
-
De Strooper, B., W. Annaert, P. Cupers, P. Saftig, K. Craessaerts, J. S. Mumm, E. H. Schroeter, V. Schruvers, M. S. Wolfe, W. J. Ray, A. Goate, and R. Kopan. 1999. A presenilin-1-dependent-secretase-like protease mediates release of Notch intracellular domain. Nature 398:518-522.
-
(1999)
Nature
, vol.398
, pp. 518-522
-
-
De Strooper, B.1
Annaert, W.2
Cupers, P.3
Saftig, P.4
Craessaerts, K.5
Mumm, J.S.6
Schroeter, E.H.7
Schruvers, V.8
Wolfe, M.S.9
Ray, W.J.10
Goate, A.11
Kopan, R.12
-
14
-
-
0035163347
-
Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain
-
Dovey, H. F., V. John, J. P. Anderson, L. Z. Chen, P. de Saint Andrieu, L. Y. Fang, S. B. Freedman, B. Folmer, E. Goldbach, E. J. Holsztynska, K. L. Hu, K. L. Johnson-Wood, S. L. Kennedy, D. Kholodenko, J. E. Knops, L. H. Latimer, M. Lee, Z. Liao, I. M. Lieberburg, R. N. Motter, L. C. Mutter, J. Nietz, K. P. Quinn, K. L. Sacchi, P. A. Seubert, G. M. Shopp, E. D. Thorsett, J. S. Tung, J. Wu, S. Yang, C. T. Yin, D. B. Schenk, P. C. May, L. D. Altstiel, M. H. Bender, L. N. Boggs, T. C. Britton, J. C. Clemens, D. L. Czilli, D. K. Dieckman-McGinty, J. J. Droste, K. S. Fuson, B. D. Gitter, P. A. Hyslop, E. M. Johnstone, W. Y. Li, S. P. Little, T. E. Mabry, F. D. Miller, and J. E. Audia. 2001. Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain. J. Neurochem. 76:173-181.
-
(2001)
J. Neurochem.
, vol.76
, pp. 173-181
-
-
Dovey, H.F.1
John, V.2
Anderson, J.P.3
Chen, L.Z.4
De Saint Andrieu, P.5
Fang, L.Y.6
Freedman, S.B.7
Folmer, B.8
Goldbach, E.9
Holsztynska, E.J.10
Hu, K.L.11
Johnson-Wood, K.L.12
Kennedy, S.L.13
Kholodenko, D.14
Knops, J.E.15
Latimer, L.H.16
Lee, M.17
Liao, Z.18
Lieberburg, I.M.19
Motter, R.N.20
Mutter, L.C.21
Nietz, J.22
Quinn, K.P.23
Sacchi, K.L.24
Seubert, P.A.25
Shopp, G.M.26
Thorsett, E.D.27
Tung, J.S.28
Wu, J.29
Yang, S.30
Yin, C.T.31
Schenk, D.B.32
May, P.C.33
Altstiel, L.D.34
Bender, M.H.35
Boggs, L.N.36
Britton, T.C.37
Clemens, J.C.38
Czilli, D.L.39
Dieckman-McGinty, D.K.40
Droste, J.J.41
Fuson, K.S.42
Gitter, B.D.43
Hyslop, P.A.44
Johnstone, E.M.45
Li, W.Y.46
Little, S.P.47
Mabry, T.E.48
Miller, F.D.49
Audia, J.E.50
more..
-
15
-
-
0034608814
-
SEL-8, a nuclear protein required for LIN-12 and GLP-1 signaling in Caenorhabditis elegans
-
Doyle, T. G., C. Wen, and I. Greenwald. 2000. SEL-8, a nuclear protein required for LIN-12 and GLP-1 signaling in Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA 97:7877-7881.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 7877-7881
-
-
Doyle, T.G.1
Wen, C.2
Greenwald, I.3
-
16
-
-
0025856717
-
TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms
-
Ellisen, L. W., J. Bird, D. C. West, A. L. Soreng, T. C. Reynolds, S. D. Smith, and J. Sklar. 1991. TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms. Cell 66:649-661.
-
(1991)
Cell
, vol.66
, pp. 649-661
-
-
Ellisen, L.W.1
Bird, J.2
West, D.C.3
Soreng, A.L.4
Reynolds, T.C.5
Smith, S.D.6
Sklar, J.7
-
17
-
-
0037022644
-
Activity-dependent isolation of the presenilingamma-secretase complex reveals nicastrin and a gamma substrate
-
Esler, W. P., W. T. Kimberly, B. L. Ostaszewski, W. Ye, T. S. Diehl, D. J. Selkoe, and M. S. Wolfe. 2002. Activity-dependent isolation of the presenilingamma-secretase complex reveals nicastrin and a gamma substrate. Proc. Natl. Acad. Sci. USA 99:2720-2725.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 2720-2725
-
-
Esler, W.P.1
Kimberly, W.T.2
Ostaszewski, B.L.3
Ye, W.4
Diehl, T.S.5
Selkoe, D.J.6
Wolfe, M.S.7
-
18
-
-
0032751132
-
SEL-5, a serine/threonine kinase that facilitates lin-12 activity in Caenorhabditis elegans
-
Fares, H., and I. Greenwald. 1999. SEL-5, a serine/threonine kinase that facilitates lin-12 activity in Caenorhabditis elegans. Genetics 153:1641-1654.
-
(1999)
Genetics
, vol.153
, pp. 1641-1654
-
-
Fares, H.1
Greenwald, I.2
-
19
-
-
0027378244
-
An activated Notch receptor blocks cell-fate commitment in the developing Drosophila eye
-
Fortini, M. E., I. Rebay, L. A. Caron, and S. Artavanis-Tsakonas. 1993. An activated Notch receptor blocks cell-fate commitment in the developing Drosophila eye. Nature 365:555-557.
-
(1993)
Nature
, vol.365
, pp. 555-557
-
-
Fortini, M.E.1
Rebay, I.2
Caron, L.A.3
Artavanis-Tsakonas, S.4
-
20
-
-
0036606776
-
Mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complex
-
Fryer, C. J., E. Lamar, I. Turbachova, C. Kintner, and K. A. Jones. 2002. Mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complex. Genes Dev. 16:1397-1411.
-
(2002)
Genes Dev.
, vol.16
, pp. 1397-1411
-
-
Fryer, C.J.1
Lamar, E.2
Turbachova, I.3
Kintner, C.4
Jones, K.A.5
-
21
-
-
0031835079
-
Cell proliferation control by Notch signaling in Drosophila development
-
Go, M. J., D. S. Eastman, and S. Artavanis-Tsakonas. 1998. Cell proliferation control by Notch signaling in Drosophila development. Development 125:2031-2040.
-
(1998)
Development
, vol.125
, pp. 2031-2040
-
-
Go, M.J.1
Eastman, D.S.2
Artavanis-Tsakonas, S.3
-
22
-
-
0025316499
-
Analysis of gain-of-function mutations of the lin-12 gene of Caenorhabditis elegans
-
Greenwald, I., and G. Seydoux. 1990. Analysis of gain-of-function mutations of the lin-12 gene of Caenorhabditis elegans. Nature 346:197-199.
-
(1990)
Nature
, vol.346
, pp. 197-199
-
-
Greenwald, I.1
Seydoux, G.2
-
23
-
-
0028133036
-
Mediation of Epstein-Barr virus EBNA2 transactivation by recombination signal-binding protein Jκ
-
Henkel, T., P. D. Ling, S. D. Hayward, and M. G. Peterson. 1994. Mediation of Epstein-Barr virus EBNA2 transactivation by recombination signal-binding protein Jκ. Science 265:92-95.
-
(1994)
Science
, vol.265
, pp. 92-95
-
-
Henkel, T.1
Ling, P.D.2
Hayward, S.D.3
Peterson, M.G.4
-
24
-
-
0030063909
-
Truncated mammalian Notch1 activates CBF1/RBPJκ-repressed genes by a mechanism resembling that of Epstein-Barr virus EBNA2
-
Hsieh, J. J., T. Henkel, P. Salmon, E. Robey, M. G. Peterson, and S. D. Hayward. 1996. Truncated mammalian Notch1 activates CBF1/RBPJκ-repressed genes by a mechanism resembling that of Epstein-Barr virus EBNA2. Mol. Cell. Biol. 16:952-959.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 952-959
-
-
Hsieh, J.J.1
Henkel, T.2
Salmon, P.3
Robey, E.4
Peterson, M.G.5
Hayward, S.D.6
-
25
-
-
0034702303
-
Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1
-
Huppert, S. S., A. Le, E. H. Schroeter, J. S. Mumm, M. T. Saxena, L. A. Milner, and R. Kopan. 2000. Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1. Nature 405:966-970.
-
(2000)
Nature
, vol.405
, pp. 966-970
-
-
Huppert, S.S.1
Le, A.2
Schroeter, E.H.3
Mumm, J.S.4
Saxena, M.T.5
Milner, L.A.6
Kopan, R.7
-
26
-
-
17744363445
-
Notch1 regulates maturation of CD4+ and CD8+ thymocytes by modulating TCR signal strength
-
Izon, D. J., J. A. Punt, L. Xu, F. G. Karnell, D. Allman, P. S. Myung, N. J. Boerth, J. C. Pui, G. A. Koretzky, and W. S. Pear. 2001. Notch1 regulates maturation of CD4+ and CD8+ thymocytes by modulating TCR signal strength. Immunity 14:253-264.
-
(2001)
Immunity
, vol.14
, pp. 253-264
-
-
Izon, D.J.1
Punt, J.A.2
Xu, L.3
Karnell, F.G.4
Allman, D.5
Myung, P.S.6
Boerth, N.J.7
Pui, J.C.8
Koretzky, G.A.9
Pear, W.S.10
-
27
-
-
0034024625
-
Neoplastic transformation by Notch requires nuclear localization
-
Jeffries, S., and A. J. Capobianco. 2000. Neoplastic transformation by Notch requires nuclear localization. Mol. Cell. Biol. 20:3928-3941.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 3928-3941
-
-
Jeffries, S.1
Capobianco, A.J.2
-
28
-
-
0036096912
-
Characterization of a high-molecular-weight Notch complex in the nucleus of Notch(ic)-transformed RKE cells and in a human T-cell leukemia cell line
-
Jeffries, S., D. J. Robbins, and A. J. Capobianco. 2002. Characterization of a high-molecular-weight Notch complex in the nucleus of Notch(ic)-transformed RKE cells and in a human T-cell leukemia cell line. Mol. Cell. Biol. 22:3927-3941.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 3927-3941
-
-
Jeffries, S.1
Robbins, D.J.2
Capobianco, A.J.3
-
29
-
-
0033556251
-
Protective effects of notch-1 on TCR-induced apoptosis
-
Jehn, B. M., W. Bielke, W. S. Pear, and B. A. Osborne. 1999. Protective effects of notch-1 on TCR-induced apoptosis. J Immunol. 162:635-638.
-
(1999)
J Immunol.
, vol.162
, pp. 635-638
-
-
Jehn, B.M.1
Bielke, W.2
Pear, W.S.3
Osborne, B.A.4
-
30
-
-
0036566557
-
Activated Notch1 signaling promotes tumor cell proliferation and survival in Hodgkin and anaplastic large cell lymphoma
-
Jundt, F., I. Anagnostopoulos, R. Forster, S. Mathas, H. Stein, and B. Dorken. 2002. Activated Notch1 signaling promotes tumor cell proliferation and survival in Hodgkin and anaplastic large cell lymphoma. Blood 99:3398-3403.
-
(2002)
Blood
, vol.99
, pp. 3398-3403
-
-
Jundt, F.1
Anagnostopoulos, I.2
Forster, R.3
Mathas, S.4
Stein, H.5
Dorken, B.6
-
31
-
-
0030782174
-
Involvement of RBP-J in biological functions of mouse Notch1 and its derivatives
-
Kato, H., Y. Taniguchi, H. Kurooka, S. Minoguchi, T. Sakai, S. Nomura-Okazaki, K. Tamura, and T. Honjo. 1997. Involvement of RBP-J in biological functions of mouse Notch1 and its derivatives. Development 124:4133-4141.
-
(1997)
Development
, vol.124
, pp. 4133-4141
-
-
Kato, H.1
Taniguchi, Y.2
Kurooka, H.3
Minoguchi, S.4
Sakai, T.5
Nomura-Okazaki, S.6
Tamura, K.7
Honjo, T.8
-
32
-
-
0034595665
-
Functional interaction between the mouse notch1 intracellular region and histone acetyltransferases PCAF and GCN5
-
Kurooka, H., and T. Honjo. 2000. Functional interaction between the mouse notch1 intracellular region and histone acetyltransferases PCAF and GCN5. J. Biol. Chem. 275:17211-17220.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 17211-17220
-
-
Kurooka, H.1
Honjo, T.2
-
33
-
-
0032403190
-
Roles of the ankyrin repeats and C-terminal region of the mouse notch1 intracellular region
-
Kurooka, H., K. Kuroda, and T. Honjo. 1998. Roles of the ankyrin repeats and C-terminal region of the mouse notch1 intracellular region. Nucleic Acids Res. 26:5448-5455.
-
(1998)
Nucleic Acids Res.
, vol.26
, pp. 5448-5455
-
-
Kurooka, H.1
Kuroda, K.2
Honjo, T.3
-
34
-
-
0027386233
-
Antineurogenic phenotypes induced by truncated Notch proteins indicate a role in signal transduction and may point to a novel function for Notch in nuclei
-
Lieber, T., S. Kidd, E. Alcamo, V. Corbin, and M. W. Young. 1993. Antineurogenic phenotypes induced by truncated Notch proteins indicate a role in signal transduction and may point to a novel function for Notch in nuclei. Genes Dev. 7:1949-1965.
-
(1993)
Genes Dev.
, vol.7
, pp. 1949-1965
-
-
Lieber, T.1
Kidd, S.2
Alcamo, E.3
Corbin, V.4
Young, M.W.5
-
35
-
-
0032493302
-
The Notch1 receptor is cleaved constitutively by a furin-like convertase
-
Logeat, F., C. Bessia, C. Brou, O. LeBail, S. Jarriault, N. G. Seidah, and A. Israel. 1998. The Notch1 receptor is cleaved constitutively by a furin-like convertase. Proc. Natl. Acad. Sci. USA 95:8108-8112.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 8108-8112
-
-
Logeat, F.1
Bessia, C.2
Brou, C.3
LeBail, O.4
Jarriault, S.5
Seidah, N.G.6
Israel, A.7
-
36
-
-
0030840415
-
Isolation and functional analysis of a cDNA for human Jagged2, a gene encoding a ligand for the Notch1 receptor
-
Luo, B., J. C. Aster, R. P. Hasserjian, F. Kuo, and J. Sklar. 1997. Isolation and functional analysis of a cDNA for human Jagged2, a gene encoding a ligand for the Notch1 receptor. Mol. Cell. Biol. 17:6057-6067.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 6057-6067
-
-
Luo, B.1
Aster, J.C.2
Hasserjian, R.P.3
Kuo, F.4
Sklar, J.5
-
37
-
-
0030693878
-
Suppressor of Hairless-independent events in Notch signaling imply novel pathway elements
-
Matsuno, K., M. J. Go, X. Sun, D. S. Eastman, and S. Artavanis-Tsakonas. 1997. Suppressor of Hairless-independent events in Notch signaling imply novel pathway elements. Development 124:4265-4273.
-
(1997)
Development
, vol.124
, pp. 4265-4273
-
-
Matsuno, K.1
Go, M.J.2
Sun, X.3
Eastman, D.S.4
Artavanis-Tsakonas, S.5
-
38
-
-
0034671686
-
Notch signaling: From the outside in
-
Mumm, J. S., and R. Kopan. 2000. Notch signaling: From the outside in. Dev. Biol. 228:151-165.
-
(2000)
Dev. Biol.
, vol.228
, pp. 151-165
-
-
Mumm, J.S.1
Kopan, R.2
-
39
-
-
0032915458
-
Notch signaling imposes two distinct blocks in the differentiation of C2C12 myoblasts
-
Nofziger, D., A. Miyamoto, K. M. Lyons, and G. Weinmaster. 1999. Notch signaling imposes two distinct blocks in the differentiation of C2C12 myoblasts. Development 126:1689-1702.
-
(1999)
Development
, vol.126
, pp. 1689-1702
-
-
Nofziger, D.1
Miyamoto, A.2
Lyons, K.M.3
Weinmaster, G.4
-
40
-
-
0029942842
-
Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles
-
Pear, W. S., J. C. Aster, M. L. Scott, R. P. Hasserjian, B. Soffer, J. Sklar, and D. Baltimore. 1996. Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles. J. Exp. Med. 183:2283-2291.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 2283-2291
-
-
Pear, W.S.1
Aster, J.C.2
Scott, M.L.3
Hasserjian, R.P.4
Soffer, B.5
Sklar, J.6
Baltimore, D.7
-
41
-
-
0034682337
-
LAG-3 is a putative transcriptional activator in the C. elegans Notch pathway
-
Petcherski, A. G., and J. Kimble. 2000. LAG-3 is a putative transcriptional activator in the C. elegans Notch pathway. Nature 405:364-368.
-
(2000)
Nature
, vol.405
, pp. 364-368
-
-
Petcherski, A.G.1
Kimble, J.2
-
42
-
-
20244389684
-
Notch1 expression in early lymphopoiesis influences B versus T lineage determination
-
Pui, J. C., D. Allman, L. Xu, S. DeRocco, F. G. Karnell, S. Bakkour, J. Y. Lee, T. Kadesch, R. R. Hardy, J. C. Aster, and W. S. Pear. 1999. Notch1 expression in early lymphopoiesis influences B versus T lineage determination. Immunity 11:299-308.
-
(1999)
Immunity
, vol.11
, pp. 299-308
-
-
Pui, J.C.1
Allman, D.2
Xu, L.3
DeRocco, S.4
Karnell, F.G.5
Bakkour, S.6
Lee, J.Y.7
Kadesch, T.8
Hardy, R.R.9
Aster, J.C.10
Pear, W.S.11
-
43
-
-
0033136717
-
Deficient T cell fate specification in mice with an induced inactivation of Notch1
-
Radtke, F., A. Wilson, G. Stark, M. Bauer, J. van Meerwijk, H. R. MacDonald, and M. Aguet. 1999. Deficient T cell fate specification in mice with an induced inactivation of Notch1. Immunity. 10:547-558.
-
(1999)
Immunity
, vol.10
, pp. 547-558
-
-
Radtke, F.1
Wilson, A.2
Stark, G.3
Bauer, M.4
Van Meerwijk, J.5
MacDonald, H.R.6
Aguet, M.7
-
44
-
-
0035856467
-
Novel Notch alleles reveal a Deltex-dependent pathway repressing neural fate
-
Ramain, P., K. Khechumian, L. Seugnet, N. Arbogast, C. Ackermann, and P. Heitzler. 2001. Novel Notch alleles reveal a Deltex-dependent pathway repressing neural fate. Curr. Biol. 11:1729-1738.
-
(2001)
Curr. Biol.
, vol.11
, pp. 1729-1738
-
-
Ramain, P.1
Khechumian, K.2
Seugnet, L.3
Arbogast, N.4
Ackermann, C.5
Heitzler, P.6
-
45
-
-
0026086474
-
Specific EGF repeats of Notch mediate interactions with Delta and Serrate: Implications for Notch as a multifunctional receptor
-
Rebay, I., R. J. Fleming, R. G. Fehon, L. Cherbas, P. Cherbas, and S. Artavanis-Tsakonas. 1991. Specific EGF repeats of Notch mediate interactions with Delta and Serrate: Implications for Notch as a multifunctional receptor. Cell 67:687-699.
-
(1991)
Cell
, vol.67
, pp. 687-699
-
-
Rebay, I.1
Fleming, R.J.2
Fehon, R.G.3
Cherbas, L.4
Cherbas, P.5
Artavanis-Tsakonas, S.6
-
46
-
-
0026554890
-
Mouse mammary tumor gene int-3: A member of the notch gene family transforms mammary epithelial cells
-
Robbins, J., B. J. Blondel, D. Gallahan, and R. Callahan. 1992. Mouse mammary tumor gene int-3: A member of the notch gene family transforms mammary epithelial cells. J. Virol. 66:2594-2599.
-
(1992)
J. Virol.
, vol.66
, pp. 2594-2599
-
-
Robbins, J.1
Blondel, B.J.2
Gallahan, D.3
Callahan, R.4
-
47
-
-
0034902568
-
Induction of cyclin D1 transcription and CDK2 activity, by Notch(ic): Implication for cell cycle disruption in transformation by Notch(ic)
-
Ronchini, C., and A. J. Capobianco. 2001. Induction of cyclin D1 transcription and CDK2 activity, by Notch(ic): Implication for cell cycle disruption in transformation by Notch(ic). Mol. Cell. Biol. 21:5925-5934.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 5925-5934
-
-
Ronchini, C.1
Capobianco, A.J.2
-
48
-
-
0023472472
-
Tricine-sodium dodecyl sulfatepolyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa
-
Schagger, H., and G. von Jagow. 1987. Tricine-sodium dodecyl sulfatepolyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa. Anal. Biochem. 166:368-379.
-
(1987)
Anal. Biochem.
, vol.166
, pp. 368-379
-
-
Schagger, H.1
Von Jagow, G.2
-
49
-
-
0032574993
-
Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain
-
Schroeter, E. H., J. A. Kisslinger, and R. Kopan. 1998. Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain. Nature 393:382-386.
-
(1998)
Nature
, vol.393
, pp. 382-386
-
-
Schroeter, E.H.1
Kisslinger, J.A.2
Kopan, R.3
-
50
-
-
0034602419
-
Presenilin-1 and -2 are molecular targets for gamma-secretase inhibitors
-
Seiffert, D., J. D. Bradley, C. M. Rominger, D. H. Rominger, F. Yang, J. E. Meredith, Jr., Q. Wang, A. H. Roach, L. A. Thompson, S. M. Spitz, J. N. Higaki, S. R. Prakash, A. P. Combs, R. A. Copeland, S. P. Arnerie Arneric, P. R. Hartig, D. W. Robertson, B. Cordell, A. M. Stern, R. E. Olson, and R. Zaczek. 2000. Presenilin-1 and -2 are molecular targets for gamma-secretase inhibitors. J. Biol. Chem. 275:34086-34091.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 34086-34091
-
-
Seiffert, D.1
Bradley, J.D.2
Rominger, C.M.3
Rominger, D.H.4
Yang, F.5
Meredith J.E., Jr.6
Wang, Q.7
Roach, A.H.8
Thompson, L.A.9
Spitz, S.M.10
Higaki, J.N.11
Prakash, S.R.12
Combs, A.P.13
Copeland, R.A.14
Arneric, S.P.15
Hartig, P.R.16
Robertson, D.W.17
Cordell, B.18
Stern, A.M.19
Olson, R.E.20
Zaczek, R.21
more..
-
51
-
-
0030453171
-
Notch signaling inhibits muscle cell differentiation through a CBF1-independent pathway
-
Shawber, C., D. Nofziger, J. J. Hsieh, C. Lindsell, O. Bogler, D. Hayward, and G. Weinmaster. 1996. Notch signaling inhibits muscle cell differentiation through a CBF1-independent pathway. Development 122:3765-3773.
-
(1996)
Development
, vol.122
, pp. 3765-3773
-
-
Shawber, C.1
Nofziger, D.2
Hsieh, J.J.3
Lindsell, C.4
Bogler, O.5
Hayward, D.6
Weinmaster, G.7
-
52
-
-
0032524325
-
Nuclear access and action of notch in vivo
-
Struhl, G., and A. Adachi. 1998. Nuclear access and action of notch in vivo. Cell 93:649-660.
-
(1998)
Cell
, vol.93
, pp. 649-660
-
-
Struhl, G.1
Adachi, A.2
-
53
-
-
0035793082
-
Presenilin-mediated transmembrane cleavage is required for Notch signal transduction in Drosophila
-
Struhl, G., and I. Greenwald. 2001. Presenilin-mediated transmembrane cleavage is required for Notch signal transduction in Drosophila. Proc. Natl. Acad. Sci. USA 98:229-234.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 229-234
-
-
Struhl, G.1
Greenwald, I.2
-
54
-
-
0035869115
-
The N-and C-terminal regions of RBP-J interact with the ankyrin repeats of Notch1 RAMIC to activate transcription
-
Tani, S., H. Kurooka, T. Aoki, N. Hashimoto, and T. Honjo. 2001. The N-and C-terminal regions of RBP-J interact with the ankyrin repeats of Notch1 RAMIC to activate transcription. Nucleic Acids Res. 29:1373-1380.
-
(2001)
Nucleic Acids Res.
, vol.29
, pp. 1373-1380
-
-
Tani, S.1
Kurooka, H.2
Aoki, T.3
Hashimoto, N.4
Honjo, T.5
-
55
-
-
0037133688
-
Notch receptor cleavage depends on but is not directly executed by presenilins
-
Taniguchi, Y., H. Karlstrom, J. Lundkvist, T. Mizutani, A. Otaka, M. Vestling, A. Bernstein, D. Donoviel, U. Lendahl, and T. Honjo. 2002. Notch receptor cleavage depends on but is not directly executed by presenilins. Proc. Natl. Acad. Sci. USA 99:4014-4019.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 4014-4019
-
-
Taniguchi, Y.1
Karlstrom, H.2
Lundkvist, J.3
Mizutani, T.4
Otaka, A.5
Vestling, M.6
Bernstein, A.7
Donoviel, D.8
Lendahl, U.9
Honjo, T.10
-
56
-
-
0030700813
-
Only a subset of the binary cell fate decisions mediated by Numb/Notch signaling in Drosophila sensory organ lineage requires Suppressor of Hairless
-
Wang, S., S. Younger-Shepherd, L. Y. Jan, and Y. N. Jan. 1997. Only a subset of the binary cell fate decisions mediated by Numb/Notch signaling in Drosophila sensory organ lineage requires Suppressor of Hairless. Development 124:4435-4446.
-
(1997)
Development
, vol.124
, pp. 4435-4446
-
-
Wang, S.1
Younger-Shepherd, S.2
Jan, L.Y.3
Jan, Y.N.4
-
57
-
-
0037150672
-
Identification of signal peptide peptidase, a presenilin-type aspartic protease
-
Weihofen, A., K. Binns, M. K. Lemberg, K. Ashman, and B. Martoglio. 2002, Identification of signal peptide peptidase, a presenilin-type aspartic protease. Science 296:2215-2218.
-
(2002)
Science
, vol.296
, pp. 2215-2218
-
-
Weihofen, A.1
Binns, K.2
Lemberg, M.K.3
Ashman, K.4
Martoglio, B.5
-
58
-
-
0035168209
-
gamma-Secretase inhibitors as molecular probes of presenilin function
-
Wolfe, M. S. 2001. gamma-Secretase inhibitors as molecular probes of presenilin function. J. Mol. Neurosci. 17:199-204.
-
(2001)
J. Mol. Neurosci.
, vol.17
, pp. 199-204
-
-
Wolfe, M.S.1
-
59
-
-
0033535553
-
Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity
-
Wolfe, M. S., W. Xia, B. L. Ostaszewski, T. S. Diehl, W. T. Kimberly, and D. J. Selkoe. 1999. Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity. Nature 398:513-517.
-
(1999)
Nature
, vol.398
, pp. 513-517
-
-
Wolfe, M.S.1
Xia, W.2
Ostaszewski, B.L.3
Diehl, T.S.4
Kimberly, W.T.5
Selkoe, D.J.6
-
60
-
-
0033662392
-
MAML1, a human homologue of drosophila mastermind, is a transcriptional coactivator for NOTCH receptors
-
Wu, L., J. C. Aster, S. C. Blacklow, R. Lake, S. Artavanis-Tsakonas, and J. D. Griffin. 2000. MAML1, a human homologue of drosophila mastermind, is a transcriptional coactivator for NOTCH receptors. Nat. Genet. 26:484-489.
-
(2000)
Nat. Genet.
, vol.26
, pp. 484-489
-
-
Wu, L.1
Aster, J.C.2
Blacklow, S.C.3
Lake, R.4
Artavanis-Tsakonas, S.5
Griffin, J.D.6
-
61
-
-
0035895087
-
A novel Notch ligand, D114, induces T-cell leukemia/lymphoma when overexpressed in mice by retroviral-mediated gene transfer
-
Yan, X. Q., U. Sarmiento, Y. Sun, G. Huang, J. Guo, T. Juan, G. Van, M. Y. Qi, S. Scully, G. Senaldi, and F. A. Fletcher. 2001. A novel Notch ligand, D114, induces T-cell leukemia/lymphoma when overexpressed in mice by retroviral-mediated gene transfer. Blood 98:3793-3799.
-
(2001)
Blood
, vol.98
, pp. 3793-3799
-
-
Yan, X.Q.1
Sarmiento, U.2
Sun, Y.3
Huang, G.4
Guo, J.5
Juan, T.6
Van, G.7
Qi, M.Y.8
Scully, S.9
Senaldi, G.10
Fletcher, F.A.11
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