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Volumn 23, Issue 2, 2003, Pages 655-664

Growth suppression of pre-T acute lymphoblastic leukemia cells by inhibition of NOTCH signaling

Author keywords

[No Author keywords available]

Indexed keywords

NOTCH RECEPTOR; PRESENILIN 1; PROTEIN INHIBITOR; RECEPTOR;

EID: 0037218811     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.23.2.655-664.2003     Document Type: Article
Times cited : (337)

References (61)
  • 1
    • 0033617522 scopus 로고    scopus 로고
    • Notch signaling: Cell fate control and signal integration in development
    • Artavanis-Tsakonas, S., M. D. Rand, and R. J. Lake. 1999. Notch signaling: Cell fate control and signal integration in development. Science 284:770-776.
    • (1999) Science , vol.284 , pp. 770-776
    • Artavanis-Tsakonas, S.1    Rand, M.D.2    Lake, R.J.3
  • 3
    • 0030945447 scopus 로고    scopus 로고
    • Oncogenic forms of NOTCH1 lacking either the primary binding site for RBP-Jκ or nuclear localization sequences retain the ability to associate with RBP-Jκ and activate transcription
    • Aster, J. C., E. S. Robertson, R. P. Hasserjian, J. R. Turner, E. Kieff, and J. Sklar. 1997. Oncogenic forms of NOTCH1 lacking either the primary binding site for RBP-Jκ or nuclear localization sequences retain the ability to associate with RBP-Jκ and activate transcription. J. Biol. Chem. 272:11336-11343.
    • (1997) J. Biol. Chem. , vol.272 , pp. 11336-11343
    • Aster, J.C.1    Robertson, E.S.2    Hasserjian, R.P.3    Turner, J.R.4    Kieff, E.5    Sklar, J.6
  • 4
    • 0033796150 scopus 로고    scopus 로고
    • Essential roles for ankyrin repeat and transactivation domains in induction of T-cell leukemia by Notch1
    • Aster, J. C., L. Xu, F. G. Karnell, V. Patriub, J. C. Pui, and W. S. Pear. 2000. Essential roles for ankyrin repeat and transactivation domains in induction of T-cell leukemia by Notch1. Mol. Cell. Biol. 20:7505-7515.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 7505-7515
    • Aster, J.C.1    Xu, L.2    Karnell, F.G.3    Patriub, V.4    Pui, J.C.5    Pear, W.S.6
  • 5
    • 0033944273 scopus 로고    scopus 로고
    • Aspartate mutations in presenilin and gamma-secretase inhibitors both impair notch1 proteolysis and nuclear translocation with relative preservation of notch1 signaling
    • Berezovska, O., C. Jack, P. McLean, J. C. Aster, C. Hicks, W. Xia, M. S. Wolfe, W. T. Kimberly, G. Weinmaster, D. J. Selkoe, and B. T. Hyman. 2000. Aspartate mutations in presenilin and gamma-secretase inhibitors both impair notch1 proteolysis and nuclear translocation with relative preservation of notch1 signaling. J. Neurochem. 75:583-593.
    • (2000) J. Neurochem. , vol.75 , pp. 583-593
    • Berezovska, O.1    Jack, C.2    McLean, P.3    Aster, J.C.4    Hicks, C.5    Xia, W.6    Wolfe, M.S.7    Kimberly, W.T.8    Weinmaster, G.9    Selkoe, D.J.10    Hyman, B.T.11
  • 6
    • 0031030361 scopus 로고    scopus 로고
    • Germ-line tumor formation caused by activation of glp-1, a Caenorhabditis elegans member of the Notch family of receptors
    • Berry, L. W., B. Westlund, and T. Schedl. 1997. Germ-line tumor formation caused by activation of glp-1, a Caenorhabditis elegans member of the Notch family of receptors. Development 124:925-936.
    • (1997) Development , vol.124 , pp. 925-936
    • Berry, L.W.1    Westlund, B.2    Schedl, T.3
  • 10
    • 0032904239 scopus 로고    scopus 로고
    • Notch1-induced delay of human hematopoietic progenitor cell differentiation is associated with altered cell cycle kinetics
    • Carlesso, N., J. C. Aster, J. Sklar, and D. T. Scadden. 1999. Notch1-induced delay of human hematopoietic progenitor cell differentiation is associated with altered cell cycle kinetics. Blood 93:838-848.
    • (1999) Blood , vol.93 , pp. 838-848
    • Carlesso, N.1    Aster, J.C.2    Sklar, J.3    Scadden, D.T.4
  • 11
    • 0034038237 scopus 로고    scopus 로고
    • The Abruptex domain of Notch regulates negative interactions between Notch, its ligands and Fringe
    • De Celis, J. F., and S. J. Bray. 2000. The Abruptex domain of Notch regulates negative interactions between Notch, its ligands and Fringe. Development 127:1291-1302.
    • (2000) Development , vol.127 , pp. 1291-1302
    • De Celis, J.F.1    Bray, S.J.2
  • 12
    • 0032442040 scopus 로고    scopus 로고
    • Correlating notch signaling with thymocyte maturation
    • Deftos, M. L., Y. W. He, E. W. Ojala, and M. J. Bevan. 1998. Correlating notch signaling with thymocyte maturation. Immunity 9:777-786.
    • (1998) Immunity , vol.9 , pp. 777-786
    • Deftos, M.L.1    He, Y.W.2    Ojala, E.W.3    Bevan, M.J.4
  • 15
    • 0034608814 scopus 로고    scopus 로고
    • SEL-8, a nuclear protein required for LIN-12 and GLP-1 signaling in Caenorhabditis elegans
    • Doyle, T. G., C. Wen, and I. Greenwald. 2000. SEL-8, a nuclear protein required for LIN-12 and GLP-1 signaling in Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA 97:7877-7881.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 7877-7881
    • Doyle, T.G.1    Wen, C.2    Greenwald, I.3
  • 16
    • 0025856717 scopus 로고
    • TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms
    • Ellisen, L. W., J. Bird, D. C. West, A. L. Soreng, T. C. Reynolds, S. D. Smith, and J. Sklar. 1991. TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms. Cell 66:649-661.
    • (1991) Cell , vol.66 , pp. 649-661
    • Ellisen, L.W.1    Bird, J.2    West, D.C.3    Soreng, A.L.4    Reynolds, T.C.5    Smith, S.D.6    Sklar, J.7
  • 18
    • 0032751132 scopus 로고    scopus 로고
    • SEL-5, a serine/threonine kinase that facilitates lin-12 activity in Caenorhabditis elegans
    • Fares, H., and I. Greenwald. 1999. SEL-5, a serine/threonine kinase that facilitates lin-12 activity in Caenorhabditis elegans. Genetics 153:1641-1654.
    • (1999) Genetics , vol.153 , pp. 1641-1654
    • Fares, H.1    Greenwald, I.2
  • 19
    • 0027378244 scopus 로고
    • An activated Notch receptor blocks cell-fate commitment in the developing Drosophila eye
    • Fortini, M. E., I. Rebay, L. A. Caron, and S. Artavanis-Tsakonas. 1993. An activated Notch receptor blocks cell-fate commitment in the developing Drosophila eye. Nature 365:555-557.
    • (1993) Nature , vol.365 , pp. 555-557
    • Fortini, M.E.1    Rebay, I.2    Caron, L.A.3    Artavanis-Tsakonas, S.4
  • 20
    • 0036606776 scopus 로고    scopus 로고
    • Mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complex
    • Fryer, C. J., E. Lamar, I. Turbachova, C. Kintner, and K. A. Jones. 2002. Mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complex. Genes Dev. 16:1397-1411.
    • (2002) Genes Dev. , vol.16 , pp. 1397-1411
    • Fryer, C.J.1    Lamar, E.2    Turbachova, I.3    Kintner, C.4    Jones, K.A.5
  • 21
    • 0031835079 scopus 로고    scopus 로고
    • Cell proliferation control by Notch signaling in Drosophila development
    • Go, M. J., D. S. Eastman, and S. Artavanis-Tsakonas. 1998. Cell proliferation control by Notch signaling in Drosophila development. Development 125:2031-2040.
    • (1998) Development , vol.125 , pp. 2031-2040
    • Go, M.J.1    Eastman, D.S.2    Artavanis-Tsakonas, S.3
  • 22
    • 0025316499 scopus 로고
    • Analysis of gain-of-function mutations of the lin-12 gene of Caenorhabditis elegans
    • Greenwald, I., and G. Seydoux. 1990. Analysis of gain-of-function mutations of the lin-12 gene of Caenorhabditis elegans. Nature 346:197-199.
    • (1990) Nature , vol.346 , pp. 197-199
    • Greenwald, I.1    Seydoux, G.2
  • 23
    • 0028133036 scopus 로고
    • Mediation of Epstein-Barr virus EBNA2 transactivation by recombination signal-binding protein Jκ
    • Henkel, T., P. D. Ling, S. D. Hayward, and M. G. Peterson. 1994. Mediation of Epstein-Barr virus EBNA2 transactivation by recombination signal-binding protein Jκ. Science 265:92-95.
    • (1994) Science , vol.265 , pp. 92-95
    • Henkel, T.1    Ling, P.D.2    Hayward, S.D.3    Peterson, M.G.4
  • 24
    • 0030063909 scopus 로고    scopus 로고
    • Truncated mammalian Notch1 activates CBF1/RBPJκ-repressed genes by a mechanism resembling that of Epstein-Barr virus EBNA2
    • Hsieh, J. J., T. Henkel, P. Salmon, E. Robey, M. G. Peterson, and S. D. Hayward. 1996. Truncated mammalian Notch1 activates CBF1/RBPJκ-repressed genes by a mechanism resembling that of Epstein-Barr virus EBNA2. Mol. Cell. Biol. 16:952-959.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 952-959
    • Hsieh, J.J.1    Henkel, T.2    Salmon, P.3    Robey, E.4    Peterson, M.G.5    Hayward, S.D.6
  • 25
    • 0034702303 scopus 로고    scopus 로고
    • Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1
    • Huppert, S. S., A. Le, E. H. Schroeter, J. S. Mumm, M. T. Saxena, L. A. Milner, and R. Kopan. 2000. Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1. Nature 405:966-970.
    • (2000) Nature , vol.405 , pp. 966-970
    • Huppert, S.S.1    Le, A.2    Schroeter, E.H.3    Mumm, J.S.4    Saxena, M.T.5    Milner, L.A.6    Kopan, R.7
  • 27
    • 0034024625 scopus 로고    scopus 로고
    • Neoplastic transformation by Notch requires nuclear localization
    • Jeffries, S., and A. J. Capobianco. 2000. Neoplastic transformation by Notch requires nuclear localization. Mol. Cell. Biol. 20:3928-3941.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 3928-3941
    • Jeffries, S.1    Capobianco, A.J.2
  • 28
    • 0036096912 scopus 로고    scopus 로고
    • Characterization of a high-molecular-weight Notch complex in the nucleus of Notch(ic)-transformed RKE cells and in a human T-cell leukemia cell line
    • Jeffries, S., D. J. Robbins, and A. J. Capobianco. 2002. Characterization of a high-molecular-weight Notch complex in the nucleus of Notch(ic)-transformed RKE cells and in a human T-cell leukemia cell line. Mol. Cell. Biol. 22:3927-3941.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 3927-3941
    • Jeffries, S.1    Robbins, D.J.2    Capobianco, A.J.3
  • 29
    • 0033556251 scopus 로고    scopus 로고
    • Protective effects of notch-1 on TCR-induced apoptosis
    • Jehn, B. M., W. Bielke, W. S. Pear, and B. A. Osborne. 1999. Protective effects of notch-1 on TCR-induced apoptosis. J Immunol. 162:635-638.
    • (1999) J Immunol. , vol.162 , pp. 635-638
    • Jehn, B.M.1    Bielke, W.2    Pear, W.S.3    Osborne, B.A.4
  • 30
    • 0036566557 scopus 로고    scopus 로고
    • Activated Notch1 signaling promotes tumor cell proliferation and survival in Hodgkin and anaplastic large cell lymphoma
    • Jundt, F., I. Anagnostopoulos, R. Forster, S. Mathas, H. Stein, and B. Dorken. 2002. Activated Notch1 signaling promotes tumor cell proliferation and survival in Hodgkin and anaplastic large cell lymphoma. Blood 99:3398-3403.
    • (2002) Blood , vol.99 , pp. 3398-3403
    • Jundt, F.1    Anagnostopoulos, I.2    Forster, R.3    Mathas, S.4    Stein, H.5    Dorken, B.6
  • 32
    • 0034595665 scopus 로고    scopus 로고
    • Functional interaction between the mouse notch1 intracellular region and histone acetyltransferases PCAF and GCN5
    • Kurooka, H., and T. Honjo. 2000. Functional interaction between the mouse notch1 intracellular region and histone acetyltransferases PCAF and GCN5. J. Biol. Chem. 275:17211-17220.
    • (2000) J. Biol. Chem. , vol.275 , pp. 17211-17220
    • Kurooka, H.1    Honjo, T.2
  • 33
    • 0032403190 scopus 로고    scopus 로고
    • Roles of the ankyrin repeats and C-terminal region of the mouse notch1 intracellular region
    • Kurooka, H., K. Kuroda, and T. Honjo. 1998. Roles of the ankyrin repeats and C-terminal region of the mouse notch1 intracellular region. Nucleic Acids Res. 26:5448-5455.
    • (1998) Nucleic Acids Res. , vol.26 , pp. 5448-5455
    • Kurooka, H.1    Kuroda, K.2    Honjo, T.3
  • 34
    • 0027386233 scopus 로고
    • Antineurogenic phenotypes induced by truncated Notch proteins indicate a role in signal transduction and may point to a novel function for Notch in nuclei
    • Lieber, T., S. Kidd, E. Alcamo, V. Corbin, and M. W. Young. 1993. Antineurogenic phenotypes induced by truncated Notch proteins indicate a role in signal transduction and may point to a novel function for Notch in nuclei. Genes Dev. 7:1949-1965.
    • (1993) Genes Dev. , vol.7 , pp. 1949-1965
    • Lieber, T.1    Kidd, S.2    Alcamo, E.3    Corbin, V.4    Young, M.W.5
  • 36
    • 0030840415 scopus 로고    scopus 로고
    • Isolation and functional analysis of a cDNA for human Jagged2, a gene encoding a ligand for the Notch1 receptor
    • Luo, B., J. C. Aster, R. P. Hasserjian, F. Kuo, and J. Sklar. 1997. Isolation and functional analysis of a cDNA for human Jagged2, a gene encoding a ligand for the Notch1 receptor. Mol. Cell. Biol. 17:6057-6067.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 6057-6067
    • Luo, B.1    Aster, J.C.2    Hasserjian, R.P.3    Kuo, F.4    Sklar, J.5
  • 37
    • 0030693878 scopus 로고    scopus 로고
    • Suppressor of Hairless-independent events in Notch signaling imply novel pathway elements
    • Matsuno, K., M. J. Go, X. Sun, D. S. Eastman, and S. Artavanis-Tsakonas. 1997. Suppressor of Hairless-independent events in Notch signaling imply novel pathway elements. Development 124:4265-4273.
    • (1997) Development , vol.124 , pp. 4265-4273
    • Matsuno, K.1    Go, M.J.2    Sun, X.3    Eastman, D.S.4    Artavanis-Tsakonas, S.5
  • 38
    • 0034671686 scopus 로고    scopus 로고
    • Notch signaling: From the outside in
    • Mumm, J. S., and R. Kopan. 2000. Notch signaling: From the outside in. Dev. Biol. 228:151-165.
    • (2000) Dev. Biol. , vol.228 , pp. 151-165
    • Mumm, J.S.1    Kopan, R.2
  • 39
    • 0032915458 scopus 로고    scopus 로고
    • Notch signaling imposes two distinct blocks in the differentiation of C2C12 myoblasts
    • Nofziger, D., A. Miyamoto, K. M. Lyons, and G. Weinmaster. 1999. Notch signaling imposes two distinct blocks in the differentiation of C2C12 myoblasts. Development 126:1689-1702.
    • (1999) Development , vol.126 , pp. 1689-1702
    • Nofziger, D.1    Miyamoto, A.2    Lyons, K.M.3    Weinmaster, G.4
  • 40
    • 0029942842 scopus 로고    scopus 로고
    • Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles
    • Pear, W. S., J. C. Aster, M. L. Scott, R. P. Hasserjian, B. Soffer, J. Sklar, and D. Baltimore. 1996. Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles. J. Exp. Med. 183:2283-2291.
    • (1996) J. Exp. Med. , vol.183 , pp. 2283-2291
    • Pear, W.S.1    Aster, J.C.2    Scott, M.L.3    Hasserjian, R.P.4    Soffer, B.5    Sklar, J.6    Baltimore, D.7
  • 41
    • 0034682337 scopus 로고    scopus 로고
    • LAG-3 is a putative transcriptional activator in the C. elegans Notch pathway
    • Petcherski, A. G., and J. Kimble. 2000. LAG-3 is a putative transcriptional activator in the C. elegans Notch pathway. Nature 405:364-368.
    • (2000) Nature , vol.405 , pp. 364-368
    • Petcherski, A.G.1    Kimble, J.2
  • 45
    • 0026086474 scopus 로고
    • Specific EGF repeats of Notch mediate interactions with Delta and Serrate: Implications for Notch as a multifunctional receptor
    • Rebay, I., R. J. Fleming, R. G. Fehon, L. Cherbas, P. Cherbas, and S. Artavanis-Tsakonas. 1991. Specific EGF repeats of Notch mediate interactions with Delta and Serrate: Implications for Notch as a multifunctional receptor. Cell 67:687-699.
    • (1991) Cell , vol.67 , pp. 687-699
    • Rebay, I.1    Fleming, R.J.2    Fehon, R.G.3    Cherbas, L.4    Cherbas, P.5    Artavanis-Tsakonas, S.6
  • 46
    • 0026554890 scopus 로고
    • Mouse mammary tumor gene int-3: A member of the notch gene family transforms mammary epithelial cells
    • Robbins, J., B. J. Blondel, D. Gallahan, and R. Callahan. 1992. Mouse mammary tumor gene int-3: A member of the notch gene family transforms mammary epithelial cells. J. Virol. 66:2594-2599.
    • (1992) J. Virol. , vol.66 , pp. 2594-2599
    • Robbins, J.1    Blondel, B.J.2    Gallahan, D.3    Callahan, R.4
  • 47
    • 0034902568 scopus 로고    scopus 로고
    • Induction of cyclin D1 transcription and CDK2 activity, by Notch(ic): Implication for cell cycle disruption in transformation by Notch(ic)
    • Ronchini, C., and A. J. Capobianco. 2001. Induction of cyclin D1 transcription and CDK2 activity, by Notch(ic): Implication for cell cycle disruption in transformation by Notch(ic). Mol. Cell. Biol. 21:5925-5934.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 5925-5934
    • Ronchini, C.1    Capobianco, A.J.2
  • 48
    • 0023472472 scopus 로고
    • Tricine-sodium dodecyl sulfatepolyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa
    • Schagger, H., and G. von Jagow. 1987. Tricine-sodium dodecyl sulfatepolyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa. Anal. Biochem. 166:368-379.
    • (1987) Anal. Biochem. , vol.166 , pp. 368-379
    • Schagger, H.1    Von Jagow, G.2
  • 49
    • 0032574993 scopus 로고    scopus 로고
    • Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain
    • Schroeter, E. H., J. A. Kisslinger, and R. Kopan. 1998. Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain. Nature 393:382-386.
    • (1998) Nature , vol.393 , pp. 382-386
    • Schroeter, E.H.1    Kisslinger, J.A.2    Kopan, R.3
  • 52
    • 0032524325 scopus 로고    scopus 로고
    • Nuclear access and action of notch in vivo
    • Struhl, G., and A. Adachi. 1998. Nuclear access and action of notch in vivo. Cell 93:649-660.
    • (1998) Cell , vol.93 , pp. 649-660
    • Struhl, G.1    Adachi, A.2
  • 53
    • 0035793082 scopus 로고    scopus 로고
    • Presenilin-mediated transmembrane cleavage is required for Notch signal transduction in Drosophila
    • Struhl, G., and I. Greenwald. 2001. Presenilin-mediated transmembrane cleavage is required for Notch signal transduction in Drosophila. Proc. Natl. Acad. Sci. USA 98:229-234.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 229-234
    • Struhl, G.1    Greenwald, I.2
  • 54
    • 0035869115 scopus 로고    scopus 로고
    • The N-and C-terminal regions of RBP-J interact with the ankyrin repeats of Notch1 RAMIC to activate transcription
    • Tani, S., H. Kurooka, T. Aoki, N. Hashimoto, and T. Honjo. 2001. The N-and C-terminal regions of RBP-J interact with the ankyrin repeats of Notch1 RAMIC to activate transcription. Nucleic Acids Res. 29:1373-1380.
    • (2001) Nucleic Acids Res. , vol.29 , pp. 1373-1380
    • Tani, S.1    Kurooka, H.2    Aoki, T.3    Hashimoto, N.4    Honjo, T.5
  • 56
    • 0030700813 scopus 로고    scopus 로고
    • Only a subset of the binary cell fate decisions mediated by Numb/Notch signaling in Drosophila sensory organ lineage requires Suppressor of Hairless
    • Wang, S., S. Younger-Shepherd, L. Y. Jan, and Y. N. Jan. 1997. Only a subset of the binary cell fate decisions mediated by Numb/Notch signaling in Drosophila sensory organ lineage requires Suppressor of Hairless. Development 124:4435-4446.
    • (1997) Development , vol.124 , pp. 4435-4446
    • Wang, S.1    Younger-Shepherd, S.2    Jan, L.Y.3    Jan, Y.N.4
  • 57
    • 0037150672 scopus 로고    scopus 로고
    • Identification of signal peptide peptidase, a presenilin-type aspartic protease
    • Weihofen, A., K. Binns, M. K. Lemberg, K. Ashman, and B. Martoglio. 2002, Identification of signal peptide peptidase, a presenilin-type aspartic protease. Science 296:2215-2218.
    • (2002) Science , vol.296 , pp. 2215-2218
    • Weihofen, A.1    Binns, K.2    Lemberg, M.K.3    Ashman, K.4    Martoglio, B.5
  • 58
    • 0035168209 scopus 로고    scopus 로고
    • gamma-Secretase inhibitors as molecular probes of presenilin function
    • Wolfe, M. S. 2001. gamma-Secretase inhibitors as molecular probes of presenilin function. J. Mol. Neurosci. 17:199-204.
    • (2001) J. Mol. Neurosci. , vol.17 , pp. 199-204
    • Wolfe, M.S.1
  • 59
    • 0033535553 scopus 로고    scopus 로고
    • Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity
    • Wolfe, M. S., W. Xia, B. L. Ostaszewski, T. S. Diehl, W. T. Kimberly, and D. J. Selkoe. 1999. Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity. Nature 398:513-517.
    • (1999) Nature , vol.398 , pp. 513-517
    • Wolfe, M.S.1    Xia, W.2    Ostaszewski, B.L.3    Diehl, T.S.4    Kimberly, W.T.5    Selkoe, D.J.6
  • 60
    • 0033662392 scopus 로고    scopus 로고
    • MAML1, a human homologue of drosophila mastermind, is a transcriptional coactivator for NOTCH receptors
    • Wu, L., J. C. Aster, S. C. Blacklow, R. Lake, S. Artavanis-Tsakonas, and J. D. Griffin. 2000. MAML1, a human homologue of drosophila mastermind, is a transcriptional coactivator for NOTCH receptors. Nat. Genet. 26:484-489.
    • (2000) Nat. Genet. , vol.26 , pp. 484-489
    • Wu, L.1    Aster, J.C.2    Blacklow, S.C.3    Lake, R.4    Artavanis-Tsakonas, S.5    Griffin, J.D.6
  • 61
    • 0035895087 scopus 로고    scopus 로고
    • A novel Notch ligand, D114, induces T-cell leukemia/lymphoma when overexpressed in mice by retroviral-mediated gene transfer
    • Yan, X. Q., U. Sarmiento, Y. Sun, G. Huang, J. Guo, T. Juan, G. Van, M. Y. Qi, S. Scully, G. Senaldi, and F. A. Fletcher. 2001. A novel Notch ligand, D114, induces T-cell leukemia/lymphoma when overexpressed in mice by retroviral-mediated gene transfer. Blood 98:3793-3799.
    • (2001) Blood , vol.98 , pp. 3793-3799
    • Yan, X.Q.1    Sarmiento, U.2    Sun, Y.3    Huang, G.4    Guo, J.5    Juan, T.6    Van, G.7    Qi, M.Y.8    Scully, S.9    Senaldi, G.10    Fletcher, F.A.11


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.