Phosphorylation of Ser2078 Modulates the Notch2 Function in 32D Cell Differentiation

Journal of Biological Chemistry

Volumn 276, Issue 48, 2001, Pages 44873-44880

  Inglés Esteve, Julia ^a   Espinosa, Lluis ^a   Milner, Laurie A ^b   Caelles, Carme ^c   Bigas, Anna ^a  

^a Institut de Recerca Oncologica   (Spain)

^b Fred Hutchinson Cancer Research Center   (United States)

^c UNIVERSITY OF BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; PROTEINS; TISSUE;

PHOSPHORYLATION;

CELLS;

AMINO ACID; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; NOTCH RECEPTOR; SERINE; THREONINE; CELL SURFACE RECEPTOR; CYTOKINE; NOTCH 2 PROTEIN; NOTCH-2 PROTEIN;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; CELL DIFFERENTIATION; CELL FATE; CYTOKINE RESPONSIVE ELEMENT; EMBRYO DEVELOPMENT; HOMEOSTASIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; AMINO ACID SEQUENCE; ANIMAL; CELL CULTURE; CHEMISTRY; FLUORESCENCE MICROSCOPY; GENE DELETION; IMMUNOBLOTTING; METABOLISM; MOLECULAR GENETICS; MOUSE; PHOSPHORYLATION; PHYSIOLOGY; PLASMID; PROTEIN TERTIARY STRUCTURE; RAT; SEQUENCE HOMOLOGY; TIME; TRANSACTIVATION; WESTERN BLOTTING;

ANIMALIA;

AMINO ACID SEQUENCE; AMINO ACIDS; ANIMAL; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELLS, CULTURED; CYTOKINES; GENE DELETION; GRANULOCYTE COLONY-STIMULATING FACTOR; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; IMMUNOBLOTTING; MICE; MICROSCOPY, FLUORESCENCE; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; PLASMIDS; PROTEIN STRUCTURE, TERTIARY; RATS; RECEPTORS, CELL SURFACE; SEQUENCE HOMOLOGY, AMINO ACID; SERINE; SIGNAL TRANSDUCTION; SUPPORT, NON-U.S. GOV'T; THREONINE; TIME FACTORS; TRANS-ACTIVATION (GENETICS);

EID: 0035977049     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M104703200     Document Type: Article

References (70)

1. Egan, S. E., St Pierre, B., and Leow, C. C. (1998) Curr. Top. Microbiol. Immunol. 228, 273-324
2. Ellisen, L. W., Bird, J., West, D. C., Soreng, A. L., Reynolds, T. C., Smith, S. D., and Sklar, J. (1991) Cell 66, 649-661
3. Weinmaster, G., Roberts, V. J., and Lemke, G. (1992) Development 116, 931-941
4. Lardelli, M., Dahlstrand, J., and Lendahl, U. (1994) Mech. Dev 46, 123-136
5. Uyttendaele, H., Marazzi, G., Wu, G., Yan, Q., Sassoon, D., and Kitajewski, J. (1996) Development 122, 2251-2259
6. Heitzler, P., and Simpson, P. (1991) Cell 64, 1083-1092
7. Blobel, C. P. (2000) Curr. Opin. Cell Biol. 12, 606-612
8. Fortini, M. E., Rebay, I., Caron, L. A., and Artavanis-Tsakonas, S. (1993) Nature 365, 555-557
9. Struhl, G., Fitzgerald, K., and Greenwald, I. (1993) Cell 74, 331-345
10. Kopan, R., Nye, J. S., and Weintraub, H. (1994) Development 120, 2385-2396
11. Milner, L. A., Bigas, A., Kopan, R., Brashem-Stein, C., Bernstein, I. D., and Martin, D. I. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 13014-13019
12. Swiatek, P. J., Lindsell, C. E., del Amo, F. F., Weinmaster, G., and Gridley, T. (1994) Genes Dev. 8, 707-719
13. Hamada, Y., Kadokawa, Y., Okabe, M., Ikawa, M., Coleman, J. R., and Tsujimoto, Y. (1999) Development 126, 3415-3424
14. Lindsell, C. E., Boulter, J., diSibio, G., Gossler, A., and Weinmaster, G. (1996) Mol. Cell Neurosci. 8, 14-27
15. Bao, Z. Z., and Cepko, C. L. (1997) J. Neurosci. (4),1425-1434
16. Mitsiadis, T. A., Lardelli, M., Lendahl, U., and Thesleff, I. (1995) J. Cell Biol. 130, 407-418
17. Kato, H., Sakai, T., Tamura, K., Minoguchi, S., Shirayoshi, Y., Hamada, Y., Tsujimoto, Y., and Honjo, T. (1996) FEBS Lett. (2-3),221-224
18. Ordentlich, P., Lin, A., Shen, C. P., Blaumueller, C., Matsuno, K., Artavanis Tsakonas, S., and Kadesch, T. (1998) Mol. Cell. Biol. 18, 2230-2239
19. Milner, L. A., Kopan, R., Martin, D. I., and Bernstein, I. D. (1994) Blood 83, 2057-2062
20. Singh, N., Phillips, R. A., Iscove, N. N., and Egan, S. E. (2000) Exp. Hematol. 28, 527-534
21. Tsai, S., Fero, J., and Bartelmez, S. (2000) Blood 96, 950-957
22. Robey, E., Chang, D., Itano, A., Cado, D., Alexander, H., Lans, D., Weinmaster, G., and Salmon, P. (1996) Cell 87, 483-492
23. Pui, J. C., Allman, D., Xu, L., DeRocco, S., Karnell, F. G., Bakkour, S., Lee, J. Y., Kadesch, T., Hardy, R. R., Aster, J. C., and Pear, W. S. (1999) Immunity 11, 299-308
24. Radtke, F., Ferrero, I., Wilson, A., Lees, R., Aguet, M., and MacDonald, H. R. (2000) J. Exp. Med. 191, 1085-1094
25. Bigas, A., Martin, D. I., and Milner, L. A. (1998) Mol. Cell. Biol. 18, 2324-2333
26. Carlesso, N., Aster, J. C., Sklar, J., and Scadden, D. T. (1999) Blood 93, 838-848
27. Schroeder, T., and Just, U. (2000) EMBO J. 19, 2558-2568
28. Lam, L. T., Ronchini, C., Norton, J., Capobianco, A. J., and Bresnick, E. H. (2000) J. Biol. Chem. 275, 19676-19684
29. Shelly, L. L., Fuchs, C., and Miele, L. (1999) J. Cell. Biochem. 73, 164-175
30. Jones, P., May, G., Healy, L., Brown, J., Hoyne, G., Delassus, S., and Enver, T. (1998) Blood 92, 1505-1511
31. Varnum-Finney, B., Purton, L. E., Yu, M., Brashem-Stein, C., Flowers, D., Staats, S., Moore, K. A., Le Roux, I., Mann, R., Gray, G., Artavanis-Tsakonas, S., and Bernstein, I. D. (1998) Blood 91, 4084-4091
32. Han, W., Ye, Q., and Moore, M. A. (2000) Blood 95, 1616-1625
33. Walker, L., Lynch, M., Silverman, S., Fraser, J., Boulter, J., Weinmaster, G., and Gasson, J. C. (1999) Stem Cells 17, 162-171
34. Moloney, D. J., Shair, L. H., Lu, F. M., Xia, J., Locke, R., Matta, K. L., and Haltiwanger, R. S. (2000) J. Biol. Chem. 275, 9604-9611
35. Kidd, S., Lieber, T., and Young, M. W. (1998) Genes Dev. 12, 3728-3740
36. Bruckner, K., Perez, L., Clausen, H., and Cohen, S. (2000) Nature 406, 411-415
37. Moloney, D. J., Panin, V. M., Johnston, S. H., Chen, J., Shao, L., Wilson, R., Wang, Y., Stanley, P., Irvine, K. D., Haltiwanger, R. S., and Vogt, T. F. (2000) Nature 406, 369-375
38. Hicks, C., Johnston, S. H., diSibio, G., Collazo, A., Vogt, T. F., and Weinmaster, G. (2000) Nat. Cell Biol. 2, 515-520
39. Redmond, L., Oh, S. R., Hicks, C., Weinmaster, G., and Ghosh, A. (2000) Nat. Neurosci. 3, 30-40
40. Shimizu, K., Chiba, S., Hosoya, N., Kumano, K., Saito, T., Kurokawa, M., Kanda, Y., Hamada, Y., and Hirai, H. (2000) Mol. Cell. Biol. 20, 6913-6922
41. Ronchini, C., and Capobianco, A. J. (2000) Oncogene 19, 3914-3924
42. Li, L., Milner, L. A., Deng, Y., Iwata, M., Banta, A., Graf, L., Marcovina, S., Friedman, C., Trask, B. J., Hood, L., and Torok Storb, B. (1998) Immunity 8, 43-55
43. Greenberger, J. S., Sakakeeny, M. A., Humphries, R. K., Eaves, C. J., and Eckner, R. J. (1983) Proc. Natl. Acad. Sci. U. S. A. 80, 2931-2935
44. Luo, K. X., Hurley, T. R., and Sefton, B. M. (1991) Methods Enzymol. 201, 149-152
45. Ohtsuka, T., Ishibashi, M., Gradwohl, G., Nakanishi, S., Guillemot, F., and Kageyama, R. (1999) EMBO J. 18, 2196-2207
46. Robey, E. (1997) Curr. Opin. Genet. Dev. 7, 551-557
47. Milner, L. A., and Bigas, A. (1999) Blood 93, 2431-2448
48. Blaumueller, C. M., Qi, H., Zagouras, P., and Artavanis Tsakonas, S. (1997) Cell 90, 281-291
49. Song, W., Nadeau, P., Yuan, M., Yang, X., Shen, J., and Yankner, B. A. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 6959-6963
50. Zhang, Z., Nadeau, P., Song, W., Donoviel, D., Yuan, M., Bernstein, A., and Yankner, B. A. (2000) Nat. Cell Biol. 2, 463-465
51. Sotillos, S., Roch, F., and Campuzano, S. (1997) Development 124, 4769-4779
52. Brou, C., Logeat, F., Gupta, N., Bessia, C., LeBail, O., Doedens, J. R., Cumano, A., Roux, P., Black, R. A., and Israel, A. (2000) Mol. Cell 5, 207-216
53. Suzuki, K., Hino, M., Hato, F., Tatsumi, N., and Kitagawa, S. (1999) Blood 93, 341-349
54. Ikeya, T., and Hayashi, S. (1999) Development 126, 4455-4463
55. Zeechini, V., Brennan, K., and Martinez-Arias, A. (1999) Curr. Biol. 9, 460-469
56. Berset, T., Hoier, E. F., Battu, G., Canevascini, S., and Hajnal, A. (2001) Science 291, 1055-1058
57. Washburn, T., Schweighoffer, E., Gridley, T., Chang, D., Fowlkes, B. J., Cado, D., and Robey, E. (1997) Cell 88, 833-843
58. Jehn, B. M., Bielke, W., Pear, W. S., and Osborne, B. A. (1999) J. Immunol. 162, 635-638
59. Ohishi, K., Varnum-Finney, B., Flowers, D., Anasetti, C., Myerson, D., and Bernstein, I. D. (2000) Blood 95, 2847-2854
60. Baonza, A., and Garcia-Bellido, A. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 2609-2614
61. Johnston, L. A., and Edgar, B. A. (1998) Nature (6688), 82-84
62. Varnum-Finney, B., Xu, L., Brashem-Stein, C., Nourigat, C., Flowers, D., Bakkour, S., Pear, W. S., and Bernstein, I. D. (2000) Nat. Med. 6, 1278-1281
63. Osborne, B., and Miele, L. (1999) Immunity 11, 653-663
64. Tan-Pertel, H. T., Walker, L., Browning, D., Miyamoto, A., Weinmaster, G., and Gasson, J. C. (2000) J. Immunol. 165, 4428-4436
65. Artavanis-Tsakonas, S., Rand, M. D., and Lake, R. J. (1999) Science 284, 770-776
66. Shawber, C., Nofziger, D., Hsieh, J. J., Lindsell, C., Bigler, O., Hayward, D., and Weinmaster, G. (1996) Development 122, 3765-3773
67. Matsuno, K., Go, M. J., Sun, X., Eastman, D. S., and Artavanis Tsakonas, S. (1997) Development 124, 4265-4273
68. Tamura, K., Taniguchi, Y., Minoguchi, S., Sakai, T., Tun, T., Furukawa, T., and Honjo, T. (1995) Curr. Biol. 5, 1416-1423
69. Axelrod, J. D., Matsuno, K., Artavanis Tsakonas, S., and Perrimon, N. (1996) Science 271, 1826-1832
70. Jeffries, S., and Capobianco, A. J. (2000) Mol. Cell. Biol. 20, 3928-3941