Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1

Science

Volumn 333, Issue 6046, 2011, Pages 1154-1157

  Agrawal, Nishant ^a,b   Frederick, Mitchell J ^c   Pickering, Curtis R ^c   Bettegowda, Chetan ^a,b   Chang, Kyle ^d   Li, Ryan J ^a   Fakhry, Carole ^a   Xie, Tong Xin ^c   Zhang, Jiexin ^c   Wang, Jing ^c   Zhang, Nianxiang ^c   El Naggar, Adel K ^c   Jasser, Samar A ^c   Weinstein, John N ^c   Treviño, Lisa ^d   Drummond, Jennifer A ^d   Muzny, Donna M ^d   Wu, Yuanqing ^d   Wood, Laura D ^a   Hruban, Ralph H ^a   Westra, William H ^a   Koch, Wayne M ^a   Califano, Joseph A ^a,e   Gibbs, Richard A ^d,e   Sidransky, David ^a   Vogelstein, Bert ^b   Velculescu, Victor E ^b   Papadopoulos, Nickolas ^b   Wheeler, David A ^d   Kinzler, Kenneth W ^b   Myers, Jeffrey N ^c   more..

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

^e GREATER BALTIMORE MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2A; EPHRIN RECEPTOR A7; NOTCH1 RECEPTOR; PROTEIN P53;

CANCER; CYTOLOGY; GENE EXPRESSION; GENETIC ANALYSIS; MUTATION; PUBLIC HEALTH; TOBACCO; TUMOR;

ARTICLE; CLINICAL ARTICLE; EXOME; GENE DELETION; GENE DOSAGE; GENE IDENTIFICATION; GENE INSERTION; GENE MUTATION; GENE SEQUENCE; GENETIC ANALYSIS; HEAD AND NECK CARCINOMA; HUMAN; INDEL MUTATION; MISSENSE MUTATION; NONSENSE MUTATION; ONCOGENE; ONCOGENE H RAS; PRIORITY JOURNAL; SMOKING; SQUAMOUS CELL CARCINOMA; WART VIRUS;

CARCINOMA; CARCINOMA, SQUAMOUS CELL; CELL CYCLE PROTEINS; CODON, NONSENSE; EXONS; F-BOX PROTEINS; GENE DOSAGE; GENES, P53; GENES, TUMOR SUPPRESSOR; HEAD AND NECK NEOPLASMS; HUMANS; INDEL MUTATION; MUTATION; MUTATION, MISSENSE; NEOPLASMS, SQUAMOUS CELL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; ONCOGENES; PAPILLOMAVIRIDAE; PAPILLOMAVIRUS INFECTIONS; RECEPTOR, NOTCH1; SEQUENCE ANALYSIS, DNA; SMOKING; TOBACCO; UBIQUITIN-PROTEIN LIGASES;

HUMAN PAPILLOMAVIRUS; NICOTIANA TABACUM;

EID: 80052177544     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1206923     Document Type: Article

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