The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia

Journal of Experimental Medicine

Volumn 204, Issue 8, 2007, Pages 1825-1835

  Thompson, Benjamin J ^a,b   Buonamici, Silvia ^a   Sulis, Maria Luisa ^c   Palomero, Teresa ^c   Vilimas, Tomas ^d   Basso, Giuseppe ^e   Ferrando, Adolfo ^c   Aifantis, Iannis ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c Och Spine at New York Presbyterian Hospitals   (United States)

^d NORTHWESTERN UNIVERSITY   (United States)

^e UNIVERSITY OF PADOVA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CYCLIN E; GAMMA SECRETASE INHIBITOR; MYC PROTEIN; UBIQUITIN PROTEIN LIGASE; CELL CYCLE PROTEIN; F BOX PROTEIN; FBXW7 PROTEIN, HUMAN; NOTCH1 PROTEIN, HUMAN; NOTCH1 RECEPTOR; SECRETASE; STEM CELL FACTOR; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; ENZYME DEGRADATION; GENE MUTATION; GENE TARGETING; HUMAN; HUMAN CELL; LEUKEMIA; NUCLEOTIDE SEQUENCE; ONCOGENE C MYC; PRIORITY JOURNAL; RELAPSE; T CELL LEUKEMIA; TUMOR SUPPRESSOR GENE; UBIQUITINATION; ACUTE LYMPHOCYTIC LEUKEMIA; BIOSYNTHESIS; DRUG ANTAGONISM; ENZYMOLOGY; FLUORESCENCE MICROSCOPY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MUTATION; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE;

AMYLOID PRECURSOR PROTEIN SECRETASES; CELL CYCLE PROTEINS; F-BOX PROTEINS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, TUMOR SUPPRESSOR; HUMANS; LEUKEMIA, LYMPHOCYTIC, ACUTE; LEUKEMIA, T-CELL; MICROSCOPY, FLUORESCENCE; MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS C-MYC; RECEPTOR, NOTCH1; STEM CELL FACTOR; UBIQUITIN-PROTEIN LIGASES;

EID: 34547820257     PISSN: 00221007     EISSN: 00221007     Source Type: Journal    
DOI: 10.1084/jem.20070872     Document Type: Article

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