Activated Notch1 induces lung adenomas in mice and cooperates with Myc in the generation of lung adenocarcinoma

Cancer Research

Volumn 71, Issue 18, 2011, Pages 6010-6018

  Allen, Thaddeus D ^a   Rodriguez, Elena M ^a   Jones, Kirk D ^a   Bishop, J Michael ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MYC PROTEIN; MYCL1 PROTEIN; NOTCH1 RECEPTOR; PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CARCINOGENESIS; CARCINOGENICITY; CELL CYCLE; CONTROLLED STUDY; DRUG TARGETING; LUNG ADENOCARCINOMA; LUNG ADENOMA; LUNG ALVEOLUS EPITHELIUM; MALIGNANT TRANSFORMATION; METASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSGENIC MOUSE; TUMOR CELL; TUMOR GROWTH;

ADENOCARCINOMA; ADENOMA; ANIMALS; APOPTOSIS; CELL TRANSFORMATION, NEOPLASTIC; GENES, MYC; HUMANS; HYPERPLASIA; LUNG NEOPLASMS; MICE; MICE, TRANSGENIC; PROTO-ONCOGENE PROTEINS C-BCL-2; PROTO-ONCOGENE PROTEINS C-MDM2; PROTO-ONCOGENE PROTEINS C-MYC; PROTO-ONCOGENE PROTEINS P21(RAS); PULMONARY ALVEOLI; RECEPTOR, NOTCH1; TRANSGENES; TUMOR SUPPRESSOR PROTEIN P14ARF;

EID: 80052795864     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-11-0595     Document Type: Article

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