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Volumn 34, Issue 1, 2013, Pages 33-58

Molecular and cellular analysis of human histamine receptor subtypes

Author keywords

[No Author keywords available]

Indexed keywords

AMTHAMINE; ARPROMIDINE; BETAHISTINE; CLOZAPINE; DIMAPRIT; FAMOTIDINE; G PROTEIN COUPLED RECEPTOR; HISTAMINE; HISTAMINE H1 RECEPTOR; HISTAMINE H1 RECEPTOR ANTAGONIST; HISTAMINE H2 RECEPTOR; HISTAMINE H2 RECEPTOR ANTAGONIST; HISTAMINE H3 RECEPTOR; HISTAMINE H4 RECEPTOR; HISTAMINE H4 RECEPTOR ANTAGONIST; HISTAMINE RECEPTOR; HISTAMINERGIC RECEPTOR AFFECTING AGENT; HISTAPRODIFEN; IMETIT; IMPROMIDINE; INTERLEUKIN 2; LIGAND; LOXAPINE; MEPYRAMINE; PITOLISANT; PROTON PUMP INHIBITOR; RECEPTOR ANTIBODY; RECEPTOR SUBTYPE; THIOPERAMIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 84871743467     PISSN: 01656147     EISSN: 18733735     Source Type: Journal    
DOI: 10.1016/j.tips.2012.11.001     Document Type: Review
Times cited : (139)

References (217)
  • 2
    • 83555173617 scopus 로고    scopus 로고
    • Urticaria and its subtypes: The role of the second-generation antihistamines
    • J.P. Ortonne Urticaria and its subtypes: the role of the second-generation antihistamines Eur. J. Intern. Med. 23 2012 26 30
    • (2012) Eur. J. Intern. Med. , vol.23 , pp. 26-30
    • Ortonne, J.P.1
  • 5
    • 23844527126 scopus 로고    scopus 로고
    • Antihistamines in dermatology
    • M.W. Greaves Antihistamines in dermatology Skin Pharmacol. Physiol. 18 2005 220 229
    • (2005) Skin Pharmacol. Physiol. , vol.18 , pp. 220-229
    • Greaves, M.W.1
  • 6
    • 77649214612 scopus 로고    scopus 로고
    • 2LEN position paper
    • 2LEN position paper Allergy 65 2010 459 466
    • (2010) Allergy , vol.65 , pp. 459-466
    • Church, M.K.1
  • 7
    • 33845924770 scopus 로고    scopus 로고
    • 4 receptor antagonists are superior to traditional antihistamines in the attenuation of experimental pruritus
    • 4 receptor antagonists are superior to traditional antihistamines in the attenuation of experimental pruritus J. Allergy Clin. Immunol. 119 2007 176 183
    • (2007) J. Allergy Clin. Immunol. , vol.119 , pp. 176-183
    • Dunford, P.J.1
  • 8
    • 79958026433 scopus 로고    scopus 로고
    • 3 receptor: From discovery to clinical trials with pitolisant
    • 3 receptor: from discovery to clinical trials with pitolisant Br. J. Pharmacol. 163 2011 713 721
    • (2011) Br. J. Pharmacol. , vol.163 , pp. 713-721
    • Schwartz, J.C.1
  • 9
    • 79954426466 scopus 로고    scopus 로고
    • The scientific legacy of Sir James W. Black
    • C.P. Page The scientific legacy of Sir James W. Black Trends Pharmacol. Sci. 32 2011 181 182
    • (2011) Trends Pharmacol. Sci. , vol.32 , pp. 181-182
    • Page, C.P.1
  • 10
    • 79954418654 scopus 로고    scopus 로고
    • Pharmacological management of GERD: Where does it stand now?
    • T. Hershcovici, and R. Fass Pharmacological management of GERD: where does it stand now? Trends Pharmacol. Sci. 32 2011 258 264
    • (2011) Trends Pharmacol. Sci. , vol.32 , pp. 258-264
    • Hershcovici, T.1    Fass, R.2
  • 12
    • 0025195207 scopus 로고
    • 2-receptors involved in the regulation of NADPH oxidase?
    • 2-receptors involved in the regulation of NADPH oxidase? Naunyn Schmiedebergs Arch. Pharmacol. 341 1990 455 461
    • (1990) Naunyn Schmiedebergs Arch. Pharmacol. , vol.341 , pp. 455-461
    • Burde, R.1
  • 13
    • 84870471262 scopus 로고    scopus 로고
    • 2 receptors expressed by leukemic cells
    • 2 receptors expressed by leukemic cells Haematologica 97 2012 1904 1908
    • (2012) Haematologica , vol.97 , pp. 1904-1908
    • Aurelius, J.1
  • 14
    • 78650959436 scopus 로고    scopus 로고
    • Histamine dihydrochloride in the management of acute myeloid leukaemia
    • L.P. Yang, and C.M. Perry Histamine dihydrochloride in the management of acute myeloid leukaemia Drugs 71 2011 109 122
    • (2011) Drugs , vol.71 , pp. 109-122
    • Yang, L.P.1    Perry, C.M.2
  • 15
    • 0028945786 scopus 로고
    • 2-receptor agonists in congestive heart failure
    • 2-receptor agonists in congestive heart failure Eur. J. Clin. Invest. 25 Suppl. 1 1995 42 46
    • (1995) Eur. J. Clin. Invest. , vol.25 , Issue.SUPPL. 1 , pp. 42-46
    • Felix, S.B.1
  • 17
    • 50349091819 scopus 로고    scopus 로고
    • Histamine in the nervous system
    • H.L. Haas Histamine in the nervous system Physiol. Rev. 88 2008 1183 1241
    • (2008) Physiol. Rev. , vol.88 , pp. 1183-1241
    • Haas, H.L.1
  • 18
    • 37749048627 scopus 로고    scopus 로고
    • 4 receptors in allergic inflammation: The search for new antihistamines
    • 4 receptors in allergic inflammation: the search for new antihistamines Nat. Rev. Drug Discov. 7 2008 41 53
    • (2008) Nat. Rev. Drug Discov. , vol.7 , pp. 41-53
    • Thurmond, R.L.1
  • 20
    • 79954420065 scopus 로고    scopus 로고
    • En route to new blockbuster anti-histamines: Surveying the offspring of the expanding histamine receptor family
    • R. Leurs En route to new blockbuster anti-histamines: surveying the offspring of the expanding histamine receptor family Trends Pharmacol. Sci. 32 2011 250 257
    • (2011) Trends Pharmacol. Sci. , vol.32 , pp. 250-257
    • Leurs, R.1
  • 21
    • 80053118965 scopus 로고    scopus 로고
    • 4 receptor in inflammatory skin diseases and pruritus
    • 4 receptor in inflammatory skin diseases and pruritus Front. Biosci. (Schol. Ed.) 3 2011 985 994
    • (2011) Front. Biosci. (Schol. Ed.) , vol.3 , pp. 985-994
    • Gutzmer, R.1
  • 22
    • 84858736646 scopus 로고    scopus 로고
    • 4 receptor ligands and their potential therapeutic applications: An update
    • 4 receptor ligands and their potential therapeutic applications: an update Expert Opin. Ther. Pat. 22 2012 205 221
    • (2012) Expert Opin. Ther. Pat. , vol.22 , pp. 205-221
    • Kiss, R.1    Keserü, G.M.2
  • 23
    • 84871788150 scopus 로고    scopus 로고
    • Species-dependent activities of G-protein-coupled receptor ligands: Lessons from histamine receptor orthologs
    • doi:10.1016/j.tips.2012.10.004 (in press)
    • Strasser, A. et al. (2013). Species-dependent activities of G-protein-coupled receptor ligands: lessons from histamine receptor orthologs. Trends Pharmacol. Sci., http://dx.doi.org/10.1016/j.tips.2012.10.004 (in press)
    • (2013) Trends Pharmacol. Sci.
    • Strasser, A.1
  • 24
    • 72449183606 scopus 로고    scopus 로고
    • Histamine, histamine receptors and their role in immune pathology
    • M. Jutel Histamine, histamine receptors and their role in immune pathology Clin. Exp. Allergy 39 2009 1786 1800
    • (2009) Clin. Exp. Allergy , vol.39 , pp. 1786-1800
    • Jutel, M.1
  • 25
    • 0027065040 scopus 로고
    • 1 receptors and is an incomplete secretagogue
    • 1 receptors and is an incomplete secretagogue Mol. Pharmacol. 42 1992 227 234
    • (1992) Mol. Pharmacol. , vol.42 , pp. 227-234
    • Seifert, R.1
  • 27
    • 0028182722 scopus 로고
    • i proteins in HL-60 cells through a mechanism that is independent of known histamine receptor subtypes
    • i proteins in HL-60 cells through a mechanism that is independent of known histamine receptor subtypes Mol. Pharmacol. 45 1994 578 586
    • (1994) Mol. Pharmacol. , vol.45 , pp. 578-586
    • Seifert, R.1
  • 29
    • 0141841768 scopus 로고    scopus 로고
    • Partial agonist behaviour depends upon the level of nociceptin/orphanin FQ receptor expression: Studies using the ecdysone-inducible mammalian expression system
    • J. McDonald Partial agonist behaviour depends upon the level of nociceptin/orphanin FQ receptor expression: studies using the ecdysone-inducible mammalian expression system Br. J. Pharmacol. 140 2003 61 70
    • (2003) Br. J. Pharmacol. , vol.140 , pp. 61-70
    • McDonald, J.1
  • 30
    • 34447642715 scopus 로고    scopus 로고
    • The evasive nature of drug efficacy: Implications for drug discovery
    • S. Galandrin The evasive nature of drug efficacy: implications for drug discovery Trends Pharmacol. Sci. 28 2007 423 430
    • (2007) Trends Pharmacol. Sci. , vol.28 , pp. 423-430
    • Galandrin, S.1
  • 31
    • 84857497773 scopus 로고    scopus 로고
    • Biased signalling and allosteric machines: New vistas and challenges for drug discovery
    • T.P. Kenakin Biased signalling and allosteric machines: new vistas and challenges for drug discovery Br. J. Pharmacol. 165 2012 1659 1669
    • (2012) Br. J. Pharmacol. , vol.165 , pp. 1659-1669
    • Kenakin, T.P.1
  • 32
    • 84866610509 scopus 로고    scopus 로고
    • 2-receptor in human eosinophils and neutrophils
    • 2-receptor in human eosinophils and neutrophils Biochem. Pharmacol. 84 2012 1174 1185
    • (2012) Biochem. Pharmacol. , vol.84 , pp. 1174-1185
    • Reher, T.M.1
  • 33
    • 84861229120 scopus 로고    scopus 로고
    • 4-receptor: Evidence for ligand-specific receptor conformations
    • 4-receptor: evidence for ligand-specific receptor conformations Biochem. Pharmacol. 84 2012 192 203
    • (2012) Biochem. Pharmacol. , vol.84 , pp. 192-203
    • Reher, T.M.1
  • 34
    • 0020059347 scopus 로고
    • Human polymorphonuclear neutrophils. Pharmacological characterization of histamine receptors mediating the elevation of cyclic AMP
    • C. Gespach, and J.P. Abita Human polymorphonuclear neutrophils. Pharmacological characterization of histamine receptors mediating the elevation of cyclic AMP Mol. Pharmacol. 21 1982 78 85
    • (1982) Mol. Pharmacol. , vol.21 , pp. 78-85
    • Gespach, C.1    Abita, J.P.2
  • 35
    • 0020395599 scopus 로고
    • Identification and characterization of surface receptors for histamine in the human promyelocytic leukemia cell line HL-60. Comparison with human peripheral neutrophils
    • C. Gespach Identification and characterization of surface receptors for histamine in the human promyelocytic leukemia cell line HL-60. Comparison with human peripheral neutrophils Mol. Pharmacol. 22 1982 547 553
    • (1982) Mol. Pharmacol. , vol.22 , pp. 547-553
    • Gespach, C.1
  • 36
    • 0027065041 scopus 로고
    • 2 receptors with an unique agonist/antagonist profile and induces functional differentiation
    • 2 receptors with an unique agonist/antagonist profile and induces functional differentiation Mol. Pharmacol. 42 1992 235 241
    • (1992) Mol. Pharmacol. , vol.42 , pp. 235-241
    • Seifert, R.1
  • 37
    • 0021893413 scopus 로고
    • 2 receptor activity during differentiation of the human monocytic-like cell line U-937. Comparison with prostaglandins and isoproterenol
    • 2 receptor activity during differentiation of the human monocytic-like cell line U-937. Comparison with prostaglandins and isoproterenol FEBS Lett. 184 1985 207 213
    • (1985) FEBS Lett. , vol.184 , pp. 207-213
    • Gespach, C.1
  • 38
    • 33746238114 scopus 로고    scopus 로고
    • 2 histamine receptor signaling
    • 2 histamine receptor signaling Mol. Pharmacol. 70 2006 493 500
    • (2006) Mol. Pharmacol. , vol.70 , pp. 493-500
    • Kim, D.C.1
  • 39
    • 0042343718 scopus 로고    scopus 로고
    • 2 receptor inverse agonist that binds with high affinity to an inactive G-protein-coupled form of the receptor. Experimental support for the cubic ternary complex model
    • 2 receptor inverse agonist that binds with high affinity to an inactive G-protein-coupled form of the receptor. Experimental support for the cubic ternary complex model Mol. Pharmacol. 64 2003 512 520
    • (2003) Mol. Pharmacol. , vol.64 , pp. 512-520
    • Monczor, F.1
  • 41
    • 0030914524 scopus 로고    scopus 로고
    • 2 receptor in the human promonocytic cell line U937
    • 2 receptor in the human promonocytic cell line U937 Mol. Pharmacol. 51 1997 983 990
    • (1997) Mol. Pharmacol. , vol.51 , pp. 983-990
    • Shayo, C.1
  • 42
    • 79953191123 scopus 로고    scopus 로고
    • Multidrug resistance protein 4 (MRP4/ABCC4) regulates cAMP cellular levels and controls human leukemia cell proliferation and differentiation
    • S. Copsel Multidrug resistance protein 4 (MRP4/ABCC4) regulates cAMP cellular levels and controls human leukemia cell proliferation and differentiation J. Biol. Chem. 286 2011 6979 6988
    • (2011) J. Biol. Chem. , vol.286 , pp. 6979-6988
    • Copsel, S.1
  • 44
    • 57349083232 scopus 로고    scopus 로고
    • 3 receptor antagonists go to clinics
    • 3 receptor antagonists go to clinics Biol. Pharm. Bull. 31 2008 2163 2181
    • (2008) Biol. Pharm. Bull. , vol.31 , pp. 2163-2181
    • Sander, K.1
  • 45
    • 0036978843 scopus 로고    scopus 로고
    • 4 receptor on human eosinophils-role in eosinophil chemotaxis
    • 4 receptor on human eosinophils-role in eosinophil chemotaxis J. Recept. Signal Transduct. Res. 22 2002 431 448
    • (2002) J. Recept. Signal Transduct. Res. , vol.22 , pp. 431-448
    • O'Reilly, M.1
  • 46
    • 0028308210 scopus 로고
    • Pharmacologic characterization of a novel histamine receptor on human eosinophils
    • D.G. Raible Pharmacologic characterization of a novel histamine receptor on human eosinophils Am. J. Respir. Crit. Care Med. 149 1994 1506 1511
    • (1994) Am. J. Respir. Crit. Care Med. , vol.149 , pp. 1506-1511
    • Raible, D.G.1
  • 48
    • 2542530713 scopus 로고    scopus 로고
    • 4 receptor mediates eosinophil chemotaxis with cell shape change and adhesion molecule upregulation
    • 4 receptor mediates eosinophil chemotaxis with cell shape change and adhesion molecule upregulation Br. J. Pharmacol. 142 2004 161 171
    • (2004) Br. J. Pharmacol. , vol.142 , pp. 161-171
    • Ling, P.1
  • 50
    • 70350050831 scopus 로고    scopus 로고
    • 4 receptor agonists
    • 4 receptor agonists J. Med. Chem. 52 2009 6297 6313
    • (2009) J. Med. Chem. , vol.52 , pp. 6297-6313
    • Igel, P.1
  • 53
    • 84866743083 scopus 로고    scopus 로고
    • Well characterized antihistamine 4 receptor antibodies contribute to current knowledge of the expression and biology of the human and murine histamine 4 receptor
    • R. Gutzmer Well characterized antihistamine 4 receptor antibodies contribute to current knowledge of the expression and biology of the human and murine histamine 4 receptor Naunyn Schmiedebergs Arch. Pharmacol. 385 2012 853 854
    • (2012) Naunyn Schmiedebergs Arch. Pharmacol. , vol.385 , pp. 853-854
    • Gutzmer, R.1
  • 56
    • 79953019023 scopus 로고    scopus 로고
    • 4 receptor joins the club of 7 transmembrane domain receptors exhibiting functional selectivity
    • 4 receptor joins the club of 7 transmembrane domain receptors exhibiting functional selectivity Mol. Pharmacol. 79 2011 631 638
    • (2011) Mol. Pharmacol. , vol.79 , pp. 631-638
    • Seifert, R.1
  • 58
    • 0028246623 scopus 로고
    • 2 receptor stably expressed in Chinese hamster ovary cells
    • 2 receptor stably expressed in Chinese hamster ovary cells Br. J. Pharmacol. 112 1994 847 854
    • (1994) Br. J. Pharmacol. , vol.112 , pp. 847-854
    • Leurs, R.1
  • 59
    • 0035120049 scopus 로고    scopus 로고
    • Cloning and characterization of a novel human histamine receptor
    • K.L. Morse Cloning and characterization of a novel human histamine receptor J. Pharmacol. Exp. Ther. 296 2001 1058 1066
    • (2001) J. Pharmacol. Exp. Ther. , vol.296 , pp. 1058-1066
    • Morse, K.L.1
  • 61
    • 80051697652 scopus 로고    scopus 로고
    • 2 receptor by G protein-coupled receptor kinase 2
    • 2 receptor by G protein-coupled receptor kinase 2 J. Biol. Chem. 286 2011 28697 28706
    • (2011) J. Biol. Chem. , vol.286 , pp. 28697-28706
    • Fernandez, N.1
  • 62
    • 12144288036 scopus 로고    scopus 로고
    • 4 receptor antagonist with anti-inflammatory properties
    • 4 receptor antagonist with anti-inflammatory properties J. Pharmacol. Exp. Ther. 309 2004 404 413
    • (2004) J. Pharmacol. Exp. Ther. , vol.309 , pp. 404-413
    • Thurmond, R.L.1
  • 63
    • 0034752736 scopus 로고    scopus 로고
    • q/11-subunits in constitutive and agonist-mediated signaling
    • q/11-subunits in constitutive and agonist-mediated signaling Mol. Pharmacol. 60 2001 1133 1142
    • (2001) Mol. Pharmacol. , vol.60 , pp. 1133-1142
    • Bakker, R.A.1
  • 67
    • 0036033424 scopus 로고    scopus 로고
    • Constitutive activity of G-protein-coupled receptors: Cause of disease and common property of wild-type receptors
    • R. Seifert, and K. Wenzel-Seifert Constitutive activity of G-protein-coupled receptors: cause of disease and common property of wild-type receptors Naunyn Schmiedebergs Arch. Pharmacol. 366 2002 381 416
    • (2002) Naunyn Schmiedebergs Arch. Pharmacol. , vol.366 , pp. 381-416
    • Seifert, R.1    Wenzel-Seifert, K.2
  • 68
    • 0032527117 scopus 로고    scopus 로고
    • sα fusion protein
    • sα fusion protein Eur. J. Biochem. 255 1998 369 382
    • (1998) Eur. J. Biochem. , vol.255 , pp. 369-382
    • Seifert, R.1
  • 70
    • 0034711258 scopus 로고    scopus 로고
    • Molecular cloning and characterization of a novel type of histamine receptor preferentially expressed in leukocytes
    • T. Oda Molecular cloning and characterization of a novel type of histamine receptor preferentially expressed in leukocytes J. Biol. Chem. 275 2000 36781 36786
    • (2000) J. Biol. Chem. , vol.275 , pp. 36781-36786
    • Oda, T.1
  • 71
    • 79953006585 scopus 로고    scopus 로고
    • 4 receptor: JNJ7777120 recruits β-arrestin without activating G proteins
    • 4 receptor: JNJ7777120 recruits β-arrestin without activating G proteins Mol. Pharmacol. 79 2011 749 757
    • (2011) Mol. Pharmacol. , vol.79 , pp. 749-757
    • Rosethorne, E.M.1    Charlton, S.J.2
  • 72
    • 77951844975 scopus 로고    scopus 로고
    • Teaching old receptors new tricks: Biasing seven-transmembrane receptors
    • S. Rajagopal Teaching old receptors new tricks: biasing seven-transmembrane receptors Nat. Rev. Drug Discov. 9 2010 373 386
    • (2010) Nat. Rev. Drug Discov. , vol.9 , pp. 373-386
    • Rajagopal, S.1
  • 73
    • 0036021470 scopus 로고    scopus 로고
    • q-protein coupling
    • q-protein coupling J. Neurochem. 80 2002 678 696
    • (2002) J. Neurochem. , vol.80 , pp. 678-696
    • Houston, C.1
  • 74
    • 0035210712 scopus 로고    scopus 로고
    • 2-receptor with guanidine-type agonists
    • 2-receptor with guanidine-type agonists Mol. Pharmacol. 60 2001 1210 1215
    • (2001) Mol. Pharmacol. , vol.60 , pp. 1210-1215
    • Kelley, M.T.1
  • 77
    • 0024327023 scopus 로고
    • Synthesis and in vitro pharmacology of arpromidine and related phenyl(pyridylalkyl)guanidines, a potential new class of positive inotropic drugs
    • A. Buschauer Synthesis and in vitro pharmacology of arpromidine and related phenyl(pyridylalkyl)guanidines, a potential new class of positive inotropic drugs J. Med. Chem. 32 1989 1963 1970
    • (1989) J. Med. Chem. , vol.32 , pp. 1963-1970
    • Buschauer, A.1
  • 78
    • 56749180999 scopus 로고    scopus 로고
    • 2 receptor agonists
    • 2 receptor agonists J. Med. Chem. 51 2008 7193 7204
    • (2008) J. Med. Chem. , vol.51 , pp. 7193-7204
    • Ghorai, P.1
  • 79
    • 33645114357 scopus 로고    scopus 로고
    • G-acylated imidazolylpropylguanidines
    • G-acylated imidazolylpropylguanidines J. Pharmacol. Exp. Ther. 317 2006 139 146
    • (2006) J. Pharmacol. Exp. Ther. , vol.317 , pp. 139-146
    • Xie, S.X.1
  • 81
    • 65249091015 scopus 로고    scopus 로고
    • G-substituent
    • G-substituent J. Med. Chem. 52 2009 2623 2627
    • (2009) J. Med. Chem. , vol.52 , pp. 2623-2627
    • Igel, P.1
  • 82
    • 0028986019 scopus 로고
    • 1 receptor agonist activity of a series of 2-phenylhistamines, 2-heteroarylhistamines, and analogues
    • 1 receptor agonist activity of a series of 2-phenylhistamines, 2-heteroarylhistamines, and analogues J. Med. Chem. 38 1995 1287 1294
    • (1995) J. Med. Chem. , vol.38 , pp. 1287-1294
    • Leschke, C.1
  • 83
    • 0034704819 scopus 로고    scopus 로고
    • 1-receptor agonists
    • 1-receptor agonists J. Med. Chem. 43 2000 1071 1084
    • (2000) J. Med. Chem. , vol.43 , pp. 1071-1084
    • Elz, S.1
  • 85
    • 0035119027 scopus 로고    scopus 로고
    • Genomics meets histamine receptors: New subtypes, new receptors
    • L.B. Hough Genomics meets histamine receptors: new subtypes, new receptors Mol. Pharmacol. 59 2001 415 419
    • (2001) Mol. Pharmacol. , vol.59 , pp. 415-419
    • Hough, L.B.1
  • 86
    • 0015518297 scopus 로고
    • 2-receptors
    • 2-receptors Nature 236 1972 385 390
    • (1972) Nature , vol.236 , pp. 385-390
    • Black, J.W.1
  • 88
    • 84865322363 scopus 로고    scopus 로고
    • Clozapine for the treatment of schizophrenia
    • E. Fakra, and J.M. Azorin Clozapine for the treatment of schizophrenia Expert Opin. Pharmacother. 13 2012 1923 1935
    • (2012) Expert Opin. Pharmacother. , vol.13 , pp. 1923-1935
    • Fakra, E.1    Azorin, J.M.2
  • 89
    • 84857030583 scopus 로고    scopus 로고
    • 4R receptors with 34 antidepressants and antipsychotics
    • 4R receptors with 34 antidepressants and antipsychotics Naunyn Schmiedebergs Arch. Pharmacol. 385 2012 145 170
    • (2012) Naunyn Schmiedebergs Arch. Pharmacol. , vol.385 , pp. 145-170
    • Appl, H.1
  • 90
    • 72149090641 scopus 로고    scopus 로고
    • Metabolic side effects of antipsychotic drug treatment-pharmacological mechanisms
    • G.P. Reynolds, and S.L. Kirk Metabolic side effects of antipsychotic drug treatment-pharmacological mechanisms Pharmacol. Ther. 125 2010 169 179
    • (2010) Pharmacol. Ther. , vol.125 , pp. 169-179
    • Reynolds, G.P.1    Kirk, S.L.2
  • 91
    • 79956259714 scopus 로고    scopus 로고
    • Haematological toxicity of clozapine and some other drugs used in psychiatry
    • P.M. Nooijen Haematological toxicity of clozapine and some other drugs used in psychiatry Hum. Psychopharmacol. 26 2011 112 119
    • (2011) Hum. Psychopharmacol. , vol.26 , pp. 112-119
    • Nooijen, P.M.1
  • 92
    • 77951033264 scopus 로고    scopus 로고
    • 4R species variants
    • 4R species variants Mol. Pharmacol. 77 2010 734 743
    • (2010) Mol. Pharmacol. , vol.77 , pp. 734-743
    • Lim, H.D.1
  • 93
    • 0030254780 scopus 로고    scopus 로고
    • 2 receptor. I. Theoretical investigations of histamine binding to an oligopeptide mimicking a part of the fifth transmembrane α-helix
    • 2 receptor. I. Theoretical investigations of histamine binding to an oligopeptide mimicking a part of the fifth transmembrane α-helix J. Comput. Aided Mol. Des. 10 1996 461 478
    • (1996) J. Comput. Aided Mol. Des. , vol.10 , pp. 461-478
    • Nederkoorn, P.H.1
  • 94
    • 47349116596 scopus 로고    scopus 로고
    • 4 receptor-an explicit membrane molecular dynamics simulation study
    • 4 receptor-an explicit membrane molecular dynamics simulation study J. Chem. Inf. Model. 48 2008 1199 1210
    • (2008) J. Chem. Inf. Model. , vol.48 , pp. 1199-1210
    • Jójárt, B.1
  • 95
    • 0345490945 scopus 로고    scopus 로고
    • International Union of Pharmacology Committee on Receptor Nomenclature and Drug Classification: XXXVIII. Update on terms and symbols in quantitative pharmacology
    • R.R. Neubig International Union of Pharmacology Committee on Receptor Nomenclature and Drug Classification: XXXVIII. Update on terms and symbols in quantitative pharmacology Pharmacol. Rev. 55 2003 597 606
    • (2003) Pharmacol. Rev. , vol.55 , pp. 597-606
    • Neubig, R.R.1
  • 97
    • 84869825728 scopus 로고    scopus 로고
    • i and β-arrestin2 biased ligands
    • i and β-arrestin2 biased ligands Mol. Pharmacol. 82 2012 1174 1182
    • (2012) Mol. Pharmacol. , vol.82 , pp. 1174-1182
    • Nijmeijer, S.1
  • 98
    • 77349123734 scopus 로고    scopus 로고
    • 3 receptor function by monovalent ions
    • 3 receptor function by monovalent ions Neurosci. Lett. 472 2010 114 118
    • (2010) Neurosci. Lett. , vol.472 , pp. 114-118
    • Schnell, D.1    Seifert, R.2
  • 99
    • 84861961427 scopus 로고    scopus 로고
    • Structural basis for allosteric regulation of GPCRs by sodium ions
    • W. Liu Structural basis for allosteric regulation of GPCRs by sodium ions Science 337 2012 232 236
    • (2012) Science , vol.337 , pp. 232-236
    • Liu, W.1
  • 100
    • 50349086333 scopus 로고    scopus 로고
    • Neuropharmacology of second-generation antipsychotic drugs: A validity of the serotonin-dopamine hypothesis
    • T. Kuroki Neuropharmacology of second-generation antipsychotic drugs: a validity of the serotonin-dopamine hypothesis Prog. Brain Res. 172 2008 199 212
    • (2008) Prog. Brain Res. , vol.172 , pp. 199-212
    • Kuroki, T.1
  • 101
    • 54049141721 scopus 로고    scopus 로고
    • Antipsychotic drugs: Comparison in animal models of efficacy, neurotransmitter regulation, and neuroprotection
    • J.A. Lieberman Antipsychotic drugs: comparison in animal models of efficacy, neurotransmitter regulation, and neuroprotection Pharmacol. Rev. 60 2008 358 403
    • (2008) Pharmacol. Rev. , vol.60 , pp. 358-403
    • Lieberman, J.A.1
  • 103
  • 104
    • 0032723296 scopus 로고    scopus 로고
    • 1-histamine receptor antagonists in fluorescent imaging plate reader-based calcium assays
    • 1-histamine receptor antagonists in fluorescent imaging plate reader-based calcium assays J. Biomol. Screen. 4 1999 249 258
    • (1999) J. Biomol. Screen. , vol.4 , pp. 249-258
    • Miller, T.R.1
  • 105
    • 0346732300 scopus 로고    scopus 로고
    • Activation of the canonical β-catenin pathway by histamine
    • S.H. Diks Activation of the canonical β-catenin pathway by histamine J. Biol. Chem. 278 2003 52491 52496
    • (2003) J. Biol. Chem. , vol.278 , pp. 52491-52496
    • Diks, S.H.1
  • 106
    • 34247374828 scopus 로고    scopus 로고
    • 1 receptor itself through activation of receptor gene transcription
    • 1 receptor itself through activation of receptor gene transcription J. Pharmacol. Sci. 103 2007 374 382
    • (2007) J. Pharmacol. Sci. , vol.103 , pp. 374-382
    • Das, A.K.1
  • 107
    • 80052248531 scopus 로고    scopus 로고
    • 1 receptor gene expression in HeLa cells
    • 1 receptor gene expression in HeLa cells J. Biol. Chem. 286 2011 30542 30551
    • (2011) J. Biol. Chem. , vol.286 , pp. 30542-30551
    • Mizuguchi, H.1
  • 108
    • 0026733146 scopus 로고
    • 1 receptor in human HeLa cells: Involvement of protein kinase C dependent and independent pathways
    • 1 receptor in human HeLa cells: involvement of protein kinase C dependent and independent pathways Br. J. Pharmacol. 107 1992 448 455
    • (1992) Br. J. Pharmacol. , vol.107 , pp. 448-455
    • Smit, M.J.1
  • 109
    • 0031597434 scopus 로고    scopus 로고
    • 1 receptors in human U373 MG astrocytoma cells
    • 1 receptors in human U373 MG astrocytoma cells J. Neurochem. 71 1998 2626 2633
    • (1998) J. Neurochem. , vol.71 , pp. 2626-2633
    • Hishinuma, S.1
  • 110
    • 0033938665 scopus 로고    scopus 로고
    • 2+-dependent inhibition of cyclic AMP accumulation by histamine and thapsigargin in human U373 MG astrocytoma cells
    • 2+-dependent inhibition of cyclic AMP accumulation by histamine and thapsigargin in human U373 MG astrocytoma cells Br. J. Pharmacol. 130 2000 1021 1030
    • (2000) Br. J. Pharmacol. , vol.130 , pp. 1021-1030
    • Wong, M.P.1
  • 111
    • 0028268573 scopus 로고
    • Calcium-dependence of histamine- and carbachol-induced inositol phosphate formation in human U373 MG astrocytoma cells: Comparison with HeLa cells and brain slices
    • J.A. Aria-Montaño Calcium-dependence of histamine- and carbachol-induced inositol phosphate formation in human U373 MG astrocytoma cells: comparison with HeLa cells and brain slices Br. J. Pharmacol. 111 1994 598 608
    • (1994) Br. J. Pharmacol. , vol.111 , pp. 598-608
    • Aria-Montaño, J.A.1
  • 112
    • 44349188062 scopus 로고    scopus 로고
    • 1-receptor antagonists based on receptor internalization
    • 1-receptor antagonists based on receptor internalization J. Pharmacol. Sci. 107 2008 66 79
    • (2008) J. Pharmacol. Sci. , vol.107 , pp. 66-79
    • Hishinuma, S.1
  • 113
    • 84864496050 scopus 로고    scopus 로고
    • 1-receptors is predominantly regulated by their internalization in human astrocytoma cells
    • 1-receptors is predominantly regulated by their internalization in human astrocytoma cells J. Pharmacol. Sci. 119 2012 233 242
    • (2012) J. Pharmacol. Sci. , vol.119 , pp. 233-242
    • Hishinuma, S.1
  • 114
    • 0035544049 scopus 로고    scopus 로고
    • 1 receptor activation stimulates mitogenesis in human astrocytoma U373 MG cells
    • 1 receptor activation stimulates mitogenesis in human astrocytoma U373 MG cells J. Neurooncol. 55 2001 81 89
    • (2001) J. Neurooncol. , vol.55 , pp. 81-89
    • Hernández-Angeles, A.1
  • 115
    • 79952536118 scopus 로고    scopus 로고
    • 1 receptor expression and enhances histamine responsiveness in human coronary artery endothelial cells
    • 1 receptor expression and enhances histamine responsiveness in human coronary artery endothelial cells Immunology 132 2011 578 588
    • (2011) Immunology , vol.132 , pp. 578-588
    • Raveendran, V.V.1
  • 116
    • 84861175227 scopus 로고    scopus 로고
    • 1 receptor in airway epithelial cells
    • 1 receptor in airway epithelial cells Acta Otolaryngol. 132 Suppl. 1 2012 S37 S43
    • (2012) Acta Otolaryngol. , vol.132 , Issue.SUPPL. 1
    • Kim, H.M.1
  • 117
    • 84884211475 scopus 로고    scopus 로고
    • 1 receptor expression in oral squamous cell carcinoma
    • 10.1007/s00784-012-0784-3
    • 1 receptor expression in oral squamous cell carcinoma Clin. Oral Investig. 2012 10.1007/s00784-012- 0784-3
    • (2012) Clin. Oral Investig.
    • Grimm, M.1
  • 118
    • 84859293539 scopus 로고    scopus 로고
    • Histamine reduces susceptibility to natural killer cells via down-regulation of NKG2D ligands on human monocytic leukaemia THP-1 cells
    • Y. Nagai Histamine reduces susceptibility to natural killer cells via down-regulation of NKG2D ligands on human monocytic leukaemia THP-1 cells Immunology 136 2012 103 114
    • (2012) Immunology , vol.136 , pp. 103-114
    • Nagai, Y.1
  • 120
    • 0024414792 scopus 로고
    • 2+ mobilization pathway in human HL-60 promyelocytic leukemia cells
    • 2+ mobilization pathway in human HL-60 promyelocytic leukemia cells J. Biol. Chem. 264 1989 18356 18362
    • (1989) J. Biol. Chem. , vol.264 , pp. 18356-18362
    • Mitsuhashi, M.1
  • 121
    • 0029671227 scopus 로고    scopus 로고
    • 2+ influx in all-trans-retinoic acid-differentiated HL-60 cells independently of phospholipase C or adenylyl cyclase
    • 2+ influx in all-trans-retinoic acid-differentiated HL-60 cells independently of phospholipase C or adenylyl cyclase Naunyn Schmiedebergs Arch. Pharmacol. 353 1996 123 129
    • (1996) Naunyn Schmiedebergs Arch. Pharmacol. , vol.353 , pp. 123-129
    • Burde, R.1    Seifert, R.2
  • 122
    • 0021285262 scopus 로고
    • 2 receptor desensitization in HL-60 human promyelocytic leukemia cells
    • 2 receptor desensitization in HL-60 human promyelocytic leukemia cells J. Pharmacol. Exp. Ther. 231 1984 1 7
    • (1984) J. Pharmacol. Exp. Ther. , vol.231 , pp. 1-7
    • Sawutz, D.G.1
  • 123
    • 0036257312 scopus 로고    scopus 로고
    • Expression and function of histamine receptors in human monocyte-derived dendritic cells
    • M. Idzko Expression and function of histamine receptors in human monocyte-derived dendritic cells J. Allergy Clin. Immunol. 109 2002 839 846
    • (2002) J. Allergy Clin. Immunol. , vol.109 , pp. 839-846
    • Idzko, M.1
  • 124
    • 77950946683 scopus 로고    scopus 로고
    • Histamine induces Th2 activation through the histamine receptor 1 in house dust mite rhinitic but not asthmatic patients
    • K. Botturi Histamine induces Th2 activation through the histamine receptor 1 in house dust mite rhinitic but not asthmatic patients Clin. Exp. Allergy 40 2010 755 762
    • (2010) Clin. Exp. Allergy , vol.40 , pp. 755-762
    • Botturi, K.1
  • 125
    • 84856082907 scopus 로고    scopus 로고
    • Characterization and function of histamine receptors in human bone marrow stromal cells
    • K. Nemeth Characterization and function of histamine receptors in human bone marrow stromal cells Stem Cells 30 2012 222 231
    • (2012) Stem Cells , vol.30 , pp. 222-231
    • Nemeth, K.1
  • 126
    • 84855355028 scopus 로고    scopus 로고
    • 2R) are associated with complicated courses of sigmoid diverticulitis
    • 2R) are associated with complicated courses of sigmoid diverticulitis J. Gastrointest. Surg. 16 2012 173 182
    • (2012) J. Gastrointest. Surg. , vol.16 , pp. 173-182
    • Von Rahden, B.H.1
  • 127
    • 0020527193 scopus 로고
    • Histamine modulation of human neutrophil oxidative metabolism, locomotion, degranulation, and membrane potential changes
    • B.E. Seligmann Histamine modulation of human neutrophil oxidative metabolism, locomotion, degranulation, and membrane potential changes J. Immunol. 130 1983 1902 1909
    • (1983) J. Immunol. , vol.130 , pp. 1902-1909
    • Seligmann, B.E.1
  • 128
    • 0017706219 scopus 로고
    • 2 histamine response of granulocytes of asthmatic patients
    • 2 histamine response of granulocytes of asthmatic patients J. Clin. Invest. 59 1977 1080 1087
    • (1977) J. Clin. Invest. , vol.59 , pp. 1080-1087
    • Busse, W.W.1    Sosman, J.2
  • 129
    • 0017201419 scopus 로고
    • 2 histamine receptor response
    • 2 histamine receptor response Science 194 1976 737 738
    • (1976) Science , vol.194 , pp. 737-738
    • Busse, W.W.1    Sosman, J.2
  • 130
  • 131
    • 0027257155 scopus 로고
    • 2 receptors in peripheral blood mononuclear cells. Comparison with IL-1 receptor antagonist
    • 2 receptors in peripheral blood mononuclear cells. Comparison with IL-1 receptor antagonist J. Clin. Invest. 92 1993 281 287
    • (1993) J. Clin. Invest. , vol.92 , pp. 281-287
    • Vannier, E.1    Dinarello, C.A.2
  • 132
    • 0034659855 scopus 로고    scopus 로고
    • Histamine is a potent inducer of IL-18 and IFN-γ in human peripheral blood mononuclear cells
    • H. Kohka Histamine is a potent inducer of IL-18 and IFN-γ in human peripheral blood mononuclear cells J. Immunol. 164 2000 6640 6646
    • (2000) J. Immunol. , vol.164 , pp. 6640-6646
    • Kohka, H.1
  • 133
    • 0020619247 scopus 로고
    • 2 receptors in the human gastric cancer cell line HGT-1
    • 2 receptors in the human gastric cancer cell line HGT-1 Biochem. Biophys. Res. Commun. 116 1983 251 257
    • (1983) Biochem. Biophys. Res. Commun. , vol.116 , pp. 251-257
    • Menez, I.1
  • 134
    • 0027312528 scopus 로고
    • Protein kinase C inhibits cyclic adenosine monophosphate generation by histamine and truncated glucagon like peptide 1 in the human gastric cancer cell line HGT-1
    • P. McKenna Protein kinase C inhibits cyclic adenosine monophosphate generation by histamine and truncated glucagon like peptide 1 in the human gastric cancer cell line HGT-1 Gut 34 1993 953 957
    • (1993) Gut , vol.34 , pp. 953-957
    • McKenna, P.1
  • 135
    • 0022555520 scopus 로고
    • 2 receptor antagonists in the human gastric cancer cell line HGT-1. Structure-activity relationship of isocytosine-furan and imidazole derivatives related to cimetidine
    • 2 receptor antagonists in the human gastric cancer cell line HGT-1. Structure-activity relationship of isocytosine-furan and imidazole derivatives related to cimetidine Biochem. Pharmacol. 35 1986 1825 1834
    • (1986) Biochem. Pharmacol. , vol.35 , pp. 1825-1834
    • Emami, S.1    Gespach, C.2
  • 136
    • 0021646521 scopus 로고
    • 2 receptor-mediated adenylate cyclase activation in the human gastric cancer cell line HGT-1
    • 2 receptor-mediated adenylate cyclase activation in the human gastric cancer cell line HGT-1 FEBS Lett. 177 1984 227 230
    • (1984) FEBS Lett. , vol.177 , pp. 227-230
    • Prost, A.1
  • 138
    • 0026522959 scopus 로고
    • 2 and histamine activate human eosinophils
    • 2 and histamine activate human eosinophils J. Immunol. 148 1992 3536 3542
    • (1992) J. Immunol. , vol.148 , pp. 3536-3542
    • Raible, D.G.1
  • 140
    • 0033775707 scopus 로고    scopus 로고
    • 2 receptors mediate the inhibitory effect of histamine on human eosinophil degranulation
    • 2 receptors mediate the inhibitory effect of histamine on human eosinophil degranulation Br. J. Pharmacol. 131 2000 482 488
    • (2000) Br. J. Pharmacol. , vol.131 , pp. 482-488
    • Ezeamuzie, C.I.1    Philips, E.2
  • 141
    • 84862830134 scopus 로고    scopus 로고
    • 2+ entry in Th2 response induced by histamine in human monocyte-derived dendritic cells
    • 2+ entry in Th2 response induced by histamine in human monocyte-derived dendritic cells Int. Immunopharmacol. 12 2012 358 367
    • (2012) Int. Immunopharmacol. , vol.12 , pp. 358-367
    • Geng, S.1
  • 143
    • 17844385099 scopus 로고    scopus 로고
    • 4 receptor stimulation suppresses IL-12p70 production and mediates chemotaxis in human monocyte-derived dendritic cells
    • 4 receptor stimulation suppresses IL-12p70 production and mediates chemotaxis in human monocyte-derived dendritic cells J. Immunol. 174 2005 5224 5232
    • (2005) J. Immunol. , vol.174 , pp. 5224-5232
    • Gutzmer, R.1
  • 144
    • 38849102422 scopus 로고    scopus 로고
    • 4 histamine receptor in human natural killer cells, monocytes, and dendritic cells
    • 4 histamine receptor in human natural killer cells, monocytes, and dendritic cells J. Immunol. 179 2007 7907 7915
    • (2007) J. Immunol. , vol.179 , pp. 7907-7915
    • Damaj, B.B.1
  • 146
    • 79956282000 scopus 로고    scopus 로고
    • 4 in colorectal carcinomas: A potential influence on tumor growth and progression
    • 4 in colorectal carcinomas: a potential influence on tumor growth and progression BMC Cancer 11 2011 195
    • (2011) BMC Cancer , vol.11 , pp. 195
    • Fang, Z.1
  • 147
    • 68449086860 scopus 로고    scopus 로고
    • 4 histamine receptors mediate cell cycle arrest in growth factor-induced murine and human hematopoietic progenitor cells
    • 4 histamine receptors mediate cell cycle arrest in growth factor-induced murine and human hematopoietic progenitor cells PLoS ONE 4 2009 e6504
    • (2009) PLoS ONE , vol.4 , pp. 6504
    • Petit-Bertron, A.F.1
  • 148
    • 34247465454 scopus 로고    scopus 로고
    • 4 agonism in antigen-specific human T-cell responses
    • 4 agonism in antigen-specific human T-cell responses Immunology 121 2007 266 275
    • (2007) Immunology , vol.121 , pp. 266-275
    • Sugata, Y.1
  • 150
    • 60849113110 scopus 로고    scopus 로고
    • Suitability of muscarinic acetylcholine receptor antibodies for immunohistochemistry evaluated on tissue sections of receptor gene-deficient mice
    • G. Jositsch Suitability of muscarinic acetylcholine receptor antibodies for immunohistochemistry evaluated on tissue sections of receptor gene-deficient mice Naunyn Schmiedebergs Arch. Pharmacol. 379 2009 389 395
    • (2009) Naunyn Schmiedebergs Arch. Pharmacol. , vol.379 , pp. 389-395
    • Jositsch, G.1
  • 151
    • 60849088554 scopus 로고    scopus 로고
    • Lack of specificity of commercially available antisera against muscarinic and adrenergic receptors
    • W. Pradidarcheep Lack of specificity of commercially available antisera against muscarinic and adrenergic receptors Naunyn Schmiedebergs Arch. Pharmacol. 379 2009 397 402
    • (2009) Naunyn Schmiedebergs Arch. Pharmacol. , vol.379 , pp. 397-402
    • Pradidarcheep, W.1
  • 152
    • 60849130682 scopus 로고    scopus 로고
    • How reliable are G-protein-coupled receptor antibodies?
    • M.C. Michel How reliable are G-protein-coupled receptor antibodies? Naunyn Schmiedebergs Arch. Pharmacol. 379 2009 385 388
    • (2009) Naunyn Schmiedebergs Arch. Pharmacol. , vol.379 , pp. 385-388
    • Michel, M.C.1
  • 153
    • 0030069937 scopus 로고    scopus 로고
    • 1-receptor antagonists in HL-60 cells, basophils, and mast cells
    • 1-receptor antagonists in HL-60 cells, basophils, and mast cells Biochem. Pharmacol. 51 1996 125 131
    • (1996) Biochem. Pharmacol. , vol.51 , pp. 125-131
    • Burde, R.1
  • 154
    • 0028925781 scopus 로고
    • Histamine receptor-dependent and/or -independent activation of guanine nucleotide-binding proteins by histamine and 2-substituted histamine derivatives in human leukemia (HL-60) and human erythroleukemia (HEL) cells
    • A. Hagelüken Histamine receptor-dependent and/or -independent activation of guanine nucleotide-binding proteins by histamine and 2-substituted histamine derivatives in human leukemia (HL-60) and human erythroleukemia (HEL) cells Biochem. Pharmacol. 49 1995 901 914
    • (1995) Biochem. Pharmacol. , vol.49 , pp. 901-914
    • Hagelüken, A.1
  • 155
    • 0028952098 scopus 로고
    • Cationic-amphiphilic arpromidine-derived guanidines and a histamine trifluoromethyl-toluidied derivative may activate pertussis toxin-sensitive G-proteins by a receptor-independent mechanism
    • A. Hagelüken Cationic-amphiphilic arpromidine-derived guanidines and a histamine trifluoromethyl-toluidied derivative may activate pertussis toxin-sensitive G-proteins by a receptor-independent mechanism Naunyn Schmiedebergs Arch. Pharmacol. 351 1995 305 308
    • (1995) Naunyn Schmiedebergs Arch. Pharmacol. , vol.351 , pp. 305-308
    • Hagelüken, A.1
  • 156
    • 33746265828 scopus 로고    scopus 로고
    • 2-agonist activity in monocytes
    • 2-agonist activity in monocytes Mol. Pharmacol. 70 2006 450 453
    • (2006) Mol. Pharmacol. , vol.70 , pp. 450-453
    • Takahasi, H.K.1
  • 157
  • 158
    • 0030174309 scopus 로고    scopus 로고
    • Mapping epitope structure and activity: From one-dimensional prediction to four-dimensional description of antigenic specificity
    • M.H.V. Van Regenmortel Mapping epitope structure and activity: from one-dimensional prediction to four-dimensional description of antigenic specificity Methods 9 1996 465 472
    • (1996) Methods , vol.9 , pp. 465-472
    • Van Regenmortel, M.H.V.1
  • 159
    • 34248594570 scopus 로고    scopus 로고
    • Identification of discontinuous antigenic determinants on proteins based on shape complementarities
    • R. Rapberger Identification of discontinuous antigenic determinants on proteins based on shape complementarities J. Mol. Recognit. 20 2007 113 121
    • (2007) J. Mol. Recognit. , vol.20 , pp. 113-121
    • Rapberger, R.1
  • 160
    • 84858440181 scopus 로고    scopus 로고
    • Production and characterization of peptide antibodies
    • N.H. Trier Production and characterization of peptide antibodies Methods 56 2012 136 144
    • (2012) Methods , vol.56 , pp. 136-144
    • Trier, N.H.1
  • 161
    • 60849114733 scopus 로고    scopus 로고
    • Lack of specificity of antibodies directed against human β-adrenergic receptors
    • N. Hamdani, and J. van der Velden Lack of specificity of antibodies directed against human β-adrenergic receptors Naunyn Schmiedebergs Arch. Pharmacol. 379 2009 403 407
    • (2009) Naunyn Schmiedebergs Arch. Pharmacol. , vol.379 , pp. 403-407
    • Hamdani, N.1    Van Der Velden, J.2
  • 163
    • 60849115247 scopus 로고    scopus 로고
    • Should we be cautious on the use of commercially available antibodies to dopamine receptors?
    • S. Bodei Should we be cautious on the use of commercially available antibodies to dopamine receptors? Naunyn Schmiedebergs Arch. Pharmacol. 379 2009 413 415
    • (2009) Naunyn Schmiedebergs Arch. Pharmacol. , vol.379 , pp. 413-415
    • Bodei, S.1
  • 164
    • 34447633368 scopus 로고    scopus 로고
    • Conformational complexity of G-protein-coupled receptors
    • B.K. Kobilka, and X. Deupi Conformational complexity of G-protein-coupled receptors Trends Pharmacol. Sci. 28 2007 397 406
    • (2007) Trends Pharmacol. Sci. , vol.28 , pp. 397-406
    • Kobilka, B.K.1    Deupi, X.2
  • 165
    • 80053534393 scopus 로고    scopus 로고
    • Electroporation-aided DNA immunization generates polyclonal antibodies against the native conformation of human endothelin B receptor
    • B. Allard Electroporation-aided DNA immunization generates polyclonal antibodies against the native conformation of human endothelin B receptor DNA Cell Biol. 30 2011 727 737
    • (2011) DNA Cell Biol. , vol.30 , pp. 727-737
    • Allard, B.1
  • 166
    • 35348819390 scopus 로고    scopus 로고
    • Properties, production, and applications of camelid single-domain antibody fragments
    • M.M. Harmsen, and H.J. De Haard Properties, production, and applications of camelid single-domain antibody fragments Appl. Microbiol. Biotechnol. 77 2007 13 22
    • (2007) Appl. Microbiol. Biotechnol. , vol.77 , pp. 13-22
    • Harmsen, M.M.1    De Haard, H.J.2
  • 167
    • 0018246950 scopus 로고
    • 2 receptors
    • 2 receptors Nature 276 1978 403 405
    • (1978) Nature , vol.276 , pp. 403-405
    • Durant, G.J.1
  • 168
    • 60849131744 scopus 로고    scopus 로고
    • 4 receptor radioligand
    • 4 receptor radioligand ChemMedChem 4 2009 225 231
    • (2009) ChemMedChem , vol.4 , pp. 225-231
    • Igel, P.1
  • 169
    • 0026611862 scopus 로고
    • 2-receptor agonists. Synthesis, in vitro pharmacology, and qualitative structure-activity relationships of substituted 4- and 5-(2-aminoethyl)thiazoles
    • 2-receptor agonists. Synthesis, in vitro pharmacology, and qualitative structure-activity relationships of substituted 4- and 5-(2-aminoethyl)thiazoles J. Med. Chem. 35 1992 3239 3246
    • (1992) J. Med. Chem. , vol.35 , pp. 3239-3246
    • Eriks, J.C.1
  • 170
    • 60849086192 scopus 로고    scopus 로고
    • 2 receptor agonists
    • 2 receptor agonists ChemMedChem 4 2009 232 240
    • (2009) ChemMedChem , vol.4 , pp. 232-240
    • Kraus, A.1
  • 171
    • 84856837790 scopus 로고    scopus 로고
    • 2 receptor agonists
    • 2 receptor agonists J. Med. Chem. 55 2012 1147 1160
    • (2012) J. Med. Chem. , vol.55 , pp. 1147-1160
    • Birnkammer, T.1
  • 172
    • 0029661861 scopus 로고    scopus 로고
    • 3-receptor antagonists with benzyl ether structure or related moieties: Synthesis and structure-activity relationships
    • 3-receptor antagonists with benzyl ether structure or related moieties: synthesis and structure-activity relationships Arch. Pharm. (Weinheim) 329 1996 379 385
    • (1996) Arch. Pharm. (Weinheim) , vol.329 , pp. 379-385
    • Hüls, A.1
  • 173
    • 0141702358 scopus 로고    scopus 로고
    • 3 receptors in vitro and in vivo
    • 3 receptors in vitro and in vivo Proc. Natl. Acad. Sci. U.S.A. 100 2003 11086 11091
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , pp. 11086-11091
    • Gbahou, F.1
  • 174
    • 33750993771 scopus 로고    scopus 로고
    • 4 receptor agonist
    • 4 receptor agonist J. Med. Chem. 49 2006 6650 6651
    • (2006) J. Med. Chem. , vol.49 , pp. 6650-6651
    • Lim, H.D.1
  • 175
    • 33746725305 scopus 로고    scopus 로고
    • 4 receptor binding site. Part 1. Synthesis and pharmacological evaluation of dibenzodiazepine derivatives
    • 4 receptor binding site. Part 1. Synthesis and pharmacological evaluation of dibenzodiazepine derivatives J. Med. Chem. 49 2006 4512 4516
    • (2006) J. Med. Chem. , vol.49 , pp. 4512-4516
    • Smits, R.A.1
  • 176
    • 58149098872 scopus 로고    scopus 로고
    • 4 receptor inverse agonists using a scaffold hopping approach
    • 4 receptor inverse agonists using a scaffold hopping approach J. Med. Chem. 51 2008 7855 7865
    • (2008) J. Med. Chem. , vol.51 , pp. 7855-7865
    • Smits, R.A.1
  • 177
    • 56749178895 scopus 로고    scopus 로고
    • 4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia
    • 4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia J. Med. Chem. 51 2008 7094 7098
    • (2008) J. Med. Chem. , vol.51 , pp. 7094-7098
    • Liu, H.1
  • 179
    • 34248598463 scopus 로고    scopus 로고
    • 2 receptor determine the species selectivity of guanidine-type agonists and
    • 2 receptor determine the species selectivity of guanidine-type agonists and increase constitutive activity J. Pharmacol. Exp. Ther. 321 2007 975 982
    • (2007) J. Pharmacol. Exp. Ther. , vol.321 , pp. 975-982
    • Preuss, H.1
  • 184
    • 0032570329 scopus 로고    scopus 로고
    • sα has properties of a constitutively active receptor
    • sα has properties of a constitutively active receptor J. Biol. Chem. 273 1998 5109 5116
    • (1998) J. Biol. Chem. , vol.273 , pp. 5109-5116
    • Seifert, R.1
  • 185
    • 0028955687 scopus 로고
    • The Drosophila cation channel trpl expressed in insect Sf9 cells is stimulated by agonists of G-protein-coupled receptors
    • C. Harteneck The Drosophila cation channel trpl expressed in insect Sf9 cells is stimulated by agonists of G-protein-coupled receptors FEBS Lett. 358 1995 297 300
    • (1995) FEBS Lett. , vol.358 , pp. 297-300
    • Harteneck, C.1
  • 186
    • 0029658171 scopus 로고    scopus 로고
    • 2 histamine receptor to phospholipase C
    • 2 histamine receptor to phospholipase C Mol. Endocrinol. 10 1996 1697 1707
    • (1996) Mol. Endocrinol. , vol.10 , pp. 1697-1707
    • Kühn, B.1
  • 187
    • 0030872989 scopus 로고    scopus 로고
    • G proteins endogenously expressed in Sf 9 cells: Interactions with mammalian histamine receptors
    • D. Leopoldt G proteins endogenously expressed in Sf 9 cells: interactions with mammalian histamine receptors Naunyn Schmiedebergs Arch. Pharmacol. 356 1997 216 224
    • (1997) Naunyn Schmiedebergs Arch. Pharmacol. , vol.356 , pp. 216-224
    • Leopoldt, D.1
  • 189
    • 0028105946 scopus 로고
    • 1-histamine-receptor cDNA in Chinese hamster ovary cells. Pharmacological characterisation of the protein, tissue distribution of messenger RNA and chromosomal localisation of the gene
    • 1-histamine- receptor cDNA in Chinese hamster ovary cells. Pharmacological characterisation of the protein, tissue distribution of messenger RNA and chromosomal localisation of the gene Eur. J. Biochem. 224 1994 489 495
    • (1994) Eur. J. Biochem. , vol.224 , pp. 489-495
    • Moguilevsky, N.1
  • 190
    • 0025828485 scopus 로고
    • 3H]-tiotidine binding
    • 3H]-tiotidine binding Br. J. Pharmacol. 103 1991 1573 1579
    • (1991) Br. J. Pharmacol. , vol.103 , pp. 1573-1579
    • Hattori, Y.1
  • 192
    • 0025923441 scopus 로고
    • 2-receptors on human gastric carcinoma cell line MKN-45 and their increase by retinoic acid treatment
    • 2-receptors on human gastric carcinoma cell line MKN-45 and their increase by retinoic acid treatment Biochem. Biophys. Res. Commun. 176 1991 1027 1032
    • (1991) Biochem. Biophys. Res. Commun. , vol.176 , pp. 1027-1032
    • Arima, N.1
  • 193
    • 0033638021 scopus 로고    scopus 로고
    • 3 receptors: Role of two amino acids in the third transmembrane domain
    • 3 receptors: role of two amino acids in the third transmembrane domain Br. J. Pharmacol. 131 2000 1247 1250
    • (2000) Br. J. Pharmacol. , vol.131 , pp. 1247-1250
    • Ligneau, X.1
  • 194
    • 33645551062 scopus 로고    scopus 로고
    • 4 receptors: Structure-activity relationships of histamine derivatives
    • 4 receptors: structure-activity relationships of histamine derivatives Br. J. Pharmacol. 147 2006 744 754
    • (2006) Br. J. Pharmacol. , vol.147 , pp. 744-754
    • Gbahou, F.1
  • 196
    • 36448938182 scopus 로고    scopus 로고
    • 2 receptor do not affect the species-selective activity of guanidine-type agonists
    • 2 receptor do not affect the species-selective activity of guanidine-type agonists Naunyn Schmiedebergs Arch. Pharmacol. 376 2007 253 264
    • (2007) Naunyn Schmiedebergs Arch. Pharmacol. , vol.376 , pp. 253-264
    • Preuss, H.1
  • 198
    • 78049267227 scopus 로고    scopus 로고
    • Sf9 cells: A versatile model system to investigate the pharmacological properties of G protein-coupled receptors
    • E.H. Schneider, and R. Seifert Sf9 cells: a versatile model system to investigate the pharmacological properties of G protein-coupled receptors Pharmacol. Ther. 128 2010 387 418
    • (2010) Pharmacol. Ther. , vol.128 , pp. 387-418
    • Schneider, E.H.1    Seifert, R.2
  • 199
    • 78049525762 scopus 로고    scopus 로고
    • Fusion proteins as model systems for the analysis of constitutive GPCR activity
    • E.H. Schneider, and R. Seifert Fusion proteins as model systems for the analysis of constitutive GPCR activity Methods Enzymol. 485 2010 459 480
    • (2010) Methods Enzymol. , vol.485 , pp. 459-480
    • Schneider, E.H.1    Seifert, R.2
  • 200
    • 78649810475 scopus 로고    scopus 로고
    • Coexpression systems as models for the analysis of constitutive GPCR activity
    • E.H. Schneider, and R. Seifert Coexpression systems as models for the analysis of constitutive GPCR activity Methods Enzymol. 485 2010 527 557
    • (2010) Methods Enzymol. , vol.485 , pp. 527-557
    • Schneider, E.H.1    Seifert, R.2
  • 204
    • 0026755609 scopus 로고
    • Analysis and refinement of criteria for predicting the structure and relative orientations of transmembranal helical domains
    • J.A. Ballesteros, and H. Weinstein Analysis and refinement of criteria for predicting the structure and relative orientations of transmembranal helical domains Biophys. J. 62 1992 107 109
    • (1992) Biophys. J. , vol.62 , pp. 107-109
    • Ballesteros, J.A.1    Weinstein, H.2
  • 205
  • 208
    • 0028022026 scopus 로고
    • 1 receptor: Roles of aspartic acid107, asparagine198 and threonine194
    • 1 receptor: roles of aspartic acid107, asparagine198 and threonine194 Biochem. Biophys. Res. Commun. 203 1994 1096 1101
    • (1994) Biochem. Biophys. Res. Commun. , vol.203 , pp. 1096-1101
    • Ohta, K.1
  • 209
    • 0026644846 scopus 로고
    • 2 receptor
    • 2 receptor J. Biol. Chem. 267 1992 20840 20843
    • (1992) J. Biol. Chem. , vol.267 , pp. 20840-20843
    • Gantz, I.1
  • 213
    • 79960070651 scopus 로고    scopus 로고
    • 1 receptor complex with doxepin
    • 1 receptor complex with doxepin Nature 475 2011 65 70
    • (2011) Nature , vol.475 , pp. 65-70
    • Shimamura, T.1
  • 214
    • 36448995359 scopus 로고    scopus 로고
    • 2-adrenergic G protein-coupled receptor
    • 2-adrenergic G protein-coupled receptor Science 318 2007 1258 1265
    • (2007) Science , vol.318 , pp. 1258-1265
    • Cherezov, V.1
  • 215
    • 78651411166 scopus 로고    scopus 로고
    • 2 adrenoceptor
    • 2 adrenoceptor Nature 469 2011 175 180
    • (2011) Nature , vol.469 , pp. 175-180
    • Rasmussen, S.G.F.1
  • 216
    • 2942532422 scopus 로고    scopus 로고
    • Development and testing of a general amber force field
    • J. Wang Development and testing of a general amber force field J. Comput. Chem. 25 2004 1157 1174
    • (2004) J. Comput. Chem. , vol.25 , pp. 1157-1174
    • Wang, J.1
  • 217
    • 84988115618 scopus 로고
    • Validation of the general purpose tripos 5.2 force field
    • M. Clark Validation of the general purpose tripos 5.2 force field J. Comput. Chem. 10 1989 982 1012
    • (1989) J. Comput. Chem. , vol.10 , pp. 982-1012
    • Clark, M.1


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