Multidrug resistance protein 4 (MRP4/ABCC4) regulates cAMP cellular levels and controls human leukemia cell proliferation and differentiation

Journal of Biological Chemistry

Volumn 286, Issue 9, 2011, Pages 6979-6988

  Copsel, Sabrina ^a,b,c   Garcia, Corina ^a,c   Diez, Federico ^a   Vermeulem, Monica ^c,d   Baldi, Alberto ^b,c   Bianciotti, Liliana G ^a,c   Russel, Frans G M ^e   Shayo, Carina ^b,c   Davio, Carlos ^a,c  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b INST DE BIOL Y MED EXPERIMENTAL   (Argentina)

^c Consejo Nacional de Investigaciones Científicas Y Técnicas ^*  (Argentina)

^d INST DE INVEST HEMATOLOGICAS   (Argentina)

^e RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE MYELOID LEUKEMIA; CELLULAR LEVELS; HUMAN LEUKEMIA CELLS; INTRACELLULAR CAMP; LEUKEMIC CELLS; MULTIDRUG RESISTANCE; PDE4 INHIBITOR; PHOSPHODIESTERASES; PROBENECID; U937 CELL;

CELL CULTURE; CELL PROLIFERATION; DISEASES; EXTRUSION;

FETAL MONITORING;

ADENOSINE TRIPHOSPHATE; AMTHAMINE; CYCLIC AMP; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 4; PHOSPHODIESTERASE IV INHIBITOR; PROBENECID; SHORT HAIRPIN RNA;

ACUTE GRANULOCYTIC LEUKEMIA; ARTICLE; CELL CYCLE ARREST; CELL DIFFERENTIATION; CELL MATURATION; CELL PROLIFERATION; CELL STRAIN HL 60; CELL STRAIN U937; CONTROLLED STUDY; HUMAN; HUMAN CELL; LEUKEMIA CELL; LEUKEMIA CELL LINE; PRIORITY JOURNAL; PROTEIN TRANSPORT;

CELL DIFFERENTIATION; CELL DIVISION; CYCLIC AMP; DRUG DESIGN; HL-60 CELLS; HUMANS; LEUKEMIA, MYELOID, ACUTE; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; PHOSPHODIESTERASE 4 INHIBITORS; PROBENECID; RNA, SMALL INTERFERING; ROLIPRAM; SIGNAL TRANSDUCTION; THIAZOLES; U937 CELLS;

EID: 79953191123     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.166868     Document Type: Article

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