Modulation of histamine H3 receptor function by monovalent ions

Neuroscience Letters

Volumn 472, Issue 2, 2010, Pages 114-118

  Schnell, David ^a   Seifert, Roland ^b  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Asp2.50; Constitutive activity; D2.50N; Gi Go proteins; GTPase; Histamine H3 receptor; Monovalent ions; Na+; Sf9 insect cells

Indexed keywords

ASPARTIC ACID; BROMIDE ION; CHLORIDE ION; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; GUANOSINE TRIPHOSPHATASE; HISTAMINE H3 RECEPTOR; IODIDE ION; LITHIUM ION; N METHYLHISTAMINE; POTASSIUM ION; SODIUM CHLORIDE; SODIUM ION; THIOPERAMIDE;

AMINO ACID ANALYSIS; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; CELL MEMBRANE; CONTROLLED STUDY; ENZYME ASSAY; INSECT CELL; MOLECULAR MODEL; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; SIGNAL TRANSDUCTION; STEADY STATE;

ANIMALS; ANIONS; CATIONS, MONOVALENT; CELL LINE; GTP-BINDING PROTEINS; HALOGENS; HISTAMINE AGONISTS; HUMANS; INSECTS; METALS, ALKALI; MUTATION; RADIOLIGAND ASSAY; RECEPTORS, HISTAMINE H3; SIGNAL TRANSDUCTION;

EID: 77349123734     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2010.01.065     Document Type: Article

References (19)

1. 3 receptor. Trends Pharmacol. Sci. 28 (2007) 350-357
2. Haas H.L., Sergeeva O.A., and Selbach O. Histamine in the nervous system. Physiol. Rev. 88 (2008) 1183-1241
3. Higashijima T., Ferguson K.M., and Sternweis P.C. Regulation of hormone-sensitive GTP-dependent regulatory proteins by chloride. J. Biol. Chem. 262 (1987) 3597-3602
4. 2-adrenergic receptors by sodium. J. Biol. Chem. 265 (1990) 21590-21595
5. o-proteins in Sf9 insect cells. Naunyn. Schmiedebergs Arch. Pharmacol. 378 (2008) 261-274
6. Laugwitz K.L., Spicher K., Schultz G., and Offermanns S. Identification of receptor-activated G proteins: selective immunoprecipitation of photolabeled G-protein α subunits. Methods Enzymol. 237 (1994) 283-294
7. 3 receptor drugs. Nat. Rev. Drug Discov. 4 (2005) 107-120
8. 2-adrenergic receptor in membrane and solubilized preparations. Mol. Pharmacol. 21 (1982) 609-617
9. 2A-adrenergic receptor in vivo by gene targeting strategies reveals the role of this subtype in multiple physiological settings. Recent Prog. Horm. Res. 53 (1998) 25-42
10. 3 receptors regulates histamine neurons in brain. Nature 408 (2000) 860-864
11. 125I]epidepride, a high-affinity substituted benzamide ligand. J. Pharmacol. Exp. Ther. 252 (1990) 1108-1116
12. 4-receptor. Biochemistry 48 (2009) 1424-1438
13. o protein heterotrimers, J. Pharmacol. Exp. Ther., in press.
14. s alpha splice variants. J. Pharmacol. Exp. Ther. 298 (2001) 840-847
15. Seifert R., and Wenzel-Seifert K. Constitutive activity of G-protein-coupled receptors: cause of disease and common property of wild-type receptors. Naunyn. Schmiedebergs Arch. Pharmacol. 366 (2002) 381-416
16. + as universal stabilizer of the inactive (R) state. Receptors Channels 7 (2001) 357-369
17. Seifert R., and Wenzel-Seifert K. The human formyl peptide receptor as model system for constitutively active G-protein-coupled receptors. Life Sci. 73 (2003) 2263-2280
18. 2-adrenoceptor that blocks coupling to potassium but not calcium currents. Science 257 (1992) 977-980
19. i-family G protein subtypes. FEBS Lett. 462 (1999) 459-463