Sf9 cells: A versatile model system to investigate the pharmacological properties of G protein-coupled receptors

Pharmacology and Therapeutics

Volumn 128, Issue 3, 2010, Pages 387-418

  Schneider, Erich H ^a   Seifert, Roland ^b  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Constitutive activity; Functional reconstitution; G protein; GPCR; Protein expression; Sf9 insect cells

Indexed keywords

ADENYLATE CYCLASE; BETA ADRENERGIC RECEPTOR; CALCIUM; CYCLIC AMP; DOPAMINE 1 RECEPTOR; DOPAMINE RECEPTOR; ENDOTHELIN RECEPTOR; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR KINASE; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE TRIPHOSPHATASE; HISTAMINE H1 RECEPTOR; HISTAMINE H2 RECEPTOR; HISTAMINE RECEPTOR; HYBRID PROTEIN; INOSITOL PHOSPHATE; LUTEINIZING HORMONE RECEPTOR; LYSOPHOSPHATIDIC ACID RECEPTOR; MELANOCORTIN RECEPTOR; METABOTROPIC RECEPTOR; MUSCARINIC RECEPTOR; NEUROTENSIN RECEPTOR; NOLPITANTIUM; OXOTREMORINE; PHOSPHOLIPASE C; RADIOLIGAND; SEROTONIN 2 RECEPTOR; SEROTONIN RECEPTOR; TACHYKININ RECEPTOR; THROMBIN RECEPTOR;

ANTIBODY TITER; BACULOVIRUS EXPRESSION SYSTEM; BINDING AFFINITY; CELL CULTURE; CELL GROWTH; CELL MEMBRANE; CELL STRAIN SF9; CONFOCAL MICROSCOPY; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME PHOSPHORYLATION; HUMAN; HYDROLYSIS; INSECT CELL; LIGAND BINDING; MAMMAL CELL; NONHUMAN; PALMITOYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN INTERACTION; RADIOIMMUNOASSAY; RECEPTOR BINDING; REVIEW; SIGNAL TRANSDUCTION; STOICHIOMETRY; VIRUS INFECTION;

ANIMALS; BACULOVIRIDAE; CELL LINE; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; GTP-BINDING PROTEINS; MODELS, BIOLOGICAL; PROTEIN BINDING; RADIOLIGAND ASSAY; RECEPTORS, G-PROTEIN-COUPLED; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; SPODOPTERA;

EID: 78049267227     PISSN: 01637258     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2010.07.005     Document Type: Review

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