Incomplete activation of human eosinophils via the histamine H 4-receptor: Evidence for ligand-specific receptor conformations

Biochemical Pharmacology

Volumn 84, Issue 2, 2012, Pages 192-203

  Reher, Till M ^a   Neumann, Detlef ^a   Buschauer, Armin ^b   Seifert, Roland ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

Chemotaxis; Eosinophils; Functional selectivity; Histamine H 4 receptor; Intracellular calcium concentration

Indexed keywords

1 (5 CHLORO 2 INDOLYLCARBONYL) 4 METHYLPIPERAZINE; 2 CYANO 1 [4 (1H IMIDAZOL 4 YL)BUTYL] 3 (2 PHENYLTHIO)ETHYL GUANIDINE; CALCIUM ION; EOSINOPHIL PEROXIDASE; EOTAXIN; FAMOTIDINE; HISTAMINE; HISTAMINE AGONIST; HISTAMINE H2 RECEPTOR; HISTAMINE H4 RECEPTOR; LIGAND; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; UR P1376;

ARTICLE; CALCIUM CELL LEVEL; CELL ACTIVATION; CELL FUNCTION; CHEMOTAXIS; CONTROLLED STUDY; ENZYME RELEASE; EOSINOPHIL; EVIDENCE BASED PRACTICE; HUMAN; HUMAN CELL; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN PURIFICATION;

CALCIUM; CELLS, CULTURED; CHEMOKINE CCL11; CHEMOTAXIS; EOSINOPHIL PEROXIDASE; EOSINOPHILS; GUANIDINES; HUMANS; IMIDAZOLES; INDOLES; LIGANDS; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; PIPERAZINES; REACTIVE OXYGEN SPECIES; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, HISTAMINE;

EID: 84861229120     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2012.04.004     Document Type: Article

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