The histamine H4 receptor mediates allergic airway inflammation by regulating the activation of CD4+ T cells

Journal of Immunology

Volumn 176, Issue 11, 2006, Pages 7062-7070

  Dunford, Paul J ^a   O'Donnell, Niall ^a   Riley, Jason P ^a   Williams, Kacy N ^a   Karlsson, Lars ^a   Thurmond, Robin L ^a  

^a JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

(5 CHLORO 1H BENZOIMIDAZOL 2 YL)(4 METHYLPIPERAZIN 1 YL)METHANONE; (5 CHLORO 1H INDOL 2 YL)(4 METHYLPIPERAZIN 1 YL)METHANONE; ANTIHISTAMINIC AGENT; HISTAMINE H4 RECEPTOR; HISTAMINE H4 RECEPTOR ANTAGONIST; JNJ 10191584; JNJ 7777120; LORATADINE; UNCLASSIFIED DRUG; 1 ((5 CHLORO 1H INDOL 2 YL)CARBONYL) 4 METHYLPIPERAZINE; 1-((5-CHLORO-1H-INDOL-2-YL)CARBONYL)-4-METHYLPIPERAZINE; ALLERGEN; BENZIMIDAZOLE DERIVATIVE; CYTOKINE; G PROTEIN COUPLED RECEPTOR; HISTAMINE RECEPTOR; HRH4 PROTEIN, MOUSE; INDOLE DERIVATIVE; OVALBUMIN; PIPERAZINE DERIVATIVE;

AIRWAY; ALLERGIC DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASTHMA; CD4+ T LYMPHOCYTE; CELL FUNCTION; CELL INFILTRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; EOSINOPHIL; EX VIVO STUDY; IMMUNE RESPONSE; IMMUNE SYSTEM; INFLAMMATION; LYMPHOCYTIC INFILTRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR INTRINSIC ACTIVITY; T LYMPHOCYTE ACTIVATION; TH2 CELL; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; CELL CULTURE; CYTOLOGY; DISEASE MODEL; DRUG ANTAGONISM; FEMALE; GENETICS; IMMUNOLOGY; LUNG; LYMPHOCYTE ACTIVATION; METABOLISM; MOUSE MUTANT; PATHOLOGY; PHYSIOLOGY; RESPIRATORY TRACT ALLERGY; TRANSGENIC MOUSE;

ALLERGENS; ANIMALS; BENZIMIDAZOLES; CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; CYTOKINES; DISEASE MODELS, ANIMAL; FEMALE; INDOLES; INFLAMMATION; LUNG; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; MICE, MUTANT STRAINS; MICE, TRANSGENIC; OVALBUMIN; PIPERAZINES; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, HISTAMINE; RESPIRATORY HYPERSENSITIVITY;

EID: 33646857548     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.176.11.7062     Document Type: Article

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