Histamine induces cytoskeletal changes in human eosinophils via the H 4 receptor

British Journal of Pharmacology

Volumn 140, Issue 6, 2003, Pages 1117-1127

  Buckland, Karen F ^a   Williams, Timothy J ^a   Conroy, Dolores M ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Actin polymerisation; Eosinophils; Histamine; Shape change

Indexed keywords

ACTIN; ALPHA METHYLHISTAMINE; CALCIUM ION; CD11B ANTIGEN; CELL ADHESION MOLECULE; CIMETIDINE; CLOBENPROPIT; CLOZAPINE; EOTAXIN; HISTAMINE; HISTAMINE DERIVATIVE; HISTAMINE H1 RECEPTOR ANTAGONIST; HISTAMINE H2 RECEPTOR ANTAGONIST; HISTAMINE H3 RECEPTOR ANTAGONIST; HISTAMINE H4 RECEPTOR; IMETIT; MEPYRAMINE; N METHYLHISTAMINE; PERTUSSIS TOXIN; THIOPERAMIDE;

ARTICLE; AUTOFLUORESCENCE; BASOPHIL; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL STRUCTURE; CHEMOTAXIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSKELETON; EOSINOPHIL; HUMAN; HUMAN CELL; MORPHOLOGICAL TRAIT; NEUTROPHIL; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN POLYMERIZATION; STATISTICAL SIGNIFICANCE; UPREGULATION;

ACTINS; ANTIGENS, CD11B; CALCIUM; CELL SIZE; CHEMOKINES, CC; CHEMOTAXIS; CLOZAPINE; CYTOSKELETON; DOSE-RESPONSE RELATIONSHIP, DRUG; EOSINOPHILS; HISTAMINE; HISTAMINE AGONISTS; HISTAMINE ANTAGONISTS; HUMANS; IMIDAZOLES; PERTUSSIS TOXIN; PIPERIDINES; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, HISTAMINE; THIOUREA; UP-REGULATION;

EID: 0344826048     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0705530     Document Type: Article

References (53)

1. ARRANG, J.M., GARBARG, M., LANCELOT, J.C., LECOMTE, J.M., POLLARD, H., ROBBA, M., SCHUNACK, W. & SCHWARTZ, J.C. (1987). Highly potent and selective ligands for histamine H3-receptors. Nature, 327, 117-123.
2. ARRANG, J.M., GARBARG, M. & SCHWARTZ, J.C. (1983). Autoinhibition of brain histamine release mediated by a novel class (H3) of histamine receptor. Nature, 302, 832-837.
3. ASH, A.S. & SCHILD, H.O. (1966). Receptors mediating some actions of histamine. Br. J. Pharmacol., 27, 427-439.
4. BISSONNETTE, E.Y. (1996). Histamine inhibits tumor necrosis factor alpha release by mast cells through H2 and H3 receptors. Am. J. Respir. Cell Mol. Biol., 14, 620-626.
5. BOUSQUET, J., CHANEZ, P., LACOSTE, J.Y., BARNEON, G., GHAVANIAN, N., ENANDER, I., VENGE, P., AHLSTEDT, S., SIMONY-LAFONTAINE, J. & GODARD, P. (1990). Eosinophilic inflammation in asthma. N. Engl. J. Med., 323, 1033-1039.
6. BROIDE, D.H., GLEICH, G.J., CUOMO, A.J., COBURN, D.A., FEDERMAN, E.C., SCHWARTZ, L.B. & WASSERMAN, S.I. (1991). Evidence of ongoing mast cell and eosinophil degranulation in symptomatic asthma airway. J. Allergy Clin. Immunol., 88, 637-648.
7. BRYAN, S.A., JOSE, P.J., TOPPING, J.R., WILHELM, R., SODERBERG, C., KERTESZ, D., BARNES, P.J., WILLIAMS, T.J., HANSEL, T.T. & SABROE, I. (2002). Responses of leukocytes to chemokines in whole blood and their antagonism by novel CC-chemokine receptor 3 antagonists. Am. J. Respir. Crit. Care Med., 165, 1602-1609.
8. CAPRON, M., ROUSSEAUX, J., MAZINGUE, C., BAZIN, H. & CAPRON, A. (1978). Rat mast cell-eosinophil interaction in antibody-dependent eosinophil cytotoxicity to Schistosoma mansoni schistosomula. J. Immunol., 121, 2518-2525.
9. CARLSSON, R., DOHLSTEN, M. & SJOGREN, H.O. (1985). Histamine modulates the production of interferon-gamma and interleukin-2 by mitogen-activated human mononuclear blood cells. Cell. Immunol., 96, 104-112.
10. CARON, G., DELNESTE, Y., ROELANDTS, E., DUEZ, C., BONNEFOY, J.Y., PESTEL, J. & JEANNIN, P. (2001). Histamine polarizes human dendritic cells into Th2 cell-promoting effector dendritic cells. J. Immunol., 167, 3682-3686.
11. CLARK, R.A., GALLIN, J.I. & KAPLAN, A.P. (1975). The selective eosinophil chemotactic activity of histamine. J. Exp. Med., 142, 1462-1476.
12. CLARK, R.A.F., SANDLER, J.A., GALLIN, J.I. & KAPLAN, A.P. (1977). Histamine modulation of eosinophil migration. J. Immunol., 118, 137-145.
13. COGE, F., GUENIN, S.P., RIQUE, H., BOUTIN, J.A. & GALIZZI, J.P. (2001). Structure and expression of the human histamine H4-receptor gene. Biochem. Biophys. Res. Commun., 284, 301-309.
14. COLLINS, P.D., MARLEAU, S., GRIFFITHS-JOHNSON, D.A., JOSE, P.J. & WILLIAMS, T.J. (1995). Cooperation between interleukin-5 and the chemokine eotaxin to induce eosinophil accumulation in vivo. J. Exp. Med., 182, 1169-1174.
15. DOHLSTEN, M., KALLAND, T., SJOGREN, H.O. & CARLSSON, R. (1988). Histamine inhibits interleukin 1 production by lipopolysaccharide-stimulated human peripheral blood monocytes. Scand. J. Immunol., 27, 527-532.
16. EZEAMUZIE, C.I. & PHILIPS, E. (2000). Histamine H(2) receptors mediate the inhibitory effect of histamine on human eosinophil degranulation. Br. J. Pharmacol., 131, 482-488.
17. GANTNER, F., SAKAI, K., TUSCHE, M.W., CRUIKSHANK, W.W., CENTER, D.M. & BACON, K.B. (2002). Histamine h(4) and h(2) receptors control histamine-induced interleukin-16 release from human CD8(+) T cells. J. Pharmacol. Exp. Ther., 303, 300-307.
18. GIEMBYCZ, M.A. & LINDSAY, M.A. (1999). Pharmacology of the eosinophil. Pharmacol. Rev., 51, 213-340.
19. GLEICH, G.J., ADOLPHSON, C.R. & LEIFERMAN, K.M. (1993). The biology of the eosinophilic leukocyte. Annu. Rev. Med., 44, 85-101.
20. GROVE, D.I., MAHMOUD, A.A. & WARREN, K.S. (1977). Eosinophils and resistance to Trichinella spiralis. J. Exp. Med., 145, 755-759.
21. HANSEL, T.T., DE VRIES, I.J., IFF, T., RIHS, S., WANDZILAK., M., BETZ, S., BLASER, K. & WALKER, C. (1991). An improved immunomagnetic procedure for the isolation of highly purified human blood eosinophils. J. Immunol. Methods, 145, 105-110.
22. HART, P.H. (2001). Regulation of the inflammatory response in asthma by mast cell products. Immunol. Cell Biol., 79, 149-153.
23. HASLETT, C., GUTHRIE, L.A., KOPANIAK, M.M., JOHNSTON JR, R.B. & HENSON, P.M. (1985). Modulation of multiple neutrophil functions by preparative methods or trace concentrations of bacterial lipopolysaccharide. Am. J. Pathol., 119, 101-110.
24. HEINEMANN, A., HARTNELL, A., STUBBS, V.E., MURAKAMI, K., SOLER, D., LAROSA, G., ASKENASE, P.W., WILLIAMS, T.J. & SABROE, I. (2000). Basophil responses to chemokines are regulated by both sequential and cooperative receptor signaling. J. Immunol., 165, 7224-7233.
25. HILL, H.R. & QUIE, P.G. (1974). Raised serum-IgE levels and defective neutrophil chemotaxis in three children with eczema and recurrent bacterial infections. Lancet, 1, 183-187.
26. HILL, S.J. (1990). Distribution, properties, and functional characteristics of three classes of histamine receptor. Pharmacol. Rev., 42, 45-83.
27. HOFSTRA, C.L., DESAI, P.J., THURMOND, R.L. & FUNG-LEUNG, W.P. (2003). Histamine H4 receptor mediates chemotaxis and calcium mobilization of mast cells. J. Pharmacol. Exp. Ther., 305, 1212-1221.
28. KINET, J.P. (1999). The high-affinity IgE receptor (Fc epsilon RI): from physiology to pathology. Annu. Rev. Immunol., 17, 931-972.
29. LACOSTE, J.Y., BOUSQUET, J., CHANEZ, P., VAN VYVE, T., SIMONY-LAFONTAINE, J., LEQUEU, N., VIC, P., ENANDER, I., GODARD, P. & MICHEL, F.B. (1993). Eosinophilic and neutrophilic inflammation in asthma, chronic bronchitis, and chronic obstructive pulmonary disease. J. Allergy Clin. Immunol., 92, 537-548.
30. LIU, C., MA, X., JIANG, X., WILSON, S.J., HOFSTRA, C.L., BLEVITT, J., PYATI, J., LI X., CHAI, W., CARRUTHERS, N. & LOVENBERG, T.W. (2001a). Cloning and pharmacological characterization of a fourth histamine receptor (H(4)) expressed in bone marrow. Mol. Pharmacol., 59, 420-426.
31. LIU, C., WILSON, S.J., KUEI, C. & LOVENBERG, T.W. (2001b). Comparison of human, mouse, rat, and guinea pig histamine H4 receptors reveals substantial pharmacological species variation. J. Pharmacol. Exp. Ther., 299, 121-130.
32. LOVENBERG, T.W., ROLAND, B.L., WILSON, S.J., JIANG, X., PYATI, J., HUVAR, A., JACKSON, M.R. & ERLANDER, M.G. (1999). Cloning and functional expression of the human histamine H3 receptor. Mol. Pharmacol., 55, 1101-1107.
33. MCEWEN, B.J. (1992). Eosinophils: a review. Vet. Res. Commun., 16, 11-44.
34. MORSE, K.L., BEHAN, J., LAZ, T.M., WEST JR, R.E., GREENFEDER, S.A., ANTHES, J.C., UMLAND, S., WAN, Y., HIPKIN, R.W., GONSIOREK, W., SHIN, N., GUSTAFSON, E.L., QIAO, X., WANG, S., HEDRICK, J.A., GREENE, J., BAYNE, M. & MONSMA JR, F.J. (2001). Cloning and characterization of a novel human histamine receptor. J. Pharmacol. Exp. Ther., 296, 1058-1066.
35. NAKAMURA, T., ITADANI, H., HIDAKA, Y., OHTA, M. & TANAKA, K. (2000). Molecular cloning and characterization of a new human histamine receptor, HH4R. Biochem. Biophys. Res. Commun., 279, 615-620.
36. NGUYEN, T., SHAPIRO, D.A., GEORGE, S.R., SETOLA, V., LEE, D.K., CHENG, R., RAUSER, L., LEE, S.P., LYNCH, K.R., ROTH, B.L. & O'DOWD, B.F. (2001). Discovery of a novel member of the histamine receptor family. Mol. Pharmacol., 59, 427-433.
37. ODA, T., MATSUMOTO, S., MASUHO, Y., TAKASAKI, J., MATSUMOTO, M., KAMOHARA, M., SAITO, T., OHISHI, T., SOGA, T., HIYAMA, H., MATSUSHIME, H. & FURUICHI, K. (2002). cDNA cloning and characterization of porcine histamine H4 receptor. Biochim. Biophys. Acta, 1575, 135-138.
38. ODA, T., MORIKAWA, N., SAITO, Y., MASUHO, Y. & MATSUMOTO, S. (2000). Molecular cloning and characterization of a novel type of histamine receptor preferentially expressed in leukocytes. J. Biol. Chem., 275, 36781-36786.
39. O'REILLY, M., ALPERT, R., JENKINSON, S., GLADUE, R.P., FOO, S., TRIM, S., PETER, B., TREVETHICK, M. & FIDOCK, M. (2002). Identification of a histamine H4 receptor on human eosinophils -role in eosinophil chemotaxis. J. Receptor Signal Transduct. Res., 22, 431-448.
40. PINCUS, S.H., DINAPOLI, A.M. & SCHOOLEY, W.R. (1982). Superoxide production by eosinophils: activation by histamine. J. Invest. Dermatol., 79, 53-57.
41. RAIBLE, D.G., LENAHAN, T., FAYVILEVICH, Y., KOSINSKI, R. & SCHULMAN, E.S. (1994). Pharmacologic characterization of a novel histamine receptor on human eosinophils. Am. J. Respir. Crit. Care Med., 149, 1506-1511.
42. RAIBLE, D.G., SCHULMAN, E.S., DIMUZIO, J., CARDILLO, R. & POST, T.J. (1992). Mast cell mediators prostaglandin-D2 and histamine activate human eosinophils. J. Immunol., 148, 3536-3542.
43. SABROE, I., HARTNELL, A., JOPLING, L.A., BEL, S., PONATH, P.D., PEASE, J.E., COLLINS, P.D. & WILLIAMS, T.J. (1999). Differential regulation of eosinophil chemokine signaling via CCR3 and non-CCR3 pathways. J. Immunol., 162, 2946-2955.
44. SEHMI, R., WARDLAW, A.J., CROMWELL, O., KURIHARA, K., WALTMANN, P. & KAY, A.B. (1992). Interleukin-5 selectively enhances the chemotactic response of eosinophils obtained from normal but not eosinophilic subjects. Blood, 79, 2952-2959.
45. SHIN, N., COATES, E., MURGOLO, N.J., MORSE, K.L., BAYNE, M., STRADER, C.D. & MONSMA JR, F.J. (2002). Molecular modeling and site-specific mutagenesis of the histamine-binding site of the histamine H4 receptor. Mol. Pharmacol., 62, 38-47.
46. SIROIS, J., MENARD, G., MOSES, A.S. & BISSONNETTE, E.Y. (2000). Importance of histamine in the cytokine network in the lung through H2 and H3 receptors: stimulation of IL-10 production. J. Immunol., 164, 2964-2970.
47. STUBBS, V.E., SCHRATL, P., HARTNELL, A., WILLIAMS, T.J., PESKAR, B.A., HEINEMANN, A. & SABROE, I. (2002). Indomethacin causes PGD2-like and eotaxin-like selective responses in eosinophils and basophils. J. Biol. Chem., 277, 26012-26020.
48. TAKAFUJI, S., BISCHOFF, S.C., DE WECK, A.L. & DAHINDEN, C.A. (1991). IL-3 and IL-5 prime normal human eosinophils to produce leukotriene C4 in response to soluble agonists. J. Immunol., 147, 3855-3861.
49. WADEE, A.A., ANDERSON, R. & SHER, R. (1980). In vitro effects of histamine on eosinophil migration. Int. Arch. Allergy Appl. Immunol., 63, 322-329.
50. WELLER, P.F. (1991). The immunobiology of eosinophils. N. Engl. J. Med., 324, 1110-1118.
51. WHITE, M.V. (1990). The role of histamine in allergic diseases. J. Allergy Clin. Immunol., 86, 599-605.
52. ZHANG, L., SOARES, M.P., GUAN, Y., MATHERAVIDATHU, S., WNEK, R., JOHNSON, K.E., MEISHER, A., ILIFF, S.A., MUDGETT, J.S., SPRINGER, M.S. & DAUGHERTY, B.L. (2002). Functional expression and characterization of macaque C-C chemokine receptor 3 (CCR3) and generation of potent antagonistic anti-macaque CCR3 monoclonal antibodies. J. Biol. Chem., 277, 33799-33810.
53. ZHU, Y., MICHALOVICH, D., WU, H., TAN, K.B., DYTKO, G.M., MANNAN, I.J., BOYCE, R., ALSTON, J., TIERNEY, L.A., LI, X., HERRITY, N.C., VAWTER, L., SARAU, H.M., AMES, R.S., DAVENPORT, C.M., HIEBLE, J.P., WILSON, S., BERGSMA, D.J. & FITZGERALD, L.R. (2001). Cloning, expression, and pharmacological characterization of a novel human histamine receptor. Mol. Pharmacol., 59, 434-441.