Human memory Th17 cells express a functional histamine H4 receptor

American Journal of Pathology

Volumn 180, Issue 1, 2012, Pages 177-185

  Mommert, Susanne ^a   Gschwandtner, Maria ^a   Koether, Brigitta ^a   Gutzmer, Ralf ^a   Werfel, Thomas ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

HISTAMINE H4 RECEPTOR; INTERLEUKIN 17; INTERLEUKIN 23; IQ MOTIF CONTAINING GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN 1; MESSENGER RNA;

ARTICLE; CYTOKINE RELEASE; GEL MOBILITY SHIFT ASSAY; HUMAN; HUMAN CELL; IMMUNOMODULATION; INFLAMMATION; MEMORY T LYMPHOCYTE; POLARIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PSORIASIS; REAL TIME POLYMERASE CHAIN REACTION;

CELL DIFFERENTIATION; DERMATITIS, ATOPIC; DRUG COMBINATIONS; HUMANS; INTERLEUKIN-17; INTERLEUKIN-1BETA; INTERLEUKIN-23; METHYLHISTAMINES; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, HISTAMINE; TH17 CELLS; TRANSCRIPTION FACTOR AP-1;

EID: 83455258015     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2011.09.028     Document Type: Article

References (37)

1. T. Nakamura, H. Itadani, Y. Hidaka, M. Ohta, K. Tanaka Molecular cloning and characterization of a new human histamine receptor, HH4R Biochem Biophys Res Commun 279 2000 615 620 (Pubitemid 32016763)
2. T. Oda, N. Morikawa, Y. Saito, Y. Masuho, S. Matsumoto Molecular cloning and characterization of a novel type of histamine receptor preferentially expressed in leukocytes J Biol Chem 275 2000 36781 36786 (Pubitemid 32002087)
3. C.L. Hofstra, P.J. Desai, R.L. Thurmond, W.P. Fung-Leung Histamine H4 receptor mediates chemotaxis and calcium mobilization of mast cells J Pharmacol Exp Ther 305 2003 1212 1221 (Pubitemid 36618001)
4. P. Ling, K. Ngo, S. Nguyen, R.L. Thurmond, J.P. Edwards, L. Karlsson, W.P. Fung-Leung Histamine H4 receptor mediates eosinophil chemotaxis with cell shape change and adhesion molecule upregulation Br J Pharmacol 142 2004 161 171 (Pubitemid 38698205)
5. R. Gutzmer, C. Diestel, S. Mommert, B. Kother, H. Stark, M. Wittmann, T. Werfel Histamine H4 receptor stimulation suppresses IL-12p70 production and mediates chemotaxis in human monocyte-derived dendritic cells J Immunol 174 2005 5224 5232 (Pubitemid 40593160)
6. B.B. Damaj, C.B. Becerra, H.J. Esber, Y. Wen, A.A. Maghazachi Functional expression of H4 histamine receptor in human natural killer cells, monocytes, and dendritic cells J Immunol 179 2007 7907 7915
7. M. Gschwandtner, K. Schakel, T. Werfel, R. Gutzmer Histamine H(4) receptor activation on human slan-dendritic cells down-regulates their pro-inflammatory capacity Immunology 132 2011 49 56
8. D. Dijkstra, R. Leurs, P. Chazot, F.C. Shenton, H. Stark, T. Werfel, R. Gutzmer Histamine downregulates monocyte CCL2 production through the histamine H4 receptor J Allergy Clin Immunol 120 2007 300 307 (Pubitemid 47102370)
9. M. Gschwandtner, K. Rossbach, D. Dijkstra, W. Baumer, M. Kietzmann, H. Stark, T. Werfel, R. Gutzmer Murine and human Langerhans cells express a functional histamine H4 receptor: modulation of cell migration and function Allergy 65 2010 840 849
10. R. Gutzmer, S. Mommert, M. Gschwandtner, K. Zwingmann, H. Stark, T. Werfel The histamine H4 receptor is functionally expressed on T(H)2 cells J Allergy Clin Immunol 123 2009 619 625
11. M.A. Lowes, T. Kikuchi, J. Fuentes-Duculan, I. Cardinale, L.C. Zaba, A.S. Haider, E.P. Bowman, J.G. Krueger Psoriasis vulgaris lesions contain discrete populations of Th1 and Th17 T cells J Invest Dermatol 128 2008 1207 1211 (Pubitemid 351543220)
12. N.J. Wilson, K. Boniface, J.R. Chan, B.S. McKenzie, W.M. Blumenschein, J.D. Mattson, B. Basham, K. Smith, T. Chen, F. Morel, J.C. Lecron, R.A. Kastelein, D.J. Cua, T.K. McClanahan, E.P. Bowman, R. de Waal Malefyt Development, cytokine profile and function of human interleukin 17-producing helper T cells Nat Immunol 8 2007 950 957 (Pubitemid 47300009)
13. S. Kagami, H.L. Rizzo, J.J. Lee, Y. Koguchi, A. Blauvelt Circulating Th17 Th22, and Th1 cells are increased in psoriasis J Invest Dermatol 130 2010 1373 1383
14. M. Toda, D.Y. Leung, S. Molet, M. Boguniewicz, R. Taha, P. Christodoulopoulos, T. Fukuda, J.A. Elias, Q.A. Hamid Polarized in vivo expression of IL-11 and IL-17 between acute and chronic skin lesions J Allergy Clin Immunol 111 2003 875 881 (Pubitemid 36470263)
15. C. Koga, K. Kabashima, N. Shiraishi, M. Kobayashi, Y. Tokura Possible pathogenic role of Th17 cells for atopic dermatitis J Invest Dermatol 128 2008 2625 2630
16. K. Eyerich, D. Pennino, C. Scarponi, S. Foerster, F. Nasorri, H. Behrendt, J. Ring, C. Traidl-Hoffmann, C. Albanesi, A. Cavani IL-17 in atopic eczema: linking allergen-specific adaptive and microbial-triggered innate immune response J Allergy Clin Immunol 123 2009 59 66 e4
17. E. Guttman-Yassky, M.A. Lowes, J. Fuentes-Duculan, L.C. Zaba, I. Cardinale, K.E. Nograles, A. Khatcherian, I. Novitskaya, J.A. Carucci, R. Bergman, J.G. Krueger Low expression of the IL-23/Th17 pathway in atopic dermatitis compared to psoriasis J Immunol 181 2008 7420 7427
18. S.C. Liang, X.Y. Tan, D.P. Luxenberg, R. Karim, K. Dunussi-Joannopoulos, M. Collins, L.A. Fouser Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides J Exp Med 203 2006 2271 2279 (Pubitemid 44498362)
19. K.E. Nograles, M. Suarez-Farinas, A. Shemer, J. Fuentes-Duculan, A. Chiricozzi, I. Cardinale, L.C. Zaba, T. Kikuchi, M. Ramon, R. Bergman, J.G. Krueger, E. Guttman-Yassky Atopic dermatitis keratinocytes exhibit normal T(H)17 cytokine responses J Allergy Clin Immunol 125 2010 744 746 746.e1746.e2
20. + effector memory T cells J Immunol 180 2008 7948 7957
21. L. Yang, D.E. Anderson, C. Baecher-Allan, W.D. Hastings, E. Bettelli, M. Oukka, V.K. Kuchroo, D.A. Hafler IL-21 and TGF-beta are required for differentiation of human T(H)17 cells Nature 454 2008 350 352
22. + T cells and inhibits allergic asthma in a murine model J Immunol 178 2007 8081 8089 (Pubitemid 46898080)
23. W. Ouyang, J.K. Kolls, Y. Zheng The biological functions of T helper 17 cell effector cytokines in inflammation Immunity 28 2008 454 467 (Pubitemid 351471762)
24. T. Werfel The role of leukocytes, keratinocytes, and allergen-specific IgE in the development of atopic dermatitis J Invest Dermatol 129 2009 1878 1891
25. A.L. Krogstad, P. Lonnroth, G. Larson, B.G. Wallin Increased interstitial histamine concentration in the psoriatic plaque J Invest Dermatol 109 1997 632 635 (Pubitemid 27465916)
26. S. Stander, M. Steinhoff Pathophysiology of pruritus in atopic dermatitis: an overview Exp Dermatol 11 2002 12 24 (Pubitemid 36934620)
27. P.F. Cheung, C.K. Wong, C.W. Lam Molecular mechanisms of cytokine and chemokine release from eosinophils activated by IL-17A. IL-17F, and IL-23: implication for Th17 lymphocytes-mediated allergic inflammation J Immunol 180 2008 5625 5635
28. A. Doreau, A. Belot, J. Bastid, B. Riche, M.C. Trescol-Biemont, B. Ranchin, N. Fabien, P. Cochat, C. Pouteil-Noble, P. Trolliet, I. Durieu, J. Tebib, B. Kassai, S. Ansieau, A. Puisieux, J.F. Eliaou, N. Bonnefoy-Berard Interleukin 17 acts in synergy with B cell-activating factor to influence B cell biology and the pathophysiology of systemic lupus erythematosus Nat Immunol 10 2009 778 785
29. J.M. Cowden, M. Zhang, P.J. Dunford, R.L. Thurmond The histamine H(4) receptor mediates inflammation and pruritus in Th2-dependent dermal inflammation J Invest Dermatol 130 2010 1023 1033
30. Y. Zheng, D.M. Danilenko, P. Valdez, I. Kasman, J. Eastham-Anderson, J. Wu, W. Ouyang Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis Nature 445 2007 648 651 (Pubitemid 46232884)
31. Z. Chen, C.M. Tato, L. Muul, A. Laurence, J.J. O'Shea Distinct regulation of interleukin-17 in human T helper lymphocytes Arthritis Rheum 56 2007 2936 2946 (Pubitemid 47502740)
32. + T helper cells Cell 126 2006 1121 1133 (Pubitemid 44380299)
33. + T cells Eur J Immunol 39 2009 1480 1493
34. Z. Chen, A. Laurence, J.J. O'Shea Signal transduction pathways and transcriptional regulation in the control of Th17 differentiation Semin Immunol 19 2007 400 408
35. I.I. Ivanov, L. Zhou, D.R. Littman Transcriptional regulation of Th17 cell differentiation Semin Immunol 19 2007 409 417 (Pubitemid 351274050)
36. K.L. Morse, J. Behan, T.M. Laz, R.E. West Jr, S.A. Greenfeder, J.C. Anthes, S. Umland, Y. Wan, R.W. Hipkin, W. Gonsiorek, N. Shin, E.L. Gustafson, X. Qiao, S. Wang, J.A. Hedrick, J. Greene, M. Bayne, F.J. Monsma Jr Cloning and characterization of a novel human histamine receptor J Pharmacol Exp Ther 296 2001 1058 1066 (Pubitemid 32187382)
37. N. Matesanz, N. Lafuente, V. Azcutia, D. Martin, A. Cuadrado, J. Nevado, L. Rodriguez-Manas, C.F. Sanchez-Ferrer, C. Peiro Xanthine oxidase-derived extracellular superoxide anions stimulate activator protein 1 activity and hypertrophy in human vascular smooth muscle via c-Jun N-terminal kinase and p38 mitogen-activated protein kinases J Hypertens 25 2007 609 618 (Pubitemid 46213800)