Species-dependent activities of G-protein-coupled receptor ligands: Lessons from histamine receptor orthologs

Trends in Pharmacological Sciences

Volumn 34, Issue 1, 2013, Pages 13-32

  Strasser, Andrea ^a   Wittmann, Hans Joachim ^a   Buschauer, Armin ^a   Schneider, Erich H ^b   Seifert, Roland ^b  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMTHAMINE; ARPROMIDINE; BIOGENIC AMINE; CHLORPHENIRAMINE; CIMETIDINE; CLOZAPINE; DIMAPRIT; DOXEPIN; FEXOFENADINE; G PROTEIN COUPLED RECEPTOR; HISTAMINE; HISTAMINE H1 RECEPTOR; HISTAMINE H2 RECEPTOR; HISTAMINE H3 RECEPTOR; HISTAMINE H4 RECEPTOR; HISTAMINE RECEPTOR; HISTAMINERGIC RECEPTOR AFFECTING AGENT; HISTAPRODIFEN; IMPROMIDINE; LIGAND; MEPYRAMINE; MIANSERIN; NEUROTRANSMITTER; PHENOPRODIFEN; PHENOPRODIFEN DERIVATIVE; PHENYLHISTAMINE; PROMETHAZINE; RECEPTOR SUBTYPE; SUPRAHISTAPRODIFEN; UNCLASSIFIED DRUG; UNINDEXED DRUG;

BINDING SITE; BIOLOGICAL ACTIVITY; DRUG DEVELOPMENT; DRUG STRUCTURE; HUMAN; LIGAND BINDING; NONHUMAN; ORTHOLOGY; PRIORITY JOURNAL; PROTEIN CONFORMATION; REVIEW; SPECIES DIFFERENCE; THERMODYNAMICS;

ANIMALS; HISTAMINE; HISTAMINE AGONISTS; HISTAMINE ANTAGONISTS; HUMANS; LIGANDS; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, HISTAMINE; SPECIES SPECIFICITY;

EID: 84871788150     PISSN: 01656147     EISSN: 18733735     Source Type: Journal    
DOI: 10.1016/j.tips.2012.10.004     Document Type: Review

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