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Volumn 71, Issue 1, 2011, Pages 109-122

Histamine dihydrochloride in the management of acute myeloid leukaemia

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMALARIAL AGENT; ANTITRYPANOSOMAL AGENT; HISTAMINE; INTERLEUKIN 2; MONOAMINE OXIDASE INHIBITOR;

EID: 78650959436     PISSN: 00126667     EISSN: 11791950     Source Type: Journal    
DOI: 10.2165/11206410-000000000-00000     Document Type: Article
Times cited : (30)

References (59)
  • 3
    • 70349256226 scopus 로고    scopus 로고
    • The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: Rationale and important changes
    • Jul 30
    • Vardiman JW, Thiele J, Arber DA, et al. The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes. Blood 2009 Jul 30; 114 (5): 937-51.
    • (2009) Blood , vol.114 , Issue.5 , pp. 937-51
    • Vardiman, J.W.1    Thiele, J.2    Arber, D.A.3
  • 4
    • 32144456451 scopus 로고    scopus 로고
    • Adult acute myeloid leukemia
    • [published erratum appears in Mayo Clin Proc 2006 Apr 81 (4) 569] Feb
    • Jabbour EJ, Estey E, Kantarjian HM. Adult acute myeloid leukemia [published erratum appears in Mayo Clin Proc 2006 Apr; 81 (4): 569]. Mayo Clin Proc 2006 Feb; 81 (2): 247-60.
    • (2006) Mayo Clin Proc , vol.81 , Issue.2 , pp. 247-60
    • Jabbour, E.J.1    Estey, E.2    Kantarjian, H.M.3
  • 5
    • 48749123878 scopus 로고    scopus 로고
    • Prognostic implications of gene mu-tations in acute myeloid leukemia with normal cytogenetics
    • Aug
    • Gaidzik V, Dohner K. Prognostic implications of gene mu-tations in acute myeloid leukemia with normal cytogenetics. Semin Oncol 2008 Aug; 35 (4): 346-55.
    • (2008) Semin Oncol , vol.35 , Issue.4 , pp. 346-55
    • Gaidzik, V.1    Dohner, K.2
  • 6
    • 33847375991 scopus 로고    scopus 로고
    • Epidemiology of hematological malignancies
    • Jan
    • Rodriguez-Abreu D, Bordoni A, Zucca E. Epidemiology of hematological malignancies. Ann Oncol 2007 Jan; 18 Suppl. 1:i3-8.
    • (2007) Ann Oncol , vol.18 , Issue.SUPPL. 1
    • Rodriguez-Abreu, D.1    Bordoni, A.2    Zucca, E.3
  • 7
    • 37549072095 scopus 로고    scopus 로고
    • National Comprehensive Cancer Network® [online]. Available from URL [Accessed 2010 Dec 7]
    • National Comprehensive Cancer Network®. NCCN clinical practice guidelines in oncology: acute myeloid leukemia (V.2.2011) [online]. Available from URL: http://www. nccn.org/professionals/physician-gls/PDF/aml.pdf [Accessed 2010 Dec 7].
    • NCCN Clinical Practice Guidelines in Oncology: Acute Myeloid Leukemia (V.2.2011)
  • 8
    • 68949207957 scopus 로고    scopus 로고
    • The incidence of and mortality from leukaemias in the UK: A general population-based study
    • Jul
    • Bhayat F, Das-Gupta E, Smith C, et al. The incidence of and mortality from leukaemias in the UK: a general population-based study. BMC Cancer 2009 Jul 26; 9: 252.
    • (2009) BMC Cancer , vol.26 , Issue.9 , pp. 252
    • Bhayat, F.1    Das-Gupta, E.2    Smith, C.3
  • 10
    • 33750148809 scopus 로고    scopus 로고
    • Guidelines on the management of acute myeloid leukaemia in adults: British Committee for Standards in Haematology
    • Nov
    • Milligan DW, Grimwade D, Cullis JO, et al. Guidelines on the management of acute myeloid leukaemia in adults: British Committee for Standards in Haematology. Br J Haematol 2006 Nov; 135 (4): 450-74.
    • (2006) Br J Haematol , vol.135 , Issue.4 , pp. 450-74
    • Milligan, D.W.1    Grimwade, D.2    Cullis, J.O.3
  • 11
    • 42149096533 scopus 로고    scopus 로고
    • Improvement in survival of adults diagnosed with acute myeloblastic leukemia in the early 21st century
    • Apr
    • Pulte D, Gondos A, Brenner H. Improvement in survival of adults diagnosed with acute myeloblastic leukemia in the early 21st century. Haematologica 2008 Apr; 93 (4): 594-600.
    • (2008) Haematologica , vol.93 , Issue.4 , pp. 594-600
    • Pulte, D.1    Gondos, A.2    Brenner, H.3
  • 12
    • 77954317788 scopus 로고    scopus 로고
    • Acute myeloblastic leukaemias and myelodysplastic syndromes in adult patients: ESMO clinical practice guidelines for diagnosis, treatment and follow-up
    • ESMO Guidelines Working Group May
    • Fey MF, Dreyling M. Acute myeloblastic leukaemias and myelodysplastic syndromes in adult patients: ESMO clinical practice guidelines for diagnosis, treatment and follow-up. ESMO Guidelines Working Group. Ann Oncol 2010 May; 21 Suppl. 5: v158-61.
    • (2010) Ann Oncol , vol.21 , Issue.SUPPL. 5
    • Fey, M.F.1    Dreyling, M.2
  • 14
    • 74549195798 scopus 로고    scopus 로고
    • Current and emerging therapies for acute myeloid leukemia
    • Robak T, Wierzbowska A. Current and emerging therapies for acute myeloid leukemia. Clin Ther 2009; 31 Pt 2:2349-70.
    • (2009) Clin Ther , vol.31 , Issue.PART 2 , pp. 2349-70
    • Robak, T.1    Wierzbowska, A.2
  • 15
    • 71849109098 scopus 로고    scopus 로고
    • Is there a role for maintenance therapy in acute myeloid leukaemia?
    • Dec
    • Baer MR. Is there a role for maintenance therapy in acute myeloid leukaemia? Best Pract Res Clin Haematol 2009 Dec; 22 (4): 517-21.
    • (2009) Best Pract Res Clin Haematol , vol.22 , Issue.4 , pp. 517-21
    • Baer, M.R.1
  • 16
    • 1542753559 scopus 로고    scopus 로고
    • Revised recommendations of the International Working Group for Diagnosis, Standardization of Response Criteria, Treatment Outcomes, and Reporting Standards for Therapeutic Trials in Acute Myeloid Leukemia
    • [published erratum appears in J Clin Oncol 2004 Feb 1; 22 (3) 576] Dec 15
    • Cheson BD, Bennett JM, Kopecky KJ, et al. Revised recommendations of the International Working Group for Diagnosis, Standardization of Response Criteria, Treatment Outcomes, and Reporting Standards for Therapeutic Trials in Acute Myeloid Leukemia [published erratum appears in J Clin Oncol 2004 Feb 1; 22 (3): 576]. J Clin Oncol 2003 Dec 15; 21 (24): 4642-9.
    • (2003) J Clin Oncol , vol.21 , Issue.24 , pp. 4642-9
    • Cheson, B.D.1    Bennett, J.M.2    Kopecky, K.J.3
  • 17
    • 77449159028 scopus 로고    scopus 로고
    • Diagnosis and man-agement of acute myeloid leukemia in adults: Recommendations from an international expert panel on behalf of the European LeukemiaNet
    • Jan 21
    • Dohner H, Estey EH, Amadori S, et al. Diagnosis and man-agement of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet. Blood 2010 Jan 21; 115 (3): 453-74.
    • (2010) Blood , vol.115 , Issue.3 , pp. 453-74
    • Dohner, H.1    Estey, E.H.2    Amadori, S.3
  • 18
    • 62249220561 scopus 로고    scopus 로고
    • Novel postremission strategies in adults with acute myeloid leukemia
    • Lancet JE, Karp JE. Novel postremission strategies in adults with acute myeloid leukemia. Curr Opin Hematol 2009; 16 (2): 105-11.
    • (2009) Curr Opin Hematol , vol.16 , Issue.2 , pp. 105-11
    • Lancet, J.E.1    Karp, J.E.2
  • 19
    • 16644377907 scopus 로고    scopus 로고
    • Interleukin-2 therapy of cancer
    • Bubenk J. Interleukin-2 therapy of cancer. Folia Biol (Praha) 2004; 50 (3-4): 120-30.
    • (2004) Folia Biol (Praha) , vol.50 , Issue.3-4 , pp. 120-30
    • Bubenk, J.1
  • 20
    • 77955641524 scopus 로고    scopus 로고
    • Immunotherapy with histamine dihydrochloride for the prevention of relapse in acute myeloid leukemia
    • Aug
    • Martner A, Thoren FB, Aurelius J, et al. Immunotherapy with histamine dihydrochloride for the prevention of relapse in acute myeloid leukemia. Exp Rev Hematol 2010 Aug; 3 (4): 381-97.
    • (2010) Exp Rev Hematol , vol.3 , Issue.4 , pp. 381-97
    • Martner, A.1    Thoren, F.B.2    Aurelius, J.3
  • 21
    • 50049084370 scopus 로고    scopus 로고
    • Understanding and harnessing the graft-versus-leukaemia effect
    • Sep
    • Barrett AJ. Understanding and harnessing the graft-versus-leukaemia effect. Br J Haematol 2008 Sep; 142 (6): 877-88.
    • (2008) Br J Haematol , vol.142 , Issue.6 , pp. 877-88
    • Barrett, A.J.1
  • 22
    • 33746547247 scopus 로고    scopus 로고
    • The biology of interleukin-2 and interleu-kin-15: Implications for cancer therapy and vaccine design
    • Aug
    • Waldmann TA. The biology of interleukin-2 and interleu-kin-15: implications for cancer therapy and vaccine design. Nat Rev Immunol 2006 Aug; 6 (8): 595-601.
    • (2006) Nat Rev Immunol , vol.6 , Issue.8 , pp. 595-601
    • Waldmann, T.A.1
  • 23
    • 8344239652 scopus 로고    scopus 로고
    • A review of recent findings involving interleukin-2-based cancer therapy
    • Nov
    • Eklund JW, KuzelTM. A review of recent findings involving interleukin-2-based cancer therapy. Curr Opin Oncol 2004 Nov; 16 (6): 542-6.
    • (2004) Curr Opin Oncol , vol.16 , Issue.6 , pp. 542-6
    • Eklund, J.W.1    Kuzel, T.M.2
  • 24
    • 78650936280 scopus 로고    scopus 로고
    • Novartis Pharmaceuticals Corporation [online]. Available from URL [Accessed 2010 Dec 7]
    • Novartis Pharmaceuticals Corporation. Proleukin® (alde-sleukin): US prescribing information [online]. Available from URL: http://www.proleukin.com/ assets/pdf/proleukin. pdf [Accessed 2010 Dec 7].
    • Proleukin® (Alde-sleukin): US Prescribing Information
  • 26
    • 0034114681 scopus 로고    scopus 로고
    • Randomized study of recombinant interleukin-2 after autologous bone marrow transplantation for acute leukemia in first complete remission
    • Mar
    • Blaise D, Attal M, Reiffers J, et al. Randomized study of recombinant interleukin-2 after autologous bone marrow transplantation for acute leukemia in first complete remission. Eur Cytokine Netw 2000 Mar; 11 (1): 91-8.
    • (2000) Eur Cytokine Netw , vol.11 , Issue.1 , pp. 91-8
    • Blaise, D.1    Attal, M.2    Reiffers, J.3
  • 27
    • 53649104968 scopus 로고    scopus 로고
    • Phase III trial of immunotherapy with recombinant interleukin-2 (rIL-2) versus observation in patients <60 years with acute myeloid leukemia (AML) in first remission (CR1): Preliminary results from Cancer and Leukemia Group B (CALGB) 19808 [abstract no. 157]
    • Nov 16
    • Kolitz JE, Hars V, DeAngelo DJ, et al. Phase III trial of immunotherapy with recombinant interleukin-2 (rIL-2) versus observation in patients <60 years with acute myeloid leukemia (AML) in first remission (CR1): preliminary results from Cancer and Leukemia Group B (CALGB) 19808 [abstract no. 157]. Blood 2007 Nov 16; 110 (11): e157.
    • (2007) Blood , vol.110 , Issue.11
    • Kolitz, J.E.1    Hars, V.2    Deangelo, D.J.3
  • 28
    • 38949185746 scopus 로고    scopus 로고
    • Outcomes in CCG-2961, a children's oncology group phase 3 trial for untreated pediatric acute myeloid leukemia: A report from the Children's Oncology Group
    • Feb1
    • Lange BJ, Smith FO, Feusner J, et al. Outcomes in CCG-2961, a children's oncology group phase 3 trial for untreated pediatric acute myeloid leukemia: a report from the Children's Oncology Group. Blood 2008 Feb 1; 111 (3): 1044-53.
    • (2008) Blood , vol.111 , Issue.3 , pp. 1044-53
    • Lange, B.J.1    Smith, F.O.2    Feusner, J.3
  • 29
    • 54449095992 scopus 로고    scopus 로고
    • Low-dose inter-leukin-2 immunotherapy does not improve outcome of patients age 60 years and older with acute myeloid leuke-mia in first complete remission: Cancer and Leukemia Group B Study 9720
    • Oct 20
    • Baer MR, George SL, Caligiuri MA, et al. Low-dose inter-leukin-2 immunotherapy does not improve outcome of patients age 60 years and older with acute myeloid leuke-mia in first complete remission: Cancer and Leukemia Group B Study 9720. J Clin Oncol 2008 Oct 20; 26 (30): 4934-9.
    • (2008) J Clin Oncol , vol.26 , Issue.30 , pp. 4934-9
    • Baer, M.R.1    George, S.L.2    Caligiuri, M.A.3
  • 30
    • 77649202987 scopus 로고    scopus 로고
    • Randomized study of intensified anthracycline doses for induction and recom-binant interleukin-2 for maintenance in patients with acute myeloid leukemia age 50 to 70 years: Results of the ALFA-9801 study
    • Feb 10
    • Pautas C, Merabet F, Thomas X, et al. Randomized study of intensified anthracycline doses for induction and recom-binant interleukin-2 for maintenance in patients with acute myeloid leukemia age 50 to 70 years: results of the ALFA-9801 study. J Clin Oncol 2010 Feb 10; 28 (5): 808-14.
    • (2010) J Clin Oncol , vol.28 , Issue.5 , pp. 808-14
    • Pautas, C.1    Merabet, F.2    Thomas, X.3
  • 31
    • 0036269848 scopus 로고    scopus 로고
    • Histamine in cancer immunotherapy: A pre-clinical background
    • Jun
    • Hellstrand K. Histamine in cancer immunotherapy: a pre-clinical background. Semin Oncol 2002 Jun; 29 (3 Suppl. 7): 35-40.
    • (2002) Semin Oncol , vol.29 , Issue.3 SUPPL. 7 , pp. 35-40
    • Hellstrand, K.1
  • 32
    • 4944244259 scopus 로고    scopus 로고
    • Mechanisms reg-ulating the recruitment of macrophages into hypoxic areas of tumors and other ischemic tissues
    • Oct 15
    • Murdoch C, Giannoudis A, Lewis CE. Mechanisms reg-ulating the recruitment of macrophages into hypoxic areas of tumors and other ischemic tissues. Blood 2004 Oct 15; 104 (8): 2224-34.
    • (2004) Blood , vol.104 , Issue.8 , pp. 2224-34
    • Murdoch, C.1    Giannoudis, A.2    Lewis, C.E.3
  • 33
    • 69149088197 scopus 로고    scopus 로고
    • Post-consolidation immunotherapy with histamine dihydrochloride and interleukin-2 in AML
    • Sep
    • Romero AI, Thoren FB, Aurelius J, et al. Post-consolidation immunotherapy with histamine dihydrochloride and interleukin-2 in AML. Scand J Immunol 2009 Sep; 70 (3): 194-205.
    • (2009) Scand J Immunol , vol.70 , Issue.3 , pp. 194-205
    • Romero, A.I.1    Thoren, F.B.2    Aurelius, J.3
  • 34
    • 78650939174 scopus 로고    scopus 로고
    • EpiCept GmbH [online]. Available from URL [Accessed 2010 Dec 7]
    • EpiCept GmbH. Ceplene 0.5 mg/0.5 mL solution for injec-tion: summary of product characteristics [online]. Available from URL: http://www.ema.europa.eu/ docs/en-GB/ document-library/EPAR-Product-Information/human/ 000796/WC500023116.pdf [Accessed 2010 Dec 7].
    • Ceplene 0.5 mg/0.5 ML Solution for Injec-tion: Summary of Product Characteristics
  • 35
    • 78650941185 scopus 로고    scopus 로고
    • [online]. Available from URL [Accessed 2010 Dec 7]
    • European Medicines Agency. Ceplene: European public as-sessment report [online]. Available from URL: http://www. ema.europa.eu/docs/en-GB/document- library/EPAR-Public-assessment-report/human/000796/WC500023115. pdf [Accessed 2010 Dec 7].
    • Ceplene: European Public As-sessment Report
  • 36
    • 72449183606 scopus 로고    scopus 로고
    • Histamine, histamine recep-tors and their role in immune pathology
    • Dec
    • Jutel M, Akdis M, Akdis CA. Histamine, histamine recep-tors and their role in immune pathology. Clin Exp Allergy 2009 Dec; 39 (12): 1786-800.
    • (2009) Clin Exp Allergy , vol.39 , Issue.12 , pp. 1786-800
    • Jutel, M.1    Akdis, M.2    Akdis, C.A.3
  • 37
    • 0029829358 scopus 로고    scopus 로고
    • NK cell-medi-ated killing of AML blasts: Role of histamine, monocytes and reactive oxygen metabolites
    • Oct
    • Brune M, Hansson M, Mellqvist UH, et al. NK cell-medi-ated killing of AML blasts: role of histamine, monocytes and reactive oxygen metabolites. Eur J Haematol 1996 Oct; 57 (4): 312-9.
    • (1996) Eur J Haematol , vol.57 , Issue.4 , pp. 312-9
    • Brune, M.1    Hansson, M.2    Mellqvist, U.H.3
  • 38
    • 0022555477 scopus 로고
    • Histamine H2-receptor-mediated regulation of human natural killer cell activity
    • Jul 15
    • Hellstrand K, Hermodsson S. Histamine H2-receptor-mediated regulation of human natural killer cell activity. J Immunol 1986 Jul 15; 137 (2): 656-60.
    • (1986) J Immunol , vol.137 , Issue.2 , pp. 656-60
    • Hellstrand, K.1    Hermodsson, S.2
  • 39
    • 0028113354 scopus 로고
    • Histaminergic regulation of NK cells: Role of monocyte-derived reactive oxygen metabolites
    • Dec 1
    • Hellstrand K, Asea A, Dahlgren C, et al. Histaminergic regulation of NK cells: role of monocyte-derived reactive oxygen metabolites. J Immunol 1994 Dec 1; 153 (11): 4940-7.
    • (1994) J Immunol , vol.153 , Issue.11 , pp. 4940-7
    • Hellstrand, K.1    Asea, A.2    Dahlgren, C.3
  • 40
    • 0025614624 scopus 로고
    • Role of histamine in natural killer cell-mediated resistance against tumor cells
    • Dec 15
    • Hellstrand K, Asea A, Hermodsson S. Role of histamine in natural killer cell-mediated resistance against tumor cells. J Immunol 1990 Dec 15; 145 (12): 4365-70.
    • (1990) J Immunol , vol.145 , Issue.12 , pp. 4365-70
    • Hellstrand, K.1    Asea, A.2    Hermodsson, S.3
  • 41
    • 0030027630 scopus 로고    scopus 로고
    • Histaminergic reg-ulation of natural killer cell-mediated clearance of tumour cells in mice
    • Jan
    • Asea A, Hermodsson S, Hellstrand K. Histaminergic reg-ulation of natural killer cell-mediated clearance of tumour cells in mice. Scand J Immunol 1996 Jan; 43 (1): 9-15.
    • (1996) Scand J Immunol , vol.43 , Issue.1 , pp. 9-15
    • Asea, A.1    Hermodsson, S.2    Hellstrand, K.3
  • 42
    • 0031910649 scopus 로고    scopus 로고
    • The response of Dunning R3327 prostatic adenocarcinoma to IL-2, hista-mine and radiation
    • Apr
    • Johansson S, Landstrom M, Hellstrand K, et al. The response of Dunning R3327 prostatic adenocarcinoma to IL-2, hista-mine and radiation. Br J Cancer 1998 Apr; 77 (8): 1213-9.
    • (1998) Br J Cancer , vol.77 , Issue.8 , pp. 1213-9
    • Johansson, S.1    Landstrom, M.2    Hellstrand, K.3
  • 43
    • 0029980720 scopus 로고    scopus 로고
    • Remission maintenance therapy with histamine and interleukin-2 in acute myelogenous leukaemia
    • Mar
    • Brune M, Hellstrand K. Remission maintenance therapy with histamine and interleukin-2 in acute myelogenous leukaemia. Br J Haematol 1996 Mar; 92 (3): 620-6.
    • (1996) Br J Haematol , vol.92 , Issue.3 , pp. 620-6
    • Brune, M.1    Hellstrand, K.2
  • 44
    • 0031441799 scopus 로고    scopus 로고
    • Histamine and interleukin-2 in acute myelogenous leukemia
    • Nov
    • Hellstrand K, Mellqvist U-H, Wallhult E, et al. Histamine and interleukin-2 in acute myelogenous leukemia. Leuk Lymphoma 1997 Nov; 27 (5-6): 429-38.
    • (1997) Leuk Lymphoma , vol.27 , Issue.5-6 , pp. 429-38
    • Hellstrand, K.1    Mellqvist, U.-H.2    Wallhult, E.3
  • 45
    • 33745714215 scopus 로고    scopus 로고
    • Improved leukemia-free survival after postconsolidation immunotherapy with histamine dihydrochloride and interleukin-2 in acute mye-loid leukemia: Results of a randomized phase 3 trial
    • Jul 1
    • Brune M, Castaigne S, Catalano J, et al. Improved leukemia-free survival after postconsolidation immunotherapy with histamine dihydrochloride and interleukin-2 in acute mye-loid leukemia: results of a randomized phase 3 trial. Blood 2006 Jul 1; 108 (1): 88-96.
    • (2006) Blood , vol.108 , Issue.1 , pp. 88-96
    • Brune, M.1    Castaigne, S.2    Catalano, J.3
  • 46
    • 0033661846 scopus 로고    scopus 로고
    • Interleukin-2 in cancer therapy: Uses and optimum management of adverse effects
    • Mekhail T, Wood L, Bukowski R. Interleukin-2 in cancer therapy: uses and optimum management of adverse effects. Biodrugs 2000; 14 (5): 299-318.
    • (2000) Biodrugs , vol.14 , Issue.5 , pp. 299-318
    • Mekhail, T.1    Wood, L.2    Bukowski, R.3
  • 47
    • 0035998755 scopus 로고    scopus 로고
    • Pharmaco-kinetics of histamine dihydrochloride in healthy volunteers and cancer patients: Implications for combined immuno-therapy with interleukin-2
    • Jul
    • Middleton M, Sarno M, Agarwala SS, et al. Pharmaco-kinetics of histamine dihydrochloride in healthy volunteers and cancer patients: implications for combined immuno-therapy with interleukin-2. J Clin Pharmacol 2002 Jul; 42 (7): 774-81.
    • (2002) J Clin Pharmacol , vol.42 , Issue.7 , pp. 774-81
    • Middleton, M.1    Sarno, M.2    Agarwala, S.S.3
  • 48
    • 78650940032 scopus 로고    scopus 로고
    • Post-consolidation immunotherapy with histamine dihydrochloride and interleukin-2 in AML: Long term follow-up of leukemia-free survival and overall survival [abstract no. 1846]
    • Nov 16 Plus poster presented at the American Society of Hematology 49th Annual Meeting and Exposition; 2007 Dec 8-11; Atlanta (GA)
    • Brune ML, Rowe JM, Szer J, et al. Post-consolidation immunotherapy with histamine dihydrochloride and interleukin-2 in AML: long term follow-up of leukemia-free survival and overall survival [abstract no. 1846]. Blood 2007 Nov 16; 110 (11): 1846. Plus poster presented at the American Society of Hematology 49th Annual Meeting and Exposition; 2007 Dec 8-11; Atlanta (GA).
    • (2007) Blood , vol.110 , Issue.11 , pp. 1846
    • Brune, M.L.1    Rowe, J.M.2    Szer, J.3
  • 49
    • 78650964183 scopus 로고    scopus 로고
    • Six-year outcomes update from a randomized phase 3 trial in AML: Durable effect of remission maintenance immunotherapy with his-tamine dihydrochloride and low-dose IL-2 [abstract no. 0845]
    • Jun
    • Brune L, Rowe JM, Buyse ME, et al. Six-year outcomes update from a randomized phase 3 trial in AML: durable effect of remission maintenance immunotherapy with his-tamine dihydrochloride and low-dose IL-2 [abstract no. 0845]. Haematologica 2009 Jun; 94 Suppl. 2: 340-1.
    • (2009) Haematologica , vol.94 , Issue.SUPPL. 2 , pp. 340-1
    • Brune, L.1    Rowe, J.M.2    Buyse, M.E.3
  • 50
    • 78650937136 scopus 로고    scopus 로고
    • Leukemia-free sur-vival (LFS) as a surrogate for overall survival (OS) in AML patients in remission: A trial of a novel immunotherapy with histamine dihydrochloride plus low-dose IL-2 (HDC/IL-2) [abstract no. 0519]
    • Jul Plus poster presented at the 13th Congress of the European Hematology Association; 2008 Jun 12-15; Copenhagen
    • Buyse ME, Squifflet P, Allard SE, et al. Leukemia-free sur-vival (LFS) as a surrogate for overall survival (OS) in AML patients in remission: a trial of a novel immunotherapy with histamine dihydrochloride plus low-dose IL-2 (HDC/IL-2) [abstract no. 0519]. Haematologica 2008 Jul; 93 Suppl. 1: 209-10. Plus poster presented at the 13th Congress of the European Hematology Association; 2008 Jun 12-15; Copenhagen.
    • (2008) Haematologica , vol.93 , Issue.SUPPL. 1 , pp. 209-10
    • Buyse, M.E.1    Squifflet, P.2    Allard, S.E.3
  • 51
    • 78650943715 scopus 로고    scopus 로고
    • Quality-of-life during remission maintenance immunotherapy in AML: A prospective assessment using EORTC QLQ-C30 in a randomized trial of histamine dihydrochloride plus low-dose IL-2 (HDC/IL-2) [abstract no. 0794]
    • Jul Plus poster presented at the 13th Congress of the European Hematology Association; 2008 Jun 12-15; Copenhagen
    • Wallhult A, Whisnant K, Nilsson I, et al. Quality-of-life during remission maintenance immunotherapy in AML: a prospective assessment using EORTC QLQ-C30 in a randomized trial of histamine dihydrochloride plus low-dose IL-2 (HDC/IL-2) [abstract no. 0794]. Haematologica 2008 Jul; 93 Suppl. 1: 316-7. Plus poster presented at the 13th Congress of the European Hematology Association; 2008 Jun 12-15; Copenhagen.
    • (2008) Haematologica , vol.93 , Issue.SUPPL. 1 , pp. 316-7
    • Wallhult, A.1    Whisnant, K.2    Nilsson, I.3
  • 52
    • 0037114753 scopus 로고    scopus 로고
    • Pretreatment cyto-genetic abnormalities are predictive of induction success cumulative incidence of relapse and overall survival in adult patients with de novo acute myeloid leukemia: Results from Cancer and Leukemia Group B (CALGB 8461)
    • Dec 15
    • Byrd JC, Mrozek K, Dodge RK, et al. Pretreatment cyto-genetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B (CALGB 8461). Blood 2002 Dec 15; 100 (13): 4325-36.
    • (2002) Blood , vol.100 , Issue.13 , pp. 4325-36
    • Byrd, J.C.1    Mrozek, K.2    Dodge, R.K.3
  • 53
    • 1542753653 scopus 로고    scopus 로고
    • 6-Thioguanine, cytarabine, and daunorubicin (TAD) and high-dose cy-tarabine and mitoxantrone (HAM) for induction, TAD for consolidation, and either prolonged maintenance by reduced monthly TAD or TAD-HAM-TAD and once course of intensive consolidation by sequential HAM in adult patients at all ages with de novo acute myeloid leukemia: A randomized trial of the German AML Cooperative Group
    • Dec 15
    • Buchner T, Hiddemann W, Berdel WE, et al. 6-Thioguanine, cytarabine, and daunorubicin (TAD) and high-dose cy-tarabine and mitoxantrone (HAM) for induction, TAD for consolidation, and either prolonged maintenance by reduced monthly TAD or TAD-HAM-TAD and once course of intensive consolidation by sequential HAM in adult patients at all ages with de novo acute myeloid leukemia: a randomized trial of the German AML Cooperative Group. J Clin Oncol 2003 Dec 15; 21 (24): 4496-504.
    • (2003) J Clin Oncol , vol.21 , Issue.24 , pp. 4496-504
    • Buchner, T.1    Hiddemann, W.2    Berdel, W.E.3
  • 54
    • 33745191374 scopus 로고    scopus 로고
    • Pretreatment cyto-genetics add to other prognostic factors predicting complete remission and long-term outcome in patients 60 years or older with acute myeloid leukemia: Results from Cancer and Leukemia Group B 8461
    • Jul 1
    • Farag SS, Archer KJ, Mrozek K, et al. Pretreatment cyto-genetics add to other prognostic factors predicting complete remission and long-term outcome in patients 60 years or older with acute myeloid leukemia: results from Cancer and Leukemia Group B 8461. Blood 2006 Jul 1; 108 (1): 63-73.
    • (2006) Blood , vol.108 , Issue.1 , pp. 63-73
    • Farag, S.S.1    Archer, K.J.2    Mrozek, K.3
  • 57
    • 77954635822 scopus 로고    scopus 로고
    • Immunotherapy prospects for acute myeloid leukaemia
    • Aug
    • Barrett AJ, Le Blanc K. Immunotherapy prospects for acute myeloid leukaemia. Clin Exp Immunol 2010 Aug; 161 (2): 223-32.
    • (2010) Clin Exp Immunol , vol.161 , Issue.2 , pp. 223-32
    • Barrett, A.J.1    Le Blanc, K.2
  • 58
    • 0032764432 scopus 로고    scopus 로고
    • Use of interleukin-2 in the management of haematological malignancies: Focus on minimal residual disease
    • Mandelli F, Capria S, Vignetti M, et al. Use of interleukin-2 in the management of haematological malignancies: focus on minimal residual disease. Biodrugs 1999; 12 (1): 43-53.
    • (1999) Biodrugs , vol.12 , Issue.1 , pp. 43-53
    • Mandelli, F.1    Capria, S.2    Vignetti, M.3
  • 59
    • 78650932963 scopus 로고    scopus 로고
    • Cost-effectiveness analysis of histamine dihydrochloride +low dose interleu-kin-2 vs standard of care for acute myeloid leukemia patients in their first complete remission: A UK perspective [abstract no. PCN83]
    • Oct Plus poster presented at the 12th Annual European Congress of the International Society for Pharmacoeconomics and Outcomes Research; 2009 Oct 24-27; Paris
    • Magar RS, Purdy C, Hayward A, et al. Cost-effectiveness analysis of histamine dihydrochloride +low dose interleu-kin-2 vs standard of care for acute myeloid leukemia patients in their first complete remission: a UK perspective [abstract no. PCN83]. Value Health 2009 Oct; 12 (7): A272. Plus poster presented at the 12th Annual European Congress of the International Society for Pharmacoeconomics and Outcomes Research; 2009 Oct 24-27; Paris
    • (2009) Value Health , vol.12 , Issue.7
    • Magar, R.S.1    Purdy, C.2    Hayward, A.3


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