Genomic rearrangements induced by unscheduled DNA double strand breaks in somatic mammalian cells

FEBS Journal

Volumn 284, Issue 15, 2017, Pages 2324-2344

  So, Ayeong ^a   Le Guen, Tangui ^a   Lopez, Bernard S ^a   Guirouilh Barbat, Josée ^a  

^a INSTITUT GUSTAVE ROUSSY   (France)

Author keywords

double strand break; double strand break repair; genome instability; genome rearrangements; homologous recombination; non homologous end joining

Indexed keywords

ENDONUCLEASE;

CHROMOTHRIPSIS; DNA CLEAVAGE; DNA END JOINING REPAIR; DNA REPLICATION; DNA SYNTHESIS; DNA TEMPLATE; DOUBLE STRANDED DNA BREAK; GENE INSERTION; GENE REARRANGEMENT; GENE SWITCHING; GENOME ANALYSIS; GENOMIC INSTABILITY; HOMOLOGOUS RECOMBINATION; HUMAN; IMMUNE SYSTEM; MAMMAL CELL; MEIOSIS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RETROPOSON; REVERSE TRANSCRIPTION; REVIEW; SOMATIC CELL; TELOMERE; ANIMAL; BIOLOGICAL MODEL; DNA REPAIR; PHYSIOLOGICAL STRESS; RECOMBINATION REPAIR; UPREGULATION;

ANIMALS; CHROMOTHRIPSIS; DNA BREAKS, DOUBLE-STRANDED; DNA END-JOINING REPAIR; DNA REPAIR; GENE REARRANGEMENT; GENOMIC INSTABILITY; HUMANS; MODELS, GENETIC; OXIDATIVE STRESS; RECOMBINATIONAL DNA REPAIR; STRESS, PHYSIOLOGICAL; UP-REGULATION;

EID: 85016557118     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.14053     Document Type: Review

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