Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells

Genes and Development

Volumn 15, Issue 24, 2001, Pages 3237-3242

  Pierce, A J ^a   Hu, P ^a   Han, M ^a   Ellis, N ^a   Jasin, M ^a  

^a Weill Cornell Medical Center   (United States)

Author keywords

DNA double strand break; DNA PK; Gene targeting; Homologous recombination; Ku protein; Nonhomologous end joining; Sister chromatid exchange

Indexed keywords

DNA FRAGMENT; DOUBLE STRANDED DNA; KU ANTIGEN;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING KINETICS; BINDING SITE; CHROMATID EXCHANGE; CONTROLLED STUDY; DNA REPAIR; DNA STRAND BREAKAGE; GENE FREQUENCY; GENE MUTATION; GENE TARGETING; GENETIC TRANSFECTION; MAMMAL CELL; MODULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; SISTER CHROMATID;

ANIMALS; ANTIGENS, NUCLEAR; CELL LINE; CLONING, MOLECULAR; DNA; DNA DAMAGE; DNA HELICASES; DNA PRIMERS; DNA REPAIR; DNA-ACTIVATED PROTEIN KINASE; DNA-BINDING PROTEINS; GENE TARGETING; HUMANS; MICE; MICE, KNOCKOUT; MUTATION; NUCLEAR PROTEINS; POLYMERASE CHAIN REACTION; RECOMBINATION, GENETIC; SISTER CHROMATID EXCHANGE; TRANSCRIPTION FACTORS;

ANIMALIA; MAMMALIA;

EID: 0035893363     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.946401     Document Type: Article

References (31)

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4. The importance of repairing stalled replication forks
5. Control of crossing over
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8. Homologous and non-homologous recombination differentially affect DNA damage repair in mice
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15. Mechanism and control of meiotic recombination initiation
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20. 2/M arrest
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