A microhomology-mediated break-induced replication model for the origin of human copy number variation

PLoS Genetics

Volumn 5, Issue 1, 2009, Pages

  Hastings, P J ^a   Ira, Grzegorz ^a   Lupski, James R ^a,b  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b TEXAS CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

OLIGONUCLEOTIDE; PROTEOLIPID PROTEIN; PROTEOLIPID PROTEIN 1; SINGLE STRANDED DNA; UNCLASSIFIED DRUG;

CHROMOSOME STRUCTURE; COMPARATIVE GENOMIC HYBRIDIZATION; COMPUTER MODEL; DNA REPAIR; DNA STRAND BREAKAGE; DROSOPHILA; ESCHERICHIA COLI; GENE DELETION; GENE DUPLICATION; GENE NUMBER; GENE REARRANGEMENT; GENE REPLICATION; GENETIC VARIABILITY; GENOMICS; HUMAN; MICROHOMOLOGY MEDIATED BREAK INDUCED REPLICATION; NEOPLASM; NONHUMAN; PELIZAEUS MERZBACHER DISEASE; POLYMERIZATION; REVIEW; YEAST; ANIMAL; BIOLOGICAL MODEL; DNA REPLICATION; GENE DOSAGE; GENETIC RECOMBINATION; GENETICS; SEQUENCE HOMOLOGY; SINGLE STRANDED DNA BREAK;

ANIMALS; DNA BREAKS, SINGLE-STRANDED; DNA REPLICATION; ESCHERICHIA COLI; GENE DOSAGE; GENE REARRANGEMENT; HUMANS; MODELS, GENETIC; NEOPLASMS; RECOMBINATION, GENETIC; SEQUENCE HOMOLOGY; YEASTS;

EID: 59249105978     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1000327     Document Type: Review

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