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Volumn 145, Issue 3, 2011, Pages 435-446

Nucleotide deficiency promotes genomic instability in early stages of cancer development

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN E; NUCLEOSIDE; NUCLEOTIDE; PROTEIN E6; PROTEIN E7; TRANSCRIPTION FACTOR E2F;

EID: 79955525482     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cell.2011.03.044     Document Type: Article
Times cited : (647)

References (50)
  • 1
    • 1542751717 scopus 로고    scopus 로고
    • Cyclin e and its low molecular weight forms in human cancer and as targets for cancer therapy
    • S. Akli, and K. Keyomarsi Cyclin E and its low molecular weight forms in human cancer and as targets for cancer therapy Cancer Biol. Ther. 2 4, Suppl 1 2003 S38 S47
    • (2003) Cancer Biol. Ther. , vol.2 , Issue.4 SUPPL. 1
    • Akli, S.1    Keyomarsi, K.2
  • 2
    • 0042743766 scopus 로고    scopus 로고
    • Dynamics of DNA replication in mammalian somatic cells: Nucleotide pool modulates origin choice and interorigin spacing
    • DOI 10.1016/S0092-8674(03)00569-5
    • M. Anglana, F. Apiou, A. Bensimon, and M. Debatisse Dynamics of DNA replication in mammalian somatic cells: nucleotide pool modulates origin choice and interorigin spacing Cell 114 2003 385 394 (Pubitemid 36962936)
    • (2003) Cell , vol.114 , Issue.3 , pp. 385-394
    • Anglana, M.1    Apiou, F.2    Bensimon, A.3    Debatisse, M.4
  • 6
    • 34547814092 scopus 로고    scopus 로고
    • Replication fork velocities at adjacent replication origins are coordinately modified during DNA replication in human cells
    • DOI 10.1091/mbc.E06-08-0689
    • C. Conti, B. Sacc, J. Herrick, C. Lalou, Y. Pommier, and A. Bensimon Replication fork velocities at adjacent replication origins are coordinately modified during DNA replication in human cells Mol. Biol. Cell 18 2007 3059 3067 (Pubitemid 47235311)
    • (2007) Molecular Biology of the Cell , vol.18 , Issue.8 , pp. 3059-3067
    • Conti, C.1    Sacca, B.2    Herrick, J.3    Lalou, C.4    Pommier, Y.5    Bensimon, A.6
  • 7
    • 0032132806 scopus 로고    scopus 로고
    • A new role for hypoxia in tumor progression: Induction of fragile site triggering genomic rearrangements and formation of complex DMs and HSRs
    • A. Coquelle, F. Toledo, S. Stern, A. Bieth, and M. Debatisse A new role for hypoxia in tumor progression: induction of fragile site triggering genomic rearrangements and formation of complex DMs and HSRs Mol. Cell 2 1998 259 265 (Pubitemid 128373652)
    • (1998) Molecular Cell , vol.2 , Issue.2 , pp. 259-265
    • Coquelle, A.1    Toledo, F.2    Stern, S.3    Bieth, A.4    Debatisse, M.5
  • 8
    • 52949092763 scopus 로고    scopus 로고
    • Replication fork movement sets chromatin loop size and origin choice in mammalian cells
    • S. Courbet, S. Gay, N. Arnoult, G. Wronka, M. Anglana, O. Brison, and M. Debatisse Replication fork movement sets chromatin loop size and origin choice in mammalian cells Nature 455 2008 557 560
    • (2008) Nature , vol.455 , pp. 557-560
    • Courbet, S.1    Gay, S.2    Arnoult, N.3    Wronka, G.4    Anglana, M.5    Brison, O.6    Debatisse, M.7
  • 10
    • 0036897282 scopus 로고    scopus 로고
    • The human papillomavirus type 16 E6 and E7 oncoproteins independently induce numerical and structural chromosome instability
    • S. Duensing, and K. Münger The human papillomavirus type 16 E6 and E7 oncoproteins independently induce numerical and structural chromosome instability Cancer Res. 62 2002 7075 7082 (Pubitemid 35424103)
    • (2002) Cancer Research , vol.62 , Issue.23 , pp. 7075-7082
    • Duensing, S.1    Munger, K.2
  • 11
    • 10744229405 scopus 로고    scopus 로고
    • Centrosomes, genomic instability, and cervical carcinogenesis
    • DOI 10.1615/CritRevEukaryotGeneExpr.v13.i1.20
    • S. Duensing, and K. Münger Centrosomes, genomic instability, and cervical carcinogenesis Crit. Rev. Eukaryot. Gene Expr. 13 2003 9 23 (Pubitemid 36834693)
    • (2003) Critical Reviews in Eukaryotic Gene Expression , vol.13 , Issue.1 , pp. 9-23
    • Duensing, S.1    Munger, K.2
  • 12
    • 1242319406 scopus 로고    scopus 로고
    • Mechanisms of genomic instability in human cancer: Insights from studies with human papillomavirus oncoproteins
    • DOI 10.1002/ijc.11691
    • S. Duensing, and K. Münger Mechanisms of genomic instability in human cancer: insights from studies with human papillomavirus oncoproteins Int. J. Cancer 109 2004 157 162 (Pubitemid 38240914)
    • (2004) International Journal of Cancer , vol.109 , Issue.2 , pp. 157-162
    • Duensing, S.1    Munger, K.2
  • 13
    • 0034730196 scopus 로고    scopus 로고
    • The human papillomavirus type 16 E6 and E7 oncoproteins cooperate to induce mitotic defects and genomic instability by uncoupling centrosome duplication from the cell division cycle
    • S. Duensing, L.Y. Lee, A. Duensing, J. Basile, S. Piboonniyom, S. Gonzalez, C.P. Crum, and K. Munger The human papillomavirus type 16 E6 and E7 oncoproteins cooperate to induce mitotic defects and genomic instability by uncoupling centrosome duplication from the cell division cycle Proc. Natl. Acad. Sci. USA 97 2000 10002 10007
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 10002-10007
    • Duensing, S.1    Lee, L.Y.2    Duensing, A.3    Basile, J.4    Piboonniyom, S.5    Gonzalez, S.6    Crum, C.P.7    Munger, K.8
  • 14
    • 34250721675 scopus 로고    scopus 로고
    • Mismatched nucleotides as the lesions responsible for radiosensitization with gemcitabine: A new paradigm for antimetabolite radiosensitizers
    • DOI 10.1158/1535-7163.MCT-07-0068
    • S.A. Flanagan, B.W. Robinson, C.M. Krokosky, and D.S. Shewach Mismatched nucleotides as the lesions responsible for radiosensitization with gemcitabine: a new paradigm for antimetabolite radiosensitizers Mol. Cancer Ther. 6 2007 1858 1868 (Pubitemid 46954063)
    • (2007) Molecular Cancer Therapeutics , vol.6 , Issue.6 , pp. 1858-1868
    • Flanagan, S.A.1    Robinson, B.W.2    Krokosky, C.M.3    Shewach, D.S.4
  • 15
    • 33744934811 scopus 로고    scopus 로고
    • E2F1 induces MRN foci formation and a cell cycle checkpoint response in human fibroblasts
    • DOI 10.1038/sj.onc.1209352
    • F.M. Frame, H.A. Rogoff, M.T. Pickering, W.D. Cress, and T.F. Kowalik E2F1 induces MRN foci formation and a cell cycle checkpoint response in human fibroblasts Oncogene 25 2006 3258 3266 (Pubitemid 43846310)
    • (2006) Oncogene , vol.25 , Issue.23 , pp. 3258-3266
    • Frame, F.M.1    Rogoff, H.A.2    Pickering, M.T.3    Cress, W.D.4    Kowalik, T.F.5
  • 16
    • 27144516904 scopus 로고    scopus 로고
    • The role of diet and nutrition in cervical carcinogenesis: A review of recent evidence
    • DOI 10.1002/ijc.21193
    • R. García-Closas, X. Castellsagué, X. Bosch, and C.A. González The role of diet and nutrition in cervical carcinogenesis: a review of recent evidence Int. J. Cancer 117 2005 629 637 (Pubitemid 41504551)
    • (2005) International Journal of Cancer , vol.117 , Issue.4 , pp. 629-637
    • Garcia-Closas, R.1    Castellsague, X.2    Bosch, X.3    Gonzalez, C.A.4
  • 17
    • 4143094867 scopus 로고    scopus 로고
    • Global effects of human papillomavirus type 18 E6/E7 in an organotypic keratinocyte culture system
    • DOI 10.1128/JVI.78.17.9041-9050.2004
    • P.A. Garner-Hamrick, J.M. Fostel, W.M. Chien, N.S. Banerjee, L.T. Chow, T.R. Broker, and C. Fisher Global effects of human papillomavirus type 18 E6/E7 in an organotypic keratinocyte culture system J. Virol. 78 2004 9041 9050 (Pubitemid 39096515)
    • (2004) Journal of Virology , vol.78 , Issue.17 , pp. 9041-9050
    • Garner-Hamrick, P.A.1    Fostel, J.M.2    Chien, W.-M.3    Banerjee, N.S.4    Chow, L.T.5    Broker, T.R.6    Fisher, C.7
  • 18
    • 37249025795 scopus 로고    scopus 로고
    • Dormant origins licensed by excess Mcm2-7 are required for human cells to survive replicative stress
    • DOI 10.1101/gad.457807
    • X.Q. Ge, D.A. Jackson, and J.J. Blow Dormant origins licensed by excess Mcm2-7 are required for human cells to survive replicative stress Genes Dev. 21 2007 3331 3341 (Pubitemid 350277759)
    • (2007) Genes and Development , vol.21 , Issue.24 , pp. 3331-3341
    • Ge, X.Q.1    Jackson, D.A.2    Blow, J.J.3
  • 23
    • 40449120350 scopus 로고    scopus 로고
    • An oncogene-induced DNA damage model for cancer development
    • DOI 10.1126/science.1140735
    • T.D. Halazonetis, V.G. Gorgoulis, and J. Bartek An oncogene-induced DNA damage model for cancer development Science 319 2008 1352 1355 (Pubitemid 351354863)
    • (2008) Science , vol.319 , Issue.5868 , pp. 1352-1355
    • Halazonetis, T.D.1    Gorgoulis, V.G.2    Bartek, J.3
  • 24
    • 0037358306 scopus 로고    scopus 로고
    • Comprehensive molecular cytogenetic characterization of cervical cancer cell lines
    • DOI 10.1002/gcc.10158
    • C.P. Harris, X.Y. Lu, G. Narayan, B. Singh, V.V. Murty, and P.H. Rao Comprehensive molecular cytogenetic characterization of cervical cancer cell lines Genes Chromosomes Cancer 36 2003 233 241 (Pubitemid 36158196)
    • (2003) Genes Chromosomes and Cancer , vol.36 , Issue.3 , pp. 233-241
    • Harris, C.P.1    Lu, X.Y.2    Narayan, G.3    Singh, B.4    Murty, V.V.V.S.5    Rao, P.H.6
  • 25
    • 0032752071 scopus 로고    scopus 로고
    • Single molecule analysis of DNA replication
    • DOI 10.1016/S0300-9084(99)00210-2
    • J. Herrick, and A. Bensimon Single molecule analysis of DNA replication Biochimie 81 1999 859 871 (Pubitemid 29520612)
    • (1999) Biochimie , vol.81 , Issue.8-9 , pp. 859-871
    • Herrick, J.1    Bensimon, A.2
  • 26
    • 18344381018 scopus 로고    scopus 로고
    • Cyclin E in normal and neoplastic cell cycles
    • DOI 10.1038/sj.onc.1208613
    • H.C. Hwang, and B.E. Clurman Cyclin E in normal and neoplastic cell cycles Oncogene 24 2005 2776 2786 (Pubitemid 40638089)
    • (2005) Oncogene , vol.24 , Issue.17 , pp. 2776-2786
    • Hwang, H.C.1    Clurman, B.E.2
  • 27
    • 0042166135 scopus 로고    scopus 로고
    • Impaired function of p53R2 in Rrm2b-null mice causes severe renal failure through attenuation of dNTP pools
    • DOI 10.1038/ng1212
    • T. Kimura, S. Takeda, Y. Sagiya, M. Gotoh, Y. Nakamura, and H. Arakawa Impaired function of p53R2 in Rrm2b-null mice causes severe renal failure through attenuation of dNTP pools Nat. Genet. 34 2003 440 445 (Pubitemid 36935338)
    • (2003) Nature Genetics , vol.34 , Issue.4 , pp. 440-445
    • Kimura, T.1    Takeda, S.2    Sagiya, Y.3    Gotoh, M.4    Nakamura, Y.5    Arakawa, H.6
  • 29
    • 0036463384 scopus 로고    scopus 로고
    • The fabric of cancer cell biology - Weaving together the strands
    • DOI 10.1016/S1535-6108(02)00020-X
    • R.D. Klausner The fabric of cancer cell biology-Weaving together the strands Cancer Cell 1 2002 3 10 (Pubitemid 41039168)
    • (2002) Cancer Cell , vol.1 , Issue.1 , pp. 3-10
    • Klausner, R.D.1
  • 30
    • 33845405316 scopus 로고    scopus 로고
    • DNA replication origin interference increases the spacing between initiation events in human cells
    • DOI 10.1091/mbc.E06-04-0298
    • R. Lebofsky, R. Heilig, M. Sonnleitner, J. Weissenbach, and A. Bensimon DNA replication origin interference increases the spacing between initiation events in human cells Mol. Biol. Cell 17 2006 5337 5345 (Pubitemid 44907373)
    • (2006) Molecular Biology of the Cell , vol.17 , Issue.12 , pp. 5337-5345
    • Lebofsky, R.1    Heilig, R.2    Sonnleitner, M.3    Weissenbach, J.4    Bensimon, A.5
  • 34
    • 0027193034 scopus 로고
    • Cyclin-dependent regulation of G1 in mammalian fibroblasts
    • M. Ohtsubo, and J.M. Roberts Cyclin-dependent regulation of G1 in mammalian fibroblasts Science 259 1993 1908 1912
    • (1993) Science , vol.259 , pp. 1908-1912
    • Ohtsubo, M.1    Roberts, J.M.2
  • 35
    • 32244439530 scopus 로고    scopus 로고
    • Rb inactivation leads to E2F1-mediated DNA double-strand break accumulation
    • M.T. Pickering, and T.F. Kowalik Rb inactivation leads to E2F1-mediated DNA double-strand break accumulation Oncogene 25 2006 746 755
    • (2006) Oncogene , vol.25 , pp. 746-755
    • Pickering, M.T.1    Kowalik, T.F.2
  • 36
    • 2442695456 scopus 로고    scopus 로고
    • Telomere erosion and chromosomal instability in cells expressing the HPV oncogene 16E6
    • DOI 10.1038/sj.onc.1207388
    • A.W. Plug-DeMaggio, T. Sundsvold, M.A. Wurscher, J.I. Koop, A.J. Klingelhutz, and J.K. McDougall Telomere erosion and chromosomal instability in cells expressing the HPV oncogene 16E6 Oncogene 23 2004 3561 3571 (Pubitemid 38658422)
    • (2004) Oncogene , vol.23 , Issue.20 , pp. 3561-3571
    • Plug-DeMaggio, A.W.1    Sundsvold, T.2    Wurscher, M.A.3    Koop, J.I.4    Klingelhutz, A.J.5    McBougall, J.K.6
  • 37
    • 0012971192 scopus 로고    scopus 로고
    • Relationship of folate to colorectal and cervical cancer: Review and recommendations for practitioners
    • DOI 10.1016/S0002-8223(02)90281-6
    • G.C. Rampersaud, L.B. Bailey, and G.P. Kauwell Relationship of folate to colorectal and cervical cancer: review and recommendations for practitioners J. Am. Diet. Assoc. 102 2002 1273 1282 (Pubitemid 40434115)
    • (2002) Journal of the American Dietetic Association , vol.102 , Issue.9 , pp. 1273-1282
    • Rampersaud, G.C.1    Bailey, L.B.2    Kauwell, G.P.A.3
  • 38
    • 0032489520 scopus 로고    scopus 로고
    • DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
    • DOI 10.1074/jbc.273.10.5858
    • E.P. Rogakou, D.R. Pilch, A.H. Orr, V.S. Ivanova, and W.M. Bonner DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139 J. Biol. Chem. 273 1998 5858 5868 (Pubitemid 28124064)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.10 , pp. 5858-5868
    • Rogakou, E.P.1    Pilch, D.R.2    Orr, A.H.3    Ivanova, V.S.4    Bonner, W.M.5
  • 39
    • 0035898405 scopus 로고    scopus 로고
    • Characterization of homologous recombination induced by replication inhibition in mammalian cells
    • DOI 10.1093/emboj/20.14.3861
    • Y. Saintigny, F. Delacôte, G. Vars, F. Petitot, S. Lambert, D. Averbeck, and B.S. Lopez Characterization of homologous recombination induced by replication inhibition in mammalian cells EMBO J. 20 2001 3861 3870 (Pubitemid 32694383)
    • (2001) EMBO Journal , vol.20 , Issue.14 , pp. 3861-3870
    • Saintigny, Y.1    Delacote, F.2    Vares, G.3    Petitot, F.4    Lambert, S.5    Averbeck, D.6    Lopez, B.S.7
  • 40
    • 0026801917 scopus 로고
    • Quantitation of deoxyribonucleoside 5′-triphosphates by a sequential boronate and anion-exchange high-pressure liquid chromatographic procedure
    • D.S. Shewach Quantitation of deoxyribonucleoside 5′-triphosphates by a sequential boronate and anion-exchange high-pressure liquid chromatographic procedure Anal. Biochem. 206 1992 178 182
    • (1992) Anal. Biochem. , vol.206 , pp. 178-182
    • Shewach, D.S.1
  • 41
    • 0034594978 scopus 로고    scopus 로고
    • A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage
    • DOI 10.1038/35003506
    • H. Tanaka, H. Arakawa, T. Yamaguchi, K. Shiraishi, S. Fukuda, K. Matsui, Y. Takei, and Y. Nakamura A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage Nature 404 2000 42 49 (Pubitemid 30143125)
    • (2000) Nature , vol.404 , Issue.6773 , pp. 42-49
    • Tanaka, H.1    Arakawa, H.2    Yamaguchi, T.3    Shiraishi, K.4    Fukuda, S.5    Matsui, K.6    Takei, Y.7    Nakamura, Y.8
  • 42
    • 0031577693 scopus 로고    scopus 로고
    • The human papillomavirus-16 E6 oncoprotein decreases the vigilance of mitotic checkpoints
    • D.A. Thompson, G. Belinsky, T.H. Chang, D.L. Jones, R. Schlegel, and K. Münger The human papillomavirus-16 E6 oncoprotein decreases the vigilance of mitotic checkpoints Oncogene 15 1997 3025 3035 (Pubitemid 28043482)
    • (1997) Oncogene , vol.15 , Issue.25 , pp. 3025-3035
    • Thompson, D.A.1    Belinsky, G.2    Chang, T.H.-T.3    Jones, D.L.4    Schlegel, R.5    Munger, K.6
  • 45
    • 0023197342 scopus 로고
    • The effect of hydroxyurea on the expression of the common fragile site at 3p14
    • Z.A. Yan, X.Z. Li, and X.T. Zhou The effect of hydroxyurea on the expression of the common fragile site at 3p14 J. Med. Genet. 24 1987 593 596
    • (1987) J. Med. Genet. , vol.24 , pp. 593-596
    • Yan, Z.A.1    Li, X.Z.2    Zhou, X.T.3
  • 47
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • Huang, W., Sherman, B.T., and Lempicki, R.A. (2009). Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat. Protoc. 4, 44-57.
    • (2009) Nat. Protoc. , vol.4 , pp. 44-57
    • Huang, W.1    Sherman, B.T.2    Lempicki, R.A.3


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