DNA ligase III promotes alternative nonhomologous end-joining during chromosomal translocation formation

PLoS Genetics

Volumn 7, Issue 6, 2011, Pages

  Simsek, Deniz ^a,b   Brunet, Erika ^c,d,e   Wong, Sunnie Yan Wai ^f   Katyal, Sachin ^g   Gao, Yankun ^g   McKinnon, Peter J ^g   Lou, Jacqueline ^f   Zhang, Lei ^f   Li, James ^f   Rebar, Edward J ^f   Gregory, Philip D ^f   Holmes, Michael C ^f   Jasin, Maria ^a,b  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b Weill Cornell Graduate School of Biomedical Sciences   (United States)

^c MUSÉUM NATIONAL D'HISTOIRE NATURELLE   (France)

^d CNRS   (France)

^e INSERM   (France)

^f SANGAMO BIOSCIENCES INC   (United States)

^g ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENDONUCLEASE; LIGASE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE I; POLYDEOXYRIBONUCLEOTIDE SYNTHASE III; POLYDEOXYRIBONUCLEOTIDE SYNTHASE IV; UNCLASSIFIED DRUG; DNA BINDING PROTEIN; DNA LIGASE III; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE (ATP);

ANIMAL CELL; ARTICLE; CELL DEATH; CHROMOSOME TRANSLOCATION; CONTROLLED STUDY; DNA REPAIR; DNA STRAND BREAKAGE; EMBRYO; ENZYME ACTIVITY; GENE; GENE DELETION; GENE LOCUS; LIG3 GENE; MOUSE; NONHOMOLOGOUS END JOINING; NONHUMAN; PROTEIN DEPLETION; WILD TYPE; ANIMAL; BIOLOGICAL MODEL; CELL NUCLEUS; GENE TRANSLOCATION; GENETIC TRANSFECTION; GENETICS; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE;

MAMMALIA;

ANIMALS; BASE SEQUENCE; CELL NUCLEUS; DNA LIGASES; DNA REPAIR; DNA-BINDING PROTEINS; MICE; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; TRANSFECTION; TRANSLOCATION, GENETIC;

EID: 79959814259     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002080     Document Type: Article

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