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Volumn 47, Issue , 2013, Pages 1-32

Causes of genome instability

Author keywords

Anaphase bridges; Chromosomal rearrangements; DNA damage response; Fragile sites; Replication stress; Transcription replication collisions

Indexed keywords

ATM PROTEIN; BRCA1 PROTEIN; BRCA2 PROTEIN; CELL CYCLE PROTEIN 6; CHECKPOINT KINASE 1; CHECKPOINT KINASE 2; CLASPIN; CYCLINE; DNA FRAGMENT; DOUBLE STRANDED DNA; HIGH MOBILITY GROUP B1 PROTEIN; HISTONE; HISTONE H2AX; MINICHROMOSOME MAINTENANCE PROTEIN 2; MINICHROMOSOME MAINTENANCE PROTEIN 4; MINICHROMOSOME MAINTENANCE PROTEIN 7; PROTEIN ASF1A; PROTEIN ASF1B; PROTEIN DERIVATIVE; PROTEIN EGL1; PROTEIN FANCM; PROTEIN FEN1; PROTEIN HST3; PROTEIN HST4; RAD18 PROTEIN; RAD52 PROTEIN; REPETITIVE DNA; SINGLE STRANDED DNA; SIRTUIN 2; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 84887595526     PISSN: 00664197     EISSN: 15452948     Source Type: Book Series    
DOI: 10.1146/annurev-genet-111212-133232     Document Type: Review
Times cited : (349)

References (213)
  • 1
    • 30944462801 scopus 로고    scopus 로고
    • Cycles of chromosome instability are associated with a fragile site and are increased by defects in DNA replication and checkpoint controls in yeast
    • Admire A, Shanks L, Danzl N, Wang M, Weier U, et al. 2006. Cycles of chromosome instability are associated with a fragile site and are increased by defects in DNA replication and checkpoint controls in yeast. Genes Dev. 20(2):159-73
    • (2006) Genes Dev. , vol.20 , Issue.2 , pp. 159-173
    • Admire, A.1    Shanks, L.2    Danzl, N.3    Wang, M.4    Weier, U.5
  • 2
    • 84860338675 scopus 로고    scopus 로고
    • R loops: From transcription byproducts to threats to genome stability
    • Aguilera A, García-Muse T. 2012. R loops: from transcription byproducts to threats to genome stability. Mol. Cell 46(2):115-24
    • (2012) Mol. Cell , vol.46 , Issue.2 , pp. 115-124
    • Aguilera, A.1    García-Muse, T.2
  • 3
    • 39449096135 scopus 로고    scopus 로고
    • Genome instability: A mechanistic view of its causes and consequences
    • Aguilera A, Gómez-González B. 2008. Genome instability: a mechanistic view of its causes and consequences. Nat. Rev. Genet. 9(3):204-17
    • (2008) Nat. Rev. Genet. , vol.9 , Issue.3 , pp. 204-217
    • Aguilera, A.1    Gómez-González, B.2
  • 4
    • 0024058351 scopus 로고
    • Genetic control of intrachromosomal recombination in Saccharomyces cere-visiae. I. Isolation and genetic characterization of hyper-recombination mutations
    • Aguilera A, Klein HL. 1988. Genetic control of intrachromosomal recombination in Saccharomyces cere-visiae. I. Isolation and genetic characterization of hyper-recombination mutations. Genetics 119(4):779-90
    • (1988) Genetics , vol.119 , Issue.4 , pp. 779-790
    • Aguilera, A.1    Klein, H.L.2
  • 5
    • 0024694243 scopus 로고
    • Genetic and molecular analysis of recombination events in Saccharomyces cerevisiae occurring in the presence of the hyper-recombination mutation hpr1
    • Aguilera A, Klein HL. 1989. Genetic and molecular analysis of recombination events in Saccharomyces cerevisiae occurring in the presence of the hyper-recombination mutation hpr1. Genetics 122(3):503-17
    • (1989) Genetics , vol.122 , Issue.3 , pp. 503-517
    • Aguilera, A.1    Klein, H.L.2
  • 6
    • 84857430552 scopus 로고    scopus 로고
    • Chromatin replication and epigenome maintenance
    • Alabert C, Groth A. 2012. Chromatin replication and epigenome maintenance. Nat. Rev. Mol. Cell Biol. 13(3):153-67
    • (2012) Nat. Rev. Mol. Cell Biol. , vol.13 , Issue.3 , pp. 153-167
    • Alabert, C.1    Groth, A.2
  • 7
    • 37748999305 scopus 로고    scopus 로고
    • Genome-wide analysis of Rad52 foci reveals diverse mechanisms impacting recombination
    • Alvaro D, Lisby M, Rothstein R. 2007. Genome-wide analysis of Rad52 foci reveals diverse mechanisms impacting recombination. PLoS Genet. 3(12):e228
    • (2007) PLoS Genet. , vol.3 , Issue.12
    • Alvaro, D.1    Lisby, M.2    Rothstein, R.3
  • 8
    • 84869026790 scopus 로고    scopus 로고
    • Senataxin associates with replication forks to protect fork integrity across RNA-polymerase-II-transcribed genes
    • Alzu A, Bermejo R, Begnis M, Lucca C, Piccini D, et al. 2012. Senataxin associates with replication forks to protect fork integrity across RNA-polymerase-II-transcribed genes. Cell 151(4):835-46
    • (2012) Cell , vol.151 , Issue.4 , pp. 835-846
    • Alzu, A.1    Bermejo, R.2    Begnis, M.3    Lucca, C.4    Piccini, D.5
  • 9
    • 0042743766 scopus 로고    scopus 로고
    • Dynamics of DNA replication in mammalian somatic cells: Nucleotide pool modulates origin choice and interorigin spacing
    • Anglana M, Apiou F, Bensimon A, Debatisse M. 2003. Dynamics of DNA replication in mammalian somatic cells: nucleotide pool modulates origin choice and interorigin spacing. Cell 114(3):385-94
    • (2003) Cell , vol.114 , Issue.3 , pp. 385-394
    • Anglana, M.1    Apiou, F.2    Bensimon, A.3    Debatisse, M.4
  • 10
    • 3242712112 scopus 로고    scopus 로고
    • BRCA1 is required for common-fragile-site stability via its G2/M checkpoint function
    • Arlt MF, Xu B, Durkin SG, Casper AM, Kastan MB, Glover TW. 2004. BRCA1 is required for common-fragile-site stability via its G2/M checkpoint function. Mol. Cell. Biol. 24(15):6701-9
    • (2004) Mol. Cell. Biol. , vol.24 , Issue.15 , pp. 6701-6709
    • Arlt, M.F.1    Xu, B.2    Durkin, S.G.3    Casper, A.M.4    Kastan, M.B.5    Glover, T.W.6
  • 11
    • 33751237066 scopus 로고    scopus 로고
    • The S cerevisiae Rrm3p DNA helicase moves with the replication fork and affects replication of all yeast chromosomes
    • Azvolinsky A, Dunaway S, Torres JZ, Bessler JB, Zakian VA. 2006. The S cerevisiae Rrm3p DNA helicase moves with the replication fork and affects replication of all yeast chromosomes. Genes Dev. 20(22):3104-16
    • (2006) Genes Dev. , vol.20 , Issue.22 , pp. 3104-3116
    • Azvolinsky, A.1    Dunaway, S.2    Torres, J.Z.3    Bessler, J.B.4    Zakian, V.A.5
  • 12
    • 67449113551 scopus 로고    scopus 로고
    • Highly transcribed RNA polymerase II genes are impediments to replication fork progression in Saccharomyces cerevisiae
    • Azvolinsky A, Giresi PG, Lieb JD, Zakian VA. 2009. Highly transcribed RNA polymerase II genes are impediments to replication fork progression in Saccharomyces cerevisiae. Mol. Cell 34(6):722-34
    • (2009) Mol. Cell , vol.34 , Issue.6 , pp. 722-734
    • Azvolinsky, A.1    Giresi, P.G.2    Lieb, J.D.3    Zakian, V.A.4
  • 13
    • 84873310832 scopus 로고    scopus 로고
    • Identification of early replicating fragile sites that contribute to genome instability
    • Barlow JH, Faryabi RB, Callen E, Wong N, Malhowski A, et al. 2013. Identification of early replicating fragile sites that contribute to genome instability. Cell 152(3):620-32
    • (2013) Cell , vol.152 , Issue.3 , pp. 620-632
    • Barlow, J.H.1    Faryabi, R.B.2    Callen, E.3    Wong, N.4    Malhowski, A.5
  • 15
    • 17244367849 scopus 로고    scopus 로고
    • DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
    • Bartkova J, Horejsí Z, Koed K, Krämer A, Tort F, et al. 2005. DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis. Nature 434(7035):864-70
    • (2005) Nature , vol.434 , Issue.7035 , pp. 864-870
    • Bartkova, J.1    Horejsí, Z.2    Koed, K.3    Krämer, A.4    Tort, F.5
  • 16
    • 33845235459 scopus 로고    scopus 로고
    • Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints
    • Bartkova J, Rezaei N, Liontos M, Karakaidos P, Kletsas D, et al. 2006. Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints. Nature 444(7119):633-37
    • (2006) Nature , vol.444 , Issue.7119 , pp. 633-637
    • Bartkova, J.1    Rezaei, N.2    Liontos, M.3    Karakaidos, P.4    Kletsas, D.5
  • 17
    • 79551681406 scopus 로고    scopus 로고
    • The RNA exosome targets the AID cytidine deaminase to both strands of transcribed duplex DNA substrates
    • Basu U, Meng F-L, Keim C, Grinstein V, Pefanis E, et al. 2011. The RNA exosome targets the AID cytidine deaminase to both strands of transcribed duplex DNA substrates. Cell 144(3):353-63
    • (2011) Cell , vol.144 , Issue.3 , pp. 353-363
    • Basu, U.1    Meng, F.-L.2    Keim, C.3    Grinstein, V.4    Pefanis, E.5
  • 18
    • 0020806166 scopus 로고
    • Properties of the T4 bacteriophage DNA replication apparatus: The T4 dda DNA helicase is required to pass a bound RNA polymerase molecule
    • Bedinger P, Hochstrasser M, Jongeneel CV, Alberts BM. 1983. Properties of the T4 bacteriophage DNA replication apparatus: The T4 dda DNA helicase is required to pass a bound RNA polymerase molecule. Cell 34(1):115-23
    • (1983) Cell , vol.34 , Issue.1 , pp. 115-123
    • Bedinger, P.1    Hochstrasser, M.2    Jongeneel, C.V.3    Alberts, B.M.4
  • 20
    • 69449108384 scopus 로고    scopus 로고
    • Genome-organizing factors Top2 and Hmo1 prevent chromosome fragility at sites of S phase transcription
    • Bermejo R, Capra T, Gonzalez-Huici V, Fachinetti D, Cocito A, et al. 2009. Genome-organizing factors Top2 and Hmo1 prevent chromosome fragility at sites of S phase transcription. Cell 138(5):870-84
    • (2009) Cell , vol.138 , Issue.5 , pp. 870-884
    • Bermejo, R.1    Capra, T.2    Gonzalez-Huici, V.3    Fachinetti, D.4    Cocito, A.5
  • 21
    • 79960802984 scopus 로고    scopus 로고
    • The replication checkpoint protects fork stability by releasing transcribed genes from nuclear pores
    • Bermejo R, Capra T, Jossen R, Colosio A, Frattini C, et al. 2011. The replication checkpoint protects fork stability by releasing transcribed genes from nuclear pores. Cell 146(2):233-46
    • (2011) Cell , vol.146 , Issue.2 , pp. 233-246
    • Bermejo, R.1    Capra, T.2    Jossen, R.3    Colosio, A.4    Frattini, C.5
  • 22
    • 79961170861 scopus 로고    scopus 로고
    • How dormant origins promote complete genome replication
    • Blow JJ, Ge XQ, Jackson DA. 2011. How dormant origins promote complete genome replication. Trends Biochem. Sci. 36(8):405-14
    • (2011) Trends Biochem. Sci. , vol.36 , Issue.8 , pp. 405-414
    • Blow, J.J.1    Ge, X.Q.2    Jackson, D.A.3
  • 23
    • 84861992434 scopus 로고    scopus 로고
    • Activation of the replicative DNA helicase: Breaking up is hard to do
    • Boos D, Frigola J, Diffley JFX. 2012. Activation of the replicative DNA helicase: Breaking up is hard to do. Curr. Opin. Cell Biol. 24(3):423-30
    • (2012) Curr. Opin. Cell Biol. , vol.24 , Issue.3 , pp. 423-430
    • Boos, D.1    Frigola, J.2    Diffley, J.F.X.3
  • 24
    • 75649142564 scopus 로고    scopus 로고
    • The helicases Din G, Rep and UvrD cooperate to promote replication across transcription units in vivo
    • Boubakri H, de Septenville AL, Viguera E, Michel B. 2010. The helicases Din G, Rep and UvrD cooperate to promote replication across transcription units in vivo. EMBO J. 29(1):145-57
    • (2010) EMBO J. , vol.29 , Issue.1 , pp. 145-157
    • Boubakri, H.1    De Septenville, A.L.2    Viguera, E.3    Michel, B.4
  • 25
    • 33750437743 scopus 로고    scopus 로고
    • Ubc9-and Mms21-mediated sumoylation counteracts recombinogenic events at damaged replication forks
    • Branzei D, Sollier J, Liberi G, Zhao X, Maeda D, et al. 2006. Ubc9-and Mms21-mediated sumoylation counteracts recombinogenic events at damaged replication forks. Cell 127(3):509-22
    • (2006) Cell , vol.127 , Issue.3 , pp. 509-522
    • Branzei, D.1    Sollier, J.2    Liberi, G.3    Zhao, X.4    Maeda, D.5
  • 26
    • 0026645804 scopus 로고
    • The arrest of replication forks in the rDNA of yeast occurs independently of transcription
    • Brewer BJ, Lockshon D, Fangman WL. 1992. The arrest of replication forks in the rDNA of yeast occurs independently of transcription. Cell 71(2):267-76
    • (1992) Cell , vol.71 , Issue.2 , pp. 267-276
    • Brewer, B.J.1    Lockshon, D.2    Fangman, W.L.3
  • 27
    • 23944507608 scopus 로고    scopus 로고
    • Molecular anatomy and regulation of a stable replisome at a paused eukaryotic DNA replication fork
    • Calzada A, Hodgson B, Kanemaki M, Bueno A, Labib K. 2005. Molecular anatomy and regulation of a stable replisome at a paused eukaryotic DNA replication fork. Genes Dev. 19(16):1905-19
    • (2005) Genes Dev. , vol.19 , Issue.16 , pp. 1905-1919
    • Calzada, A.1    Hodgson, B.2    Kanemaki, M.3    Bueno, A.4    Labib, K.5
  • 28
    • 0037074013 scopus 로고    scopus 로고
    • ATR regulates fragile site stability
    • Casper AM, Nghiem P, Arlt MF, Glover TW. 2002. ATR regulates fragile site stability. Cell 111(6):779-89
    • (2002) Cell , vol.111 , Issue.6 , pp. 779-789
    • Casper, A.M.1    Nghiem, P.2    Arlt, M.F.3    Glover, T.W.4
  • 29
    • 84867021526 scopus 로고    scopus 로고
    • R-loops cause replication impairment and genome instability during meiosis
    • Castellano-Pozo M, García-Muse T, Aguilera A. 2012. R-loops cause replication impairment and genome instability during meiosis. EMBO Rep. 13(10):923-29
    • (2012) EMBO Rep. , vol.13 , Issue.10 , pp. 923-929
    • Castellano-Pozo, M.1    García-Muse, T.2    Aguilera, A.3
  • 30
    • 0037178723 scopus 로고    scopus 로고
    • ATR homolog Mec1 promotes fork progression, thus averting breaks in replication slow zones
    • Cha RS, Kleckner N. 2002. ATR homolog Mec1 promotes fork progression, thus averting breaks in replication slow zones. Science 297(5581):602-6
    • (2002) Science , vol.297 , Issue.5581 , pp. 602-606
    • Cha, R.S.1    Kleckner, N.2
  • 31
    • 67349227137 scopus 로고    scopus 로고
    • Replication stress induces sister-chromatid bridging at fragile site loci in mitosis
    • Chan KL, Palmai-Pallag T, Ying S, Hickson ID. 2009. Replication stress induces sister-chromatid bridging at fragile site loci in mitosis. Nat. Cell Biol. 11(6):753-60
    • (2009) Nat. Cell Biol. , vol.11 , Issue.6 , pp. 753-760
    • Chan, K.L.1    Palmai-Pallag, T.2    Ying, S.3    Hickson, I.D.4
  • 32
    • 3142765336 scopus 로고    scopus 로고
    • Class-switch recombination: Interplay of transcription, DNA deamination and DNA repair
    • Chaudhuri J, Alt FW. 2004. Class-switch recombination: interplay of transcription, DNA deamination and DNA repair. Nat. Rev. Immunol. 4(7):541-52
    • (2004) Nat. Rev. Immunol. , vol.4 , Issue.7 , pp. 541-552
    • Chaudhuri, J.1    Alt, F.W.2
  • 33
    • 0032860479 scopus 로고    scopus 로고
    • Gross chromosomal rearrangements in Saccharomyces cerevisiae replication and recombination defective mutants
    • Chen C, Kolodner RD. 1999. Gross chromosomal rearrangements in Saccharomyces cerevisiae replication and recombination defective mutants. Nat. Genet. 23(1):81-85
    • (1999) Nat. Genet. , vol.23 , Issue.1 , pp. 81-85
    • Chen, C.1    Kolodner, R.D.2
  • 34
    • 0032109778 scopus 로고    scopus 로고
    • Chromosomal rearrangements occur in S cerevisiae rfa1 mutator mutants due to mutagenic lesions processed by double-strand-break repair
    • Chen C, Umezu K, Kolodner RD. 1998. Chromosomal rearrangements occur in S cerevisiae rfa1 mutator mutants due to mutagenic lesions processed by double-strand-break repair. Mol. Cell 2(1):9-22
    • (1998) Mol. Cell , vol.2 , Issue.1 , pp. 9-22
    • Chen, C.1    Umezu, K.2    Kolodner, R.D.3
  • 35
    • 0024277974 scopus 로고
    • Mitotic recombination in the rDNA of S cerevisiae is suppressed by the combined action of DNA topoisomerases i and II
    • Christman MF, Dietrich FS, Fink GR. 1988. Mitotic recombination in the rDNA of S cerevisiae is suppressed by the combined action of DNA topoisomerases I and II. Cell 55(3):413-25
    • (1988) Cell , vol.55 , Issue.3 , pp. 413-425
    • Christman, M.F.1    Dietrich, F.S.2    Fink, G.R.3
  • 36
    • 78649336706 scopus 로고    scopus 로고
    • The DNA damage response: Making it safe to play with knives
    • Ciccia A, Elledge SJ. 2010. The DNA damage response: making it safe to play with knives. Mol. Cell 40(2):179-204
    • (2010) Mol. Cell , vol.40 , Issue.2 , pp. 179-204
    • Ciccia, A.1    Elledge, S.J.2
  • 37
    • 47749141560 scopus 로고    scopus 로고
    • ATR: An essential regulator of genome integrity
    • Cimprich KA, Cortez D. 2008. ATR: an essential regulator of genome integrity. Nat. Rev. Mol. Cell Biol. 9(8):616-27
    • (2008) Nat. Rev. Mol. Cell Biol. , vol.9 , Issue.8 , pp. 616-627
    • Cimprich, K.A.1    Cortez, D.2
  • 38
    • 0042466524 scopus 로고    scopus 로고
    • DNA polymerase stabilization at stalled replication forks requires Mec1 and the RecQ helicase Sgs1
    • Cobb JA, Bjergbaek L, Shimada K, Frei C, Gasser SM. 2003. DNA polymerase stabilization at stalled replication forks requires Mec1 and the RecQ helicase Sgs1. EMBO J. 22(16):4325-36
    • (2003) EMBO J. , vol.22 , Issue.16 , pp. 4325-4336
    • Cobb, J.A.1    Bjergbaek, L.2    Shimada, K.3    Frei, C.4    Gasser, S.M.5
  • 39
    • 33749511276 scopus 로고    scopus 로고
    • Double-strand breaks arising by replication through a nick are repaired by cohesin-dependent sister-chromatid exchange
    • Cortés-Ledesma F, Aguilera A. 2006. Double-strand breaks arising by replication through a nick are repaired by cohesin-dependent sister-chromatid exchange. EMBO Rep. 7(9):919-26
    • (2006) EMBO Rep. , vol.7 , Issue.9 , pp. 919-926
    • Cortés-Ledesma, F.1    Aguilera, A.2
  • 40
    • 84855477961 scopus 로고    scopus 로고
    • Ataxia telangiectasia mutated (ATM) modulates long interspersed element-1 (L1) retrotransposition in human neural stem cells
    • Coufal NG, Garcia-Perez JL, Peng GE, Marchetto MCN, Muotri AR, et al. 2011. Ataxia telangiectasia mutated (ATM) modulates long interspersed element-1 (L1) retrotransposition in human neural stem cells. Proc. Natl. Acad. Sci. USA 108(51):20382-87
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , Issue.51 , pp. 20382-20387
    • Coufal, N.G.1    Garcia-Perez, J.L.2    Peng, G.E.3    Marchetto, M.C.N.4    Muotri, A.R.5
  • 41
    • 77957363057 scopus 로고    scopus 로고
    • Cohesin is limiting for the suppression of DNA damage-induced recombination between homologous chromosomes
    • Covo S, Westmoreland JW, Gordenin DA, Resnick MA. 2010. Cohesin is limiting for the suppression of DNA damage-induced recombination between homologous chromosomes. PLoS Genet. 6(7):e1001006
    • (2010) PLoS Genet. , vol.6 , Issue.7
    • Covo, S.1    Westmoreland, J.W.2    Gordenin, D.A.3    Resnick, M.A.4
  • 42
    • 84856424908 scopus 로고    scopus 로고
    • DNA breaks and chromosome pulverization from errors in mitosis
    • Crasta K, Ganem NJ, Dagher R, Lantermann AB, Ivanova EV, et al. 2012. DNA breaks and chromosome pulverization from errors in mitosis. Nature 482(7383):53-58
    • (2012) Nature , vol.482 , Issue.7383 , pp. 53-58
    • Crasta, K.1    Ganem, N.J.2    Dagher, R.3    Lantermann, A.B.4    Ivanova, E.V.5
  • 43
    • 0035882059 scopus 로고    scopus 로고
    • A DNA replication-arrest site RTS1 regulates imprinting by determining the direction of replication at mat1 in S pombe
    • Dalgaard JZ, Klar AJ. 2001. A DNA replication-arrest site RTS1 regulates imprinting by determining the direction of replication at mat1 in S. pombe. Genes Dev. 15(16):2060-68
    • (2001) Genes Dev. , vol.15 , Issue.16 , pp. 2060-2068
    • Dalgaard, J.Z.1    Klar, A.J.2
  • 44
    • 33750472654 scopus 로고    scopus 로고
    • Deregulated replication licensing causes DNA fragmentation consistent with head-to-tail fork collision
    • Davidson IF, Li A, Blow JJ. 2006. Deregulated replication licensing causes DNA fragmentation consistent with head-to-tail fork collision. Mol. Cell 24(3):433-43
    • (2006) Mol. Cell , vol.24 , Issue.3 , pp. 433-443
    • Davidson, I.F.1    Li, A.2    Blow, J.J.3
  • 45
    • 0035902495 scopus 로고    scopus 로고
    • Links between replication and recombination in Saccharomyces cerevisiae: A hypersensitive requirement for homologous recombination in the absence of Rad27 activity
    • Debrauwère H, Loeillet S, Lin W, Lopes J, Nicolas A. 2001. Links between replication and recombination in Saccharomyces cerevisiae: a hypersensitive requirement for homologous recombination in the absence of Rad27 activity. Proc. Natl. Acad. Sci. USA 98(15):8263-69
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , Issue.15 , pp. 8263-8269
    • Debrauwère, H.1    Loeillet, S.2    Lin, W.3    Lopes, J.4    Nicolas, A.5
  • 46
    • 71149093724 scopus 로고    scopus 로고
    • How telomeres solve the end-protection problem
    • de Lange T. 2009. How telomeres solve the end-protection problem. Science 326(5955):948-52
    • (2009) Science , vol.326 , Issue.5955 , pp. 948-952
    • De Lange, T.1
  • 47
    • 34548317418 scopus 로고    scopus 로고
    • Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1
    • Denchi EL, de Lange T. 2007. Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1. Nature 448(7157):1068-71
    • (2007) Nature , vol.448 , Issue.7157 , pp. 1068-1071
    • Denchi, E.L.1    De Lange, T.2
  • 48
    • 84858053395 scopus 로고    scopus 로고
    • Replisome stability at defective DNA replication forks is independent of S phase checkpoint kinases
    • De Piccoli G, Katou Y, Itoh T, Nakato R, Shirahige K, Labib K. 2012. Replisome stability at defective DNA replication forks is independent of S phase checkpoint kinases. Mol. Cell 45(5):696-704
    • (2012) Mol. Cell , vol.45 , Issue.5 , pp. 696-704
    • De Piccoli, G.1    Katou, Y.2    Itoh, T.3    Nakato, R.4    Shirahige, K.5    Labib, K.6
  • 49
    • 84860578766 scopus 로고    scopus 로고
    • Replication fork reversal after replication-transcription collision
    • De Septenville AL, Duigou S, Boubakri H, Michel B. 2012. Replication fork reversal after replication-transcription collision. PLoS Genet. 8(4):e1002622
    • (2012) PLoS Genet. , vol.8 , Issue.4
    • De Septenville, A.L.1    Duigou, S.2    Boubakri, H.3    Michel, B.4
  • 50
    • 0029740114 scopus 로고    scopus 로고
    • DNA replication fork pause sites dependent on transcription
    • Deshpande AM, Newlon CS. 1996. DNA replication fork pause sites dependent on transcription. Science 272(5264):1030-33
    • (1996) Science , vol.272 , Issue.5264 , pp. 1030-1033
    • Deshpande, A.M.1    Newlon, C.S.2
  • 51
    • 57049132043 scopus 로고    scopus 로고
    • 53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility
    • Dimitrova N, Chen YC, Spector DL, de Lange T. 2006. 53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility. Nature 456(7221):524-28
    • (2006) Nature , vol.456 , Issue.7221 , pp. 524-528
    • Dimitrova, N.1    Chen, Y.C.2    Spector, D.L.3    De Lange, T.4
  • 53
    • 34547232986 scopus 로고    scopus 로고
    • Non-transcriptional control of DNA replication by c-Myc
    • Dominguez-Sola D, Ying CY, Grandori C, Ruggiero L, Chen B, et al. 2007. Non-transcriptional control of DNA replication by c-Myc. Nature 448(7152):445-51
    • (2007) Nature , vol.448 , Issue.7152 , pp. 445-451
    • Dominguez-Sola, D.1    Ying, C.Y.2    Grandori, C.3    Ruggiero, L.4    Chen, B.5
  • 54
    • 84871740379 scopus 로고    scopus 로고
    • Coordinated control of replication and transcription by a SAPK protects genomic integrity
    • Duch A, Felipe-Abrio I, Barroso S, Yaakov G, García-Rubio M, et al. 2013. Coordinated control of replication and transcription by a SAPK protects genomic integrity. Nature 493(7430):116-19
    • (2013) Nature , vol.493 , Issue.7430 , pp. 116-119
    • Duch, A.1    Felipe-Abrio, I.2    Barroso, S.3    Yaakov, G.4    García-Rubio, M.5
  • 55
    • 0023957740 scopus 로고
    • Transcription stimulates recombination. I. Specialized transduction of Escherichia coli by lambda trp phages
    • Dul JL, Drexler H. 1988. Transcription stimulates recombination. I. Specialized transduction of Escherichia coli by lambda trp phages. Virology 162(2):466-70
    • (1988) Virology , vol.162 , Issue.2 , pp. 466-470
    • Dul, J.L.1    Drexler, H.2
  • 56
    • 3042785608 scopus 로고    scopus 로고
    • Intracellular transcription of G-rich DNAs induces formation of G-loops, novel structures containing G4 DNA
    • Duquette ML, Handa P, Vincent JA, Taylor AF, Maizels N. 2004. Intracellular transcription of G-rich DNAs induces formation of G-loops, novel structures containing G4 DNA. Genes Dev. 18(13):1618-29
    • (2004) Genes Dev. , vol.18 , Issue.13 , pp. 1618-1629
    • Duquette, M.L.1    Handa, P.2    Vincent, J.A.3    Taylor, A.F.4    Maizels, N.5
  • 58
    • 80052008241 scopus 로고    scopus 로고
    • Linking RNA polymerase backtracking to genome instability in E coli
    • Dutta D, Shatalin K, Epshtein V, Gottesman ME, Nudler E. 2011. Linking RNA polymerase backtracking to genome instability in E coli. Cell 146(4):533-43
    • (2011) Cell , vol.146 , Issue.4 , pp. 533-543
    • Dutta, D.1    Shatalin, K.2    Epshtein, V.3    Gottesman, M.E.4    Nudler, E.5
  • 59
    • 29144522146 scopus 로고    scopus 로고
    • Premature condensation induces breaks at the interface of early and late replicating chromosome bands bearing common fragile sites
    • El Achkar E, Gerbault-Seureau M, Muleris M, Dutrillaux B, Debatisse M. 2005. Premature condensation induces breaks at the interface of early and late replicating chromosome bands bearing common fragile sites. Proc. Natl. Acad. Sci. USA 102(50):18069-74
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , Issue.50 , pp. 18069-18074
    • El Achkar, E.1    Gerbault-Seureau, M.2    Muleris, M.3    Dutrillaux, B.4    Debatisse, M.5
  • 60
    • 77954841539 scopus 로고    scopus 로고
    • Loss of topoisomerase i leads to R-loop-mediated transcriptional blocks during ribosomal RNA synthesis
    • El Hage A, French SL, Beyer AL, Tollervey D. 2010. Loss of topoisomerase I leads to R-loop-mediated transcriptional blocks during ribosomal RNA synthesis. Genes Dev. 24(14):1546-58
    • (2010) Genes Dev. , vol.24 , Issue.14 , pp. 1546-1558
    • El Hage, A.1    French, S.L.2    Beyer, A.L.3    Tollervey, D.4
  • 61
    • 1842377482 scopus 로고    scopus 로고
    • Bacteriophage phi29 DNA replication arrest caused by codirectional collisions with the transcription machinery
    • Elías-Arnanz M, Salas M. 1997. Bacteriophage phi29 DNA replication arrest caused by codirectional collisions with the transcription machinery. EMBO J. 16(18):5775-83
    • (1997) EMBO J. , vol.16 , Issue.18 , pp. 5775-5783
    • Elías-Arnanz, M.1    Salas, M.2
  • 62
    • 77955997707 scopus 로고    scopus 로고
    • Replication termination ateukaryotic chromosomes is mediated by Top2 and occurs at genomic loci containing pausing elements
    • Fachinetti D, Bermejo R, Cocito A, Minardi S, Katou Y, et al. 2010. Replication termination ateukaryotic chromosomes is mediated by Top2 and occurs at genomic loci containing pausing elements. Mol. Cell 39(4):595-605
    • (2010) Mol. Cell , vol.39 , Issue.4 , pp. 595-605
    • Fachinetti, D.1    Bermejo, R.2    Cocito, A.3    Minardi, S.4    Katou, Y.5
  • 63
    • 0026733965 scopus 로고
    • Consequences of replication fork movement through transcription units in vivo
    • French S. 1992. Consequences of replication fork movement through transcription units in vivo. Science 258(5086):1362-65
    • (1992) Science , vol.258 , Issue.5086 , pp. 1362-1365
    • French, S.1
  • 64
    • 28844506236 scopus 로고    scopus 로고
    • Suffering in silence: The tolerance of DNA damage
    • Friedberg EC. 2005. Suffering in silence: the tolerance of DNA damage. Nat. Rev. Mol. Cell Biol. 6(12):943-53
    • (2005) Nat. Rev. Mol. Cell Biol. , vol.6 , Issue.12 , pp. 943-953
    • Friedberg, E.C.1
  • 65
    • 0029053371 scopus 로고
    • Trinucleotide repeats that expand in human disease form hairpin structures in vitro
    • Gacy AM, Goellner G, Juranić N, Macura S, McMurray CT. 1995. Trinucleotide repeats that expand in human disease form hairpin structures in vitro. Cell 81(4):533-40
    • (1995) Cell , vol.81 , Issue.4 , pp. 533-540
    • Gacy, A.M.1    Goellner, G.2    Juranić, N.3    MacUra, S.4    McMurray, C.T.5
  • 66
    • 0141467384 scopus 로고    scopus 로고
    • Recombinogenic effects of DNA-damaging agents are synergistically increased by transcription in Saccharomyces cerevisiae. New insights into transcription-associated recombination
    • García-Rubio M, Huertas P, González-Barrera S, Aguilera A. 2003. Recombinogenic effects of DNA-damaging agents are synergistically increased by transcription in Saccharomyces cerevisiae. New insights into transcription-associated recombination. Genetics 165(2):457-66
    • (2003) Genetics , vol.165 , Issue.2 , pp. 457-466
    • García-Rubio, M.1    Huertas, P.2    González-Barrera, S.3    Aguilera, A.4
  • 67
    • 84863769552 scopus 로고    scopus 로고
    • MMS19 links cytoplasmic iron-sulfur cluster assembly to DNA metabolism
    • Gari K, León Ortiz AM, Borel V, Flynn H, Skehel JM, et al. 2012. MMS19 links cytoplasmic iron-sulfur cluster assembly to DNA metabolism. Science 337(6091):243-45
    • (2012) Science , vol.337 , Issue.6091 , pp. 243-245
    • Gari, K.1    León Ortiz, A.M.2    Borel, V.3    Flynn, H.4    Skehel, J.M.5
  • 68
    • 79961031438 scopus 로고    scopus 로고
    • Genome-wide function of THO/TREX in active genes prevents R-loop-dependent replication obstacles
    • Gómez-González B, García-Rubio M, Bermejo R, Gaillard H, Shirahige K, et al. 2011. Genome-wide function of THO/TREX in active genes prevents R-loop-dependent replication obstacles. EMBO J. 30(15):3106-19
    • (2011) EMBO J. , vol.30 , Issue.15 , pp. 3106-3119
    • Gómez-González, B.1    García-Rubio, M.2    Bermejo, R.3    Gaillard, H.4    Shirahige, K.5
  • 69
    • 17244366865 scopus 로고    scopus 로고
    • Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions
    • Gorgoulis VG, Vassiliou LV, Karakaidos P, Zacharatos P, Kotsinas A, et al. 2005. Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions. Nature 434(7035):907-13
    • (2005) Nature , vol.434 , Issue.7035 , pp. 907-913
    • Gorgoulis, V.G.1    Vassiliou, L.V.2    Karakaidos, P.3    Zacharatos, P.4    Kotsinas, A.5
  • 70
    • 37549026516 scopus 로고    scopus 로고
    • Transcription-associated recombination is dependent on replication in mammalian cells
    • Gottipati P, Cassel TN, Savolainen L, Helleday T. 2008. Transcription-associated recombination is dependent on replication in mammalian cells. Mol. Cell. Biol. 28(1):154-64
    • (2008) Mol. Cell. Biol. , vol.28 , Issue.1 , pp. 154-164
    • Gottipati, P.1    Cassel, T.N.2    Savolainen, L.3    Helleday, T.4
  • 71
    • 0024536650 scopus 로고
    • A new role for a yeast transcriptional silencer gene, SIR2, in regulation of recombination in ribosomal DNA
    • Gottlieb S, Esposito RE. 1989. A new role for a yeast transcriptional silencer gene, SIR2, in regulation of recombination in ribosomal DNA. Cell 56(5):771-76
    • (1989) Cell , vol.56 , Issue.5 , pp. 771-776
    • Gottlieb, S.1    Esposito, R.E.2
  • 72
    • 34548775695 scopus 로고    scopus 로고
    • A persistent RNA ·dNA hybrid formedbytranscription of the Friedreich ataxia triplet repeat in live bacteria, and by T7 RNAP in vitro
    • Grabczyk E, Mancuso M, Sammarco MC. 2007. A persistent RNA ·DNA hybrid formedbytranscription of the Friedreich ataxia triplet repeat in live bacteria, and by T7 RNAP in vitro. Nucleic Acids Res. 35(16):5351-59
    • (2007) Nucleic Acids Res. , vol.35 , Issue.16 , pp. 5351-5359
    • Grabczyk, E.1    Mancuso, M.2    Sammarco, M.C.3
  • 73
    • 77955870154 scopus 로고    scopus 로고
    • Loss of DNA replication control is a potent inducer of gene amplification
    • Green BM, Finn KJ, Li JJ. 2010. Loss of DNA replication control is a potent inducer of gene amplification. Science 329(5994):943-46
    • (2010) Science , vol.329 , Issue.5994 , pp. 943-946
    • Green, B.M.1    Finn, K.J.2    Li, J.J.3
  • 74
    • 0021796842 scopus 로고
    • Altered fidelity of mitotic chromosome transmission in cell cycle mutants of S cerevisiae
    • Hartwell LH, Smith D. 1985. Altered fidelity of mitotic chromosome transmission in cell cycle mutants of S cerevisiae. Genetics 110(3):381-95
    • (1985) Genetics , vol.110 , Issue.3 , pp. 381-395
    • Hartwell, L.H.1    Smith, D.2
  • 75
    • 84868091320 scopus 로고    scopus 로고
    • ATR-sensitive fragile sites occurs independently of spindle tension, anaphase, or cytokinesis
    • ATR-sensitive fragile sites occurs independently of spindle tension, anaphase, or cytokinesis. PLoS Genet. 8(10):e1002978
    • (2012) PLoS Genet. , vol.8 , Issue.10
    • Hashash, N.1    Johnson, A.L.2    Cha, R.S.3
  • 78
    • 31844456472 scopus 로고    scopus 로고
    • Replication fork reactivation downstream of a blocked nascent leading strand
    • Heller RC, Marians KJ. 2006. Replication fork reactivation downstream of a blocked nascent leading strand. Nature 439(7076):557-62
    • (2006) Nature , vol.439 , Issue.7076 , pp. 557-562
    • Heller, R.C.1    Marians, K.J.2
  • 79
    • 84255198334 scopus 로고    scopus 로고
    • Collisions between replication and transcription complexes cause common fragile site instability at the longest human genes
    • Helmrich A, Ballarino M, Tora L. 2011. Collisions between replication and transcription complexes cause common fragile site instability at the longest human genes. Mol. Cell 44(6):966-77
    • (2011) Mol. Cell , vol.44 , Issue.6 , pp. 966-977
    • Helmrich, A.1    Ballarino, M.2    Tora, L.3
  • 80
    • 0032059864 scopus 로고    scopus 로고
    • FRA10B structure reveals common elements in repeat expansion and chromosomal fragile site genesis
    • Hewett DR, Handt O, Hobson L, Mangelsdorf M, Eyre HJ, et al. 1998. FRA10B structure reveals common elements in repeat expansion and chromosomal fragile site genesis. Mol. Cell 1(6):773-81
    • (1998) Mol. Cell , vol.1 , Issue.6 , pp. 773-781
    • Hewett, D.R.1    Handt, O.2    Hobson, L.3    Mangelsdorf, M.4    Eyre, H.J.5
  • 81
    • 78149425175 scopus 로고    scopus 로고
    • Regulation of homologous recombination in eukaryotes
    • Heyer WD, Ehmsen KT, Liu J. 2010. Regulation of homologous recombination in eukaryotes. Annu. Rev. Genet. 44:113-39
    • (2010) Annu. Rev. Genet. , vol.44 , pp. 113-139
    • Heyer, W.D.1    Ehmsen, K.T.2    Liu, J.3
  • 82
    • 0024594367 scopus 로고
    • Tus, the trans-acting gene required for termination of DNA replication in Escherichia coli, encodes a DNA-binding protein
    • Hill TM, Tecklenburg ML, Pelletier AJ, Kuempel PL. 1989. tus, the trans-acting gene required for termination of DNA replication in Escherichia coli, encodes a DNA-binding protein. Proc. Natl. Acad. Sci. USA 86(5):1593-97
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , Issue.5 , pp. 1593-1597
    • Hill, T.M.1    Tecklenburg, M.L.2    Pelletier, A.J.3    Kuempel, P.L.4
  • 83
    • 0024499711 scopus 로고
    • DNA topoisomerase II must act at mitosis to prevent nondisjunc-tion and chromosome breakage
    • Holm C, Stearns T, Botstein D. 1989. DNA topoisomerase II must act at mitosis to prevent nondisjunc-tion and chromosome breakage. Mol. Cell. Biol. 9(1):159-68
    • (1989) Mol. Cell. Biol. , vol.9 , Issue.1 , pp. 159-168
    • Holm, C.1    Stearns, T.2    Botstein, D.3
  • 84
    • 0028954628 scopus 로고
    • Recombinational rescue of the stalled DNA replication fork: A model based on analysis of an Escherichia coli strain with a chromosome region difficult to replicate
    • Horiuchi T, Fujimura Y. 1995. Recombinational rescue of the stalled DNA replication fork: a model based on analysis of an Escherichia coli strain with a chromosome region difficult to replicate. J. Bacteriol. 177(3):783-91
    • (1995) J. Bacteriol. , vol.177 , Issue.3 , pp. 783-791
    • Horiuchi, T.1    Fujimura, Y.2
  • 85
    • 0141819093 scopus 로고    scopus 로고
    • Cotranscriptionally formed DNA:RNA hybrids mediate transcription elongation impairment and transcription-associated recombination
    • Huertas P, Aguilera A. 2003. Cotranscriptionally formed DNA:RNA hybrids mediate transcription elongation impairment and transcription-associated recombination. Mol. Cell 12(3):711-21
    • (2003) Mol. Cell , vol.12 , Issue.3 , pp. 711-721
    • Huertas, P.1    Aguilera, A.2
  • 86
    • 48249084972 scopus 로고    scopus 로고
    • Excess MCM proteins protect human cells from replicative stress by licensing backup origins of replication
    • Ibarra A, Schwob E, Méndez J. 2008. Excess MCM proteins protect human cells from replicative stress by licensing backup origins of replication. Proc. Natl. Acad. Sci. USA 105(26):8956-61
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , Issue.26 , pp. 8956-8961
    • Ibarra, A.1    Schwob, E.2    Méndez, J.3
  • 87
    • 0033895728 scopus 로고    scopus 로고
    • The impact of lagging strand replication mutations on the stability of CAG repeat tracts in yeast
    • Ireland MJ, Reinke SS, Livingston DM. 2000. The impact of lagging strand replication mutations on the stability of CAG repeat tracts in yeast. Genetics 155(4):1657-65
    • (2000) Genetics , vol.155 , Issue.4 , pp. 1657-1665
    • Ireland, M.J.1    Reinke, S.S.2    Livingston, D.M.3
  • 88
    • 80053570245 scopus 로고    scopus 로고
    • Lac operator repeats generate a traceable fragile site in mammalian cells
    • Jacome A, Fernandez-Capetillo O. 2011. Lac operator repeats generate a traceable fragile site in mammalian cells. EMBO Rep. 12(10):1032-38
    • (2011) EMBO Rep. , vol.12 , Issue.10 , pp. 1032-1038
    • Jacome, A.1    Fernandez-Capetillo, O.2
  • 89
    • 80053364894 scopus 로고    scopus 로고
    • Chromosome segregation errors as a cause of DNA damage and structural chromosome aberrations
    • Janssen A, van der Burg M, Szuhai K, Kops GJ, Medema RH. 2011. Chromosome segregation errors as a cause of DNA damage and structural chromosome aberrations. Science 333(6051):1895-98
    • (2011) Science , vol.333 , Issue.6051 , pp. 1895-1898
    • Janssen, A.1    Van Der Burg, M.2    Szuhai, K.3    Kops, G.J.4    Medema, R.H.5
  • 90
    • 84857064783 scopus 로고    scopus 로고
    • Dysregulation of DNA polymerase κrecruitment to replication forks results in genomic instability
    • Jones MJ, Colnaghi L, Huang TT. 2012. Dysregulation of DNA polymerase κrecruitment to replication forks results in genomic instability. EMBO J. 31(4):908-18
    • (2012) EMBO J. , vol.31 , Issue.4 , pp. 908-918
    • Jones, M.J.1    Colnaghi, L.2    Huang, T.T.3
  • 91
    • 84881480253 scopus 로고    scopus 로고
    • Increased replication initiation and conflicts with transcription underlie cyclin E-induced replication stress
    • Jones RM, Mortusewicz O, Afzal I, Lorvellec M, García P, et al. 2012. Increased replication initiation and conflicts with transcription underlie cyclin E-induced replication stress. Oncogene 32:3744-53
    • (2012) Oncogene , vol.32 , pp. 3744-3753
    • Jones, R.M.1    Mortusewicz, O.2    Afzal, I.3    Lorvellec, M.4    García, P.5
  • 92
    • 0029035379 scopus 로고
    • Expansion and deletion of CTG repeats from human disease genes are determined by the direction of replication in E coli
    • Kang S, Jaworski A, Ohshima K, Wells RD. 1995. Expansion and deletion of CTG repeats from human disease genes are determined by the direction of replication in E coli. Nat. Genet. 10(2):213-18
    • (1995) Nat. Genet. , vol.10 , Issue.2 , pp. 213-218
    • Kang, S.1    Jaworski, A.2    Ohshima, K.3    Wells, R.D.4
  • 93
    • 79951970806 scopus 로고    scopus 로고
    • Stalled fork rescue via dormant replication origins in unchallenged S phase promotes proper chromosome segregation and tumor suppression
    • Kawabata T, Luebben SW, Yamaguchi S, Ilves I, Matise I, et al. 2011. Stalled fork rescue via dormant replication origins in unchallenged S phase promotes proper chromosome segregation and tumor suppression. Mol. Cell 41(5):543-53
    • (2011) Mol. Cell , vol.41 , Issue.5 , pp. 543-553
    • Kawabata, T.1    Luebben, S.W.2    Yamaguchi, S.3    Ilves, I.4    Matise, I.5
  • 94
    • 0021750302 scopus 로고
    • Cis-acting, recombination-stimulating activity in a fragment of the ribosomal DNA of S cerevisiae
    • Keil RL, Roeder GS. 1984. Cis-acting, recombination-stimulating activity in a fragment of the ribosomal DNA of S cerevisiae. Cell 39:377-86
    • (1984) Cell , vol.39 , pp. 377-386
    • Keil, R.L.1    Roeder, G.S.2
  • 95
    • 55549095970 scopus 로고    scopus 로고
    • Chromosome fragility at GAA tracts in yeast depends on repeat orientation and requires mismatch repair
    • Kim H-M, Narayanan V, Mieczkowski PA, Petes TD, Krasilnikova MM, et al. 2008. Chromosome fragility at GAA tracts in yeast depends on repeat orientation and requires mismatch repair. EMBO J. 27(21):2896-906
    • (2008) EMBO J. , vol.27 , Issue.21 , pp. 2896-2906
    • Kim, H.-M.1    Narayanan, V.2    Mieczkowski, P.A.3    Petes, T.D.4    Krasilnikova, M.M.5
  • 96
    • 84863105790 scopus 로고    scopus 로고
    • Constitutional chromothripsis rearrangements involve clustered double-stranded DNA breaks and non-homologous repair mechanisms
    • Kloosterman WP, Tavakoli-Yaraki M, van Roosmalen MJ, van Binsbergen E, Renkens I, et al. 2012. Constitutional chromothripsis rearrangements involve clustered double-stranded DNA breaks and non-homologous repair mechanisms. Cell Rep. 1(6):648-55
    • (2012) Cell Rep. , vol.1 , Issue.6 , pp. 648-655
    • Kloosterman, W.P.1    Tavakoli-Yaraki, M.2    Van Roosmalen, M.J.3    Van Binsbergen, E.4    Renkens, I.5
  • 97
    • 0344629438 scopus 로고    scopus 로고
    • The replication fork barrier site forms a unique structure with Fob1p and inhibits the replication fork
    • Kobayashi T. 2003. The replication fork barrier site forms a unique structure with Fob1p and inhibits the replication fork. Mol. Cell. Biol. 23(24):9178-88
    • (2003) Mol. Cell. Biol. , vol.23 , Issue.24 , pp. 9178-9188
    • Kobayashi, T.1
  • 98
    • 24644499002 scopus 로고    scopus 로고
    • Recombination regulation by transcription-induced cohesin dissociation in rDNA repeats
    • Kobayashi T, Ganley ARD. 2005. Recombination regulation by transcription-induced cohesin dissociation in rDNA repeats. Science 309(5740):1581-84
    • (2005) Science , vol.309 , Issue.5740 , pp. 1581-1584
    • Kobayashi, T.1    Ganley, A.R.D.2
  • 100
    • 3242658268 scopus 로고    scopus 로고
    • Expanded CAG repeats activate the DNA damage checkpoint pathway
    • Lahiri M, Gustafson TL, Majors ER, Freudenreich CH. 2004. Expanded CAG repeats activate the DNA damage checkpoint pathway. Mol. Cell 15(2):287-93
    • (2004) Mol. Cell , vol.15 , Issue.2 , pp. 287-293
    • Lahiri, M.1    Gustafson, T.L.2    Majors, E.R.3    Freudenreich, C.H.4
  • 101
    • 77955479780 scopus 로고    scopus 로고
    • Homologous recombination restarts blocked replication forks at the expense of genome rearrangements by template exchange
    • Lambert S, Mizuno K, Blaisonneau J, Martineau S, Chanet R, et al. 2010. Homologous recombination restarts blocked replication forks at the expense of genome rearrangements by template exchange. Mol. Cell 39(3):346-59
    • (2010) Mol. Cell , vol.39 , Issue.3 , pp. 346-359
    • Lambert, S.1    Mizuno, K.2    Blaisonneau, J.3    Martineau, S.4    Chanet, R.5
  • 102
    • 20444424939 scopus 로고    scopus 로고
    • Gross chromosomal rearrangements and elevated recombination at an inducible site-specific replication fork barrier
    • Lambert S, Watson A, Sheedy DM, Martin B, Carr AM. 2005. Gross chromosomal rearrangements and elevated recombination at an inducible site-specific replication fork barrier. Cell 121(5):689-702
    • (2005) Cell , vol.121 , Issue.5 , pp. 689-702
    • Lambert, S.1    Watson, A.2    Sheedy, D.M.3    Martin, B.4    Carr, A.M.5
  • 103
    • 79960037006 scopus 로고    scopus 로고
    • Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice
    • Langevin F, Crossan GP, Rosado IV, Arends MJ, Patel KJ. 2011. Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice. Nature 475(7354):53-58
    • (2011) Nature , vol.475 , Issue.7354 , pp. 53-58
    • Langevin, F.1    Crossan, G.P.2    Rosado, I.V.3    Arends, M.J.4    Patel, K.J.5
  • 104
    • 0031924605 scopus 로고    scopus 로고
    • Replication of a common fragile site, FRA3B, occurs late in S phase and is delayed further upon induction: Implications for the mechanism of fragile site induction
    • Le Beau MM, Rassool FV, Neilly ME, Espinosa R, Glover TW, et al. 1998. Replication of a common fragile site, FRA3B, occurs late in S phase and is delayed further upon induction: implications for the mechanism of fragile site induction. Hum. Mol. Genet. 7(4):755-61
    • (1998) Hum. Mol. Genet. , vol.7 , Issue.4 , pp. 755-761
    • Le Beau, M.M.1    Rassool, F.V.2    Neilly, M.E.3    Espinosa, R.4    Glover, T.W.5
  • 105
    • 34249941966 scopus 로고    scopus 로고
    • Translesion synthesis: Y-family polymerases and the polymerase switch
    • Lehmann AR, Niimi A, Ogi T, Brown S, Sabbioneda S, et al. 2007. Translesion synthesis: Y-family polymerases and the polymerase switch. DNA Repair (Amst.) 6(7):891-99
    • (2007) DNA Repair (Amst.) , vol.6 , Issue.7 , pp. 891-899
    • Lehmann, A.R.1    Niimi, A.2    Ogi, T.3    Brown, S.4    Sabbioneda, S.5
  • 106
    • 14844286404 scopus 로고    scopus 로고
    • Chromosomal translocations in yeast induced by low levels of DNA polymerase a model for chromosome fragile sites
    • Lemoine FJ, Degtyareva NP, Lobachev K, Petes TD. 2005. Chromosomal translocations in yeast induced by low levels of DNA polymerase a model for chromosome fragile sites. Cell 120(5):587-98
    • (2005) Cell , vol.120 , Issue.5 , pp. 587-598
    • Lemoine, F.J.1    Degtyareva, N.P.2    Lobachev, K.3    Petes, T.D.4
  • 107
    • 0036278984 scopus 로고    scopus 로고
    • The yeast CDK inhibitor Sic1 prevents genomic instability by promoting replication origin licensing in late G(1)
    • Lengronne A, Schwob E. 2002. The yeast CDK inhibitor Sic1 prevents genomic instability by promoting replication origin licensing in late G(1). Mol. Cell 9(5):1067-78
    • (2002) Mol. Cell , vol.9 , Issue.5 , pp. 1067-1078
    • Lengronne, A.1    Schwob, E.2
  • 109
    • 79551661935 scopus 로고    scopus 로고
    • Cell-type-specific replication initiation programs set fragility of the FRA3B fragile site
    • Letessier A, Millot GA, Koundrioukoff S, Lachages A-M, Vogt N, et al. 2011. Cell-type-specific replication initiation programs set fragility of the FRA3B fragile site. Nature 470(7332):120-23
    • (2011) Nature , vol.470 , Issue.7332 , pp. 120-123
    • Letessier, A.1    Millot, G.A.2    Koundrioukoff, S.3    Lachages, A.-M.4    Vogt, N.5
  • 110
    • 79956140211 scopus 로고    scopus 로고
    • The SET2-RPB1 interaction domain of human RECQ5 is important for transcription-associated genome stability
    • Li M, Xu X, Liu Y. 2011. The SET2-RPB1 interaction domain of human RECQ5 is important for transcription-associated genome stability. Mol. Cell. Biol. 31(10):2090-99
    • (2011) Mol. Cell. Biol. , vol.31 , Issue.10 , pp. 2090-2099
    • Li, M.1    Xu, X.2    Liu, Y.3
  • 111
    • 23744455164 scopus 로고    scopus 로고
    • Inactivation of the SR protein splicing factor ASF/SF2 results in genomic instability
    • Li X, Manley JL. 2005. Inactivation of the SR protein splicing factor ASF/SF2 results in genomic instability. Cell 122(3):365-78
    • (2005) Cell , vol.122 , Issue.3 , pp. 365-378
    • Li, X.1    Manley, J.L.2
  • 112
    • 19944432787 scopus 로고    scopus 로고
    • Rad51-dependent DNA structures accumulate at damaged replication forks in sgs1 mutants defective in the yeast ortholog of BLM RecQ helicase
    • Liberi G, Maffioletti G, Lucca C, Chiolo I, Baryshnikova A, et al. 2005. Rad51-dependent DNA structures accumulate at damaged replication forks in sgs1 mutants defective in the yeast ortholog of BLM RecQ helicase. Genes Dev. 19(3):339-50
    • (2005) Genes Dev. , vol.19 , Issue.3 , pp. 339-350
    • Liberi, G.1    Maffioletti, G.2    Lucca, C.3    Chiolo, I.4    Baryshnikova, A.5
  • 114
    • 79953758066 scopus 로고    scopus 로고
    • Replicative age induces mitotic recombination in the ribosomal RNA gene cluster of Saccharomyces cerevisiae
    • Lindstrom DL, Leverich CK, Henderson KA, Gottschling DE. 2011. Replicative age induces mitotic recombination in the ribosomal RNA gene cluster of Saccharomyces cerevisiae. PLoS Genet. 7(3):e1002015
    • (2011) PLoS Genet. , vol.7 , Issue.3
    • Lindstrom, D.L.1    Leverich, C.K.2    Henderson, K.A.3    Gottschling, D.E.4
  • 115
    • 0028908039 scopus 로고
    • Head-on collision between a DNA replication apparatus and RNA polymerase transcription complex
    • Liu B, Alberts BM. 1995. Head-on collision between a DNA replication apparatus and RNA polymerase transcription complex. Science 267(5201):1131-37
    • (1995) Science , vol.267 , Issue.5201 , pp. 1131-1137
    • Liu, B.1    Alberts, B.M.2
  • 116
    • 74549184412 scopus 로고    scopus 로고
    • The polarisome is required for segregation and retrograde transport of protein aggregates
    • Liu B, Larsson L, Caballero A, Hao X, Oling D, et al. 2010. The polarisome is required for segregation and retrograde transport of protein aggregates. Cell 140(2):257-67
    • (2010) Cell , vol.140 , Issue.2 , pp. 257-267
    • Liu, B.1    Larsson, L.2    Caballero, A.3    Hao, X.4    Oling, D.5
  • 117
    • 80052916562 scopus 로고    scopus 로고
    • Chromosome catastrophes involve replication mechanisms generating complex genomic rearrangements
    • Liu P, Erez A, Nagamani SCS, Dhar SU, Kołodziejska KE, et al. 2011. Chromosome catastrophes involve replication mechanisms generating complex genomic rearrangements. Cell 146(6):889-903
    • (2011) Cell , vol.146 , Issue.6 , pp. 889-903
    • Liu, P.1    Erez, A.2    Nagamani, S.C.S.3    Dhar, S.U.4    Kołodziejska, K.E.5
  • 119
    • 0037169325 scopus 로고    scopus 로고
    • The Mre11 complex is required for repair of hairpin-capped double-strand breaks and prevention of chromosome rearrangements
    • Lobachev KS, Gordenin DA, Resnick MA. 2002. The Mre11 complex is required for repair of hairpin-capped double-strand breaks and prevention of chromosome rearrangements. Cell 108(2):183-93
    • (2002) Cell , vol.108 , Issue.2 , pp. 183-193
    • Lobachev, K.S.1    Gordenin, D.A.2    Resnick, M.A.3
  • 120
    • 61349135721 scopus 로고    scopus 로고
    • FANCJ is a structure-specific DNA helicase associated with the maintenance of genomic G/C tracts
    • London TBC, Barber LJ, Mosedale G, Kelly GP, Balasubramanian S, et al. 2008. FANCJ is a structure-specific DNA helicase associated with the maintenance of genomic G/C tracts. J. Biol. Chem. 283(52):36132-39
    • (2008) J. Biol. Chem. , vol.283 , Issue.52 , pp. 36132-36139
    • London, T.B.C.1    Barber, L.J.2    Mosedale, G.3    Kelly, G.P.4    Balasubramanian, S.5
  • 121
    • 80053611613 scopus 로고    scopus 로고
    • G-quadruplex-induced instability during leading-strand replication
    • Lopes J, le Piazza AE, Bermejo R, Kriegsman B, Colosio A, et al. 2011. G-quadruplex-induced instability during leading-strand replication. EMBO J. 30(19):4033-46
    • (2011) EMBO J. , vol.30 , Issue.19 , pp. 4033-4046
    • Lopes, J.1    Le Piazza, A.E.2    Bermejo, R.3    Kriegsman, B.4    Colosio, A.5
  • 122
    • 27644489367 scopus 로고    scopus 로고
    • Immunoglobulin gene diversification
    • Maizels N. 2005. Immunoglobulin gene diversification. Annu. Rev. Genet. 39:23-46
    • (2005) Annu. Rev. Genet. , vol.39 , pp. 23-46
    • Maizels, N.1
  • 123
    • 0017058932 scopus 로고
    • Hyper-recombination in dam mutants of Escherichia coli K-12
    • Marinus MG, Konrad EB. 1976. Hyper-recombination in dam mutants of Escherichia coli K-12. Mol. Gen. Genet. 149(3):273-77
    • (1976) Mol. Gen. Genet. , vol.149 , Issue.3 , pp. 273-277
    • Marinus, M.G.1    Konrad, E.B.2
  • 124
    • 69749092744 scopus 로고    scopus 로고
    • Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice
    • Martínez P, Thanasoula M, Muñoz P, Liao C, Tejera A, et al. 2009. Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice. Genes Dev. 23(17):2060-75
    • (2009) Genes Dev. , vol.23 , Issue.17 , pp. 2060-2075
    • Martínez, P.1    Thanasoula, M.2    Muñoz, P.3    Liao, C.4    Tejera, A.5
  • 126
    • 22444448143 scopus 로고    scopus 로고
    • A role for cell-cycle-regulated histone H3 lysine 56 acetylation in the DNA damage response
    • Masumoto H, Hawke D, Kobayashi R, Verreault A. 2005. A role for cell-cycle-regulated histone H3 lysine 56 acetylation in the DNA damage response. Nature 436(7048):294-98
    • (2005) Nature , vol.436 , Issue.7048 , pp. 294-298
    • Masumoto, H.1    Hawke, D.2    Kobayashi, R.3    Verreault, A.4
  • 127
    • 0033578040 scopus 로고    scopus 로고
    • The XPV (xeroderma pigmen-tosum variant) gene encodes human DNA polymerase η
    • Masutani C, Kusumoto R, Yamada A, Dohmae N, Yokoi M, et al. 1999. The XPV (xeroderma pigmen-tosum variant) gene encodes human DNA polymerase η. Nature 399(6737):700-4
    • (1999) Nature , vol.399 , Issue.6737 , pp. 700-704
    • Masutani, C.1    Kusumoto, R.2    Yamada, A.3    Dohmae, N.4    Yokoi, M.5
  • 128
    • 80053544629 scopus 로고    scopus 로고
    • Regulatory control of the resolution of DNA recombination intermediates during meiosis and mitosis
    • Matos J, Blanco MG, Maslen S, Skehel JM, West SC. 2011. Regulatory control of the resolution of DNA recombination intermediates during meiosis and mitosis. Cell 147(1):158-72
    • (2011) Cell , vol.147 , Issue.1 , pp. 158-172
    • Matos, J.1    Blanco, M.G.2    Maslen, S.3    Skehel, J.M.4    West, S.C.5
  • 129
    • 0029958255 scopus 로고    scopus 로고
    • Orientation dependence of trinucleotide CAG repeat instability in Saccharomyces cerevisiae
    • Maurer DJ, O'Callaghan BL, Livingston DM. 1996. Orientation dependence of trinucleotide CAG repeat instability in Saccharomyces cerevisiae. Mol. Cell. Biol. 16(12):6617-22
    • (1996) Mol. Cell. Biol. , vol.16 , Issue.12 , pp. 6617-6622
    • Maurer, D.J.1    O'Callaghan, B.L.2    Livingston, D.M.3
  • 130
    • 84855496921 scopus 로고    scopus 로고
    • Retrotransposition is associated with genome instability during chronological aging
    • Maxwell PH, Burhans WC, Curcio MJ. 2011. Retrotransposition is associated with genome instability during chronological aging. Proc. Natl. Acad. Sci. USA 108(51):20376-81
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , Issue.51 , pp. 20376-20381
    • Maxwell, P.H.1    Burhans, W.C.2    Curcio, M.J.3
  • 131
    • 77958109197 scopus 로고    scopus 로고
    • Mechanisms of trinucleotide repeat instability during human development
    • McMurray CT. 2010. Mechanisms of trinucleotide repeat instability during human development. Nat. Rev. Genet. 11(11):786-99
    • (2010) Nat. Rev. Genet. , vol.11 , Issue.11 , pp. 786-799
    • McMurray, C.T.1
  • 132
    • 0141819143 scopus 로고    scopus 로고
    • An age-induced switch to a hyper-recombinational state
    • McMurray MA, Gottschling DE. 2003. An age-induced switch to a hyper-recombinational state. Science 301(5641):1908-11
    • (2003) Science , vol.301 , Issue.5641 , pp. 1908-1911
    • McMurray, M.A.1    Gottschling, D.E.2
  • 133
    • 57349093701 scopus 로고    scopus 로고
    • Role for perinuclear chromosome tethering in maintenance of genome stability
    • Mekhail K, Seebacher J, Gygi SP, Moazed D. 2008. Role for perinuclear chromosome tethering in maintenance of genome stability. Nature 456(7222):667-70
    • (2008) Nature , vol.456 , Issue.7222 , pp. 667-670
    • Mekhail, K.1    Seebacher, J.2    Gygi, S.P.3    Moazed, D.4
  • 134
    • 0031025093 scopus 로고    scopus 로고
    • DNA double-strand breaks caused by replication arrest
    • Michel B, Ehrlich SD, Uzest M. 1997. DNA double-strand breaks caused by replication arrest. EMBO J. 16(2):430-38
    • (1997) EMBO J. , vol.16 , Issue.2 , pp. 430-438
    • Michel, B.1    Ehrlich, S.D.2    Uzest, M.3
  • 135
    • 0032514711 scopus 로고    scopus 로고
    • Orientation-dependent and sequence-specific expansions of CTG/CAG trinucleotide repeats in Saccharomyces cerevisiae.Proc
    • Miret JJ, Pessoa-Brandão L, Lahue RS. 1998. Orientation-dependent and sequence-specific expansions of CTG/CAG trinucleotide repeats in Saccharomyces cerevisiae.Proc. Natl. Acad. Sci. USA 95(21):12438-43
    • (1998) Natl. Acad. Sci. USA , vol.95 , Issue.21 , pp. 12438-12443
    • Miret, J.J.1    Pessoa-Brandão, L.2    Lahue, R.S.3
  • 136
    • 12844265439 scopus 로고    scopus 로고
    • Mechanisms of transcription-replication collisions in bacteria
    • Mirkin EV, Mirkin SM. 2005. Mechanisms of transcription-replication collisions in bacteria. Mol. Cell. Biol. 25(3):888-95
    • (2005) Mol. Cell. Biol. , vol.25 , Issue.3 , pp. 888-895
    • Mirkin, E.V.1    Mirkin, S.M.2
  • 137
    • 78650727733 scopus 로고    scopus 로고
    • Yeast Sen1 helicase protects the genome from transcription-associated instability
    • Mischo HE, Gómez-González B, Grzechnik P, Rondón AG, Wei W, et al. 2011. Yeast Sen1 helicase protects the genome from transcription-associated instability. Mol. Cell 41(1):21-32
    • (2011) Mol. Cell , vol.41 , Issue.1 , pp. 21-32
    • Mischo, H.E.1    Gómez-González, B.2    Grzechnik, P.3    Rondón, A.G.4    Wei, W.5
  • 138
    • 72849150228 scopus 로고    scopus 로고
    • Nearby inverted repeats fuse to generate acentric and dicentric palindromic chromosomes by a replication template exchange mechanism
    • Mizuno K, Lambert S, Baldacci G, Murray JM, Carr AM. 2009. Nearby inverted repeats fuse to generate acentric and dicentric palindromic chromosomes by a replication template exchange mechanism. Genes Dev. 23(24):2876-86
    • (2009) Genes Dev. , vol.23 , Issue.24 , pp. 2876-2886
    • Mizuno, K.1    Lambert, S.2    Baldacci, G.3    Murray, J.M.4    Carr, A.M.5
  • 139
    • 72149119542 scopus 로고    scopus 로고
    • How the Fanconi anemia pathway guards the genome
    • Moldovan GL, D'Andrea AD. 2009. How the Fanconi anemia pathway guards the genome. Annu. Rev. Genet. 43:223-49
    • (2009) Annu. Rev. Genet. , vol.43 , pp. 223-249
    • Moldovan, G.L.1    D'Andrea, A.D.2
  • 140
    • 0024025259 scopus 로고
    • Spontaneous mitotic recombination in yeast: The hyper-recombinational rem1 mutations are alleles of the RAD3 gene
    • Montelone BA, Hoekstra MF, Malone RE. 1988. Spontaneous mitotic recombination in yeast: The hyper-recombinational rem1 mutations are alleles of the RAD3 gene. Genetics 119(2):289-301
    • (1988) Genetics , vol.119 , Issue.2 , pp. 289-301
    • Montelone, B.A.1    Hoekstra, M.F.2    Malone, R.E.3
  • 141
    • 77649264634 scopus 로고    scopus 로고
    • A postincision-deficient TFIIH causes replication fork breakage and uncovers alternative Rad51-or Pol32-mediated restart mechanisms
    • Moriel-Carretero M, Aguilera A. 2010. A postincision-deficient TFIIH causes replication fork breakage and uncovers alternative Rad51-or Pol32-mediated restart mechanisms. Mol. Cell 37(5):690-701
    • (2010) Mol. Cell , vol.37 , Issue.5 , pp. 690-701
    • Moriel-Carretero, M.1    Aguilera, A.2
  • 142
    • 84873494530 scopus 로고    scopus 로고
    • Histone H3K56 acetylation, Rad52, and non-DNA repair factors control double-strand break repair choice with the sister chromatid
    • Muñoz-Galván S, Jimeno S, Rothstein R, Aguilera A. 2013. Histone H3K56 acetylation, Rad52, and non-DNA repair factors control double-strand break repair choice with the sister chromatid. PLoS Genet. 9(1):e1003237
    • (2013) PLoS Genet. , vol.9 , Issue.1
    • Muñoz-Galván, S.1    Jimeno, S.2    Rothstein, R.3    Aguilera, A.4
  • 143
    • 68149161607 scopus 로고    scopus 로고
    • A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging
    • Murga M, Bunting S, Montaña MF, Soria R, Mulero F, et al. 2009. A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging. Nat. Genet. 41(8):891-98
    • (2009) Nat. Genet. , vol.41 , Issue.8 , pp. 891-898
    • Murga, M.1    Bunting, S.2    Montaña, M.F.3    Soria, R.4    Mulero, F.5
  • 144
    • 0035963338 scopus 로고    scopus 로고
    • Multiple pathways cooperate in the suppression of genome instability in Saccharomyces cerevisiae
    • Myung K, Chen C, Kolodner RD. 2001. Multiple pathways cooperate in the suppression of genome instability in Saccharomyces cerevisiae. Nature 411(6841):1073-76
    • (2001) Nature , vol.411 , Issue.6841 , pp. 1073-1076
    • Myung, K.1    Chen, C.2    Kolodner, R.D.3
  • 145
    • 0035830498 scopus 로고    scopus 로고
    • Suppression of spontaneous chromosomal rearrangements by S phase checkpoint functions in Saccharomyces cerevisiae
    • Myung K, Datta A, Kolodner RD. 2001. Suppression of spontaneous chromosomal rearrangements by S phase checkpoint functions in Saccharomyces cerevisiae. Cell 104(3):397-408
    • (2001) Cell , vol.104 , Issue.3 , pp. 397-408
    • Myung, K.1    Datta, A.2    Kolodner, R.D.3
  • 146
    • 0037007074 scopus 로고    scopus 로고
    • Suppression of genome instability by redundant S-phase checkpoint pathways in Saccharomyces cerevisiae
    • Myung K, Kolodner RD. 2002. Suppression of genome instability by redundant S-phase checkpoint pathways in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 99(7):4500-7
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , Issue.7 , pp. 4500-4507
    • Myung, K.1    Kolodner, R.D.2
  • 147
    • 67349187702 scopus 로고    scopus 로고
    • The FANC pathway and BLM collaborate during mitosis to prevent micro-nucleation and chromosome abnormalities
    • Naim V, Rosselli F. 2009. The FANC pathway and BLM collaborate during mitosis to prevent micro-nucleation and chromosome abnormalities. Nat. Cell Biol. 11(6):761-68
    • (2009) Nat. Cell Biol. , vol.11 , Issue.6 , pp. 761-768
    • Naim, V.1    Rosselli, F.2
  • 148
    • 0026446059 scopus 로고
    • Transcription enhances intrachromosomal homologous recombination in mammalian cells
    • Nickoloff JA. 1992. Transcription enhances intrachromosomal homologous recombination in mammalian cells. Mol. Cell. Biol. 12(12):5311-18
    • (1992) Mol. Cell. Biol. , vol.12 , Issue.12 , pp. 5311-5318
    • Nickoloff, J.A.1
  • 149
    • 30144436775 scopus 로고    scopus 로고
    • Common chromosomal fragile sites and cancer: Focus on FRA16D
    • O'Keefe LV, Richards RI. 2006. Common chromosomal fragile sites and cancer: focus on FRA16D. Cancer Lett. 232(1):37-47
    • (2006) Cancer Lett. , vol.232 , Issue.1 , pp. 37-47
    • O'Keefe, L.V.1    Richards, R.I.2
  • 150
    • 79959885574 scopus 로고    scopus 로고
    • Failure of origin activation in response to fork stalling leads to chromosomal instability at fragile sites
    • Ozeri-Galai E, Lebofsky R, Rahat A, Bester AC, Bensimon A, Kerem B. 2011. Failure of origin activation in response to fork stalling leads to chromosomal instability at fragile sites. Mol. Cell 43(1):122-31
    • (2011) Mol. Cell , vol.43 , Issue.1 , pp. 122-131
    • Ozeri-Galai, E.1    Lebofsky, R.2    Rahat, A.3    Bester, A.C.4    Bensimon, A.5    Kerem, B.6
  • 151
    • 72849116104 scopus 로고    scopus 로고
    • Fusion of nearby inverted repeats by a replication-based mechanism leads to formation of dicentric and acentric chromosomes that cause genome instability in budding yeast
    • Paek AL, Kaochar S, Jones H, Elezaby A, Shanks L, Weinert T. 2009. Fusion of nearby inverted repeats by a replication-based mechanism leads to formation of dicentric and acentric chromosomes that cause genome instability in budding yeast. Genes Dev. 23(24):2861-75
    • (2009) Genes Dev. , vol.23 , Issue.24 , pp. 2861-2875
    • Paek, A.L.1    Kaochar, S.2    Jones, H.3    Elezaby, A.4    Shanks, L.5    Weinert, T.6
  • 152
    • 79957556530 scopus 로고    scopus 로고
    • DNA replication through G-quadruplex motifs is promoted by the Saccharomyces cerevisiae Pif1 DNA helicase
    • Paeschke K, Capra JA, Zakian VA. 2011. DNA replication through G-quadruplex motifs is promoted by the Saccharomyces cerevisiae Pif1 DNA helicase. Cell 145(5):678-91
    • (2011) Cell , vol.145 , Issue.5 , pp. 678-691
    • Paeschke, K.1    Capra, J.A.2    Zakian, V.A.3
  • 153
    • 0037799191 scopus 로고    scopus 로고
    • Uncoupling of leading-and lagging-strand DNA replication during lesion bypass in vivo
    • Pagès V, Fuchs RP. 2003. Uncoupling of leading-and lagging-strand DNA replication during lesion bypass in vivo. Science 300(5623):1300-3
    • (2003) Science , vol.300 , Issue.5623 , pp. 1300-1303
    • Pagès, V.1    Fuchs, R.P.2
  • 154
    • 67651119997 scopus 로고    scopus 로고
    • A genome-wide siRNA screen reveals diverse cellular processes and pathways that mediate genome stability
    • Paulsen RD, Soni DV, Wollman R, Hahn AT, Yee M-C, et al. 2009. A genome-wide siRNA screen reveals diverse cellular processes and pathways that mediate genome stability. Mol. Cell 35(2):228-39
    • (2009) Mol. Cell , vol.35 , Issue.2 , pp. 228-239
    • Paulsen, R.D.1    Soni, D.V.2    Wollman, R.3    Hahn, A.T.4    Yee, M.-C.5
  • 155
  • 156
    • 33847775919 scopus 로고    scopus 로고
    • Upregulation of error-prone DNA polymerases ß and K slows down fork progression without activating the replication checkpoint
    • Pillaire MJ, Betous R, Conti C, Czaplicki J, Pasero P, et al. 2007. Upregulation of error-prone DNA polymerases ß and K slows down fork progression without activating the replication checkpoint. Cell Cycle 6(4):471-77
    • (2007) Cell Cycle , vol.6 , Issue.4 , pp. 471-477
    • Pillaire, M.J.1    Betous, R.2    Conti, C.3    Czaplicki, J.4    Pasero, P.5
  • 157
    • 84857060479 scopus 로고    scopus 로고
    • DNTP pools determine fork progression and origin usage under replication stress
    • Poli J, Tsaponina O, Crabbé L, Keszthelyi A, Pantesco V, et al. 2012. dNTP pools determine fork progression and origin usage under replication stress. EMBO J. 31(4):883-94
    • (2012) EMBO J. , vol.31 , Issue.4 , pp. 883-894
    • Poli, J.1    Tsaponina, O.2    Crabbé, L.3    Keszthelyi, A.4    Pantesco, V.5
  • 158
    • 57649129186 scopus 로고    scopus 로고
    • The replisome uses mRNA as a primer after colliding with RNA polymerase
    • Pomerantz RT, O'Donnell M. 2008. The replisome uses mRNA as a primer after colliding with RNA polymerase. Nature 456(7223):762-66
    • (2008) Nature , vol.456 , Issue.7223 , pp. 762-766
    • Pomerantz, R.T.1    O'Donnell, M.2
  • 159
    • 75749150810 scopus 로고    scopus 로고
    • Direct restart of a replication fork stalled by a head-on RNA polymerase
    • Pomerantz RT, O'Donnell M. 2010. Direct restart of a replication fork stalled by a head-on RNA polymerase. Science 327(5965):590-92
    • (2010) Science , vol.327 , Issue.5965 , pp. 590-592
    • Pomerantz, R.T.1    O'Donnell, M.2
  • 160
    • 13444270604 scopus 로고    scopus 로고
    • Partial depletion of histone H4 increases homologous recombination- mediated genetic instability
    • Prado F, Aguilera A. 2005. Partial depletion of histone H4 increases homologous recombination-mediated genetic instability. Mol. Cell. Biol. 25(4):1526-36
    • (2005) Mol. Cell. Biol. , vol.25 , Issue.4 , pp. 1526-1536
    • Prado, F.1    Aguilera, A.2
  • 161
    • 17144426028 scopus 로고    scopus 로고
    • Impairment of replication fork progression mediates RNA polII transcription-associated recombination
    • Prado F, Aguilera A. 2005. Impairment of replication fork progression mediates RNA polII transcription-associated recombination. EMBO J. 24(6):1267-76
    • (2005) EMBO J. , vol.24 , Issue.6 , pp. 1267-1276
    • Prado, F.1    Aguilera, A.2
  • 165
    • 67149126812 scopus 로고    scopus 로고
    • The yeast Pif1 helicase prevents genomic instability caused by G-quadruplex-forming CEB1 sequences in vivo
    • Ribeyre C, Lopes J, Boulé JB, Piazza A, Guédin A, et al. 2009. The yeast Pif1 helicase prevents genomic instability caused by G-quadruplex-forming CEB1 sequences in vivo. PLoS Genet. 5(5):e1000475
    • (2009) PLoS Genet. , vol.5 , Issue.5
    • Ribeyre, C.1    Lopes, J.2    Boulé, J.B.3    Piazza, A.4    Guédin, A.5
  • 166
    • 0030664357 scopus 로고    scopus 로고
    • Dynamic mutation: Possible mechanisms and significance in human disease
    • Richards RI, Sutherland GR. 1997. Dynamic mutation: possible mechanisms and significance in human disease. Trends Biochem. Sci. 22(11):432-36
    • (1997) Trends Biochem. Sci. , vol.22 , Issue.11 , pp. 432-436
    • Richards, R.I.1    Sutherland, G.R.2
  • 167
    • 70449641054 scopus 로고    scopus 로고
    • AID produces DNA double-strand breaks in non-Ig genes and mature B cell lymphomas with reciprocal chromosome translocations
    • Robbiani DF, Bunting S, Feldhahn N, Bothmer A, Camps J, et al. 2009. AID produces DNA double-strand breaks in non-Ig genes and mature B cell lymphomas with reciprocal chromosome translocations. Mol. Cell 36(4):631-41
    • (2009) Mol. Cell , vol.36 , Issue.4 , pp. 631-641
    • Robbiani, D.F.1    Bunting, S.2    Feldhahn, N.3    Bothmer, A.4    Camps, J.5
  • 168
    • 79952266545 scopus 로고    scopus 로고
    • AID induces double-strand breaks at immunoglobulin switch regions and c-MYC causing chromosomal translocations in yeast THO mutants
    • Ruiz JF, Gomez-Gonzalez B, Aguilera A. 2011. AID induces double-strand breaks at immunoglobulin switch regions and c-MYC causing chromosomal translocations in yeast THO mutants. PLoS Genet. 7(2):e1002009
    • (2011) PLoS Genet. , vol.7 , Issue.2
    • Ruiz, J.F.1    Gomez-Gonzalez, B.2    Aguilera, A.3
  • 169
    • 84858315982 scopus 로고    scopus 로고
    • DNA replication through hard-to-replicate sites, including both highly transcribed RNA Pol II and Pol III genes, requires the S
    • Sabouri N, McDonald KR, Webb CJ, Cristea IM, Zakian VA. 2012. DNA replication through hard-to-replicate sites, including both highly transcribed RNA Pol II and Pol III genes, requires the S. pombe Pfh1 helicase. Genes Dev. 26(6):581-93
    • (2012) Pombe Pfh1 Helicase. Genes Dev. , vol.26 , Issue.6 , pp. 581-593
    • Sabouri, N.1    McDonald, K.R.2    Webb, C.J.3    Cristea, I.M.4    Zakian, V.A.5
  • 170
    • 77149135723 scopus 로고    scopus 로고
    • ATR activation and replication fork restart are defective in FANCM-deficient cells
    • Schwab RA, Blackford AN, Niedzwiedz W. 2010. ATR activation and replication fork restart are defective in FANCM-deficient cells. EMBO J. 29(4):806-18
    • (2010) EMBO J. , vol.29 , Issue.4 , pp. 806-818
    • Schwab, R.A.1    Blackford, A.N.2    Niedzwiedz, W.3
  • 171
    • 27744496209 scopus 로고    scopus 로고
    • Homologous recombination and nonhomologous end-joining repair pathways regulate fragile site stability
    • Schwartz M, Zlotorynski E, Goldberg M, Ozeri E, Rahat A, et al. 2005. Homologous recombination and nonhomologous end-joining repair pathways regulate fragile site stability. Genes Dev. 19(22):2715-26
    • (2005) Genes Dev. , vol.19 , Issue.22 , pp. 2715-2726
    • Schwartz, M.1    Zlotorynski, E.2    Goldberg, M.3    Ozeri, E.4    Rahat, A.5
  • 172
    • 0031965224 scopus 로고    scopus 로고
    • Expansions of CAG repeat tracts are frequent in a yeast mutant defective in Okazaki fragment maturation
    • Schweitzer JK, Livingston DM. 1998. Expansions of CAG repeat tracts are frequent in a yeast mutant defective in Okazaki fragment maturation. Hum. Mol. Genet. 7(1):69-74
    • (1998) Hum. Mol. Genet. , vol.7 , Issue.1 , pp. 69-74
    • Schweitzer, J.K.1    Livingston, D.M.2
  • 173
    • 0032582794 scopus 로고    scopus 로고
    • RuvAB acts at arrested replication forks
    • Seigneur M, Bidnenko V, Ehrlich SD, Michel B. 1998. RuvAB acts at arrested replication forks. Cell 95(3):419-30
    • (1998) Cell , vol.95 , Issue.3 , pp. 419-430
    • Seigneur, M.1    Bidnenko, V.2    Ehrlich, S.D.3    Michel, B.4
  • 174
    • 67649635974 scopus 로고    scopus 로고
    • Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication
    • Sfeir A, Kosiyatrakul ST, Hockemeyer D, MacRae SL, Karlseder J, et al. 2009. Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication. Cell 138(1):90-103
    • (2009) Cell , vol.138 , Issue.1 , pp. 90-103
    • Sfeir, A.1    Kosiyatrakul, S.T.2    Hockemeyer, D.3    MacRae, S.L.4    Karlseder, J.5
  • 176
    • 3242670803 scopus 로고    scopus 로고
    • ATR and ATM regulate the timing of DNA replication origin firing
    • Shechter D, Costanzo V, Gautier J. 2004. ATR and ATM regulate the timing of DNA replication origin firing. Nat. Cell Biol. 6(7):648-55
    • (2004) Nat. Cell Biol. , vol.6 , Issue.7 , pp. 648-655
    • Shechter, D.1    Costanzo, V.2    Gautier, J.3
  • 177
    • 33845877445 scopus 로고    scopus 로고
    • A viable allele of Mcm4 causes chromosome instability and mammary adenocarcinomas in mice
    • Shima N, Alcaraz A, Liachko I, Buske TR, Andrews CA, et al. 2007. A viable allele of Mcm4 causes chromosome instability and mammary adenocarcinomas in mice. Nat. Genet. 39(1):93-98
    • (2007) Nat. Genet. , vol.39 , Issue.1 , pp. 93-98
    • Shima, N.1    Alcaraz, A.2    Liachko, I.3    Buske, T.R.4    Andrews, C.A.5
  • 178
    • 67649639511 scopus 로고    scopus 로고
    • Large-scale expansions of Friedreich's ataxia GAA repeats in yeast
    • Shishkin AA, Voineagu I, Matera R, Cherng N, Chernet BT, et al. 2009. Large-scale expansions of Friedreich's ataxia GAA repeats in yeast. Mol. Cell 35(1):82-92
    • (2009) Mol. Cell , vol.35 , Issue.1 , pp. 82-92
    • Shishkin, A.A.1    Voineagu, I.2    Matera, R.3    Cherng, N.4    Chernet, B.T.5
  • 179
    • 84862776917 scopus 로고    scopus 로고
    • Intrinsic coupling of lagging-strand synthesis to chromatin assembly
    • Smith DJ, Whitehouse I. 2012. Intrinsic coupling of lagging-strand synthesis to chromatin assembly. Nature 483(7390):434-38
    • (2012) Nature , vol.483 , Issue.7390 , pp. 434-438
    • Smith, D.J.1    Whitehouse, I.2
  • 180
    • 80051632086 scopus 로고    scopus 로고
    • Ultrafine anaphase bridges, broken DNA and illegitimate recombination induced by a replication fork barrier
    • Sofueva S, Osman F, Lorenz A, Steinacher R, Castagnetti S, et al. 2011. Ultrafine anaphase bridges, broken DNA and illegitimate recombination induced by a replication fork barrier. Nucleic Acids Res. 39(15):6568-84
    • (2011) Nucleic Acids Res. , vol.39 , Issue.15 , pp. 6568-6584
    • Sofueva, S.1    Osman, F.2    Lorenz, A.3    Steinacher, R.4    Castagnetti, S.5
  • 181
    • 0037178740 scopus 로고    scopus 로고
    • Fork reversal and ssDNA accumulation at stalled replication forks owing to checkpoint defects
    • Sogo JM, Lopes M, Foiani M. 2002. Fork reversal and ssDNA accumulation at stalled replication forks owing to checkpoint defects. Science 297(5581):599-602
    • (2002) Science , vol.297 , Issue.5581 , pp. 599-602
    • Sogo, J.M.1    Lopes, M.2    Foiani, M.3
  • 182
    • 84863747679 scopus 로고    scopus 로고
    • MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity
    • Stehling O, Vashisht AA, Mascarenhas J, Jonsson ZO, Sharma T, et al. 2012. MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity. Science 337(6091):195-99
    • (2012) Science , vol.337 , Issue.6091 , pp. 195-199
    • Stehling, O.1    Vashisht, A.A.2    Mascarenhas, J.3    Jonsson, Z.O.4    Sharma, T.5
  • 183
    • 84858330322 scopus 로고    scopus 로고
    • The DNA helicase Pfh1 promotes fork merging at replication termination sites to ensure genome stability
    • Steinacher R, Osman F, Dalgaard JZ, Lorenz A, Whitby MC. 2012. The DNA helicase Pfh1 promotes fork merging at replication termination sites to ensure
    • (2012) Genes Dev. , vol.26 , Issue.6 , pp. 594-602
    • Steinacher, R.1    Osman, F.2    Dalgaard, J.Z.3    Lorenz, A.4    Whitby, M.C.5
  • 184
    • 84856253456 scopus 로고    scopus 로고
    • R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutants
    • Stirling PC, Chan YA, Minaker SW, Aristizabal MJ, Barrett I, et al. 2012. R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutants. Genes Dev. 26(2):163-75
    • (2012) Genes Dev. , vol.26 , Issue.2 , pp. 163-175
    • Stirling, P.C.1    Chan, Y.A.2    Minaker, S.W.3    Aristizabal, M.J.4    Barrett, I.5
  • 185
    • 20244388673 scopus 로고    scopus 로고
    • Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage
    • Syljuåsen RG, Sørensen CS, Hansen LT, Fugger K, Lundin C, et al. 2005. Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage. Mol. Cell. Biol. 25(9):3553-62
    • (2005) Mol. Cell. Biol. , vol.25 , Issue.9 , pp. 3553-3562
    • Syljuåsen, R.G.1    Sørensen, C.S.2    Hansen, L.T.3    Fugger, K.4    Lundin, C.5
  • 186
    • 77949275845 scopus 로고    scopus 로고
    • Systematic identification of fragile sites via genome-wide location analysis of γ-H2AX
    • Szilard RK, Jacques PE, Laramée L, Cheng B, Galicia S, et al. 2010. Systematic identification of fragile sites via genome-wide location analysis of γ-H2AX. Nat. Struct. Mol. Biol. 17(3):299-305
    • (2010) Nat. Struct. Mol. Biol. , vol.17 , Issue.3 , pp. 299-305
    • Szilard, R.K.1    Jacques, P.E.2    Laramée, L.3    Cheng, B.4    Galicia, S.5
  • 187
    • 0042420304 scopus 로고    scopus 로고
    • DNA damage foci at dysfunctional telomeres
    • Takai H, Smogorzewska A, de Lange T. 2003. DNA damage foci at dysfunctional telomeres. Curr. Biol. 13(17):1549-56
    • (2003) Curr. Biol. , vol.13 , Issue.17 , pp. 1549-1556
    • Takai, H.1    Smogorzewska, A.2    De Lange, T.3
  • 188
    • 79959820842 scopus 로고    scopus 로고
    • Multiple regulatory mechanisms to inhibit untimely initiation of DNA replication are important for stable genome maintenance
    • Tanaka S, Araki H. 2011. Multiple regulatory mechanisms to inhibit untimely initiation of DNA replication are important for stable genome maintenance. PLoS Genet. 7(6):e1002136
    • (2011) PLoS Genet. , vol.7 , Issue.6
    • Tanaka, S.1    Araki, H.2
  • 189
    • 0037107343 scopus 로고    scopus 로고
    • Deregulated G1-cyclin expression induces genomic instability by preventing efficient pre-RC formation
    • Tanaka S, Diffley JFX. 2002. Deregulated G1-cyclin expression induces genomic instability by preventing efficient pre-RC formation. Genes Dev. 16(20):2639-49
    • (2002) Genes Dev. , vol.16 , Issue.20 , pp. 2639-2649
    • Tanaka, S.1    Diffley, J.F.X.2
  • 190
    • 77952527102 scopus 로고    scopus 로고
    • The transcription factor DksA prevents conflicts between DNA replication and transcription machinery
    • Tehranchi AK, Blankschien MD, Zhang Y, Halliday JA, Srivatsan A, et al. 2010. The transcription factor DksA prevents conflicts between DNA replication and transcription machinery. Cell 141(4):595-605
    • (2010) Cell , vol.141 , Issue.4 , pp. 595-605
    • Tehranchi, A.K.1    Blankschien, M.D.2    Zhang, Y.3    Halliday, J.A.4    Srivatsan, A.5
  • 191
    • 0024977417 scopus 로고
    • Elevated recombination rates in transcriptionally active DNA
    • Thomas BJ, Rothstein R. 1989. Elevated recombination rates in transcriptionally active DNA. Cell 56(4):619-30
    • (1989) Cell , vol.56 , Issue.4 , pp. 619-630
    • Thomas, B.J.1    Rothstein, R.2
  • 192
    • 0031442653 scopus 로고    scopus 로고
    • A novel mutation avoidance mechanism dependent on S cerevisiae RAD27 is distinct from DNA mismatch repair
    • Tishkoff DX, Filosi N, Gaida GM, Kolodner RD. 1997. A novel mutation avoidance mechanism dependent on S cerevisiae RAD27 is distinct from DNA mismatch repair. Cell 88(2):253-63
    • (1997) Cell , vol.88 , Issue.2 , pp. 253-263
    • Tishkoff, D.X.1    Filosi, N.2    Gaida, G.M.3    Kolodner, R.D.4
  • 193
    • 84867399846 scopus 로고    scopus 로고
    • Cohesin association to replication sites depends on rad50 and promotes fork restart
    • Tittel-Elmer M, Lengronne A, Davidson MB, Bacal J, François P, et al. 2012. Cohesin association to replication sites depends on rad50 and promotes fork restart. Mol. Cell 48(1):98-108
    • (2012) Mol. Cell , vol.48 , Issue.1 , pp. 98-108
    • Tittel-Elmer, M.1    Lengronne, A.2    Davidson, M.B.3    Bacal, J.4    François, P.5
  • 194
    • 34547591933 scopus 로고    scopus 로고
    • The Smc5-Smc6 complex and SUMO modification of Rad52 regulates recombinational repair at the ribosomal gene locus
    • Torres-Rosell J, Sunjevaric I, De Piccoli G, Sacher M, Eckert-Boulet N, et al. 2007. The Smc5-Smc6 complex and SUMO modification of Rad52 regulates recombinational repair at the ribosomal gene locus. Nat. Cell Biol. 9(8):923-31
    • (2007) Nat. Cell Biol. , vol.9 , Issue.8 , pp. 923-931
    • Torres-Rosell, J.1    Sunjevaric, I.2    De Piccoli, G.3    Sacher, M.4    Eckert-Boulet, N.5
  • 195
    • 24044552287 scopus 로고    scopus 로고
    • Mrc1 and Tof1 promote replication fork progression and recovery independently of Rad53
    • Tourrière H, Versini G, Cordón-Preciado V, Alabert C, Pasero P. 2005. Mrc1 and Tof1 promote replication fork progression and recovery independently of Rad53. Mol. Cell 19(5):699-706
    • (2005) Mol. Cell , vol.19 , Issue.5 , pp. 699-706
    • Tourrière, H.1    Versini, G.2    Cordón-Preciado, V.3    Alabert, C.4    Pasero, P.5
  • 196
    • 22544464455 scopus 로고    scopus 로고
    • RNA polymerase modulators and DNA repair activities resolve conflicts between DNA replication and transcription
    • Trautinger BW, Jaktaji RP, Rusakova E, Lloyd RG. 2005. RNA polymerase modulators and DNA repair activities resolve conflicts between DNA replication and transcription. Mol. Cell 19(2):247-58
    • (2005) Mol. Cell , vol.19 , Issue.2 , pp. 247-258
    • Trautinger, B.W.1    Jaktaji, R.P.2    Rusakova, E.3    Lloyd, R.G.4
  • 197
    • 70449522304 scopus 로고    scopus 로고
    • Topoisomerase i suppresses genomic instability by preventing interference between replication and transcription
    • Tuduri S, Crabbé L, Conti C, Tourrière H, Holtgreve-Grez H, et al. 2009. Topoisomerase I suppresses genomic instability by preventing interference between replication and transcription. Nat. Cell Biol. 11(11):1315-24
    • (2009) Nat. Cell Biol. , vol.11 , Issue.11 , pp. 1315-1324
    • Tuduri, S.1    Crabbé, L.2    Conti, C.3    Tourrière, H.4    Holtgreve-Grez, H.5
  • 198
    • 0031960691 scopus 로고    scopus 로고
    • Genetic analysis of yeast RPA1 reveals its multiple functions in DNA metabolism
    • Umezu K, Sugawara N, Chen C, Haber JE, Kolodner RD. 1998. Genetic analysis of yeast RPA1 reveals its multiple functions in DNA metabolism. Genetics 148(3):989-1005
    • (1998) Genetics , vol.148 , Issue.3 , pp. 989-1005
    • Umezu, K.1    Sugawara, N.2    Chen, C.3    Haber, J.E.4    Kolodner, R.D.5
  • 199
    • 84860854071 scopus 로고    scopus 로고
    • RTEL1 dismantles T loops and counteracts telomeric G4-DNA to maintain telomere integrity
    • Vannier JB, Pavicic-Kaltenbrunner V, Petalcorin MIR, Ding H, Boulton SJ. 2012. RTEL1 dismantles T loops and counteracts telomeric G4-DNA to maintain telomere integrity. Cell 149(4):795-806
    • (2012) Cell , vol.149 , Issue.4 , pp. 795-806
    • Vannier, J.B.1    Pavicic-Kaltenbrunner, V.2    Petalcorin, M.I.R.3    Ding, H.4    Boulton, S.J.5
  • 200
    • 0032489012 scopus 로고    scopus 로고
    • TRF2 protects human telomeres from end-to-end fusions
    • van Steensel B, Smogorzewska A, de Lange T. 1998. TRF2 protects human telomeres from end-to-end fusions. Cell 92(3):401-13
    • (1998) Cell , vol.92 , Issue.3 , pp. 401-413
    • Van Steensel, B.1    Smogorzewska, A.2    De Lange, T.3
  • 201
    • 0026688590 scopus 로고
    • DNA transcription and repressor binding affect deletion formation in Escherichia coli plasmids
    • Vilette D, Uzest M, Ehrlich SD, Michel B. 1992. DNA transcription and repressor binding affect deletion formation in Escherichia coli plasmids. EMBO J. 11(10):3629-34
    • (1992) EMBO J. , vol.11 , Issue.10 , pp. 3629-3634
    • Vilette, D.1    Uzest, M.2    Ehrlich, S.D.3    Michel, B.4
  • 202
    • 0023666141 scopus 로고
    • Recombination-stimulating sequences in yeast ribosomal DNA correspond to sequences regulating transcription by RNA polymerase i
    • Voelkel-Meiman K, Keil RL, Roeder GS. 1987. Recombination-stimulating sequences in yeast ribosomal DNA correspond to sequences regulating transcription by RNA polymerase I. Cell 48(6):1071-79
    • (1987) Cell , vol.48 , Issue.6 , pp. 1071-1079
    • Voelkel-Meiman, K.1    Keil, R.L.2    Roeder, G.S.3
  • 203
    • 0025237488 scopus 로고
    • A chromosome containing HOT1 preferentially receives information during mitotic interchromosomal gene conversion
    • Voelkel-Meiman K, Roeder GS. 1990. A chromosome containing HOT1 preferentially receives information during mitotic interchromosomal gene conversion. Genetics 124(3):561-72
    • (1990) Genetics , vol.124 , Issue.3 , pp. 561-572
    • Voelkel-Meiman, K.1    Roeder, G.S.2
  • 204
    • 59649105477 scopus 로고    scopus 로고
    • Replisome stalling and stabilization at CGG repeats, which are responsible for chromosomal fragility
    • Voineagu I, Surka CF, Shishkin AA, Krasilnikova MM, Mirkin SM. 2009. Replisome stalling and stabilization at CGG repeats, which are responsible for chromosomal fragility. Nat. Struct. Mol. Biol. 16(2):226-28
    • (2009) Nat. Struct. Mol. Biol. , vol.16 , Issue.2 , pp. 226-228
    • Voineagu, I.1    Surka, C.F.2    Shishkin, A.A.3    Krasilnikova, M.M.4    Mirkin, S.M.5
  • 205
    • 84255177502 scopus 로고    scopus 로고
    • RNase H and multiple RNA biogenesis factors cooperate to prevent RNA:DNA hybrids from generating genome instability
    • Wahba L, Amon JD, Koshland D, Vuica-Ross M. 2011. RNase H and multiple RNA biogenesis factors cooperate to prevent RNA:DNA hybrids from generating genome instability. Mol. Cell 44(6):978-88
    • (2011) Mol. Cell , vol.44 , Issue.6 , pp. 978-988
    • Wahba, L.1    Amon, J.D.2    Koshland, D.3    Vuica-Ross, M.4
  • 206
    • 22844436867 scopus 로고    scopus 로고
    • Mutation in Rpa1resultsindefective DNA double-strand break repair, chromosomal instability and cancer in mice
    • Wang Y, Putnam CD, Kane MF, Zhang W, Edelmann L, et al. 2005. Mutation in Rpa1resultsindefective DNA double-strand break repair, chromosomal instability and cancer in mice. Nat. Genet. 37(7):750-55
    • (2005) Nat. Genet. , vol.37 , Issue.7 , pp. 750-755
    • Wang, Y.1    Putnam, C.D.2    Kane, M.F.3    Zhang, W.4    Edelmann, L.5
  • 207
    • 79953239469 scopus 로고    scopus 로고
    • Aberrant chromosome morphology in human cells defective for Holliday junction resolution
    • Wechsler T, Newman S, West SC. 2011. Aberrant chromosome morphology in human cells defective for Holliday junction resolution. Nature 471(7340):642-46
    • (2011) Nature , vol.471 , Issue.7340 , pp. 642-646
    • Wechsler, T.1    Newman, S.2    West, S.C.3
  • 208
    • 33645823661 scopus 로고    scopus 로고
    • Replication fork progression is impaired by transcription in hyperrecombinant yeast cells lacking a functional THO complex
    • Wellinger RE, Prado F, Aguilera A. 2006. Replication fork progression is impaired by transcription in hyperrecombinant yeast cells lacking a functional THO complex. Mol. Cell. Biol. 26(8):3327-34
    • (2006) Mol. Cell. Biol. , vol.26 , Issue.8 , pp. 3327-3334
    • Wellinger, R.E.1    Prado, F.2    Aguilera, A.3
  • 209
    • 0025806273 scopus 로고
    • Mcm2 and Mcm3, two proteins important for ARS activity, are related in structure and function
    • Yan H, Gibson S, Tye BK. 1991. Mcm2 and Mcm3, two proteins important for ARS activity, are related in structure and function. Genes Dev. 5(6):944-57
    • (1991) Genes Dev. , vol.5 , Issue.6 , pp. 944-957
    • Yan, H.1    Gibson, S.2    Tye, B.K.3
  • 210
    • 0037291295 scopus 로고    scopus 로고
    • Defective S phase chromatin assembly causes DNA damage, activation of the S phase checkpoint, and S phase arrest
    • Ye X, Franco AA, Santos H, Nelson DM, Kaufman PD, Adams PD. 2003. Defective S phase chromatin assembly causes DNA damage, activation of the S phase checkpoint, and S phase arrest. Mol. Cell 11(2):341-51
    • (2003) Mol. Cell , vol.11 , Issue.2 , pp. 341-351
    • Ye, X.1    Franco, A.A.2    Santos, H.3    Nelson, D.M.4    Kaufman, P.D.5    Adams, P.D.6
  • 211
    • 80054091679 scopus 로고    scopus 로고
    • The Escherichia coli replisome is inherently DNA damage tolerant
    • Yeeles JTP, Marians KJ. 2011. The Escherichia coli replisome is inherently DNA damage tolerant. Science 334(6053):235-38
    • (2011) Science , vol.334 , Issue.6053 , pp. 235-238
    • Yeeles, J.T.P.1    Marians, K.J.2
  • 212
    • 0037650190 scopus 로고    scopus 로고
    • R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells
    • Yu K, Chédin F, Hsieh C-L, Wilson TE, Lieber MR. 2003. R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells. Nat. Immunol. 4(5):442-51
    • (2003) Nat. Immunol. , vol.4 , Issue.5 , pp. 442-451
    • Yu, K.1    Chédin, F.2    Hsieh, C.-L.3    Wilson, T.E.4    Lieber, M.R.5
  • 213
    • 0017905113 scopus 로고
    • Recombinant levels of Escherichia coli K-12 mutants deficient in various replication, recombination, or repair genes
    • Zieg J, Maples VF, Kushner SR. 1978. Recombinant levels of Escherichia coli K-12 mutants deficient in various replication, recombination, or repair genes. J. Bacteriol. 134(3):958-66
    • (1978) J. Bacteriol. , vol.134 , Issue.3 , pp. 958-966
    • Zieg, J.1    Maples, V.F.2    Kushner, S.R.3


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