Stepwise Activation of the ATR Signaling Pathway upon Increasing Replication Stress Impacts Fragile Site Integrity

PLoS Genetics

Volumn 9, Issue 7, 2013, Pages

  Koundrioukoff, Stéphane ^a   Carignon, Sandra ^a   Técher, Hervé ^a   Letessier, Anne ^a   Brison, Olivier ^a   Debatisse, Michelle ^a  

^a Institut Curie   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ATR PROTEIN; CHECKPOINT KINASE 1; MRE11 PROTEIN; PROTEIN P53; SINGLE STRANDED DNA;

ARTICLE; CELL CYCLE PROGRESSION; CELL CYCLE S PHASE; CELL TYPE; CHROMATIN; COMMON FRAGILE SITE; CONTROLLED STUDY; FIBROBLAST; GENETIC TRANSFECTION; GENOMIC INSTABILITY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOCHEMISTRY; LYMPHOCYTE; METAPHASE; MITOSIS; SENSOR; SIGNAL TRANSDUCTION; STRESS;

ATAXIA TELANGIECTASIA MUTATED PROTEINS; CELL CYCLE PROTEINS; CELL LINE; CHROMATIN; CHROMOSOME FRAGILE SITES; DNA REPLICATION; FIBROBLASTS; GENOMIC INSTABILITY; HUMANS; LYMPHOCYTES; MITOSIS; PROTEIN KINASES; REPLICATION ORIGIN; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84880784164     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1003643     Document Type: Article

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