The secret life of Bcl-2: Apoptosis-independent inhibition of DNA repair by Bcl-2 family members

Mutation Research - Reviews in Mutation Research

Volumn 751, Issue 2, 2012, Pages 247-257

  Laulier, Corentin ^b,c   Lopez, Bernard S ^a,b  

^a INSTITUT GUSTAVE ROUSSY   (France)

^b INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE   (France)

^c CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

Apoptosis; Bcl 2; BRCA1; DNA repair; Double strand break repair; Homologous recombination

Indexed keywords

ANTIBODY; BH3 PROTEIN; BIM PROTEIN; BRCA1 PROTEIN; CASPASE; CYTOCHROME C; DOUBLE STRANDED DNA; KU ANTIGEN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; PROTEIN; PROTEIN APE1; PROTEIN BAD; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN BID; PROTEIN BOH; PROTEIN MCL 1; PROTEIN MSH2; PROTEIN MTD; PROTEIN NOXA; PUMA PROTEIN; UNCLASSIFIED DRUG; XRCC1 PROTEIN;

ANTIBODY PRODUCTION; APOPTOSIS; AUTOSOME; CARCINOGENESIS; CELL CYCLE REGULATION; CELL DEATH; CELL SURVIVAL; CELL VIABILITY; CHROMOSOME REARRANGEMENT; DNA END JOINING REPAIR; DNA REPAIR; DOUBLE STRANDED DNA BREAK; EXCISION REPAIR; GENE MUTATION; GENETIC TRANSCRIPTION; GENOMIC INSTABILITY; HOMOLOGOUS RECOMBINATION; HUMAN; IMMUNOGLOBULIN GENE; MISMATCH REPAIR; MITOCHONDRION; MOLECULAR EVOLUTION; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; REGULATORY MECHANISM; RETROVIRUS; REVIEW; RNA TRANSLATION; STOICHIOMETRY; TRANSCRIPTION REGULATION; UBIQUITINATION; VIRUS DNA CELL DNA INTERACTION; X CHROMOSOME INACTIVATION;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BRCA1 PROTEIN; DNA REPAIR; EVOLUTION, MOLECULAR; GENES, BCL-2; GENOMIC INSTABILITY; HUMANS; MUTAGENESIS; NEOPLASMS;

EID: 84865644725     PISSN: 13835742     EISSN: 13882139     Source Type: Journal    
DOI: 10.1016/j.mrrev.2012.05.002     Document Type: Review

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