Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer.

Genome biology

Volumn 12, Issue 10, 2011, Pages

  Kloosterman, Wigard P ^a   Hoogstraat, Marlous ^b   Paling, Oscar ^b   Tavakoli Yaraki, Masoumeh ^b   Renkens, Ivo ^b   Vermaat, Joost S ^b   van Roosmalen, Markus J ^b   van Lieshout, Stef ^b   Nijman, Isaac J ^b   Roessingh, Wijnand ^b   van 't Slot, Ruben ^b   van de Belt, José ^b   Guryev, Victor ^b   Koudijs, Marco ^b   Voest, Emile ^b   Cuppen, Edwin ^b  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DNA BINDING PROTEIN; EXO1 PROTEIN, HUMAN; EXODEOXYRIBONUCLEASE; MLL3 PROTEIN, HUMAN; NOTCH2 PROTEIN, HUMAN; NOTCH2 RECEPTOR; POLYDEOXYRIBONUCLEOTIDE SYNTHASE;

ARTICLE; BIOLOGY; CASE CONTROL STUDY; CHROMOSOME ABERRATION; COLORECTAL TUMOR; FEMALE; GENE DOSAGE; GENE FREQUENCY; GENE REARRANGEMENT; GENETICS; HUMAN; HUMAN CHROMOSOME; LIVER TUMOR; MALE; METASTASIS; PATHOLOGY; POINT MUTATION; SINGLE NUCLEOTIDE POLYMORPHISM; TUMOR GENE;

CASE-CONTROL STUDIES; CHROMOSOME ABERRATIONS; CHROMOSOMES, HUMAN; COLORECTAL NEOPLASMS; COMPUTATIONAL BIOLOGY; DNA REPAIR ENZYMES; DNA, NEOPLASM; DNA-BINDING PROTEINS; EXODEOXYRIBONUCLEASES; FEMALE; GENE DOSAGE; GENE FREQUENCY; GENE REARRANGEMENT; GENES, NEOPLASM; HUMANS; LIVER NEOPLASMS; MALE; POINT MUTATION; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTOR, NOTCH2;

EID: 80054698731     PISSN: None     EISSN: 14656914     Source Type: Journal    
DOI: 10.1186/gb-2011-12-10-r103     Document Type: Article

References (0)