메뉴 건너뛰기




Volumn 164, Issue 4, 2016, Pages 644-655

Long Neural Genes Harbor Recurrent DNA Break Clusters in Neural Stem/Progenitor Cells

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA CATENIN; APHIDICOLIN; ATM PROTEIN; CADHERIN; DIMETHYL SULFOXIDE; PROTEIN P53; XRCC4 PROTEIN; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; LIMBIC SYSTEM-ASSOCIATED MEMBRANE PROTEIN; NERVE CELL ADHESION MOLECULE; NERVE PROTEIN; NPAS3 PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

EID: 84958157371     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2015.12.039     Document Type: Article
Times cited : (206)

References (55)
  • 2
    • 84873320525 scopus 로고    scopus 로고
    • Mechanisms of programmed DNA lesions and genomic instability in the immune system
    • F.W. Alt, Y. Zhang, F.L. Meng, C. Guo, and B. Schwer Mechanisms of programmed DNA lesions and genomic instability in the immune system Cell 152 2013 417 429
    • (2013) Cell , vol.152 , pp. 417-429
    • Alt, F.W.1    Zhang, Y.2    Meng, F.L.3    Guo, C.4    Schwer, B.5
  • 3
    • 84866906311 scopus 로고    scopus 로고
    • De novo CNV formation in mouse embryonic stem cells occurs in the absence of Xrcc4-dependent nonhomologous end joining
    • M.F. Arlt, S. Rajendran, S.R. Birkeland, T.E. Wilson, and T.W. Glover De novo CNV formation in mouse embryonic stem cells occurs in the absence of Xrcc4-dependent nonhomologous end joining PLoS Genet. 8 2012 e1002981
    • (2012) PLoS Genet. , vol.8 , pp. e1002981
    • Arlt, M.F.1    Rajendran, S.2    Birkeland, S.R.3    Wilson, T.E.4    Glover, T.W.5
  • 5
    • 0032585526 scopus 로고    scopus 로고
    • Targeted disruption of the gene encoding DNA ligase IV leads to lethality in embryonic mice
    • D.E. Barnes, G. Stamp, I. Rosewell, A. Denzel, and T. Lindahl Targeted disruption of the gene encoding DNA ligase IV leads to lethality in embryonic mice Curr. Biol. 8 1998 1395 1398
    • (1998) Curr. Biol. , vol.8 , pp. 1395-1398
    • Barnes, D.E.1    Stamp, G.2    Rosewell, I.3    Denzel, A.4    Lindahl, T.5
  • 6
    • 84867386682 scopus 로고    scopus 로고
    • Classical and alternative end-joining pathways for repair of lymphocyte-specific and general DNA double-strand breaks
    • C. Boboila, F.W. Alt, and B. Schwer Classical and alternative end-joining pathways for repair of lymphocyte-specific and general DNA double-strand breaks Adv. Immunol. 116 2012 1 49
    • (2012) Adv. Immunol. , vol.116 , pp. 1-49
    • Boboila, C.1    Alt, F.W.2    Schwer, B.3
  • 7
    • 77956147463 scopus 로고    scopus 로고
    • Characterization of FRA7B, a human common fragile site mapped at the 7p chromosome terminal region
    • N. Bosco, F. Pelliccia, and A. Rocchi Characterization of FRA7B, a human common fragile site mapped at the 7p chromosome terminal region Cancer Genet. Cytogenet. 202 2010 47 52
    • (2010) Cancer Genet. Cytogenet. , vol.202 , pp. 47-52
    • Bosco, N.1    Pelliccia, F.2    Rocchi, A.3
  • 9
    • 57849109058 scopus 로고    scopus 로고
    • Nascent RNA sequencing reveals widespread pausing and divergent initiation at human promoters
    • L.J. Core, J.J. Waterfall, and J.T. Lis Nascent RNA sequencing reveals widespread pausing and divergent initiation at human promoters Science 322 2008 1845 1848
    • (2008) Science , vol.322 , pp. 1845-1848
    • Core, L.J.1    Waterfall, J.J.2    Lis, J.T.3
  • 13
    • 84904565384 scopus 로고    scopus 로고
    • Mobile DNA elements in the generation of diversity and complexity in the brain
    • J.A. Erwin, M.C. Marchetto, and F.H. Gage Mobile DNA elements in the generation of diversity and complexity in the brain Nat. Rev. Neurosci. 15 2014 497 506
    • (2014) Nat. Rev. Neurosci. , vol.15 , pp. 497-506
    • Erwin, J.A.1    Marchetto, M.C.2    Gage, F.H.3
  • 16
    • 84923275611 scopus 로고    scopus 로고
    • Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases
    • R.L. Frock, J. Hu, R.M. Meyers, Y.J. Ho, E. Kii, and F.W. Alt Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases Nat. Biotechnol. 33 2015 179 186
    • (2015) Nat. Biotechnol. , vol.33 , pp. 179-186
    • Frock, R.L.1    Hu, J.2    Meyers, R.M.3    Ho, Y.J.4    Kii, E.5    Alt, F.W.6
  • 17
    • 84922080153 scopus 로고    scopus 로고
    • Very large common fragile site genes and their potential role in cancer development
    • G. Gao, and D.I. Smith Very large common fragile site genes and their potential role in cancer development Cell. Mol. Life Sci. 71 2014 4601 4615
    • (2014) Cell. Mol. Life Sci. , vol.71 , pp. 4601-4615
    • Gao, G.1    Smith, D.I.2
  • 20
    • 79959267641 scopus 로고    scopus 로고
    • Unique and redundant functions of ATM and DNA-PKcs during V(D)J recombination
    • E.J. Gapud, and B.P. Sleckman Unique and redundant functions of ATM and DNA-PKcs during V(D)J recombination Cell Cycle 10 2011 1928 1935
    • (2011) Cell Cycle , vol.10 , pp. 1928-1935
    • Gapud, E.J.1    Sleckman, B.P.2
  • 21
    • 0021278143 scopus 로고
    • DNA polymerase alpha inhibition by aphidicolin induces gaps and breaks at common fragile sites in human chromosomes
    • T.W. Glover, C. Berger, J. Coyle, and B. Echo DNA polymerase alpha inhibition by aphidicolin induces gaps and breaks at common fragile sites in human chromosomes Hum. Genet. 67 1984 136 142
    • (1984) Hum. Genet. , vol.67 , pp. 136-142
    • Glover, T.W.1    Berger, C.2    Coyle, J.3    Echo, B.4
  • 22
    • 33749384368 scopus 로고    scopus 로고
    • Common fragile sites are conserved features of human and mouse chromosomes and relate to large active genes
    • A. Helmrich, K. Stout-Weider, K. Hermann, E. Schrock, and T. Heiden Common fragile sites are conserved features of human and mouse chromosomes and relate to large active genes Genome Res. 16 2006 1222 1230
    • (2006) Genome Res. , vol.16 , pp. 1222-1230
    • Helmrich, A.1    Stout-Weider, K.2    Hermann, K.3    Schrock, E.4    Heiden, T.5
  • 23
    • 84255198334 scopus 로고    scopus 로고
    • Collisions between replication and transcription complexes cause common fragile site instability at the longest human genes
    • A. Helmrich, M. Ballarino, and L. Tora Collisions between replication and transcription complexes cause common fragile site instability at the longest human genes Mol. Cell 44 2011 966 977
    • (2011) Mol. Cell , vol.44 , pp. 966-977
    • Helmrich, A.1    Ballarino, M.2    Tora, L.3
  • 27
    • 84857191660 scopus 로고    scopus 로고
    • Transcription as a source of genome instability
    • N. Kim, and S. Jinks-Robertson Transcription as a source of genome instability Nat. Rev. Genet. 13 2012 204 214
    • (2012) Nat. Rev. Genet. , vol.13 , pp. 204-214
    • Kim, N.1    Jinks-Robertson, S.2
  • 29
    • 0021047844 scopus 로고
    • Transposition and amplification of oncogene-related sequences in human neuroblastomas
    • N.E. Kohl, N. Kanda, R.R. Schreck, G. Bruns, S.A. Latt, F. Gilbert, and F.W. Alt Transposition and amplification of oncogene-related sequences in human neuroblastomas Cell 35 1983 359 367
    • (1983) Cell , vol.35 , pp. 359-367
    • Kohl, N.E.1    Kanda, N.2    Schreck, R.R.3    Bruns, G.4    Latt, S.A.5    Gilbert, F.6    Alt, F.W.7
  • 30
    • 0036266065 scopus 로고    scopus 로고
    • The common fragile site FRA16D and its associated gene WWOX are highly conserved in the mouse at Fra8E1
    • K.A. Krummel, S.R. Denison, E. Calhoun, L.A. Phillips, and D.I. Smith The common fragile site FRA16D and its associated gene WWOX are highly conserved in the mouse at Fra8E1 Genes Chromosomes Cancer 34 2002 154 167
    • (2002) Genes Chromosomes Cancer , vol.34 , pp. 154-167
    • Krummel, K.A.1    Denison, S.R.2    Calhoun, E.3    Phillips, L.A.4    Smith, D.I.5
  • 32
    • 84881615685 scopus 로고    scopus 로고
    • Common fragile site profiling in epithelial and erythroid cells reveals that most recurrent cancer deletions lie in fragile sites hosting large genes
    • B. Le Tallec, G.A. Millot, M.E. Blin, O. Brison, B. Dutrillaux, and M. Debatisse Common fragile site profiling in epithelial and erythroid cells reveals that most recurrent cancer deletions lie in fragile sites hosting large genes Cell Rep. 4 2013 420 428
    • (2013) Cell Rep. , vol.4 , pp. 420-428
    • Le Tallec, B.1    Millot, G.A.2    Blin, M.E.3    Brison, O.4    Dutrillaux, B.5    Debatisse, M.6
  • 34
    • 0037112505 scopus 로고    scopus 로고
    • DNA ligase IV suppresses medulloblastoma formation
    • Y. Lee, and P.J. McKinnon DNA ligase IV suppresses medulloblastoma formation Cancer Res. 62 2002 6395 6399
    • (2002) Cancer Res. , vol.62 , pp. 6395-6399
    • Lee, Y.1    McKinnon, P.J.2
  • 35
    • 77953229115 scopus 로고    scopus 로고
    • The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway
    • M.R. Lieber The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway Annu. Rev. Biochem. 79 2010 181 211
    • (2010) Annu. Rev. Biochem. , vol.79 , pp. 181-211
    • Lieber, M.R.1
  • 38
    • 84886867688 scopus 로고    scopus 로고
    • Maintaining genome stability in the nervous system
    • P.J. McKinnon Maintaining genome stability in the nervous system Nat. Neurosci. 16 2013 1523 1529
    • (2013) Nat. Neurosci. , vol.16 , pp. 1523-1529
    • McKinnon, P.J.1
  • 40
    • 33745593721 scopus 로고    scopus 로고
    • Generation of neuronal variability and complexity
    • A.R. Muotri, and F.H. Gage Generation of neuronal variability and complexity Nature 441 2006 1087 1093
    • (2006) Nature , vol.441 , pp. 1087-1093
    • Muotri, A.R.1    Gage, F.H.2
  • 42
    • 84924384551 scopus 로고    scopus 로고
    • Mechanisms of ATM Activation
    • T.T. Paull Mechanisms of ATM Activation Annu. Rev. Biochem. 84 2015 711 738
    • (2015) Annu. Rev. Biochem. , vol.84 , pp. 711-738
    • Paull, T.T.1
  • 43
    • 84879756120 scopus 로고    scopus 로고
    • Somatic mutation, genomic variation, and neurological disease
    • A. Poduri, G.D. Evrony, X. Cai, and C.A. Walsh Somatic mutation, genomic variation, and neurological disease Science 341 2013 1237758
    • (2013) Science , vol.341 , pp. 1237758
    • Poduri, A.1    Evrony, G.D.2    Cai, X.3    Walsh, C.A.4
  • 47
    • 77952994784 scopus 로고    scopus 로고
    • Evolutionarily conserved replication timing profiles predict long-range chromatin interactions and distinguish closely related cell types
    • T. Ryba, I. Hiratani, J. Lu, M. Itoh, M. Kulik, J. Zhang, T.C. Schulz, A.J. Robins, S. Dalton, and D.M. Gilbert Evolutionarily conserved replication timing profiles predict long-range chromatin interactions and distinguish closely related cell types Genome Res. 20 2010 761 770
    • (2010) Genome Res. , vol.20 , pp. 761-770
    • Ryba, T.1    Hiratani, I.2    Lu, J.3    Itoh, M.4    Kulik, M.5    Zhang, J.6    Schulz, T.C.7    Robins, A.J.8    Dalton, S.9    Gilbert, D.M.10
  • 48
    • 84911915086 scopus 로고    scopus 로고
    • Molecular characterization of common fragile sites as a strategy to discover cancer susceptibility genes
    • L. Savelyeva, and L.M. Brueckner Molecular characterization of common fragile sites as a strategy to discover cancer susceptibility genes Cell. Mol. Life Sci. 71 2014 4561 4575
    • (2014) Cell. Mol. Life Sci. , vol.71 , pp. 4561-4575
    • Savelyeva, L.1    Brueckner, L.M.2
  • 49
    • 84958205734 scopus 로고    scopus 로고
    • Transcription-associated processes cause DNA double-strand breaks and translocations in neural stem/progenitor cells
    • Published online February 12, 2016
    • B. Schwer, P. Wei, A.N. Chang, J. Kao, Z. Du, R.M. Meyers, and F.W. Alt Transcription-associated processes cause DNA double-strand breaks and translocations in neural stem/progenitor cells Proc. Natl. Acad. Sci. USA. 2016 10.1073/pnas.1525564113 Published online February 12, 2016
    • (2016) Proc. Natl. Acad. Sci. USA.
    • Schwer, B.1    Wei, P.2    Chang, A.N.3    Kao, J.4    Du, Z.5    Meyers, R.M.6    Alt, F.W.7
  • 50
    • 62249199182 scopus 로고    scopus 로고
    • ReplicationDomain: A visualization tool and comparative database for genome-wide replication timing data
    • N. Weddington, A. Stuy, I. Hiratani, T. Ryba, T. Yokochi, and D.M. Gilbert ReplicationDomain: a visualization tool and comparative database for genome-wide replication timing data BMC Bioinformatics 9 2008 530
    • (2008) BMC Bioinformatics , vol.9 , pp. 530
    • Weddington, N.1    Stuy, A.2    Hiratani, I.3    Ryba, T.4    Yokochi, T.5    Gilbert, D.M.6
  • 52
    • 67650711619 scopus 로고    scopus 로고
    • A clustering approach for identification of enriched domains from histone modification ChIP-Seq data
    • C. Zang, D.E. Schones, C. Zeng, K. Cui, K. Zhao, and W. Peng A clustering approach for identification of enriched domains from histone modification ChIP-Seq data Bioinformatics 25 2009 1952 1958
    • (2009) Bioinformatics , vol.25 , pp. 1952-1958
    • Zang, C.1    Schones, D.E.2    Zeng, C.3    Cui, K.4    Zhao, K.5    Peng, W.6
  • 55
    • 0037188898 scopus 로고    scopus 로고
    • Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations
    • C. Zhu, K.D. Mills, D.O. Ferguson, C. Lee, J. Manis, J. Fleming, Y. Gao, C.C. Morton, and F.W. Alt Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations Cell 109 2002 811 821
    • (2002) Cell , vol.109 , pp. 811-821
    • Zhu, C.1    Mills, K.D.2    Ferguson, D.O.3    Lee, C.4    Manis, J.5    Fleming, J.6    Gao, Y.7    Morton, C.C.8    Alt, F.W.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.