BRCA1-Ku80 protein interaction enhances end-joining fidelity of chromosomal double-strand breaks in the G1 phase of the cell cycle

Journal of Biological Chemistry

Volumn 288, Issue 13, 2013, Pages 8966-8976

  Jiang, Guochun ^a   Plo, Isabelle ^b,c   Wang, Tong ^d   Rahman, Mohammad ^a   Cho, Ju Hwan ^a   Yang, Eddy ^e   Lopez, Bernard S ^b,c   Xia, Fen ^a  

^a THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER   (United States)

^b CNRS   (France)

^c INSTITUT DE RADIOBIOLOGIE CELLULAIRE ET MOLÉCULAIRE   (France)

^d VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e The University of Alabama at Birmingham   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA DOUBLE-STRAND BREAKS; DOUBLE-STRAND BREAKS; HOMOLOGOUS RECOMBINATION; INTEGRITY MAINTENANCE; NONHOMOLOGOUS END JOINING; PROTEIN INTERACTION; RADIATION-INDUCED; TUMOR SUPPRESSORS;

CHROMOSOMES; JOINING; MACHINERY;

REPAIR;

BRCA1 PROTEIN; KU ANTIGEN; PROTEIN KU80; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CANONICAL NON HOMOLOGOUS END JOINING REPAIR; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CHROMOSOME DAMAGE; CONTROLLED STUDY; DNA END JOINING REPAIR; DOUBLE STRANDED DNA BREAK; GENETIC PARAMETERS; GENOME INTEGRITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; RECOMBINATION REPAIR;

ANTIGENS, NUCLEAR; BRCA1 PROTEIN; CELL CYCLE; CHROMATIN IMMUNOPRECIPITATION; DNA; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; DNA-BINDING PROTEINS; G1 PHASE; GENE DELETION; GLUTATHIONE TRANSFERASE; HEK293 CELLS; HUMANS; MUTAGENESIS; NUCLEAR PROTEINS; PROTEIN BINDING; RECOMBINATION, GENETIC; SIGNAL TRANSDUCTION;

EID: 84875998428     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.412650     Document Type: Article

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