Bloom's syndrome and PICH helicases cooperate with topoisomerase IIα in centromere disjunction before anaphase

PLoS ONE

Volumn 7, Issue 4, 2012, Pages

  Rouzeau, Sébastien ^a,b   Cordelières, Fabrice P ^a,b   Buhagiar Labarchède, Géraldine ^a,b   Hurbain, Ilse ^a,c   Onclercq Delic, Rosine ^a,b   Gemble, Simon ^a,b   Magnaghi Jaulin, Laura ^d   Jaulin, Christian ^d   Amor Guéret, Mounira ^a,b  

^a INSTITUT CURIE   (France)

^b CNRS UMR3348   (France)

^c INSTITUT CURIE   (France)

^d UNIVERSITÉ DE RENNES 1   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOM SYNDROME HELICASE; CENTROMERE PROTEIN A; COHESIN; DNA TOPOISOMERASE (ATP HYDROLYSING); DNA TOPOISOMERASE (ATP HYDROLYSING) ALPHA; DNA TOPOISOMERASE (ATP HYDROLYSING) ALPHA INHIBITOR; GYRASE INHIBITOR; HELICASE; PLK1 INTERACTING CHECKPOINT HELICASE; UNCLASSIFIED DRUG; CATENATED DNA; CELL CYCLE PROTEIN; COHESINS; DNA BINDING PROTEIN; DNA TOPOISOMERASE II ALPHA; ERCC6L PROTEIN, HUMAN; NONHISTONE PROTEIN; RECQ HELICASE; SMALL INTERFERING RNA; TUMOR ANTIGEN;

ANAPHASE; ARTICLE; CATENATION; CELL CYCLE G2 PHASE; CELL JUNCTION; CENTROMERE; CHEMICAL PARAMETERS; CHROMATIN IMMUNOPRECIPITATION; CHROMOSOME STRUCTURE; CONTROLLED STUDY; DECATENATION; ELECTRON MICROSCOPY; ENZYME ANALYSIS; ENZYME SPECIFICITY; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HUMAN CELL; MITOSIS; PROMETAPHASE; PROTEIN DEPLETION; RNA INTERFERENCE; CHEMISTRY; CHROMOSOME; DRUG ANTAGONISM; ENZYMOLOGY; GENETICS; HELA CELL; METABOLISM; SITE DIRECTED MUTAGENESIS;

ANAPHASE; ANTIGENS, NEOPLASM; CELL CYCLE PROTEINS; CENTROMERE; CHROMOSOMAL PROTEINS, NON-HISTONE; CHROMOSOMES; DNA HELICASES; DNA TOPOISOMERASES, TYPE II; DNA, CATENATED; DNA-BINDING PROTEINS; G2 PHASE; HELA CELLS; HUMANS; MITOSIS; MUTAGENESIS, SITE-DIRECTED; PROMETAPHASE; RECQ HELICASES; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 84860382314     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0033905     Document Type: Article

References (32)

1. Carroll CW, Straight AF, (2006) Centromere formation: from epigenetics to self-assembly. Trends Cell Biol 16: 70-78.
2. Cleveland DW, Mao Y, Sullivan KF, (2003) Centromeres and kinetochores: from epigenetics to mitotic checkpoint signaling. Cell 112: 407-421.
3. Yuen KW, Montpetit B, Hieter P, (2005) The kinetochore and cancer: what's the connection? Curr Opin Cell Biol 17: 576-582.
4. Baumann C, Korner R, Hofmann K, Nigg EA, (2007) PICH, a centromere-associated SNF2 family ATPase, is regulated by Plk1 and required for the spindle checkpoint. Cell 128: 101-114.
5. Chan KL, North PS, Hickson ID, (2007) BLM is required for faithful chromosome segregation and its localization defines a class of ultrafine anaphase bridges. EMBO J 26: 3397-3409.
6. Wang LH, Schwarzbraun T, Speicher MR, Nigg EA, (2008) Persistence of DNA threads in human anaphase cells suggests late completion of sister chromatid decatenation. Chromosoma 117: 123-135.
7. Wang LH, Mayer B, Stemmann O, Nigg EA, (2010) Centromere DNA decatenation depends on cohesin removal and is required for mammalian cell division. J Cell Sci 123: 806-813.
8. Amor-Gueret M, (2006) Bloom syndrome, genomic instability and cancer: the SOS-like hypothesis. Cancer Lett 236: 1-12.
9. Ke Y, Huh JW, Warrington R, Li B, Wu N, et al. (2011) PICH and BLM limit histone association with anaphase centromeric DNA threads and promote their resolution. EMBO J 30: 3309-3321.
10. Chabosseau P, Buhagiar-Labarchede G, Onclercq-Delic R, Lambert S, Debatisse M, et al. (2011) Pyrimidine pool imbalance induced by BLM helicase deficiency contributes to genetic instability in Bloom syndrome. Nat Commun 2: 368.
11. Yankiwski V, Marciniak RA, Guarente L, Neff NF, (2000) Nuclear structure in normal and Bloom syndrome cells. Proc Natl Acad Sci U S A 97: 5214-5219.
12. Pines J, Hunter T, (1991) Human cyclins A and B1 are differentially located in the cell and undergo cell cycle-dependent nuclear transport. J Cell Biol 115: 1-17.
13. Guo RB, Rigolet P, Ren H, Zhang B, Zhang XD, et al. (2007) Structural and functional analyses of disease-causing missense mutations in Bloom syndrome protein. Nucleic Acids Res 35: 6297-6310.
14. Batram C, Baddeley D, Kreth G, Cremer C, (2008) High precision size measurement of centromere 8 and the 8q24/c-myc gene region in metaphase and interphase human fibroblasts indicate differential condensation. J Struct Biol 164: 293-303.
15. Ke Y, Huh JW, Warrington R, Li B, Wu N, et al. (2011) PICH and BLM limit histone association with anaphase centromeric DNA threads and promote their resolution. EMBO J 30: 3309-3021.
16. Diaz-Martinez LA, Gimenez-Abian JF, Clarke DJ, (2008) Chromosome cohesion- rings, knots, orcs and fellowship. J Cell Sci 121: 2107-2114.
17. Chan KL, Hickson ID, (2011) New insights into the formation and resolution of ultra-fine anaphase bridges. Semin Cell Dev Biol 22: 906-912.
18. Sano K, Miyaji-Yamaguchi M, Tsutsui KM, Tsutsui K, (2008) Topoisomerase IIbeta activates a subset of neuronal genes that are repressed in AT-rich genomic environment. PLoS One 3: e4103.
19. Baxter J, Sen N, Martinez VL, De Carandini ME, Schvartzman JB, et al. (2011) Positive supercoiling of mitotic DNA drives decatenation by topoisomerase II in eukaryotes. Science 331: 1328-1332.
20. Eladad S, Ye TZ, Hu P, Leversha M, Beresten S, et al. (2005) Intra-nuclear trafficking of the BLM helicase to DNA damage-induced foci is regulated by SUMO modification. Hum Mol Genet 14: 1351-1365.
21. Lahkim Bennani-Belhaj K, Rouzeau S, Buhagiar-Labarchede G, Chabosseau P, Onclercq-Delic R, et al. (2010) The Bloom syndrome protein limits the lethality associated with RAD51 deficiency. Mol Cancer Res 8: 385-394.
22. Hubner NC, Wang LH, Kaulich M, Descombes P, Poser I, et al. (2010) Re-examination of siRNA specificity questions role of PICH and Tao1 in the spindle checkpoint and identifies Mad2 as a sensitive target for small RNAs. Chromosoma 119: 149-165.
23. Ababou M, Dumaire V, Lecluse Y, Amor-Gueret M, (2002) Cleavage of BLM and sensitivity of Bloom's syndrome cells to hydroxurea and UV-C radiation. Cell Cycle 1: 262-266.
24. Bustin SA, Benes V, Garson JA, Hellemans J, Huggett J, et al. (2009) The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments. Clin Chem 55: 611-622.
25. Vandesompele J, De Preter K, Pattyn F, Poppe B, Van Roy N, et al. (2002) Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 3: RESEARCH0034.
26. Viegas MH, Gehring NH, Breit S, Hentze MW, Kulozik AE, (2007) The abundance of RNPS1, a protein component of the exon junction complex, can determine the variability in efficiency of the Nonsense Mediated Decay pathway. Nucleic Acids Res 35: 4542-4551.
27. Eot-Houllier G, Fulcrand G, Watanabe Y, Magnaghi-Jaulin L, Jaulin C, (2008) Histone deacetylase 3 is required for centromeric H3K4 deacetylation and sister chromatid cohesion. Genes Dev 22: 2639-2644.
28. Savino TM, Gebrane-Younes J, De Mey J, Sibarita JB, Hernandez-Verdun D, (2001) Nucleolar assembly of the rRNA processing machinery in living cells. J Cell Biol 153: 1097-1110.
29. Agostinho M, Rino J, Braga J, Ferreira F, Steffensen S, et al. (2004) Human topoisomerase IIalpha: targeting to subchromosomal sites of activity during interphase and mitosis. Mol Biol Cell 15: 2388-2400.
30. Bolte S, Cordelieres FP, (2006) A guided tour into subcellular colocalization analysis in light microscopy. J Microsc 224: 213-232.
31. Warburton PE, Greig GM, Haaf T, Willard HF, (1991) PCR amplification of chromosome-specific alpha satellite DNA: definition of centromeric STS markers and polymorphic analysis. Genomics 11: 324-333.
32. Jolly C, Metz A, Govin J, Vigneron M, Turner BM, et al. (2004) Stress-induced transcription of satellite III repeats. J Cell Biol 164: 25-33.